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Items: 1 to 50 of 71

1.

Targeting P-selectin Adhesion Molecule in Molecular Imaging: P-selectin Expression as Valuable Imaging Biomarker of Inflammation in Cardiovascular Disease.

Perkins LA, Anderson CJ, Novelli EM.

J Nucl Med. 2019 Oct 10. pii: jnumed.118.225169. doi: 10.2967/jnumed.118.225169. [Epub ahead of print]

PMID:
31601694
2.

High-Content Surface and Total Expression siRNA Kinase Library Screen with VX-809 Treatment Reveals Kinase Targets that Enhance F508del-CFTR Rescue.

Perkins LA, Fisher GW, Naganbabu M, Schmidt BF, Mun F, Bruchez MP.

Mol Pharm. 2018 Mar 5;15(3):759-767. doi: 10.1021/acs.molpharmaceut.7b00928. Epub 2018 Feb 9.

3.

Genetically Targeted Ratiometric and Activated pH Indicator Complexes (TRApHIC) for Receptor Trafficking.

Perkins LA, Yan Q, Schmidt BF, Kolodieznyi D, Saurabh S, Larsen MB, Watkins SC, Kremer L, Bruchez MP.

Biochemistry. 2018 Feb 6;57(5):861-871. doi: 10.1021/acs.biochem.7b01135. Epub 2018 Jan 16.

PMID:
29283245
4.

Multiexcitation Fluorogenic Labeling of Surface, Intracellular, and Total Protein Pools in Living Cells.

Naganbabu M, Perkins LA, Wang Y, Kurish J, Schmidt BF, Bruchez MP.

Bioconjug Chem. 2016 Jun 15;27(6):1525-31. doi: 10.1021/acs.bioconjchem.6b00169. Epub 2016 May 19.

5.

Disseminated Aspergillosis Following Treatment with Corticosteroids in a Patient with Autoimmune Hemolytic Anemia.

Perkins LA, Jones SF, Hays ER.

J S C Med Assoc. 2015 Jun;111(2):56-8. No abstract available.

PMID:
27132332
6.

A genetically targetable near-infrared photosensitizer.

He J, Wang Y, Missinato MA, Onuoha E, Perkins LA, Watkins SC, St Croix CM, Tsang M, Bruchez MP.

Nat Methods. 2016 Mar;13(3):263-8. doi: 10.1038/nmeth.3735. Epub 2016 Jan 25.

7.

Stable Force Balance between Epithelial Cells Arises from F-Actin Turnover.

Jodoin JN, Coravos JS, Chanet S, Vasquez CG, Tworoger M, Kingston ER, Perkins LA, Perrimon N, Martin AC.

Dev Cell. 2015 Dec 21;35(6):685-97. doi: 10.1016/j.devcel.2015.11.018. Epub 2015 Dec 10.

8.

Bio-Environment-Induced Degradation and Failure of Internal Fixation Implants.

Zhou Y, Perkins LA, Wang G, Zhou D, Liang H.

J Funct Biomater. 2015 Oct 15;6(4):1012-20. doi: 10.3390/jfb6041012.

9.

The Transgenic RNAi Project at Harvard Medical School: Resources and Validation.

Perkins LA, Holderbaum L, Tao R, Hu Y, Sopko R, McCall K, Yang-Zhou D, Flockhart I, Binari R, Shim HS, Miller A, Housden A, Foos M, Randkelv S, Kelley C, Namgyal P, Villalta C, Liu LP, Jiang X, Huan-Huan Q, Wang X, Fujiyama A, Toyoda A, Ayers K, Blum A, Czech B, Neumuller R, Yan D, Cavallaro A, Hibbard K, Hall D, Cooley L, Hannon GJ, Lehmann R, Parks A, Mohr SE, Ueda R, Kondo S, Ni JQ, Perrimon N.

Genetics. 2015 Nov;201(3):843-52. doi: 10.1534/genetics.115.180208. Epub 2015 Aug 28.

10.

GLAD: an Online Database of Gene List Annotation for Drosophila.

Hu Y, Comjean A, Perkins LA, Perrimon N, Mohr SE.

J Genomics. 2015 Jul 1;3:75-81. doi: 10.7150/jgen.12863. eCollection 2015.

11.

Near-instant surface-selective fluorogenic protein quantification using sulfonated triarylmethane dyes and fluorogen activating proteins.

Yan Q, Schmidt BF, Perkins LA, Naganbabu M, Saurabh S, Andreko SK, Bruchez MP.

Org Biomol Chem. 2015 Feb 21;13(7):2078-86. doi: 10.1039/c4ob02309a.

12.

Combining genetic perturbations and proteomics to examine kinase-phosphatase networks in Drosophila embryos.

Sopko R, Foos M, Vinayagam A, Zhai B, Binari R, Hu Y, Randklev S, Perkins LA, Gygi SP, Perrimon N.

Dev Cell. 2014 Oct 13;31(1):114-27. doi: 10.1016/j.devcel.2014.07.027. Epub 2014 Oct 2.

13.

Dysregulation in microRNA expression in peripheral blood mononuclear cells of sepsis patients is associated with immunopathology.

Zhou J, Chaudhry H, Zhong Y, Ali MM, Perkins LA, Owens WB, Morales JE, McGuire FR, Zumbrun EE, Zhang J, Nagarkatti PS, Nagarkatti M.

Cytokine. 2015 Jan;71(1):89-100. doi: 10.1016/j.cyto.2014.09.003. Epub 2014 Sep 29.

14.

A regulatory network of Drosophila germline stem cell self-renewal.

Yan D, Neumüller RA, Buckner M, Ayers K, Li H, Hu Y, Yang-Zhou D, Pan L, Wang X, Kelley C, Vinayagam A, Binari R, Randklev S, Perkins LA, Xie T, Cooley L, Perrimon N.

Dev Cell. 2014 Feb 24;28(4):459-73. doi: 10.1016/j.devcel.2014.01.020.

15.

Genetic determinants of phosphate response in Drosophila.

Bergwitz C, Wee MJ, Sinha S, Huang J, DeRobertis C, Mensah LB, Cohen J, Friedman A, Kulkarni M, Hu Y, Vinayagam A, Schnall-Levin M, Berger B, Perkins LA, Mohr SE, Perrimon N.

PLoS One. 2013;8(3):e56753. doi: 10.1371/journal.pone.0056753. Epub 2013 Mar 8.

16.

Depleting gene activities in early Drosophila embryos with the "maternal-Gal4-shRNA" system.

Staller MV, Yan D, Randklev S, Bragdon MD, Wunderlich ZB, Tao R, Perkins LA, Depace AH, Perrimon N.

Genetics. 2013 Jan;193(1):51-61. doi: 10.1534/genetics.112.144915. Epub 2012 Oct 26.

17.

Benefits of a combined approach to sampling of renal neoplasms as demonstrated in a series of 351 cases.

Parks GE, Perkins LA, Zagoria RJ, Garvin AJ, Sirintrapun SJ, Geisinger KR.

Am J Surg Pathol. 2011 Jun;35(6):827-35. doi: 10.1097/PAS.0b013e31821920c8.

PMID:
21552112
18.

A genome-scale shRNA resource for transgenic RNAi in Drosophila.

Ni JQ, Zhou R, Czech B, Liu LP, Holderbaum L, Yang-Zhou D, Shim HS, Tao R, Handler D, Karpowicz P, Binari R, Booker M, Brennecke J, Perkins LA, Hannon GJ, Perrimon N.

Nat Methods. 2011 May;8(5):405-7. doi: 10.1038/nmeth.1592. Epub 2011 Apr 3.

19.

Aspiration cytomorphology of fetal adenocarcinoma of the lung.

Geisinger KR, Travis WD, Perkins LA, Zakowski MF.

Am J Clin Pathol. 2010 Dec;134(6):894-902. doi: 10.1309/AJCP4T5SWATQLKTQ.

PMID:
21088152
20.

Aggressive surgical management of patients with Chiari II malformation and brainstem dysfunction.

Rahman M, Perkins LA, Pincus DW.

Pediatr Neurosurg. 2009;45(5):337-44. doi: 10.1159/000257521. Epub 2009 Nov 11.

PMID:
19907196
21.

A Drosophila resource of transgenic RNAi lines for neurogenetics.

Ni JQ, Liu LP, Binari R, Hardy R, Shim HS, Cavallaro A, Booker M, Pfeiffer BD, Markstein M, Wang H, Villalta C, Laverty TR, Perkins LA, Perrimon N.

Genetics. 2009 Aug;182(4):1089-100. doi: 10.1534/genetics.109.103630. Epub 2009 Jun 1.

22.

Dural venous thrombosis following splenectomy in a patient with hereditary spherocytosis.

Perkins LA, Jones SF, Bhargava RS.

South Med J. 2009 May;102(5):542-5. doi: 10.1097/SMJ.0b013e31819e90b5.

PMID:
19373154
23.

A prospective feasibility trial to determine the significance of the sentinel node gradient in breast cancer: a predictor of nodal metastasis location.

Bleicher RJ, O'Sullivan MJ, Ciocca V, Ciocca RM, Perkins LA, Ross E, Li T, Patchefsky AS, Sigurdson ER, Joseph NE, Sesa L, Morrow M.

Cancer. 2008 Dec 1;113(11):3100-7. doi: 10.1002/cncr.23932.

24.
25.

Nuclear localization of the ERK MAP kinase mediated by Drosophila alphaPS2betaPS integrin and importin-7.

James BP, Bunch TA, Krishnamoorthy S, Perkins LA, Brower DL.

Mol Biol Cell. 2007 Oct;18(10):4190-9. Epub 2007 Aug 15.

26.

Recurring translocation (10;17) and deletion (14q) in clear cell sarcoma of the kidney.

Brownlee NA, Perkins LA, Stewart W, Jackle B, Pettenati MJ, Koty PP, Iskandar SS, Garvin AJ.

Arch Pathol Lab Med. 2007 Mar;131(3):446-51.

PMID:
17516747
27.

Parental factors impacting the enrollment of children in cardiac critical care clinical trials.

Hoffman TM, Taeed R, Niles JP, McMillin MA, Perkins LA, Feltes TF.

Pediatr Cardiol. 2007 May-Jun;28(3):167-71. Epub 2007 Mar 5.

PMID:
17505864
28.

Controlled clinical trial of dichloroacetate for treatment of congenital lactic acidosis in children.

Stacpoole PW, Kerr DS, Barnes C, Bunch ST, Carney PR, Fennell EM, Felitsyn NM, Gilmore RL, Greer M, Henderson GN, Hutson AD, Neiberger RE, O'Brien RG, Perkins LA, Quisling RG, Shroads AL, Shuster JJ, Silverstein JH, Theriaque DW, Valenstein E.

Pediatrics. 2006 May;117(5):1519-31.

PMID:
16651305
29.

smoothened and thickveins regulate Moleskin/Importin 7-mediated MAP kinase signaling in the developing Drosophila eye.

Vrailas AD, Marenda DR, Cook SE, Powers MA, Lorenzen JA, Perkins LA, Moses K.

Development. 2006 Apr;133(8):1485-94. Epub 2006 Mar 15.

30.

Peripheral neuropathy in genetic mitochondrial diseases.

Stickler DE, Valenstein E, Neiberger RE, Perkins LA, Carney PR, Shuster JJ, Theriaque DW, Stacpoole PW.

Pediatr Neurol. 2006 Feb;34(2):127-31.

PMID:
16458825
31.

Transgenic Drosophila models of Noonan syndrome causing PTPN11 gain-of-function mutations.

Oishi K, Gaengel K, Krishnamoorthy S, Kamiya K, Kim IK, Ying H, Weber U, Perkins LA, Tartaglia M, Mlodzik M, Pick L, Gelb BD.

Hum Mol Genet. 2006 Feb 15;15(4):543-53. Epub 2006 Jan 6.

PMID:
16399795
32.

Endoscopic-assisted repair of craniosynostosis.

Murad GJ, Clayman M, Seagle MB, White S, Perkins LA, Pincus DW.

Neurosurg Focus. 2005 Dec 15;19(6):E6.

PMID:
16398483
33.

MAP kinase subcellular localization controls both pattern and proliferation in the developing Drosophila wing.

Marenda DR, Vrailas AD, Rodrigues AB, Cook S, Powers MA, Lorenzen JA, Perkins LA, Moses K.

Development. 2006 Jan;133(1):43-51. Epub 2005 Nov 24.

34.

Dichloroacetate therapy attenuates the blood lactate response to submaximal exercise in patients with defects in mitochondrial energy metabolism.

Duncan GE, Perkins LA, Theriaque DW, Neiberger RE, Stacpoole PW.

J Clin Endocrinol Metab. 2004 Apr;89(4):1733-8.

PMID:
15070938
35.

The Drosophila melanogaster toll pathway participates in resistance to infection by the gram-negative human pathogen Pseudomonas aeruginosa.

Lau GW, Goumnerov BC, Walendziewicz CL, Hewitson J, Xiao W, Mahajan-Miklos S, Tompkins RG, Perkins LA, Rahme LG.

Infect Immun. 2003 Jul;71(7):4059-66.

36.

Genetic interaction between integrins and moleskin, a gene encoding a Drosophila homolog of importin-7.

Baker SE, Lorenzen JA, Miller SW, Bunch TA, Jannuzi AL, Ginsberg MH, Perkins LA, Brower DL.

Genetics. 2002 Sep;162(1):285-96.

37.

Renal manifestations of congenital lactic acidosis.

Neiberger RE, George JC, Perkins LA, Theriaque DW, Hutson AD, Stacpoole PW.

Am J Kidney Dis. 2002 Jan;39(1):12-23.

PMID:
11774096
38.
39.

Doublesex surprises.

Vincent S, Perkins LA, Perrimon N.

Cell. 2001 Aug 24;106(4):399-402. Review. No abstract available.

40.

Nuclear import of activated D-ERK by DIM-7, an importin family member encoded by the gene moleskin.

Lorenzen JA, Baker SE, Denhez F, Melnick MB, Brower DL, Perkins LA.

Development. 2001 Apr;128(8):1403-14.

41.
42.

Interpreting the ins and outs of pulmonary function tests.

Shortall SP, Perkins LA.

Nursing. 1999 Dec;29(12):41-6; quiz 47. No abstract available.

PMID:
10797694
43.

Ventilation without intubation.

Perkins LA, Shortall SP.

RN. 2000 Jan;63(1):34-8; quiz 39. No abstract available.

PMID:
10661312
44.
45.

The importance of cerebrospinal fluid lactate in the evaluation of congenital lactic acidosis.

Stacpoole PW, Bunch ST, Neiberger RE, Perkins LA, Quisling R, Hutson AD, Greer M.

J Pediatr. 1999 Jan;134(1):99-102.

PMID:
9880457
46.

There must be 50 ways to rule the signal: the case of the Drosophila EGF receptor.

Perrimon N, Perkins LA.

Cell. 1997 Apr 4;89(1):13-6. Review. No abstract available.

47.
48.
49.

Dissection of the Torso signal transduction pathway in Drosophila.

Perrimon N, Lu X, Hou XS, Hsu JC, Melnick MB, Chou TB, Perkins LA.

Mol Reprod Dev. 1995 Dec;42(4):515-22. Review.

PMID:
8607984

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