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Agreement of stall-side and laboratory major crossmatch tests with the reference standard method in horses.

Fenn MS, Bortsie-Aryee AD, Perkins GA, Mann S, Tomlinson JE, Wood EM, Mix SE, Stokol T.

J Vet Intern Med. 2020 Feb 4. doi: 10.1111/jvim.15710. [Epub ahead of print]


Cardiac ischemia-reperfusion injury induces ROS-dependent loss of PKA regulatory subunit RIα.

Haushalter KJ, Schilling JM, Song Y, Sastri M, Perkins GA, Strack S, Taylor SS, Patel HH.

Am J Physiol Heart Circ Physiol. 2019 Dec 1;317(6):H1231-H1242. doi: 10.1152/ajpheart.00237.2019. Epub 2019 Nov 1.


An Equine Herpesvirus Type 1 (EHV-1) Ab4 Open Reading Frame 2 Deletion Mutant Provides Immunity and Protection from EHV-1 Infection and Disease.

Schnabel CL, Babasyan S, Rollins A, Freer H, Wimer CL, Perkins GA, Raza F, Osterrieder N, Wagner B.

J Virol. 2019 Oct 29;93(22). pii: e01011-19. doi: 10.1128/JVI.01011-19. Print 2019 Nov 15.


Adipocyte lipolysis affects Perilipin 5 and cristae organization at the cardiac lipid droplet-mitochondrial interface.

Varghese M, Kimler VA, Ghazi FR, Rathore GK, Perkins GA, Ellisman MH, Granneman JG.

Sci Rep. 2019 Mar 18;9(1):4734. doi: 10.1038/s41598-019-41329-4.


Optineurin E50K triggers BDNF deficiency-mediated mitochondrial dysfunction in retinal photoreceptor cell line.

Shim MS, Kim KY, Noh M, Ko JY, Ahn S, An MA, Iwata T, Perkins GA, Weinreb RN, Ju WK.

Biochem Biophys Res Commun. 2018 Sep 18;503(4):2690-2697. doi: 10.1016/j.bbrc.2018.08.025. Epub 2018 Aug 9.


AKAP1 Protects from Cerebral Ischemic Stroke by Inhibiting Drp1-Dependent Mitochondrial Fission.

Flippo KH, Gnanasekaran A, Perkins GA, Ajmal A, Merrill RA, Dickey AS, Taylor SS, McKnight GS, Chauhan AK, Usachev YM, Strack S.

J Neurosci. 2018 Sep 19;38(38):8233-8242. doi: 10.1523/JNEUROSCI.0649-18.2018. Epub 2018 Aug 9.


Aerobic Exercise Preconception and During Pregnancy Enhances Oxidative Capacity in the Hindlimb Muscles of Mice Offspring.

Liu J, Lee I, Feng HZ, Galen SS, Hüttemann PP, Perkins GA, Jin JP, Hüttemann M, Malek MH.

J Strength Cond Res. 2018 May;32(5):1391-1403. doi: 10.1519/JSC.0000000000002416.


First demonstration of equid gammaherpesviruses within the gastric mucosal epithelium of horses.

Pennington MR, Cossic BGA, Perkins GA, Duffy C, Duhamel GE, Van de Walle GR.

Virus Res. 2017 Oct 15;242:30-36. doi: 10.1016/j.virusres.2017.09.002. Epub 2017 Sep 18.


Detection of Salmonella spp. in veterinary samples by combining selective enrichment and real-time PCR.

Goodman LB, McDonough PL, Anderson RR, Franklin-Guild RJ, Ryan JR, Perkins GA, Thachil AJ, Glaser AL, Thompson BS.

J Vet Diagn Invest. 2017 Nov;29(6):844-851. doi: 10.1177/1040638717728315. Epub 2017 Sep 1.


Hematologic, Biochemical, and Endocrine Parameters in Horses With Tooth Resorption and Hypercementosis.

Earley ET, Rawlinson JR, Baratt RM, Galloway SS, Smedley RC, Scarlett JM, Refsal KR, Dotzel AR, Cox VS, Perkins GA.

J Vet Dent. 2017 Sep;34(3):155-160. doi: 10.1177/0898756417717039.


Sub-mitochondrial localization of the genetic-tagged mitochondrial intermembrane space-bridging components Mic19, Mic60 and Sam50.

Sastri M, Darshi M, Mackey M, Ramachandra R, Ju S, Phan S, Adams S, Stein K, Douglas CR, Kim JJ, Ellisman MH, Taylor SS, Perkins GA.

J Cell Sci. 2017 Oct 1;130(19):3248-3260. doi: 10.1242/jcs.201400. Epub 2017 Aug 14.


Pink1 and Parkin regulate Drosophila intestinal stem cell proliferation during stress and aging.

Koehler CL, Perkins GA, Ellisman MH, Jones DL.

J Cell Biol. 2017 Aug 7;216(8):2315-2327. doi: 10.1083/jcb.201610036. Epub 2017 Jun 29.


Hypoxia-inducible factor-1α activation improves renal oxygenation and mitochondrial function in early chronic kidney disease.

Thomas JL, Pham H, Li Y, Hall E, Perkins GA, Ali SS, Patel HH, Singh P.

Am J Physiol Renal Physiol. 2017 Aug 1;313(2):F282-F290. doi: 10.1152/ajprenal.00579.2016. Epub 2017 Mar 22.


Corrigendum: Mitochondrial pathogenic mechanism and degradation in optineurin E50K mutation-mediated retinal ganglion cell degeneration.

Shim MS, Takihara Y, Kim KY, Iwata T, Yue BY, Inatani M, Weinreb RN, Perkins GA, Ju WK.

Sci Rep. 2017 Jan 19;7:40460. doi: 10.1038/srep40460. No abstract available.


Proteolipid protein-deficient myelin promotes axonal mitochondrial dysfunction via altered metabolic coupling.

Yin X, Kidd GJ, Ohno N, Perkins GA, Ellisman MH, Bastian C, Brunet S, Baltan S, Trapp BD.

J Cell Biol. 2016 Nov 21;215(4):531-542.


Mitochondrial pathogenic mechanism and degradation in optineurin E50K mutation-mediated retinal ganglion cell degeneration.

Shim MS, Takihara Y, Kim KY, Iwata T, Yue BY, Inatani M, Weinreb RN, Perkins GA, Ju WK.

Sci Rep. 2016 Sep 22;6:33830. doi: 10.1038/srep33830. Erratum in: Sci Rep. 2017 Jan 19;7:40460.


Antimicrobial resistance trends among Salmonella isolates obtained from horses in the northeastern United States (2001-2013).

Cummings KJ, Perkins GA, Khatibzadeh SM, Warnick LD, Aprea VA, Altier C.

Am J Vet Res. 2016 May;77(5):505-13. doi: 10.2460/ajvr.77.5.505.


Erratum to: Impact of Chromogranin A deficiency on catecholamine storage, catecholamine granule morphology and chromaffin cell energy metabolism in vivo.

Pasqua T, Mahata S, Bandyopadhyay GK, Biswas A, Perkins GA, Sinha-Hikim AP, Goldstein DS, Eiden LE, Mahata SK.

Cell Tissue Res. 2016 Mar;363(3):823. doi: 10.1007/s00441-016-2362-5. No abstract available.


Impact of Chromogranin A deficiency on catecholamine storage, catecholamine granule morphology and chromaffin cell energy metabolism in vivo.

Pasqua T, Mahata S, Bandyopadhyay GK, Biswas A, Perkins GA, Sinha-Hikim AP, Goldstein DS, Eiden LE, Mahata SK.

Cell Tissue Res. 2016 Mar;363(3):693-712. doi: 10.1007/s00441-015-2316-3. Epub 2015 Nov 16. Erratum in: Cell Tissue Res. 2016 Mar;363(3):823.


Antibody and cellular immune responses of naïve mares to repeated vaccination with an inactivated equine herpesvirus vaccine.

Wagner B, Goodman LB, Babasyan S, Freer H, Torsteinsdóttir S, Svansson V, Björnsdóttir S, Perkins GA.

Vaccine. 2015 Oct 13;33(42):5588-5597. doi: 10.1016/j.vaccine.2015.09.009. Epub 2015 Sep 16.


ECG of the Month. Persistent atrial tachycardia after cardioversion in a horse.

Barrell EA, Fiorenza LR, Perkins GA, Kraus MS.

J Am Vet Med Assoc. 2015 Oct 1;247(7):751-3. doi: 10.2460/javma.247.7.751. No abstract available.


DRP1 inhibition rescues retinal ganglion cells and their axons by preserving mitochondrial integrity in a mouse model of glaucoma.

Kim KY, Perkins GA, Shim MS, Bushong E, Alcasid N, Ju S, Ellisman MH, Weinreb RN, Ju WK.

Cell Death Dis. 2015 Aug 6;6:e1839. doi: 10.1038/cddis.2015.180.


Resolving presynaptic structure by electron tomography.

Perkins GA, Jackson DR, Spirou GA.

Synapse. 2015 May;69(5):268-82. doi: 10.1002/syn.21813. Epub 2015 Mar 9. Review.


Increased mitochondrial fission and volume density by blocking glutamate excitotoxicity protect glaucomatous optic nerve head astrocytes.

Ju WK, Kim KY, Noh YH, Hoshijima M, Lukas TJ, Ellisman MH, Weinreb RN, Perkins GA.

Glia. 2015 May;63(5):736-53. doi: 10.1002/glia.22781. Epub 2014 Dec 31.


West Nile virus-specific immunoglobulin isotype responses in vaccinated and infected horses.

Khatibzadeh SM, Gold CB, Keggan AE, Perkins GA, Glaser AL, Dubovi EJ, Wagner B.

Am J Vet Res. 2015 Jan;76(1):92-100. doi: 10.2460/ajvr.76.1.92.


The use of miniSOG in the localization of mitochondrial proteins.

Perkins GA.

Methods Enzymol. 2014;547:165-79. doi: 10.1016/B978-0-12-801415-8.00010-2.


The development of equine immunity: Current knowledge on immunology in the young horse.

Perkins GA, Wagner B.

Equine Vet J. 2015 May;47(3):267-74. doi: 10.1111/evj.12387. Epub 2015 Jan 6. Review.


Maternal T-lymphocytes in equine colostrum express a primarily inflammatory phenotype.

Perkins GA, Goodman LB, Wimer C, Freer H, Babasyan S, Wagner B.

Vet Immunol Immunopathol. 2014 Oct 15;161(3-4):141-50. doi: 10.1016/j.vetimm.2014.07.009. Epub 2014 Aug 2.


Salmonella enterica serovar Oranienburg outbreak in a veterinary medical teaching hospital with evidence of nosocomial and on-farm transmission.

Cummings KJ, Rodriguez-Rivera LD, Mitchell KJ, Hoelzer K, Wiedmann M, McDonough PL, Altier C, Warnick LD, Perkins GA.

Vector Borne Zoonotic Dis. 2014 Jul;14(7):496-502. doi: 10.1089/vbz.2013.1467. Epub 2014 Jun 5.


Inhibition of oxidative stress by coenzyme Q10 increases mitochondrial mass and improves bioenergetic function in optic nerve head astrocytes.

Noh YH, Kim KY, Shim MS, Choi SH, Choi S, Ellisman MH, Weinreb RN, Perkins GA, Ju WK.

Cell Death Dis. 2013 Oct 3;4:e820. doi: 10.1038/cddis.2013.341.


Integrins protect cardiomyocytes from ischemia/reperfusion injury.

Okada H, Lai NC, Kawaraguchi Y, Liao P, Copps J, Sugano Y, Okada-Maeda S, Banerjee I, Schilling JM, Gingras AR, Asfaw EK, Suarez J, Kang SM, Perkins GA, Au CG, Israeli-Rosenberg S, Manso AM, Liu Z, Milner DJ, Kaufman SJ, Patel HH, Roth DM, Hammond HK, Taylor SS, Dillmann WH, Goldhaber JI, Ross RS.

J Clin Invest. 2013 Oct;123(10):4294-308. doi: 10.1172/JCI64216. Epub 2013 Sep 16.


Quantitative proteomic and functional analysis of liver mitochondria from high fat diet (HFD) diabetic mice.

Guo Y, Darshi M, Ma Y, Perkins GA, Shen Z, Haushalter KJ, Saito R, Chen A, Lee YS, Patel HH, Briggs SP, Ellisman MH, Olefsky JM, Taylor SS.

Mol Cell Proteomics. 2013 Dec;12(12):3744-58. doi: 10.1074/mcp.M113.027441. Epub 2013 Sep 12.


DIDS (4,4-diisothiocyanatostilbenedisulphonic acid) induces apoptotic cell death in a hippocampal neuronal cell line and is not neuroprotective against ischemic stress.

Pamenter ME, Perkins GA, Gu XQ, Ellisman MH, Haddad GG.

PLoS One. 2013;8(4):e60804. doi: 10.1371/journal.pone.0060804. Epub 2013 Apr 5.


Antimicrobial resistance trends among Salmonella isolates obtained from dairy cattle in the northeastern United States, 2004-2011.

Cummings KJ, Perkins GA, Khatibzadeh SM, Warnick LD, Altier C.

Foodborne Pathog Dis. 2013 Apr;10(4):353-61. doi: 10.1089/fpd.2012.1285. Epub 2013 Mar 4.


Report of the third Havemeyer workshop on infection control in equine populations.

Morley PS, Anderson ME, Burgess BA, Aceto H, Bender JB, Clark C, Daniels JB, Davis MA, Hinchcliff KW, Johnson JR, McClure J, Perkins GA, Pusterla N, Traub-Dargatz JL, Weese JS, Whittem TL.

Equine Vet J. 2013 Mar;45(2):131-6. doi: 10.1111/evj.12000. No abstract available.


Evaluation of metaphylactic RNA interference to prevent equine herpesvirus type 1 infection in experimental herpesvirus myeloencephalopathy in horses.

Perkins GA, Van de Walle GR, Pusterla N, Erb HN, Osterrieder N.

Am J Vet Res. 2013 Feb;74(2):248-56. doi: 10.2460/ajvr.74.2.248.


Cerebrospinal fluid eosinophilia is a sensitive and specific test for the diagnosis of Parelaphostrongylus tenuis in camelids in the northeastern United States.

Pinn TL, Bender HS, Stokol T, Erb HN, Schlafer DH, Perkins GA.

J Vet Diagn Invest. 2013 Jan;25(1):54-60. doi: 10.1177/1040638712471058.


(-)-Epicatechin is associated with increased angiogenic and mitochondrial signalling in the hindlimb of rats selectively bred for innate low running capacity.

Hüttemann M, Lee I, Perkins GA, Britton SL, Koch LG, Malek MH.

Clin Sci (Lond). 2013 Jun;124(11):663-74. doi: 10.1042/CS20120469.


Autophagy and apoptosis are differentially induced in neurons and astrocytes treated with an in vitro mimic of the ischemic penumbra.

Pamenter ME, Perkins GA, McGinness AK, Gu XQ, Ellisman MH, Haddad GG.

PLoS One. 2012;7(12):e51469. doi: 10.1371/journal.pone.0051469. Epub 2012 Dec 12.


Ceramide and its transport protein (CERT) contribute to deterioration of mitochondrial structure and function in aging oocytes.

Kujjo LL, Acton BM, Perkins GA, Ellisman MH, D'Estaing SG, Casper RF, Jurisicova A, Perez GI.

Mech Ageing Dev. 2013 Jan-Feb;134(1-2):43-52. doi: 10.1016/j.mad.2012.12.001. Epub 2012 Dec 11.


Maintenance of metabolic homeostasis by Sestrin2 and Sestrin3.

Lee JH, Budanov AV, Talukdar S, Park EJ, Park HL, Park HW, Bandyopadhyay G, Li N, Aghajan M, Jang I, Wolfe AM, Perkins GA, Ellisman MH, Bier E, Scadeng M, Foretz M, Viollet B, Olefsky J, Karin M.

Cell Metab. 2012 Sep 5;16(3):311-21. doi: 10.1016/j.cmet.2012.08.004.


DIDS prevents ischemic membrane degradation in cultured hippocampal neurons by inhibiting matrix metalloproteinase release.

Pamenter ME, Ryu J, Hua ST, Perkins GA, Mendiola VL, Gu XQ, Ellisman MH, Haddad GG.

PLoS One. 2012;7(8):e43995. doi: 10.1371/journal.pone.0043995. Epub 2012 Aug 24.


Serum iron parameters and acute experimental EHV-1 infection in horses.

Brosnahan MM, Erb HN, Perkins GA, Divers TJ, Borges AS, Osterrieder N.

J Vet Intern Med. 2012 Sep-Oct;26(5):1232-5. doi: 10.1111/j.1939-1676.2012.00963.x. Epub 2012 Jul 2.


Striated organelle, a cytoskeletal structure positioned to modulate hair-cell transduction.

Vranceanu F, Perkins GA, Terada M, Chidavaenzi RL, Ellisman MH, Lysakowski A.

Proc Natl Acad Sci U S A. 2012 Mar 20;109(12):4473-8. doi: 10.1073/pnas.1101003109. Epub 2012 Mar 6.


Equine stomachs harbor an abundant and diverse mucosal microbiota.

Perkins GA, den Bakker HC, Burton AJ, Erb HN, McDonough SP, McDonough PL, Parker J, Rosenthal RL, Wiedmann M, Dowd SE, Simpson KW.

Appl Environ Microbiol. 2012 Apr;78(8):2522-32. doi: 10.1128/AEM.06252-11. Epub 2012 Feb 3.


A new vicious cycle involving glutamate excitotoxicity, oxidative stress and mitochondrial dynamics.

Nguyen D, Alavi MV, Kim KY, Kang T, Scott RT, Noh YH, Lindsey JD, Wissinger B, Ellisman MH, Weinreb RN, Perkins GA, Ju WK.

Cell Death Dis. 2011 Dec 8;2:e240. doi: 10.1038/cddis.2011.117.


What is your diagnosis? Tracheal stenosis and collapse.

Ollivett TL, Perkins GA, Thompson MS.

J Am Vet Med Assoc. 2011 Sep 15;239(6):747-8. doi: 10.2460/javma.239.6.747. No abstract available.


(-)-Epicatechin enhances fatigue resistance and oxidative capacity in mouse muscle.

Nogueira L, Ramirez-Sanchez I, Perkins GA, Murphy A, Taub PR, Ceballos G, Villarreal FJ, Hogan MC, Malek MH.

J Physiol. 2011 Sep 15;589(Pt 18):4615-31. doi: 10.1113/jphysiol.2011.209924. Epub 2011 Jul 25.


Mitochondrial phosphatase PTPMT1 is essential for cardiolipin biosynthesis.

Zhang J, Guan Z, Murphy AN, Wiley SE, Perkins GA, Worby CA, Engel JL, Heacock P, Nguyen OK, Wang JH, Raetz CR, Dowhan W, Dixon JE.

Cell Metab. 2011 Jun 8;13(6):690-700. doi: 10.1016/j.cmet.2011.04.007.

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