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Items: 1 to 50 of 111

1.

Postnatal Zika virus infection of nonhuman primate infants born to mothers infected with homologous Brazilian Zika virus.

Maness NJ, Schouest B, Singapuri A, Dennis M, Gilbert MH, Bohm RP, Schiro F, Aye PP, Baker K, Van Rompay KKA, Lackner AA, Bonaldo MC, Blair RV, Permar SR, Coffey LL, Panganiban AT, Magnani D.

Sci Rep. 2019 Sep 5;9(1):12802. doi: 10.1038/s41598-019-49209-7.

2.

Analytical Treatment Interruption after Short-Term Antiretroviral Therapy in a Postnatally Simian-Human Immunodeficiency Virus-Infected Infant Rhesus Macaque Model.

Goswami R, Nelson AN, Tu JJ, Dennis M, Feng L, Kumar A, Mangold J, Mangan RJ, Mattingly C, Curtis AD 2nd, Obregon-Perko V, Mavigner M, Pollara J, Shaw GM, Bar KJ, Chahroudi A, De Paris K, Chan C, Van Rompay KKA, Permar SR.

MBio. 2019 Sep 5;10(5). pii: e01971-19. doi: 10.1128/mBio.01971-19.

3.

Efficient transplacental IgG transfer in women infected with Zika virus during pregnancy.

Singh T, Lopez CA, Giuberti C, Dennis ML, Itell HL, Heimsath HJ, Webster HS, Roark HK, Merçon de Vargas PR, Hall A, Corey RG, Swamy GK, Dietze R, Lazear HM, Permar SR.

PLoS Negl Trop Dis. 2019 Aug 26;13(8):e0007648. doi: 10.1371/journal.pntd.0007648. eCollection 2019 Aug.

4.

Primary infection with dengue or Zika virus does not affect the severity of heterologous secondary infection in macaques.

Breitbach ME, Newman CM, Dudley DM, Stewart LM, Aliota MT, Koenig MR, Shepherd PM, Yamamoto K, Crooks CM, Young G, Semler MR, Weiler AM, Barry GL, Heimsath H, Mohr EL, Eichkoff J, Newton W, Peterson E, Schultz-Darken N, Permar SR, Dean H, Capuano S 3rd, Osorio JE, Friedrich TC, O'Connor DH.

PLoS Pathog. 2019 Aug 1;15(8):e1007766. doi: 10.1371/journal.ppat.1007766. eCollection 2019 Aug.

5.

Cultivating Research Skills During Clinical Training to Promote Pediatric-Scientist Development.

Hurst JH, Barrett KJ, Kelly MS, Staples BB, McGann KA, Cunningham CK, Reed AM, Gbadegesin RA, Permar SR.

Pediatrics. 2019 Aug;144(2). pii: e20190745. doi: 10.1542/peds.2019-0745.

PMID:
31363070
6.

Fc Characteristics Mediate Selective Placental Transfer of IgG in HIV-Infected Women.

Martinez DR, Fong Y, Li SH, Yang F, Jennewein MF, Weiner JA, Harrell EA, Mangold JF, Goswami R, Seage GR 3rd, Alter G, Ackerman ME, Peng X, Fouda GG, Permar SR.

Cell. 2019 Jun 27;178(1):190-201.e11. doi: 10.1016/j.cell.2019.05.046. Epub 2019 Jun 13.

7.

Humoral Immune Correlates for Prevention of Postnatal Cytomegalovirus Acquisition.

Saccoccio FM, Jenks JA, Itell HL, Li SH, Berry M, Pollara J, Casper C, Gantt S, Permar SR.

J Infect Dis. 2019 Jul 31;220(5):772-780. doi: 10.1093/infdis/jiz192.

PMID:
31107951
8.

Simian-Human Immunodeficiency Virus SHIV.CH505-Infected Infant and Adult Rhesus Macaques Exhibit Similar Env-Specific Antibody Kinetics, despite Distinct T-Follicular Helper and Germinal Center B Cell Landscapes.

Nelson AN, Goswami R, Dennis M, Tu J, Mangan RJ, Saha PT, Cain DW, Curtis AD, Shen X, Shaw GM, Bar K, Hudgens M, Pollara J, De Paris K, Van Rompay KKA, Permar SR.

J Virol. 2019 Jul 17;93(15). pii: e00168-19. doi: 10.1128/JVI.00168-19. Print 2019 Aug 1.

PMID:
31092583
9.

Optimized Mucosal Modified Vaccinia Virus Ankara Prime/Soluble gp120 Boost HIV Vaccination Regimen Induces Antibody Responses Similar to Those of an Intramuscular Regimen.

Jones DI, Pollara JJ, Johnson-Weaver BT, LaBranche CC, Montefiori DC, Pickup DJ, Permar SR, Abraham SN, Maddaloni M, Pascual DW, Staats HF.

J Virol. 2019 Jun 28;93(14). pii: e00475-19. doi: 10.1128/JVI.00475-19. Print 2019 Jul 15.

PMID:
31068425
10.

Determinants of Tenascin-C and HIV-1 envelope binding and neutralization.

Mangan RJ, Stamper L, Ohashi T, Eudailey JA, Go EP, Jaeger FH, Itell HL, Watts BE, Fouda GG, Erickson HP, Alam SM, Desaire H, Permar SR.

Mucosal Immunol. 2019 Jul;12(4):1004-1012. doi: 10.1038/s41385-019-0164-2. Epub 2019 Apr 11.

PMID:
30976088
11.

Bridging Vaccine-Induced HIV-1 Neutralizing and Effector Antibody Responses in Rabbit and Rhesus Macaque Animal Models.

Pollara J, Jones DI, Huffman T, Edwards RW, Dennis M, Li SH, Jha S, Goodman D, Kumar A, LaBranche CC, Montefiori DC, Fouda GG, Hope TJ, Tomaras GD, Staats HF, Ferrari G, Permar SR.

J Virol. 2019 May 1;93(10). pii: e02119-18. doi: 10.1128/JVI.02119-18. Print 2019 May 15.

12.

Mercury Exposure and Poor Nutritional Status Reduce Response to Six Expanded Program on Immunization Vaccines in Children: An Observational Cohort Study of Communities Affected by Gold Mining in the Peruvian Amazon.

Wyatt L, Permar SR, Ortiz E, Berky A, Woods CW, Amouou GF, Itell H, Hsu-Kim H, Pan W.

Int J Environ Res Public Health. 2019 Feb 21;16(4). pii: E638. doi: 10.3390/ijerph16040638.

13.

Rare Detection of Antiviral Functions of Polyclonal IgA Isolated from Plasma and Breast Milk Compartments in Women Chronically Infected with HIV-1.

Tay MZ, Kunz EL, Deal A, Zhang L, Seaton KE, Rountree W, Eudailey JA, Heptinstall J, McRaven MD, Matias E, McGuire E, Yates NL, Perez LG, Montefiori DC, Overman RG, Hope TJ, Shen X, Kalilani L, Fouda GG, Tomaras GD, Permar SR.

J Virol. 2019 Mar 21;93(7). pii: e02084-18. doi: 10.1128/JVI.02084-18. Print 2019 Apr 1.

14.

Intrahost Dynamics of Human Cytomegalovirus Variants Acquired by Seronegative Glycoprotein B Vaccinees.

Nelson CS, Vera Cruz D, Su M, Xie G, Vandergrift N, Pass RF, Forman M, Diener-West M, Koelle K, Arav-Boger R, Permar SR.

J Virol. 2019 Feb 19;93(5). pii: e01695-18. doi: 10.1128/JVI.01695-18. Print 2019 Mar 1.

15.

CMV Primes Functional Alternative Signaling in Adaptive Δg NK Cells but Is Subverted by Lentivirus Infection in Rhesus Macaques.

Shah SV, Manickam C, Ram DR, Kroll K, Itell H, Permar SR, Barouch DH, Klatt NR, Reeves RK.

Cell Rep. 2018 Dec 4;25(10):2766-2774.e3. doi: 10.1016/j.celrep.2018.11.020.

16.

Natural history of postnatal rhesus cytomegalovirus shedding by dams and acquisition by infant rhesus monkeys.

Kaur A, Itell HL, Ehlinger EP, Varner V, Gantt S, Permar SR.

PLoS One. 2018 Oct 24;13(10):e0206330. doi: 10.1371/journal.pone.0206330. eCollection 2018.

17.

Geographic and Racial Disparities in Infant Hearing Loss.

Lantos PM, Maradiaga-Panayotti G, Barber X, Raynor E, Tucci D, Hoffman K, Permar SR, Jackson P, Hughes BL, Kind A, Swamy GK.

Otolaryngol Head Neck Surg. 2018 Oct 9:194599818803305. doi: 10.1177/0194599818803305. [Epub ahead of print]

PMID:
30296906
18.

A new era in cytomegalovirus vaccinology: considerations for rational design of next-generation vaccines to prevent congenital cytomegalovirus infection.

Nelson CS, Herold BC, Permar SR.

NPJ Vaccines. 2018 Sep 20;3:38. doi: 10.1038/s41541-018-0074-4. eCollection 2018. Review.

19.

Noncanonical placental Fc receptors: What is their role in modulating transplacental transfer of maternal IgG?

Martinez DR, Fouda GG, Peng X, Ackerman ME, Permar SR.

PLoS Pathog. 2018 Aug 30;14(8):e1007161. doi: 10.1371/journal.ppat.1007161. eCollection 2018 Aug. No abstract available.

20.

Polyclonal HIV envelope-specific breast milk antibodies limit founder SHIV acquisition and cell-associated virus loads in infant rhesus monkeys.

Himes JE, Goswami R, Mangan RJ, Kumar A, Jeffries TL Jr, Eudailey JA, Heimsath H, Nguyen QN, Pollara J, LaBranche C, Chen M, Vandergrift NA, Peacock JW, Schiro F, Midkiff C, Ferrari G, Montefiori DC, Hernandez XA, Aye PP, Permar SR.

Mucosal Immunol. 2018 Nov;11(6):1716-1726. doi: 10.1038/s41385-018-0067-7. Epub 2018 Aug 16.

21.

Development and application of a multiplex assay for the simultaneous measurement of antibody responses elicited by common childhood vaccines.

Itell HL, McGuire EP, Muresan P, Cunningham CK, McFarland EJ, Borkowsky W, Permar SR, Fouda GG.

Vaccine. 2018 Sep 5;36(37):5600-5608. doi: 10.1016/j.vaccine.2018.07.048. Epub 2018 Aug 4.

22.

Reply to Gantt et al., "Higher Expectations for a Vaccine To Prevent Congenital Cytomegalovirus Infection".

Permar SR, Schleiss MR, Plotkin SA.

J Virol. 2018 Jul 17;92(15). pii: e00771-18. doi: 10.1128/JVI.00771-18. Print 2018 Aug 1. No abstract available.

23.

Tracking KLRC2 (NKG2C)+ memory-like NK cells in SIV+ and rhCMV+ rhesus macaques.

Ram DR, Manickam C, Hueber B, Itell HL, Permar SR, Varner V, Reeves RK.

PLoS Pathog. 2018 May 31;14(5):e1007104. doi: 10.1371/journal.ppat.1007104. eCollection 2018 May.

24.

HCMV glycoprotein B subunit vaccine efficacy mediated by nonneutralizing antibody effector functions.

Nelson CS, Huffman T, Jenks JA, Cisneros de la Rosa E, Xie G, Vandergrift N, Pass RF, Pollara J, Permar SR.

Proc Natl Acad Sci U S A. 2018 Jun 12;115(24):6267-6272. doi: 10.1073/pnas.1800177115. Epub 2018 Apr 30.

25.

Infant transmitted/founder HIV-1 viruses from peripartum transmission are neutralization resistant to paired maternal plasma.

Kumar A, Smith CEP, Giorgi EE, Eudailey J, Martinez DR, Yusim K, Douglas AO, Stamper L, McGuire E, LaBranche CC, Montefiori DC, Fouda GG, Gao F, Permar SR.

PLoS Pathog. 2018 Apr 19;14(4):e1006944. doi: 10.1371/journal.ppat.1006944. eCollection 2018 Apr.

26.

Predominant envelope variable loop 2-specific and gp120-specific antibody-dependent cellular cytotoxicity antibody responses in acutely SIV-infected African green monkeys.

Nguyen QN, Martinez DR, Himes JE, Whitney Edwards R, Han Q, Kumar A, Mangan R, Nicely NI, Xie G, Vandergrift N, Shen X, Pollara J, Permar SR.

Retrovirology. 2018 Mar 9;15(1):24. doi: 10.1186/s12977-018-0406-5.

27.

The Impact of IgG transplacental transfer on early life immunity.

Fouda GG, Martinez DR, Swamy GK, Permar SR.

Immunohorizons. 2018 Jan 1;2(1):14-25. doi: 10.4049/immunohorizons.1700057.

28.

Intranasal Live Influenza Vaccine Priming Elicits Localized B Cell Responses in Mediastinal Lymph Nodes.

Jegaskanda S, Mason RD, Andrews SF, Wheatley AK, Zhang R, Reynoso GV, Ambrozak DR, Santos CP, Luke CJ, Matsuoka Y, Brenchley JM, Hickman HD, Talaat KR, Permar SR, Liao HX, Yewdell JW, Koup RA, Roederer M, McDermott AB, Subbarao K.

J Virol. 2018 Apr 13;92(9). pii: e01970-17. doi: 10.1128/JVI.01970-17. Print 2018 May 1.

29.

Maternal HIV-1 Env Vaccination for Systemic and Breast Milk Immunity To Prevent Oral SHIV Acquisition in Infant Macaques.

Eudailey JA, Dennis ML, Parker ME, Phillips BL, Huffman TN, Bay CP, Hudgens MG, Wiseman RW, Pollara JJ, Fouda GG, Ferrari G, Pickup DJ, Kozlowski PA, Van Rompay KKA, De Paris K, Permar SR.

mSphere. 2018 Jan 10;3(1). pii: e00505-17. doi: 10.1128/mSphere.00505-17. eCollection 2018 Jan-Feb.

30.

Advancing Our Understanding of Protective Maternal Immunity as a Guide for Development of Vaccines To Reduce Congenital Cytomegalovirus Infections.

Permar SR, Schleiss MR, Plotkin SA.

J Virol. 2018 Mar 14;92(7). pii: e00030-18. doi: 10.1128/JVI.00030-18. Print 2018 Apr 1. Review.

31.

Effect of innate antiviral glycoproteins in breast milk on seroconversion to rotavirus vaccine (Rotarix) in children in Lusaka, Zambia.

Mwila-Kazimbaya K, Garcia MP, Bosomprah S, Laban NM, Chisenga CC, Permar SR, Simuyandi M, Munsaka S, Chilengi R.

PLoS One. 2017 Dec 28;12(12):e0189351. doi: 10.1371/journal.pone.0189351. eCollection 2017.

32.

Recent progress in immune-based interventions to prevent HIV-1 transmission to children.

Voronin Y, Jani I, Graham BS, Cunningham CK, Mofenson LM, Musoke PM, Permar SR, Scarlatti G.

J Int AIDS Soc. 2017 Dec;20(4). doi: 10.1002/jia2.25038.

33.

Development of Envelope Protein Antigens To Serologically Differentiate Zika Virus Infection from Dengue Virus Infection.

Premkumar L, Collins M, Graham S, Liou GA, Lopez CA, Jadi R, Balmaseda A, Brackbill JA, Dietze R, Camacho E, De Silva AD, Giuberti C, Dos Reis HL, Singh T, Heimsath H, Weiskopf D, Sette A, Osorio JE, Permar SR, Miley MJ, Lazear HM, Harris E, de Silva AM.

J Clin Microbiol. 2018 Feb 22;56(3). pii: e01504-17. doi: 10.1128/JCM.01504-17. Print 2018 Mar.

34.

Progress toward Development of a Vaccine against Congenital Cytomegalovirus Infection.

Schleiss MR, Permar SR, Plotkin SA.

Clin Vaccine Immunol. 2017 Dec 5;24(12). pii: e00268-17. doi: 10.1128/CVI.00268-17. Print 2017 Dec. Review.

35.

chngpt: threshold regression model estimation and inference.

Fong Y, Huang Y, Gilbert PB, Permar SR.

BMC Bioinformatics. 2017 Oct 16;18(1):454. doi: 10.1186/s12859-017-1863-x.

36.

HIV-Exposed Infants Vaccinated with an MF59/Recombinant gp120 Vaccine Have Higher-Magnitude Anti-V1V2 IgG Responses than Adults Immunized with the Same Vaccine.

McGuire EP, Fong Y, Toote C, Cunningham CK, McFarland EJ, Borkowsky W, Barnett S, Itell HL, Kumar A, Gray G, McElrath MJ, Tomaras GD, Permar SR, Fouda GG.

J Virol. 2017 Dec 14;92(1). pii: e01070-17. doi: 10.1128/JVI.01070-17. Print 2018 Jan 1.

37.

The Role of Maternal HIV Envelope-Specific Antibodies and Mother-to-Child Transmission Risk.

Douglas AO, Martinez DR, Permar SR.

Front Immunol. 2017 Sep 4;8:1091. doi: 10.3389/fimmu.2017.01091. eCollection 2017. Review.

38.

Rhesus monkeys for a nonhuman primate model of cytomegalovirus infections.

Itell HL, Kaur A, Deere JD, Barry PA, Permar SR.

Curr Opin Virol. 2017 Aug;25:126-133. doi: 10.1016/j.coviro.2017.08.005. Epub 2017 Sep 6. Review.

39.

Neighborhood Disadvantage is Associated with High Cytomegalovirus Seroprevalence in Pregnancy.

Lantos PM, Hoffman K, Permar SR, Jackson P, Hughes BL, Kind A, Swamy G.

J Racial Ethn Health Disparities. 2018 Aug;5(4):782-786. doi: 10.1007/s40615-017-0423-4. Epub 2017 Aug 24.

40.

HIV DNA-Adenovirus Multiclade Envelope Vaccine Induces gp41 Antibody Immunodominance in Rhesus Macaques.

Han Q, Williams WB, Saunders KO, Seaton KE, Wiehe KJ, Vandergrift N, Von Holle TA, Trama AM, Parks RJ, Luo K, Gurley TC, Kepler TB, Marshall DJ, Montefiori DC, Sutherland LL, Alam MS, Whitesides JF, Bowman CM, Permar SR, Graham BS, Mascola JR, Seed PC, Van Rompay KKA, Tomaras GD, Moody MA, Haynes BF.

J Virol. 2017 Oct 13;91(21). pii: e00923-17. doi: 10.1128/JVI.00923-17. Print 2017 Nov 1.

41.

Preexisting antibodies can protect against congenital cytomegalovirus infection in monkeys.

Nelson CS, Cruz DV, Tran D, Bialas KM, Stamper L, Wu H, Gilbert M, Blair R, Alvarez X, Itell H, Chen M, Deshpande A, Chiuppesi F, Wussow F, Diamond DJ, Vandergrift N, Walter MR, Barry PA, Cohen-Wolkowiez M, Koelle K, Kaur A, Permar SR.

JCI Insight. 2017 Jul 6;2(13). pii: 94002. doi: 10.1172/jci.insight.94002. eCollection 2017 Jul 6.

42.

Maternal Humoral Immune Correlates of Peripartum Transmission of Clade C HIV-1 in the Setting of Peripartum Antiretrovirals.

Mutucumarana CP, Eudailey J, McGuire EP, Vandergrift N, Tegha G, Chasela C, Ellington S, van der Horst C, Kourtis AP, Permar SR, Fouda GG.

Clin Vaccine Immunol. 2017 Aug 4;24(8). pii: e00062-17. doi: 10.1128/CVI.00062-17. Print 2017 Aug.

43.

Highly efficient maternal-fetal Zika virus transmission in pregnant rhesus macaques.

Nguyen SM, Antony KM, Dudley DM, Kohn S, Simmons HA, Wolfe B, Salamat MS, Teixeira LBC, Wiepz GJ, Thoong TH, Aliota MT, Weiler AM, Barry GL, Weisgrau KL, Vosler LJ, Mohns MS, Breitbach ME, Stewart LM, Rasheed MN, Newman CM, Graham ME, Wieben OE, Turski PA, Johnson KM, Post J, Hayes JM, Schultz-Darken N, Schotzko ML, Eudailey JA, Permar SR, Rakasz EG, Mohr EL, Capuano S 3rd, Tarantal AF, Osorio JE, O'Connor SL, Friedrich TC, O'Connor DH, Golos TG.

PLoS Pathog. 2017 May 25;13(5):e1006378. doi: 10.1371/journal.ppat.1006378. eCollection 2017 May.

44.

Maternal immune correlates of protection against placental transmission of cytomegalovirus.

Itell HL, Nelson CS, Martinez DR, Permar SR.

Placenta. 2017 Dec;60 Suppl 1:S73-S79. doi: 10.1016/j.placenta.2017.04.011. Epub 2017 Apr 20. Review.

45.

Plasmablast Response to Primary Rhesus Cytomegalovirus (CMV) Infection in a Monkey Model of Congenital CMV Transmission.

Fan Q, Nelson CS, Bialas KM, Chiuppesi F, Amos J, Gurley TC, Marshall DJ, Eudailey J, Heimsath H, Himes J, Deshpande A, Walter MR, Wussow F, Diamond DJ, Barry PA, Moody MA, Kaur A, Permar SR.

Clin Vaccine Immunol. 2017 May 5;24(5). pii: e00510-16. doi: 10.1128/CVI.00510-16. Print 2017 May.

46.

Maternal Binding and Neutralizing IgG Responses Targeting the C-Terminal Region of the V3 Loop Are Predictive of Reduced Peripartum HIV-1 Transmission Risk.

Martinez DR, Vandergrift N, Douglas AO, McGuire E, Bainbridge J, Nicely NI, Montefiori DC, Tomaras GD, Fouda GG, Permar SR.

J Virol. 2017 Apr 13;91(9). pii: e02422-16. doi: 10.1128/JVI.02422-16. Print 2017 May 1.

47.

Geographic Disparities in Cytomegalovirus Infection During Pregnancy.

Lantos PM, Hoffman K, Permar SR, Jackson P, Hughes BL, Swamy GK.

J Pediatric Infect Dis Soc. 2017 Sep 1;6(3):e55-e61. doi: 10.1093/jpids/piw088.

48.

The Impact of the Gut Microbiota on Humoral Immunity to Pathogens and Vaccination in Early Infancy.

Nguyen QN, Himes JE, Martinez DR, Permar SR.

PLoS Pathog. 2016 Dec 22;12(12):e1005997. doi: 10.1371/journal.ppat.1005997. eCollection 2016 Dec. Review. No abstract available.

49.

Maternal Antibody Responses and Nonprimary Congenital Cytomegalovirus Infection of HIV-1-Exposed Infants.

Bialas KM, Westreich D, Cisneros de la Rosa E, Nelson CS, Kauvar LM, Fu TM, Permar SR.

J Infect Dis. 2016 Dec 15;214(12):1916-1923. Epub 2016 Oct 20.

50.

Heterologous Protection against Asian Zika Virus Challenge in Rhesus Macaques.

Aliota MT, Dudley DM, Newman CM, Mohr EL, Gellerup DD, Breitbach ME, Buechler CR, Rasheed MN, Mohns MS, Weiler AM, Barry GL, Weisgrau KL, Eudailey JA, Rakasz EG, Vosler LJ, Post J, Capuano S 3rd, Golos TG, Permar SR, Osorio JE, Friedrich TC, O'Connor SL, O'Connor DH.

PLoS Negl Trop Dis. 2016 Dec 2;10(12):e0005168. doi: 10.1371/journal.pntd.0005168. eCollection 2016 Dec.

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