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Items: 1 to 50 of 68

1.

Comprehensive feature selection for classifying the treatment outcome of high-intensity ultrasound therapy in uterine fibroids.

Suomi V, Komar G, Sainio T, Joronen K, Perheentupa A, Blanco Sequeiros R.

Sci Rep. 2019 Jul 29;9(1):10907. doi: 10.1038/s41598-019-47484-y.

2.

Hormone profiling, including anti-Müllerian hormone (AMH), for the diagnosis of polycystic ovary syndrome (PCOS) and characterization of PCOS phenotypes.

Sova H, Unkila-Kallio L, Tiitinen A, Hippeläinen M, Perheentupa A, Tinkanen H, Puukka K, Bloigu R, Piltonen T, Tapanainen JS, Morin-Papunen L.

Gynecol Endocrinol. 2019 Jul;35(7):595-600. doi: 10.1080/09513590.2018.1559807. Epub 2019 Jan 22.

PMID:
30668196
3.

Wedged gel pad for bowel manipulation during MR-guided high-intensity focused ultrasound therapy to treat uterine fibroids: a case report.

Sainio T, Komar G, Saunavaara J, Suomi V, Joronen K, Perheentupa A, Viitala A, Sequeiros RB.

J Ther Ultrasound. 2018 Nov 28;6:10. doi: 10.1186/s40349-018-0116-4. eCollection 2018.

4.

An update on semen quality among young Finnish men and comparison with Danish data.

Rodprasert W, Virtanen HE, Sadov S, Perheentupa A, Skakkebaek NE, Jørgensen N, Toppari J.

Andrology. 2019 Jan;7(1):15-23. doi: 10.1111/andr.12550. Epub 2018 Sep 24.

5.

Successful microdissection testicular sperm extraction for men with non-obstructive azoospermia.

Klami R, Mankonen H, Perheentupa A.

Reprod Biol. 2018 Jun;18(2):137-142. doi: 10.1016/j.repbio.2018.03.003. Epub 2018 Mar 27. Review.

PMID:
29602610
6.

Secreted frizzled-related protein 2 (SFRP2) expression promotes lesion proliferation via canonical WNT signaling and indicates lesion borders in extraovarian endometriosis.

Heinosalo T, Gabriel M, Kallio L, Adhikari P, Huhtinen K, Laajala TD, Kaikkonen E, Mehmood A, Suvitie P, Kujari H, Aittokallio T, Perheentupa A, Poutanen M.

Hum Reprod. 2018 May 1;33(5):817-831. doi: 10.1093/humrep/dey026.

PMID:
29462326
7.

Microdissection testicular sperm extraction in Finland - results of the first 100 patients.

Klami R, Mankonen H, Perheentupa A.

Acta Obstet Gynecol Scand. 2018 Jan;97(1):53-58. doi: 10.1111/aogs.13243. Epub 2017 Nov 5.

PMID:
28990672
8.

Roles of human epididymis protein 4, carbohydrate antigen 125, inhibin B and anti-Müllerian hormone in the differential diagnosis and follow-up of ovarian granulosa cell tumors.

Haltia UM, Hallamaa M, Tapper J, Hynninen J, Alfthan H, Kalra B, Ritvos O, Heikinheimo M, Unkila-Kallio L, Perheentupa A, Färkkilä A.

Gynecol Oncol. 2017 Jan;144(1):83-89. doi: 10.1016/j.ygyno.2016.11.018. Epub 2016 Nov 18.

PMID:
27871721
9.

Reply to Eugenio Ventimiglia, Francesco Montorsi, and Andrea Salonia's Letter to the Editor re: Jakob Damsgaard, Ulla N. Joensen, Elisabeth Carlsen, et al. Varicocele Is Associated with Impaired Semen Quality and Reproductive Hormone Levels: A Study of 7035 Healthy Young Men from Six European Countries. Eur Urol 2016;70:1019-29.

Damsgaard J, Joensen UN, Carlsen E, Erenpreiss J, Jensen MB, Matulevicius V, Zilaitiene B, Olesen IA, Perheentupa A, Punab M, Salzbrunn A, Toppari J, Virtanen HE, Juul A, Skakkebæk NE, Jørgensen N.

Eur Urol. 2017 Feb;71(2):e71-e72. doi: 10.1016/j.eururo.2016.09.002. Epub 2016 Sep 13. No abstract available.

PMID:
27638092
10.

A Nanoparticle-Lectin Immunoassay Improves Discrimination of Serum CA125 from Malignant and Benign Sources.

Gidwani K, Huhtinen K, Kekki H, van Vliet S, Hynninen J, Koivuviita N, Perheentupa A, Poutanen M, Auranen A, Grenman S, Lamminmäki U, Carpen O, van Kooyk Y, Pettersson K.

Clin Chem. 2016 Oct;62(10):1390-400. doi: 10.1373/clinchem.2016.257691. Epub 2016 Aug 18.

11.

Varicocele Is Associated with Impaired Semen Quality and Reproductive Hormone Levels: A Study of 7035 Healthy Young Men from Six European Countries.

Damsgaard J, Joensen UN, Carlsen E, Erenpreiss J, Blomberg Jensen M, Matulevicius V, Zilaitiene B, Olesen IA, Perheentupa A, Punab M, Salzbrunn A, Toppari J, Virtanen HE, Juul A, Skakkebæk NE, Jørgensen N.

Eur Urol. 2016 Dec;70(6):1019-1029. doi: 10.1016/j.eururo.2016.06.044. Epub 2016 Jul 14.

PMID:
27423503
12.

Testicular Growth During Puberty in Boys With and Without a History of Congenital Cryptorchidism.

Sadov S, Koskenniemi JJ, Virtanen HE, Perheentupa A, Petersen JH, Skakkebaek NE, Main KM, Toppari J.

J Clin Endocrinol Metab. 2016 Jun;101(6):2570-7. doi: 10.1210/jc.2015-3329. Epub 2016 Apr 6.

PMID:
27049351
13.

[Supraventricular tachycardia during pregnancy].

Lehtoranta L, Valta M, Aantaa R, Perheentupa A.

Duodecim. 2016;132(2):173-5. Finnish.

PMID:
26939491
14.

Semen quality improves marginally during young adulthood: a longitudinal follow-up study.

Perheentupa A, Sadov S, Rönkä R, Virtanen HE, Rodprasert W, Vierula M, Jørgensen N, Skakkebæk NE, Toppari J.

Hum Reprod. 2016 Mar;31(3):502-10. doi: 10.1093/humrep/dev328. Epub 2016 Jan 5.

15.

[How to interpret a semen sample?].

Klami R, Perheentupa A.

Duodecim. 2015;131(21):1969-73. Finnish.

PMID:
26677546
16.

Prevalence of Pain Symptoms Suggestive of Endometriosis Among Finnish Adolescent Girls (TEENMAPS Study).

Suvitie PA, Hallamaa MK, Matomäki JM, Mäkinen JI, Perheentupa AH.

J Pediatr Adolesc Gynecol. 2016 Apr;29(2):97-103. doi: 10.1016/j.jpag.2015.07.001. Epub 2015 Jul 11.

PMID:
26169662
17.

Intra-tissue steroid profiling indicates differential progesterone and testosterone metabolism in the endometrium and endometriosis lesions.

Huhtinen K, Saloniemi-Heinonen T, Keski-Rahkonen P, Desai R, Laajala D, Ståhle M, Häkkinen MR, Awosanya M, Suvitie P, Kujari H, Aittokallio T, Handelsman DJ, Auriola S, Perheentupa A, Poutanen M.

J Clin Endocrinol Metab. 2014 Nov;99(11):E2188-97. doi: 10.1210/jc.2014-1913. Epub 2014 Aug 19.

PMID:
25137424
18.

Ovarian endometriosis signatures established through discovery and directed mass spectrometry analysis.

Vehmas AP, Muth-Pawlak D, Huhtinen K, Saloniemi-Heinonen T, Jaakkola K, Laajala TD, Kaprio H, Suvitie PA, Aittokallio T, Siitari H, Perheentupa A, Poutanen M, Corthals GL.

J Proteome Res. 2014 Nov 7;13(11):4983-94. doi: 10.1021/pr500384n. Epub 2014 Aug 20.

PMID:
25099244
19.

Serum concentrations of HE4 change little during in vitro fertilization.

Hallamaa M, Huhtinen K, Suvitie P, Perheentupa A.

Acta Obstet Gynecol Scand. 2014 Jul;93(7):640-6. doi: 10.1111/aogs.12393. Epub 2014 May 12.

PMID:
24734893
20.

[Achievement of educational goals among the trainees of obstetrics and gynaecology in the university of Turku].

Mäkinen J, Manninen SM, Perheentupa A, Lehto S.

Duodecim. 2013;129(8):833-9. Finnish.

PMID:
23720951
21.

Predictive value of serum human epididymis protein 4 and cancer antigen 125 concentrations in endometrial carcinoma.

Saarelainen SK, Peltonen N, Lehtimäki T, Perheentupa A, Vuento MH, Mäenpää JU.

Am J Obstet Gynecol. 2013 Aug;209(2):142.e1-6. doi: 10.1016/j.ajog.2013.04.014. Epub 2013 Apr 10.

PMID:
23583212
22.

A cohort effect on serum testosterone levels in Finnish men.

Perheentupa A, Mäkinen J, Laatikainen T, Vierula M, Skakkebaek NE, Andersson AM, Toppari J.

Eur J Endocrinol. 2013 Jan 17;168(2):227-33. doi: 10.1530/EJE-12-0288. Print 2013 Feb.

PMID:
23161753
23.

Endometrial and endometriotic concentrations of estrone and estradiol are determined by local metabolism rather than circulating levels.

Huhtinen K, Desai R, Ståhle M, Salminen A, Handelsman DJ, Perheentupa A, Poutanen M.

J Clin Endocrinol Metab. 2012 Nov;97(11):4228-35. doi: 10.1210/jc.2012-1154. Epub 2012 Sep 11.

24.

Serum HE4 concentration is not dependent on menstrual cycle or hormonal treatment among endometriosis patients and healthy premenopausal women.

Hallamaa M, Suvitie P, Huhtinen K, Matomäki J, Poutanen M, Perheentupa A.

Gynecol Oncol. 2012 Jun;125(3):667-72. doi: 10.1016/j.ygyno.2012.03.011. Epub 2012 Mar 14.

PMID:
22426487
25.

Relation of total and free testosterone and sex hormone-binding globulin with cardiovascular risk factors in men aged 24-45 years. The Cardiovascular Risk in Young Finns Study.

Firtser S, Juonala M, Magnussen CG, Jula A, Loo BM, Marniemi J, Viikari JS, Toppari J, Perheentupa A, Hutri-Kähönen N, Raitakari OT.

Atherosclerosis. 2012 May;222(1):257-62. doi: 10.1016/j.atherosclerosis.2012.02.020. Epub 2012 Feb 21.

PMID:
22420889
26.

Metformin improves pregnancy and live-birth rates in women with polycystic ovary syndrome (PCOS): a multicenter, double-blind, placebo-controlled randomized trial.

Morin-Papunen L, Rantala AS, Unkila-Kallio L, Tiitinen A, Hippeläinen M, Perheentupa A, Tinkanen H, Bloigu R, Puukka K, Ruokonen A, Tapanainen JS.

J Clin Endocrinol Metab. 2012 May;97(5):1492-500. doi: 10.1210/jc.2011-3061. Epub 2012 Mar 14.

PMID:
22419702
27.

[Myomas and fertility].

Suvitie P, Perheentupa A.

Duodecim. 2011;127(17):1848-56. Finnish.

PMID:
21995121
28.

[Pathogenesis of endometriosis].

Huhtinen K, Perheentupa A, Poutanen M, Heikinheimo O.

Duodecim. 2011;127(17):1827-35. Finnish.

PMID:
21995119
29.

Estrogen biosynthesis and signaling in endometriosis.

Huhtinen K, Ståhle M, Perheentupa A, Poutanen M.

Mol Cell Endocrinol. 2012 Jul 25;358(2):146-54. doi: 10.1016/j.mce.2011.08.022. Epub 2011 Aug 22. Review.

PMID:
21875644
30.

Endogenous testosterone and brachial artery endothelial function in middle-aged men with symptoms of late-onset hypogonadism.

Mäkinen JI, Perheentupa A, Irjala K, Pöllänen P, Mäkinen J, Huhtaniemi I, Raitakari OT.

Aging Male. 2011 Dec;14(4):237-42. doi: 10.3109/13685538.2011.593655. Epub 2011 Aug 11.

PMID:
21831030
31.

Serum HE4 Profile During Primary Chemotherapy of Epithelial Ovarian Cancer.

Hynninen J, Auranen A, Dean K, Lavonius M, Carpen O, Perheentupa A, Seppänen M, Grénman S.

Int J Gynecol Cancer. 2011 Dec;21(9):1573-8. doi: 10.1097/IGC.0b013e3182225509.

PMID:
21811175
32.

Unfavorable hormonal, metabolic, and inflammatory alterations persist after menopause in women with PCOS.

Puurunen J, Piltonen T, Morin-Papunen L, Perheentupa A, Järvelä I, Ruokonen A, Tapanainen JS.

J Clin Endocrinol Metab. 2011 Jun;96(6):1827-34. doi: 10.1210/jc.2011-0039. Epub 2011 Mar 30.

PMID:
21450988
33.

Recent adverse trends in semen quality and testis cancer incidence among Finnish men.

Jørgensen N, Vierula M, Jacobsen R, Pukkala E, Perheentupa A, Virtanen HE, Skakkebaek NE, Toppari J.

Int J Androl. 2011 Aug;34(4 Pt 2):e37-48. doi: 10.1111/j.1365-2605.2010.01133.x. Epub 2011 Mar 2.

34.

Novel hydroxysteroid (17beta) dehydrogenase 1 inhibitors reverse estrogen-induced endometrial hyperplasia in transgenic mice.

Saloniemi T, Järvensivu P, Koskimies P, Jokela H, Lamminen T, Ghaem-Maghami S, Dina R, Damdimopoulou P, Mäkelä S, Perheentupa A, Kujari H, Brosens J, Poutanen M.

Am J Pathol. 2010 Mar;176(3):1443-51. doi: 10.2353/ajpath.2010.090325. Epub 2010 Jan 21.

35.

Resampling reveals sample-level differential expression in clinical genome-wide studies.

Hiissa J, Elo LL, Huhtinen K, Perheentupa A, Poutanen M, Aittokallio T.

OMICS. 2009 Oct;13(5):381-96. doi: 10.1089/omi.2009.0027.

PMID:
19663710
36.

[Diagnosis and therapy of male hormonal changes related to aging].

Huhtaniemi I, Perheentupa A.

Duodecim. 2009;125(10):1099-106. Finnish.

PMID:
19585907
37.

Serum HE4 concentration differentiates malignant ovarian tumours from ovarian endometriotic cysts.

Huhtinen K, Suvitie P, Hiissa J, Junnila J, Huvila J, Kujari H, Setälä M, Härkki P, Jalkanen J, Fraser J, Mäkinen J, Auranen A, Poutanen M, Perheentupa A.

Br J Cancer. 2009 Apr 21;100(8):1315-9. doi: 10.1038/sj.bjc.6605011. Epub 2009 Mar 31.

38.

Aging of the human ovary and testis.

Perheentupa A, Huhtaniemi I.

Mol Cell Endocrinol. 2009 Feb 5;299(1):2-13. doi: 10.1016/j.mce.2008.11.004. Epub 2008 Nov 18. Review.

PMID:
19059459
39.

Smoking and low serum testosterone associates with high concentration of oxidized LDL.

Linna MS, Ahotupa M, Irjala K, Pöllänen P, Huhtaniemi I, Mäkinen J, Perheentupa A, Vasankari TJ.

Ann Med. 2008;40(8):634-40. doi: 10.1080/07853890802161007.

PMID:
18608119
40.

Male hormonal contraception: a double-blind, placebo-controlled study.

Mommers E, Kersemaekers WM, Elliesen J, Kepers M, Apter D, Behre HM, Beynon J, Bouloux PM, Costantino A, Gerbershagen HP, Grønlund L, Heger-Mahn D, Huhtaniemi I, Koldewijn EL, Lange C, Lindenberg S, Meriggiola MC, Meuleman E, Mulders PF, Nieschlag E, Perheentupa A, Solomon A, Väisälä L, Wu FC, Zitzmann M.

J Clin Endocrinol Metab. 2008 Jul;93(7):2572-80. doi: 10.1210/jc.2008-0265. Epub 2008 Apr 15.

PMID:
18413423
41.

Late-onset hypogonadism in men. Experience from the Turku Male Ageing Study (TuMAS).

Huhtaniemi I, Mäkinen JI, Perheentupa A, Raitakari OT.

Hormones (Athens). 2008 Jan-Mar;7(1):36-45.

42.

Sexual symptoms in aging men indicate poor life satisfaction and increased health service consumption.

Mäkinen JI, Perheentupa A, Raitakari OT, Koskenvuo M, Pöllänen P, Mäkinen J, Huhtaniemi I.

Urology. 2007 Dec;70(6):1194-9.

PMID:
18158046
43.

Does the andropause exist?

Perheentupa A, Huhtaniemi I.

Nat Clin Pract Endocrinol Metab. 2007 Oct;3(10):670-1. Epub 2007 Aug 28. Review. No abstract available.

PMID:
17724483
44.

Endogenous testosterone and serum lipids in middle-aged men.

Mäkinen JI, Perheentupa A, Irjala K, Pöllänen P, Mäkinen J, Huhtaniemi I, Raitakari OT.

Atherosclerosis. 2008 Apr;197(2):688-93. Epub 2007 Jun 22.

PMID:
17588587
45.

Evaluation of factor V Leiden, prothrombin and methylenetetrahydrofolate reductase gene mutations in patients with severe pregnancy complications in northern Finland.

Jarvenpaa J, Pakkila M, Savolainen ER, Perheentupa A, Jarvela I, Ryynanen M.

Gynecol Obstet Invest. 2006;62(1):28-32. Epub 2006 Mar 1. Erratum in: Gynecol Obstet Invest. 2009;68(1):71.

PMID:
16514238
46.

A multicentre study investigating subcutaneous etonogestrel implants with injectable testosterone decanoate as a potential long-acting male contraceptive.

Brady BM, Amory JK, Perheentupa A, Zitzmann M, Hay CJ, Apter D, Anderson RA, Bremner WJ, Pollanen P, Nieschlag E, Wu FC, Kersemaekers WM.

Hum Reprod. 2006 Jan;21(1):285-94. Epub 2005 Sep 19.

PMID:
16172147
47.

[Primary dysmenorrhea painful menstruation].

Perheentupa A, Erkkola R, Koulu M.

Duodecim. 2005;121(13):1411-8. Review. Finnish. No abstract available.

PMID:
16134714
48.

Increased carotid atherosclerosis in andropausal middle-aged men.

Mäkinen J, Järvisalo MJ, Pöllänen P, Perheentupa A, Irjala K, Koskenvuo M, Mäkinen J, Huhtaniemi I, Raitakari OT.

J Am Coll Cardiol. 2005 May 17;45(10):1603-8.

49.

Serum anti-Müllerian hormone levels remain high until late reproductive age and decrease during metformin therapy in women with polycystic ovary syndrome.

Piltonen T, Morin-Papunen L, Koivunen R, Perheentupa A, Ruokonen A, Tapanainen JS.

Hum Reprod. 2005 Jul;20(7):1820-6. Epub 2005 Mar 31.

PMID:
15802325
50.

Transdermal estradiol treatment suppresses serum gonadotropins during lactation without transfer into breast milk.

Perheentupa A, Ruokonen A, Tapanainen JS.

Fertil Steril. 2004 Oct;82(4):903-7.

PMID:
15482766

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