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Items: 1 to 50 of 52

1.

Aged marrow macrophages expand platelet-biased hematopoietic stem cells via Interleukin1B.

Frisch BJ, Hoffman CM, Latchney SE, LaMere MW, Myers J, Ashton J, Li AJ, Saunders J 2nd, Palis J, Perkins AS, McCabe A, Smith JN, McGrath KE, Rivera-Escalera F, McDavid A, Liesveld JL, Korshunov VA, Elliott MR, MacNamara KC, Becker MW, Calvi LM.

JCI Insight. 2019 Apr 18;5. pii: 124213. doi: 10.1172/jci.insight.124213.

2.

EVI1 overexpression reprograms hematopoiesis via upregulation of Spi1 transcription.

Ayoub E, Wilson MP, McGrath KE, Li AJ, Frisch BJ, Palis J, Calvi LM, Zhang Y, Perkins AS.

Nat Commun. 2018 Oct 12;9(1):4239. doi: 10.1038/s41467-018-06208-y.

3.

Leukemic presentation of diffuse large B-cell lymphoma: an unusual pattern associated with splenic involvement.

Crane GM, Perkins AS.

Blood. 2017 Nov 16;130(20):2233. doi: 10.1182/blood-2017-08-800094. No abstract available.

PMID:
29146821
4.

The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia.

Fenouille N, Bassil CF, Ben-Sahra I, Benajiba L, Alexe G, Ramos A, Pikman Y, Conway AS, Burgess MR, Li Q, Luciano F, Auberger P, Galinsky I, DeAngelo DJ, Stone RM, Zhang Y, Perkins AS, Shannon K, Hemann MT, Puissant A, Stegmaier K.

Nat Med. 2017 Mar;23(3):301-313. doi: 10.1038/nm.4283. Epub 2017 Feb 13.

5.

Stem cell-like transcriptional reprogramming mediates metastatic resistance to mTOR inhibition.

Mateo F, Arenas EJ, Aguilar H, Serra-Musach J, de Garibay GR, Boni J, Maicas M, Du S, Iorio F, Herranz-Ors C, Islam A, Prado X, Llorente A, Petit A, Vidal A, Català I, Soler T, Venturas G, Rojo-Sebastian A, Serra H, Cuadras D, Blanco I, Lozano J, Canals F, Sieuwerts AM, de Weerd V, Look MP, Puertas S, García N, Perkins AS, Bonifaci N, Skowron M, Gómez-Baldó L, Hernández V, Martínez-Aranda A, Martínez-Iniesta M, Serrat X, Cerón J, Brunet J, Barretina MP, Gil M, Falo C, Fernández A, Morilla I, Pernas S, Plà MJ, Andreu X, Seguí MA, Ballester R, Castellà E, Nellist M, Morales S, Valls J, Velasco A, Matias-Guiu X, Figueras A, Sánchez-Mut JV, Sánchez-Céspedes M, Cordero A, Gómez-Miragaya J, Palomero L, Gómez A, Gajewski TF, Cohen EEW, Jesiotr M, Bodnar L, Quintela-Fandino M, López-Bigas N, Valdés-Mas R, Puente XS, Viñals F, Casanovas O, Graupera M, Hernández-Losa J, Ramón Y Cajal S, García-Alonso L, Saez-Rodriguez J, Esteller M, Sierra A, Martín-Martín N, Matheu A, Carracedo A, González-Suárez E, Nanjundan M, Cortés J, Lázaro C, Odero MD, Martens JWM, Moreno-Bueno G, Barcellos-Hoff MH, Villanueva A, Gomis RR, Pujana MA.

Oncogene. 2017 May 11;36(19):2737-2749. doi: 10.1038/onc.2016.427. Epub 2016 Dec 19.

6.

EVI1 Interferes with Myeloid Maturation via Transcriptional Repression of Cebpa, via Binding to Two Far Downstream Regulatory Elements.

Wilson M, Tsakraklides V, Tran M, Xiao YY, Zhang Y, Perkins AS.

J Biol Chem. 2016 Jun 24;291(26):13591-607. doi: 10.1074/jbc.M115.708156. Epub 2016 Apr 21.

7.

Mice carrying a hypomorphic Evi1 allele are embryonic viable but exhibit severe congenital heart defects.

Bard-Chapeau EA, Szumska D, Jacob B, Chua BQ, Chatterjee GC, Zhang Y, Ward JM, Urun F, Kinameri E, Vincent SD, Ahmed S, Bhattacharya S, Osato M, Perkins AS, Moore AW, Jenkins NA, Copeland NG.

PLoS One. 2014 Feb 27;9(2):e89397. doi: 10.1371/journal.pone.0089397. eCollection 2014.

8.

The role of EVI1 in myeloid malignancies.

Glass C, Wilson M, Gonzalez R, Zhang Y, Perkins AS.

Blood Cells Mol Dis. 2014 Jun-Aug;53(1-2):67-76. doi: 10.1016/j.bcmd.2014.01.002. Epub 2014 Feb 1. Review.

PMID:
24495476
9.

Deletion of Mecom in mouse results in early-onset spinal deformity and osteopenia.

Juneja SC, Vonica A, Zeiss C, Lezon-Geyda K, Yatsula B, Sell DR, Monnier VM, Lin S, Ardito T, Eyre D, Reynolds D, Yao Z, Awad HA, Yu H, Wilson M, Honnons S, Boyce BF, Xing L, Zhang Y, Perkins AS.

Bone. 2014 Mar;60:148-61. doi: 10.1016/j.bone.2013.11.020. Epub 2013 Dec 4.

10.

Essential role of PR-domain protein MDS1-EVI1 in MLL-AF9 leukemia.

Zhang Y, Owens K, Hatem L, Glass CH, Karuppaiah K, Camargo F, Perkins AS.

Blood. 2013 Oct 17;122(16):2888-92. doi: 10.1182/blood-2012-08-453662. Epub 2013 Sep 10.

11.

Master regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignancies.

Bresnick EH, Katsumura KR, Lee HY, Johnson KD, Perkins AS.

Nucleic Acids Res. 2012 Jul;40(13):5819-31. doi: 10.1093/nar/gks281. Epub 2012 Apr 5. Review.

12.

Overexpression of Evi-1 oncoprotein represses TGF-β signaling in colorectal cancer.

Deng X, Cao Y, Liu Y, Li F, Sambandam K, Rajaraman S, Perkins AS, Fields AP, Hellmich MR, Townsend CM Jr, Thompson EA, Ko TC.

Mol Carcinog. 2013 Apr;52(4):255-264. doi: 10.1002/mc.21852. Epub 2011 Dec 7.

13.

Targeting a DNA binding motif of the EVI1 protein by a pyrrole-imidazole polyamide.

Zhang Y, Sicot G, Cui X, Vogel M, Wuertzer CA, Lezon-Geyda K, Wheeler J, Harki DA, Muzikar KA, Stolper DA, Dervan PB, Perkins AS.

Biochemistry. 2011 Dec 6;50(48):10431-41. doi: 10.1021/bi200962u. Epub 2011 Nov 10.

14.

PR-domain-containing Mds1-Evi1 is critical for long-term hematopoietic stem cell function.

Zhang Y, Stehling-Sun S, Lezon-Geyda K, Juneja SC, Coillard L, Chatterjee G, Wuertzer CA, Camargo F, Perkins AS.

Blood. 2011 Oct 6;118(14):3853-61. doi: 10.1182/blood-2011-02-334680. Epub 2011 Jun 10.

15.

Burkitt lymphoma in adults.

Perkins AS, Friedberg JW.

Hematology Am Soc Hematol Educ Program. 2008:341-8. doi: 10.1182/asheducation-2008.1.341. Review.

PMID:
19074108
16.

Regulation of the calreticulin gene by GATA6 and Evi-1 transcription factors.

Qiu Y, Lynch J, Guo L, Yatsula B, Perkins AS, Michalak M.

Biochemistry. 2008 Mar 25;47(12):3697-704. doi: 10.1021/bi702524v. Epub 2008 Feb 28.

PMID:
18303859
17.

Cognitive control in social situations: a role for the dorsolateral prefrontal cortex.

Weissman DH, Perkins AS, Woldorff MG.

Neuroimage. 2008 Apr 1;40(2):955-962. doi: 10.1016/j.neuroimage.2007.12.021. Epub 2007 Dec 23.

18.

Formation of Neu/ErbB2-induced mammary tumors is unaffected by loss of ErbB4.

Jackson-Fisher AJ, Bellinger G, Shum E, Duong JK, Perkins AS, Gassmann M, Muller W, Kent Lloyd KC, Stern DF.

Oncogene. 2006 Sep 14;25(41):5664-72. Epub 2006 May 1.

PMID:
16652155
19.

Assessment of F-MuLV-induced tumorigenesis reveals new candidate tumor genes including Pecam1, St7, and Prim2.

Yatsula B, Galvao C, McCrann M, Perkins AS.

Leukemia. 2006 Jan;20(1):162-5. No abstract available.

PMID:
16307020
20.

Sox4 cooperates with Evi1 in AKXD-23 myeloid tumors via transactivation of proviral LTR.

Boyd KE, Xiao YY, Fan K, Poholek A, Copeland NG, Jenkins NA, Perkins AS.

Blood. 2006 Jan 15;107(2):733-41. Epub 2005 Oct 4.

21.

Identification of binding sites of EVI1 in mammalian cells.

Yatsula B, Lin S, Read AJ, Poholek A, Yates K, Yue D, Hui P, Perkins AS.

J Biol Chem. 2005 Sep 2;280(35):30712-22. Epub 2005 Jul 8.

22.

Gene expression profiling of ErbB receptor and ligand-dependent transcription.

Amin DN, Perkins AS, Stern DF.

Oncogene. 2004 Feb 19;23(7):1428-38.

PMID:
14973552
23.

cDNA microarray analysis of invasive and tumorigenic phenotypes in a breast cancer model.

Kluger HM, Kluger Y, Gilmore-Hebert M, DiVito K, Chang JT, Rodov S, Mironenko O, Kacinski BM, Perkins AS, Sapi E.

Lab Invest. 2004 Mar;84(3):320-31.

25.

F-MuLV acceleration of myelomonocytic tumorigenesis in SV40 large T antigen transgenic mice is accompanied by retroviral insertion at Fli1 and a novel locus, Fim4.

Kone J, Arroyo J, Savinelli T, Lin S, Boyd K, Wu Y, Nimmakayalu M, Copeland NG, Jenkins NA, Qumsiyeh M, Hu P, Prescott A, Wu H, Yang L, Roe B, Perkins AS.

Leukemia. 2002 Sep;16(9):1827-34.

26.

Functional genomics in the mouse.

Perkins AS.

Funct Integr Genomics. 2002 Aug;2(3):81-91. Epub 2002 Mar 9. Review.

PMID:
12185455
27.

Clonal analysis of cutaneous fibrous histiocytoma (dermatofibroma).

Hui P, Glusac EJ, Sinard JH, Perkins AS.

J Cutan Pathol. 2002 Aug;29(7):385-9.

PMID:
12139632
28.

Development of a murine hematopoietic progenitor complementary DNA microarray using a subtracted complementary DNA library.

Ma X, Husain T, Peng H, Lin S, Mironenko O, Maun N, Johnson S, Tuck D, Berliner N, Krause DS, Perkins AS.

Blood. 2002 Aug 1;100(3):833-44.

PMID:
12130493
29.

Overexpression of parathyroid hormone-related protein causes hypercalcemia but not bone metastases in a murine model of mammary tumorigenesis.

Wysolmerski JJ, Dann PR, Zelazny E, Dunbar ME, Insogna KL, Guise TA, Perkins AS.

J Bone Miner Res. 2002 Jul;17(7):1164-70.

30.

Bethesda proposals for classification of nonlymphoid hematopoietic neoplasms in mice.

Kogan SC, Ward JM, Anver MR, Berman JJ, Brayton C, Cardiff RD, Carter JS, de Coronado S, Downing JR, Fredrickson TN, Haines DC, Harris AW, Harris NL, Hiai H, Jaffe ES, MacLennan IC, Pandolfi PP, Pattengale PK, Perkins AS, Simpson RM, Tuttle MS, Wong JF, Morse HC 3rd; Hematopathology subcommittee of the Mouse Models of Human Cancers Consortium.

Blood. 2002 Jul 1;100(1):238-45.

PMID:
12070033
31.

Cooperating oncogenic events in murine mammary tumorigenesis: assessment of ErbB2, mutant p53, and mouse mammary tumor virus.

Zelazny E, Li B, Anagnostopoulos AM, Coleman A, Perkins AS.

Exp Mol Pathol. 2001 Jun;70(3):183-93.

PMID:
11417997
32.
33.

Identification of candidate target genes for EVI-1, a zinc finger oncoprotein, using a novel selection strategy.

Kim JH, Hui P, Yue D, Aycock J, Leclerc C, Bjoring AR, Perkins AS.

Oncogene. 1998 Sep 24;17(12):1527-38.

34.

Vaccination with a recombinant vesicular stomatitis virus expressing an influenza virus hemagglutinin provides complete protection from influenza virus challenge.

Roberts A, Kretzschmar E, Perkins AS, Forman J, Price R, Buonocore L, Kawaoka Y, Rose JK.

J Virol. 1998 Jun;72(6):4704-11.

35.

Gotta find GATA a friend.

Krause DS, Perkins AS.

Nat Med. 1997 Sep;3(9):960-1. No abstract available.

PMID:
9288719
36.

neu/ERBB2 cooperates with p53-172H during mammary tumorigenesis in transgenic mice.

Li B, Rosen JM, McMenamin-Balano J, Muller WJ, Perkins AS.

Mol Cell Biol. 1997 Jun;17(6):3155-63.

37.

Retroviral insertional activation of the EVI1 oncogene does not prevent G-CSF-induced maturation of the murine pluripotent myeloid cell line 32Dcl3.

Khanna-Gupta A, Lopingco MC, Savinelli T, Zibello T, Berliner N, Perkins AS.

Oncogene. 1996 Feb 1;12(3):563-9.

PMID:
8637713
38.
39.

Molecular analysis of Evi1, a zinc finger oncogene involved in myeloid leukemia.

Lopingco MC, Perkins AS.

Curr Top Microbiol Immunol. 1996;211:211-22. Review.

PMID:
8585952
40.

Molecular regulation of myelopoiesis.

Wolff L, Perkins AS.

Trends Cell Biol. 1995 Sep;5(9):369-71. No abstract available.

PMID:
14732081
41.

Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues.

Brannan CI, Perkins AS, Vogel KS, Ratner N, Nordlund ML, Reid SW, Buchberg AM, Jenkins NA, Parada LF, Copeland NG.

Genes Dev. 1994 May 1;8(9):1019-29. Erratum in: Genes Dev 1994 Nov 15;8(22):2792.

42.

Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r).

Liu JP, Baker J, Perkins AS, Robertson EJ, Efstratiadis A.

Cell. 1993 Oct 8;75(1):59-72.

PMID:
8402901
43.

Loss of N-myc function results in embryonic lethality and failure of the epithelial component of the embryo to develop.

Stanton BR, Perkins AS, Tessarollo L, Sassoon DA, Parada LF.

Genes Dev. 1992 Dec;6(12A):2235-47.

44.

Targeting of transgene expression to monocyte/macrophages by the gp91-phox promoter and consequent histiocytic malignancies.

Skalnik DG, Dorfman DM, Perkins AS, Jenkins NA, Copeland NG, Orkin SH.

Proc Natl Acad Sci U S A. 1991 Oct 1;88(19):8505-9.

45.

Evi-1, a murine zinc finger proto-oncogene, encodes a sequence-specific DNA-binding protein.

Perkins AS, Fishel R, Jenkins NA, Copeland NG.

Mol Cell Biol. 1991 May;11(5):2665-74.

46.
47.

Targeting of transgene expression to monocytes by cytochrome b heavy chain gene 5'-flanking sequences induces histiocytic malignancies.

Skalnik DG, Dorfman DM, Perkins AS, Jenkins NA, Copeland NG, Orkin SH.

Trans Assoc Am Physicians. 1990;103:129-36. No abstract available.

PMID:
2132524
48.

The pathology of murine myelogenous leukemias.

Perkins AS.

Curr Top Microbiol Immunol. 1989;149:3-21. Review.

PMID:
2659281
49.

Transduction of the human insulin gene via retroviral vectors fails to yield spliced transcripts.

Perkins AS, Kirschmeier PT, Weinstein IB.

DNA. 1989 Jan-Feb;8(1):59-68.

PMID:
2468464
50.

Construction and characterization of a retroviral vector demonstrating efficient expression of cloned cDNA sequences.

Kirschmeier PT, Housey GM, Johnson MD, Perkins AS, Weinstein IB.

DNA. 1988 Apr;7(3):219-25.

PMID:
2836147

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