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Items: 8

1.

Early Notch Signals Induce a Pathogenic Molecular Signature during Priming of Alloantigen-Specific Conventional CD4+ T Cells in Graft-versus-Host Disease.

Chung J, Radojcic V, Perkey E, Parnell TJ, Niknafs Y, Jin X, Friedman A, Labrecque N, Blazar BR, Brennan TV, Siebel CW, Maillard I.

J Immunol. 2019 Jul 15;203(2):557-568. doi: 10.4049/jimmunol.1900192. Epub 2019 Jun 10.

PMID:
31182480
2.

Notch signaling mediated by Delta-like ligands 1 and 4 controls the pathogenesis of chronic GVHD in mice.

Radojcic V, Paz K, Chung J, Du J, Perkey ET, Flynn R, Ivcevic S, Zaiken M, Friedman A, Yan M, Pletneva MA, Sarantopoulos S, Siebel CW, Blazar BR, Maillard I.

Blood. 2018 Nov 15;132(20):2188-2200. doi: 10.1182/blood-2018-03-841155. Epub 2018 Sep 4.

PMID:
30181175
3.

An immune-beige adipocyte communication via nicotinic acetylcholine receptor signaling.

Jun H, Yu H, Gong J, Jiang J, Qiao X, Perkey E, Kim DI, Emont MP, Zestos AG, Cho JS, Liu J, Kennedy RT, Maillard I, Xu XZS, Wu J.

Nat Med. 2018 Jun;24(6):814-822. doi: 10.1038/s41591-018-0032-8. Epub 2018 May 21.

4.

New Insights into Graft-Versus-Host Disease and Graft Rejection.

Perkey E, Maillard I.

Annu Rev Pathol. 2018 Jan 24;13:219-245. doi: 10.1146/annurev-pathol-020117-043720. Epub 2017 Nov 3. Review.

PMID:
29099650
5.

Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands.

Chung J, Ebens CL, Perkey E, Radojcic V, Koch U, Scarpellino L, Tong A, Allen F, Wood S, Feng J, Friedman A, Granadier D, Tran IT, Chai Q, Onder L, Yan M, Reddy P, Blazar BR, Huang AY, Brennan TV, Bishop DK, Ludewig B, Siebel CW, Radtke F, Luther SA, Maillard I.

J Clin Invest. 2017 Apr 3;127(4):1574-1588. doi: 10.1172/JCI89535. Epub 2017 Mar 20.

6.

BCL6 Antagonizes NOTCH2 to Maintain Survival of Human Follicular Lymphoma Cells.

Valls E, Lobry C, Geng H, Wang L, Cardenas M, Rivas M, Cerchietti L, Oh P, Yang SN, Oswald E, Graham CW, Jiang Y, Hatzi K, Agirre X, Perkey E, Li Z, Tam W, Bhatt K, Leonard JP, Zweidler-McKay PA, Maillard I, Elemento O, Ci W, Aifantis I, Melnick A.

Cancer Discov. 2017 May;7(5):506-521. doi: 10.1158/2159-8290.CD-16-1189. Epub 2017 Feb 23.

7.

Increased mammalian target of rapamycin complex 2 signaling promotes age-related decline in CD4 T cell signaling and function.

Perkey E, Fingar D, Miller RA, Garcia GG.

J Immunol. 2013 Nov 1;191(9):4648-55. doi: 10.4049/jimmunol.1300750. Epub 2013 Sep 27.

8.

Ex vivo enzymatic treatment of aged CD4 T cells restores cognate T cell helper function and enhances antibody production in mice.

Perkey E, Miller RA, Garcia GG.

J Immunol. 2012 Dec 15;189(12):5582-9. doi: 10.4049/jimmunol.1200487. Epub 2012 Nov 7.

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