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Items: 14

1.

Selective Time- and NADPH-Dependent Inhibition of Human CYP2E1 by Clomethiazole.

Stresser DM, Perloff ES, Mason AK, Blanchard AP, Dehal SS, Creegan TP, Singh R, Gangl ET.

Drug Metab Dispos. 2016 Aug;44(8):1424-30. doi: 10.1124/dmd.116.070193. Epub 2016 May 5.

PMID:
27149898
2.

Application of receiver operating characteristic analysis to refine the prediction of potential digoxin drug interactions.

Ellens H, Deng S, Coleman J, Bentz J, Taub ME, Ragueneau-Majlessi I, Chung SP, Herédi-Szabó K, Neuhoff S, Palm J, Balimane P, Zhang L, Jamei M, Hanna I, O'Connor M, Bednarczyk D, Forsgard M, Chu X, Funk C, Guo A, Hillgren KM, Li L, Pak AY, Perloff ES, Rajaraman G, Salphati L, Taur JS, Weitz D, Wortelboer HM, Xia CQ, Xiao G, Yamagata T, Lee CA.

Drug Metab Dispos. 2013 Jul;41(7):1367-74. doi: 10.1124/dmd.112.050542. Epub 2013 Apr 25.

3.

Variability in P-glycoprotein inhibitory potency (IC₅₀) using various in vitro experimental systems: implications for universal digoxin drug-drug interaction risk assessment decision criteria.

Bentz J, O'Connor MP, Bednarczyk D, Coleman J, Lee C, Palm J, Pak YA, Perloff ES, Reyner E, Balimane P, Brännström M, Chu X, Funk C, Guo A, Hanna I, Herédi-Szabó K, Hillgren K, Li L, Hollnack-Pusch E, Jamei M, Lin X, Mason AK, Neuhoff S, Patel A, Podila L, Plise E, Rajaraman G, Salphati L, Sands E, Taub ME, Taur JS, Weitz D, Wortelboer HM, Xia CQ, Xiao G, Yabut J, Yamagata T, Zhang L, Ellens H.

Drug Metab Dispos. 2013 Jul;41(7):1347-66. doi: 10.1124/dmd.112.050500. Epub 2013 Apr 25.

4.

Loxapine P-glycoprotein interactions in vitro.

Reed A, Huie K, Perloff ES, Cassella JV, Takahashi LH.

Drug Metab Lett. 2012 Mar;6(1):26-32.

PMID:
22300294
5.

Validation of cytochrome P450 time-dependent inhibition assays: a two-time point IC50 shift approach facilitates kinact assay design.

Perloff ES, Mason AK, Dehal SS, Blanchard AP, Morgan L, Ho T, Dandeneau A, Crocker RM, Chandler CM, Boily N, Crespi CL, Stresser DM.

Xenobiotica. 2009 Feb;39(2):99-112. doi: 10.1080/00498250802638155.

PMID:
19255936
6.

Differential time- and NADPH-dependent inhibition of CYP2C19 by enantiomers of fluoxetine.

Stresser DM, Mason AK, Perloff ES, Ho T, Crespi CL, Dandeneau AA, Morgan L, Dehal SS.

Drug Metab Dispos. 2009 Apr;37(4):695-8. doi: 10.1124/dmd.108.025726. Epub 2009 Jan 14.

PMID:
19144769
7.

Comparison of duloxetine, escitalopram, and sertraline effects on cytochrome P450 2D6 function in healthy volunteers.

Preskorn SH, Greenblatt DJ, Flockhart D, Luo Y, Perloff ES, Harmatz JS, Baker B, Klick-Davis A, Desta Z, Burt T.

J Clin Psychopharmacol. 2007 Feb;27(1):28-34.

PMID:
17224709
8.

Ginkgo biloba does not alter clearance of flurbiprofen, a cytochrome P450-2C9 substrate.

Greenblatt DJ, von Moltke LL, Luo Y, Perloff ES, Horan KA, Bruce A, Reynolds RC, Harmatz JS, Avula B, Khan IA, Goldman P.

J Clin Pharmacol. 2006 Feb;46(2):214-21.

PMID:
16432273
9.

Interaction of flurbiprofen with cranberry juice, grape juice, tea, and fluconazole: in vitro and clinical studies.

Greenblatt DJ, von Moltke LL, Perloff ES, Luo Y, Harmatz JS, Zinny MA.

Clin Pharmacol Ther. 2006 Jan;79(1):125-33.

PMID:
16413247
10.

Atazanavir: effects on P-glycoprotein transport and CYP3A metabolism in vitro.

Perloff ES, Duan SX, Skolnik PR, Greenblatt DJ, von Moltke LL.

Drug Metab Dispos. 2005 Jun;33(6):764-70. Epub 2005 Mar 11.

PMID:
15764714
11.

MDR1 haplotypes derived from exons 21 and 26 do not affect the steady-state pharmacokinetics of tacrolimus in renal transplant patients.

Mai I, Perloff ES, Bauer S, Goldammer M, Johne A, Filler G, Budde K, Roots I.

Br J Clin Pharmacol. 2004 Nov;58(5):548-53.

12.

Hyperforin content determines the magnitude of the St John's wort-cyclosporine drug interaction.

Mai I, Bauer S, Perloff ES, Johne A, Uehleke B, Frank B, Budde K, Roots I.

Clin Pharmacol Ther. 2004 Oct;76(4):330-40.

PMID:
15470332
13.

Impact of cytochrome P-450 inhibition by cimetidine and induction by carbamazepine on the kinetics of hypericin and pseudohypericin in healthy volunteers.

Johne A, Perloff ES, Bauer S, Schmider J, Mai I, Brockmöller J, Roots I.

Eur J Clin Pharmacol. 2004 Nov;60(9):617-22. Epub 2004 Sep 15.

PMID:
15372129
14.

Analysis of generic antiretroviral formulations manufactured in India.

Ramachandran G, Perloff ES, von Moltke LL, Swaminathan S, Wanke CA, Greenblatt DJ.

AIDS. 2004 Jul 2;18(10):1482-4. No abstract available.

PMID:
15199331

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