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Items: 1 to 50 of 145

1.

Genetic variation in interleukin-7 is associated with a reduced erythropoietic response in Kenyan children infected with Plasmodium falciparum.

Kisia LE, Kempaiah P, Anyona SB, Munde EO, Achieng AO, Ong'echa JM, Lambert CG, Chelimo K, Ouma C, Perkins DJ, Raballah E.

BMC Med Genet. 2019 Aug 16;20(1):140. doi: 10.1186/s12881-019-0866-z.

2.

Integrated OMICS platforms identify LAIR1 genetic variants as novel predictors of cross-sectional and longitudinal susceptibility to severe malaria and all-cause mortality in Kenyan children.

Achieng AO, Hengartner NW, Raballah E, Cheng Q, Anyona SB, Lauve N, Guyah B, Foo-Hurwitz I, Ong'echa JM, McMahon BH, Ouma C, Lambert CG, Perkins DJ.

EBioMedicine. 2019 Jul;45:290-302. doi: 10.1016/j.ebiom.2019.06.043. Epub 2019 Jul 2.

3.

Molecular basis of reduced LAIR1 expression in childhood severe malarial anaemia: Implications for leukocyte inhibitory signalling.

Achieng AO, Guyah B, Cheng Q, Ong'echa JM, Ouma C, Lambert CG, Perkins DJ.

EBioMedicine. 2019 Jul;45:278-289. doi: 10.1016/j.ebiom.2019.06.040. Epub 2019 Jun 27.

4.

Assessing the Dynamics and Complexity of Disease Pathogenicity Using 4-Dimensional Immunological Data.

Rivas AL, Hoogesteijn AL, Antoniades A, Tomazou M, Buranda T, Perkins DJ, Fair JM, Durvasula R, Fasina FO, Tegos GP, van Regenmortel MHV.

Front Immunol. 2019 Jun 12;10:1258. doi: 10.3389/fimmu.2019.01258. eCollection 2019.

5.

Preferences of Information Dissemination on Treatment for Bipolar Disorder: Patient-Centered Focus Group Study.

Kerner B, Crisanti AS, DeShaw JL, Ho JG, Jordan K, Krall RL, Kuntz MJ, Mazurie AJ, Nestsiarovich A, Perkins DJ, Schroeter QL, Smith AN, Tohen M, Volesky E, Zhu Y, Lambert CG.

JMIR Ment Health. 2019 Jun 25;6(6):e12848. doi: 10.2196/12848.

6.

Evolution and Genetic Diversity of the k13 Gene Associated with Artemisinin Delayed Parasite Clearance in Plasmodium falciparum.

Pacheco MA, Kadakia ER, Chaudhary Z, Perkins DJ, Kelley J, Ravishankar S, Cranfield M, Talundzic E, Udhayakumar V, Escalante AA.

Antimicrob Agents Chemother. 2019 Jul 25;63(8). pii: e02550-18. doi: 10.1128/AAC.02550-18. Print 2019 Aug.

PMID:
31085516
7.

Influenza "Trains" the Host for Enhanced Susceptibility to Secondary Bacterial Infection.

Shirey KA, Perkins DJ, Lai W, Zhang W, Fernando LR, Gusovsky F, Blanco JCG, Vogel SN.

MBio. 2019 May 7;10(3). pii: e00810-19. doi: 10.1128/mBio.00810-19.

8.

Genome Sequences of a Staphylococcus aureus Clinical Isolate, Strain SMA0034-04 (UGA22), from Siaya County Referral Hospital in Siaya, Kenya.

Xie G, Cheng Q, Daligault H, Davenport K, Gleasner C, Jacobs L, Kubicek-Sutherland J, LeCuyer T, Otieno V, Raballah E, Mukundan H, Perkins DJ, McMahon B, Doggett N.

Microbiol Resour Announc. 2019 Apr 25;8(17). pii: e01627-18. doi: 10.1128/MRA.01627-18.

9.

Genome Sequence of Staphylococcus pettenkoferi Strain SMA0010-04 (UGA20), a Clinical Isolate from Siaya County Referral Hospital in Siaya, Kenya.

Otieno V, Xie G, Cheng Q, Daligault H, Davenport K, Gleasner C, Jacobs L, Kubicek-Sutherland J, LeCuyer T, Raballah E, Doggett N, Mukundan H, McMahon B, Perkins DJ.

Microbiol Resour Announc. 2019 Apr 25;8(17). pii: e01626-18. doi: 10.1128/MRA.01626-18.

10.

Genome Sequence of a Staphylococcus xylosus Clinical Isolate, Strain SMA0341-04 (UGA5), from Siaya County Referral Hospital in Siaya, Kenya.

Cheng Q, Xie G, Daligault H, Davenport K, Gleasner C, Jacobs L, Kubicek-Sutherland J, LeCuyer T, Otieno V, Raballah E, Doggett N, McMahon B, Perkins DJ, Mukundan H.

Microbiol Resour Announc. 2019 Apr 18;8(16). pii: e01625-18. doi: 10.1128/MRA.01625-18.

11.

Direct detection of bacteremia by exploiting host-pathogen interactions of lipoteichoic acid and lipopolysaccharide.

Kubicek-Sutherland JZ, Vu DM, Noormohamed A, Mendez HM, Stromberg LR, Pedersen CA, Hengartner AC, Klosterman KE, Bridgewater HA, Otieno V, Cheng Q, Anyona SB, Ouma C, Raballah E, Perkins DJ, McMahon BH, Mukundan H.

Sci Rep. 2019 Apr 17;9(1):6203. doi: 10.1038/s41598-019-42502-5.

12.

Comparison of 71 bipolar disorder pharmacotherapies for kidney disorder risk: The potential hazards of polypharmacy.

Nestsiarovich A, Kerner B, Mazurie AJ, Cannon DC, Hurwitz NG, Zhu Y, Nelson SJ, Oprea TI, Unruh ML, Crisanti AS, Tohen M, Perkins DJ, Lambert CG.

J Affect Disord. 2019 Jun 1;252:201-211. doi: 10.1016/j.jad.2019.04.009. Epub 2019 Apr 8.

13.

Draft Genome Sequences of Two Staphylococcus warneri Clinical Isolates, Strains SMA0023-04 (UGA3) and SMA0670-05 (UGA28), from Siaya County Referral Hospital, Siaya, Kenya.

Xie G, Cheng Q, Daligault H, Davenport K, Gleasner C, Jacobs L, Kubicek-Sutherland J, LeCuyer T, Otieno V, Raballah E, Doggett N, Mukundan H, Perkins DJ, McMahon B.

Microbiol Resour Announc. 2019 Apr 11;8(15). pii: e01595-18. doi: 10.1128/MRA.01595-18.

14.

Autocrine-paracrine prostaglandin E2 signaling restricts TLR4 internalization and TRIF signaling.

Perkins DJ, Richard K, Hansen AM, Lai W, Nallar S, Koller B, Vogel SN.

Nat Immunol. 2018 Dec;19(12):1309-1318. doi: 10.1038/s41590-018-0243-7. Epub 2018 Nov 5.

15.

Improved Tolerability of a Salmonella enterica Serovar Typhimurium Live-Attenuated Vaccine Strain Achieved by Balancing Inflammatory Potential with Immunogenicity.

Higginson EE, Ramachandran G, Panda A, Shipley ST, Kriel EH, DeTolla LJ, Lipsky M, Perkins DJ, Salerno-Goncalves R, Sztein MB, Pasetti MF, Levine MM, Tennant SM.

Infect Immun. 2018 Nov 20;86(12). pii: e00440-18. doi: 10.1128/IAI.00440-18. Print 2018 Dec.

16.

Comprehensive comparison of monotherapies for psychiatric hospitalization risk in bipolar disorders.

Nestsiarovich A, Mazurie AJ, Hurwitz NG, Kerner B, Nelson SJ, Crisanti AS, Tohen M, Krall RL, Perkins DJ, Lambert CG.

Bipolar Disord. 2018 Dec;20(8):761-771. doi: 10.1111/bdi.12665. Epub 2018 Jun 19.

17.

Systemic challenges in bipolar disorder management: A patient-centered approach.

Nestsiarovich A, Hurwitz NG, Nelson SJ, Crisanti AS, Kerner B, Kuntz MJ, Smith AN, Volesky E, Schroeter QL, DeShaw JL, Young SS, Obenchain RL, Krall RL, Jordan K, Fawcett J, Tohen M, Perkins DJ, Lambert CG.

Bipolar Disord. 2017 Dec;19(8):676-688. doi: 10.1111/bdi.12547. Epub 2017 Sep 13.

18.

Synergistic blending of high-valued heterocycles inhibits growth of Plasmodium falciparum in culture and P. berghei infection in mouse model.

Kumar P, Achieng AO, Rajendran V, Ghosh PC, Singh BK, Rawat M, Perkins DJ, Kempaiah P, Rathi B.

Sci Rep. 2017 Jul 27;7(1):6724. doi: 10.1038/s41598-017-06097-z.

19.

Association between Fcγ receptor IIA, IIIA and IIIB genetic polymorphisms and susceptibility to severe malaria anemia in children in western Kenya.

Munde EO, Okeyo WA, Raballah E, Anyona SB, Were T, Ong'echa JM, Perkins DJ, Ouma C.

BMC Infect Dis. 2017 Apr 20;17(1):289. doi: 10.1186/s12879-017-2390-0.

20.

Haplotype of non-synonymous mutations within IL-23R is associated with susceptibility to severe malaria anemia in a P. falciparum holoendemic transmission area of Kenya.

Munde EO, Raballah E, Okeyo WA, Ong'echa JM, Perkins DJ, Ouma C.

BMC Infect Dis. 2017 Apr 20;17(1):291. doi: 10.1186/s12879-017-2404-y.

21.

CD4 T-cell expression of IFN-γ and IL-17 in pediatric malarial anemia.

Raballah E, Kempaiah P, Karim Z, Orinda GO, Otieno MF, Perkins DJ, Ong'echa JM.

PLoS One. 2017 Apr 20;12(4):e0175864. doi: 10.1371/journal.pone.0175864. eCollection 2017.

22.

AMP-activated Kinase (AMPK) Promotes Innate Immunity and Antiviral Defense through Modulation of Stimulator of Interferon Genes (STING) Signaling.

Prantner D, Perkins DJ, Vogel SN.

J Biol Chem. 2017 Jan 6;292(1):292-304. doi: 10.1074/jbc.M116.763268. Epub 2016 Nov 22.

23.

Reduced Hsp70 and Glutamine in Pediatric Severe Malaria Anemia: Role of Hemozoin in Suppressing Hsp70 and NF-κB activation.

Kempaiah P, Dokladny K, Karim Z, Raballah E, Ong'echa JM, Moseley PL, Perkins DJ.

Mol Med. 2016 Oct;22:570-584. doi: 10.2119/molmed.2016.00130. Epub 2016 Aug 30.

24.

The Prostaglandin E2-EP3 Receptor Axis Regulates Anaplasma phagocytophilum-Mediated NLRC4 Inflammasome Activation.

Wang X, Shaw DK, Hammond HL, Sutterwala FS, Rayamajhi M, Shirey KA, Perkins DJ, Bonventre JV, Velayutham TS, Evans SM, Rodino KG, VieBrock L, Scanlon KM, Carbonetti NH, Carlyon JA, Miao EA, McBride JW, Kotsyfakis M, Pedra JH.

PLoS Pathog. 2016 Aug 2;12(8):e1005803. doi: 10.1371/journal.ppat.1005803. eCollection 2016 Aug.

25.

Reduced Parasite Burden in Children with Falciparum Malaria and Bacteremia Coinfections: Role of Mediators of Inflammation.

Davenport GC, Hittner JB, Otieno V, Karim Z, Mukundan H, Fenimore PW, Hengartner NW, McMahon BH, Kempaiah P, Ong'echa JM, Perkins DJ.

Mediators Inflamm. 2016;2016:4286576. doi: 10.1155/2016/4286576. Epub 2016 Jun 22.

26.

Epigenetic Mechanisms Governing Innate Inflammatory Responses.

Perkins DJ, Patel MC, Blanco JC, Vogel SN.

J Interferon Cytokine Res. 2016 Jul;36(7):454-61. doi: 10.1089/jir.2016.0003. Review.

27.

Type I interferon licenses enhanced innate recognition and transcriptional responses to Franciscella tularensis live vaccine strain.

Richard K, Vogel SN, Perkins DJ.

Innate Immun. 2016 Jul;22(5):363-72. doi: 10.1177/1753425916650027. Epub 2016 May 26.

28.

Hypothyroidism risk compared among nine common bipolar disorder therapies in a large US cohort.

Lambert CG, Mazurie AJ, Lauve NR, Hurwitz NG, Young SS, Obenchain RL, Hengartner NW, Perkins DJ, Tohen M, Kerner B.

Bipolar Disord. 2016 May;18(3):247-60. doi: 10.1111/bdi.12391.

29.

The Tick Protein Sialostatin L2 Binds to Annexin A2 and Inhibits NLRC4-Mediated Inflammasome Activation.

Wang X, Shaw DK, Sakhon OS, Snyder GA, Sundberg EJ, Santambrogio L, Sutterwala FS, Dumler JS, Shirey KA, Perkins DJ, Richard K, Chagas AC, Calvo E, Kopecký J, Kotsyfakis M, Pedra JHF.

Infect Immun. 2016 May 24;84(6):1796-1805. doi: 10.1128/IAI.01526-15. Print 2016 Jun.

30.

Inflammation: Species-specific TLR signalling -- insight into human disease.

Perkins DJ, Vogel SN.

Nat Rev Rheumatol. 2016 Apr;12(4):198-200. doi: 10.1038/nrrheum.2016.36.

31.

Natural infection of Plasmodium brasilianum in humans: Man and monkey share quartan malaria parasites in the Venezuelan Amazon.

Lalremruata A, Magris M, Vivas-Martínez S, Koehler M, Esen M, Kempaiah P, Jeyaraj S, Perkins DJ, Mordmüller B, Metzger WG.

EBioMedicine. 2015 Jul 29;2(9):1186-92. doi: 10.1016/j.ebiom.2015.07.033. eCollection 2015 Sep.

32.

Salmonella Typhimurium Co-Opts the Host Type I IFN System To Restrict Macrophage Innate Immune Transcriptional Responses Selectively.

Perkins DJ, Rajaiah R, Tennant SM, Ramachandran G, Higginson EE, Dyson TN, Vogel SN.

J Immunol. 2015 Sep 1;195(5):2461-71. doi: 10.4049/jimmunol.1500105. Epub 2015 Jul 22.

33.

CD14 dependence of TLR4 endocytosis and TRIF signaling displays ligand specificity and is dissociable in endotoxin tolerance.

Rajaiah R, Perkins DJ, Ireland DD, Vogel SN.

Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):8391-6. doi: 10.1073/pnas.1424980112. Epub 2015 Jun 23.

34.

Space and time: New considerations about the relationship between Toll-like receptors (TLRs) and type I interferons (IFNs).

Perkins DJ, Vogel SN.

Cytokine. 2015 Aug;74(2):171-4. doi: 10.1016/j.cyto.2015.03.001. Epub 2015 Mar 25. Review.

35.

Invasive Salmonella Typhimurium ST313 with naturally attenuated flagellin elicits reduced inflammation and replicates within macrophages.

Ramachandran G, Perkins DJ, Schmidlein PJ, Tulapurkar ME, Tennant SM.

PLoS Negl Trop Dis. 2015 Jan 8;9(1):e3394. doi: 10.1371/journal.pntd.0003394. eCollection 2015 Jan.

36.

Predictions of x-ray scattering spectra for warm dense matter.

Souza AN, Perkins DJ, Starrett CE, Saumon D, Hansen SB.

Phys Rev E Stat Nonlin Soft Matter Phys. 2014 Feb;89(2):023108. Epub 2014 Feb 24.

PMID:
25353587
37.

The Effects of Plasmodium vivax Gestational Malaria on the Clinical and Immune Status of Pregnant Women in Northwestern Colombia.

Yasnot MF, Perkins DJ, Corredor M, Yanow S, Carmona-Fonseca J, Maestre A.

Colomb Med (Cali). 2013 Sep 30;44(3):172-7. eCollection 2013 Jul.

38.

Efficacy and safety of artemether-lumefantrine and dihydroartemisinin-piperaquine in the treatment of uncomplicated Plasmodium falciparum malaria in Kenyan children aged less than five years: results of an open-label, randomized, single-centre study.

Ogutu BR, Onyango KO, Koskei N, Omondi EK, Ongecha JM, Otieno GA, Obonyo C, Otieno L, Eyase F, Johnson JD, Omollo R, Perkins DJ, Akhwale W, Juma E.

Malar J. 2014 Jan 28;13:33. doi: 10.1186/1475-2875-13-33.

39.

Reprogramming of murine macrophages through TLR2 confers viral resistance via TRAF3-mediated, enhanced interferon production.

Perkins DJ, Polumuri SK, Pennini ME, Lai W, Xie P, Vogel SN.

PLoS Pathog. 2013;9(7):e1003479. doi: 10.1371/journal.ppat.1003479. Epub 2013 Jul 11.

40.

Suppressed circulating bicyclo-PGE2 levels and leukocyte COX-2 transcripts in children co-infected with P. falciparum malaria and HIV-1 or bacteremia.

Anyona SB, Kempaiah P, Davenport GC, Vulule JM, Hittner JB, Ong'echa JM, Perkins DJ.

Biochem Biophys Res Commun. 2013 Jul 12;436(4):585-90. doi: 10.1016/j.bbrc.2013.05.089. Epub 2013 Jun 3.

41.

Dissociation of endotoxin tolerance and differentiation of alternatively activated macrophages.

Rajaiah R, Perkins DJ, Polumuri SK, Zhao A, Keegan AD, Vogel SN.

J Immunol. 2013 May 1;190(9):4763-72. doi: 10.4049/jimmunol.1202407. Epub 2013 Mar 29.

42.

Interleukin (IL)-13 promoter polymorphisms (-7402 T/G and -4729G/A) condition susceptibility to pediatric severe malarial anemia but not circulating IL-13 levels.

Okeyo WA, Munde EO, Okumu W, Raballah E, Anyona SB, Vulule JM, Ong'echa JM, Perkins DJ, Ouma C.

BMC Immunol. 2013 Mar 25;14:15. doi: 10.1186/1471-2172-14-15.

43.

Feedback-based, system-level properties of vertebrate-microbial interactions.

Rivas AL, Jankowski MD, Piccinini R, Leitner G, Schwarz D, Anderson KL, Fair JM, Hoogesteijn AL, Wolter W, Chaffer M, Blum S, Were T, Konah SN, Kempaiah P, Ong'echa JM, Diesterbeck US, Pilla R, Czerny CP, Hittner JB, Hyman JM, Perkins DJ.

PLoS One. 2013;8(2):e53984. doi: 10.1371/journal.pone.0053984. Epub 2013 Feb 20.

44.

Cystic fibrosis CFBE41o- cells contain TLR1 SNP I602S and fail to respond to Mycobacterium abscessus.

Kempaiah P, Davidson LB, Perkins DJ, Byrd TF.

J Cyst Fibros. 2013 Dec;12(6):773-9. doi: 10.1016/j.jcf.2013.01.001. Epub 2013 Feb 9.

45.
46.

5,6-Dimethylxanthenone-4-acetic acid (DMXAA) activates stimulator of interferon gene (STING)-dependent innate immune pathways and is regulated by mitochondrial membrane potential.

Prantner D, Perkins DJ, Lai W, Williams MS, Sharma S, Fitzgerald KA, Vogel SN.

J Biol Chem. 2012 Nov 16;287(47):39776-88. doi: 10.1074/jbc.M112.382986. Epub 2012 Oct 1.

47.

Connecting network properties of rapidly disseminating epizoonotics.

Rivas AL, Fasina FO, Hoogesteyn AL, Konah SN, Febles JL, Perkins DJ, Hyman JM, Fair JM, Hittner JB, Smith SD.

PLoS One. 2012;7(6):e39778. doi: 10.1371/journal.pone.0039778. Epub 2012 Jun 25.

48.

Reduced systemic bicyclo-prostaglandin-E2 and cyclooxygenase-2 gene expression are associated with inefficient erythropoiesis and enhanced uptake of monocytic hemozoin in children with severe malarial anemia.

Anyona SB, Kempaiah P, Raballah E, Davenport GC, Were T, Konah SN, Vulule JM, Hittner JB, Gichuki CW, Ong'echa JM, Perkins DJ.

Am J Hematol. 2012 Aug;87(8):782-9. doi: 10.1002/ajh.23253. Epub 2012 Jun 23.

49.

Transcriptional regulation of murine IL-33 by TLR and non-TLR agonists.

Polumuri SK, Jayakar GG, Shirey KA, Roberts ZJ, Perkins DJ, Pitha PM, Vogel SN.

J Immunol. 2012 Jul 1;189(1):50-60. doi: 10.4049/jimmunol.1003554. Epub 2012 May 25.

50.

Relationship between inflammatory mediator patterns and anemia in HIV-1 positive and exposed children with Plasmodium falciparum malaria.

Davenport GC, Hittner JB, Were T, Ong'echa JM, Perkins DJ.

Am J Hematol. 2012 Jul;87(7):652-8. doi: 10.1002/ajh.23200. Epub 2012 May 8.

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