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Items: 32

1.

Efficacy of flupirtine on cognitive function in patients with CJD: A double-blind study.

Otto M, Cepek L, Ratzka P, Doehlinger S, Boekhoff I, Wiltfang J, Irle E, Pergande G, Ellers-Lenz B, Windl O, Kretzschmar HA, Poser S, Prange H.

Neurology. 2004 Mar 9;62(5):714-8.

PMID:
15007119
2.

[Reduction of spastic increased muscle tone in multiple sclerosis by the nonopioid analgesic flupirtine].

Göbel H, Schmid J, Heinze A, Pergande G.

Schmerz. 1999 Oct 15;13(5):324-31. German.

PMID:
12799920
3.

Prevention of glutathione depletion-induced apoptosis in cultured human RPE cells by flupirtine.

Wood JP, Pergande G, Osborne NN.

Restor Neurol Neurosci. 1998 Jun;12(2-3):119-25.

PMID:
12671306
4.

SELEDO: a 5-year long-term trial on the effect of selegiline in early Parkinsonian patients treated with levodopa.

Przuntek H, Conrad B, Dichgans J, Kraus PH, Krauseneck P, Pergande G, Rinne U, Schimrigk K, Schnitker J, Vogel HP.

Eur J Neurol. 1999 Mar;6(2):141-50.

PMID:
10053226
5.

Effect of flupirtine on cell death of human umbilical vein endothelial cells induced by reactive oxygen species.

Lorenz B, Schlüter T, Bohnensack R, Pergande G, Müller WE.

Biochem Pharmacol. 1998 Dec 15;56(12):1615-24.

PMID:
9973182
6.

Antioxidant properties of the triaminopyridine, flupirtine.

Gassen M, Pergande G, Youdim MB.

Biochem Pharmacol. 1998 Nov 15;56(10):1323-9.

PMID:
9825731
7.

Pharmacological intervention in age-associated brain disorders by Flupirtine: Alzheimer's and prion diseases.

Perovic S, Böhm M, Meesters E, Meinhardt A, Pergande G, Müller WE.

Mech Ageing Dev. 1998 Mar 16;101(1-2):1-19.

PMID:
9593309
8.

Effect of the triaminopyridine flupirtine on calcium uptake, membrane potential and ATP synthesis in rat heart mitochondria.

Zimmer G, Balakirev M, Zwicker K, Hofmann M, Woodcock BG, Pergande G.

Br J Pharmacol. 1998 Mar;123(6):1154-8.

9.

Flupirtine, a nonopioid centrally acting analgesic, acts as an NMDA antagonist.

Osborne NN, Cazevieille C, Wood JP, Nash MS, Pergande G, Block F, Kosinski C, Schwarz M.

Gen Pharmacol. 1998 Mar;30(3):255-63. Review.

PMID:
9510072
10.

Effect of flupirtine on Bcl-2 and glutathione level in neuronal cells treated in vitro with the prion protein fragment (PrP106-126).

Perovic S, Schröder HC, Pergande G, Ushijima H, Müller WE.

Exp Neurol. 1997 Oct;147(2):518-24.

PMID:
9344576
11.

Induction of apoptosis in cultured human retinal pigment epithelial cells is counteracted by flupirtine.

Osborne NN, Cazevieille C, Pergande G, Wood JP.

Invest Ophthalmol Vis Sci. 1997 Jun;38(7):1390-400.

PMID:
9191602
12.
13.

Antiparkinsonian and other motor effects of flupirtine alone and in combination with dopaminergic drugs.

Schmidt WJ, Schuster G, Wacker E, Pergande G.

Eur J Pharmacol. 1997 May 26;327(1):1-9.

PMID:
9185829
14.

Flupirtine reduces functional deficits and neuronal damage after global ischemia in rats.

Block F, Pergande G, Schwarz M.

Brain Res. 1997 Apr 18;754(1-2):279-84.

PMID:
9134985
15.

Flupirtine protects both neuronal cells and lymphocytes against induced apoptosis in vitro: implications for treatment of AIDS patients.

Müller WE, Dobmeyer JM, Dobmeyer TS, Pergande G, Perovic S, Leuck J, Rossol R.

Cell Death Differ. 1997 Jan;4(1):51-8.

16.

[Flupirtine in comparison with chlormezanone in chronic musculoskeletal back pain. Results of a multicenter randomized double-blind study].

Wörz R, Bolten W, Heller B, Krainick JU, Pergande G.

Fortschr Med. 1996 Dec 20;114(35-36):500-4. German.

PMID:
9119352
17.

Flupirtine increases the levels of glutathione and Bc1-2 in hNT (human Ntera/D1) neurons: mode of action of the drug-mediated anti-apoptotic effect.

Perovic S, Pialoglou P, Schröder HC, Pergande G, Müller WE.

Eur J Pharmacol. 1996 Dec 12;317(1):157-64.

PMID:
8982732
18.

Protection of rabbit retina from ischemic injury by flupirtine.

Osborne NN, Schwarz M, Pergande G.

Invest Ophthalmol Vis Sci. 1996 Feb;37(2):274-80.

PMID:
8603831
19.

Neurotoxicity in rat cortical cells caused by N-methyl-D-aspartate (NMDA) and gp120 of HIV-1: induction and pharmacological intervention.

Müller WE, Pergande G, Ushijima H, Schleger C, Kelve M, Perovic S.

Prog Mol Subcell Biol. 1996;16:44-57.

PMID:
8822791
20.

Antiparkinsonian effect of flupirtine in monoamine-depleted rats.

Schwarz M, Nolden-Koch M, Purr J, Pergande G, Block F.

J Neural Transm (Vienna). 1996;103(5):581-90.

PMID:
8811503
21.

Flupirtine partially prevents neuronal injury induced by prion protein fragment and lead acetate.

Perovic S, Pergande G, Ushijima H, Kelve M, Forrest J, Müller WE.

Neurodegeneration. 1995 Dec;4(4):369-74.

PMID:
8846229
22.
24.

Flupirtine protects against ischaemic retinal dysfunction in rats.

Block F, Pergande G, Schwarz M.

Neuroreport. 1994 Dec 20;5(18):2630-2.

PMID:
7696619
25.

The triaminopyridine flupirtine prevents cell death in rat cortical cells induced by N-methyl-D-aspartate and gp120 of HIV-1.

Perovic S, Schleger C, Pergande G, Iskric S, Ushijima H, Rytik P, Müller WE.

Eur J Pharmacol. 1994 Dec 15;288(1):27-33.

PMID:
7705465
26.

N-methyl-D-aspartate (NMDA)-mediated muscle relaxant action of flupirtine in rats.

Schwarz M, Block F, Pergande G.

Neuroreport. 1994 Oct 3;5(15):1981-4.

PMID:
7841390
27.

[Antiglaucoma ophthalmic agents with prolonged action based on macromolecular excipients. 2. In vivo studies].

Pergande G, Keipert S, Klatt A.

Pharmazie. 1990 Jul;45(8):587-91. German.

PMID:
2080204
28.
29.

[Progress in the field of drug development. 22].

Henkler G, Klotzbach M, Koch H, Müller W, Pergande G, Richter J.

Pharmazie. 1989 Apr;44(4):241-50. Review. German. No abstract available.

PMID:
2672034
30.

[Progress in the field of drug development. 21].

Délenk-Heydenreich K, Henkler G, Keller U, Klotzbach M, Koch H, Müller W, Pergande G, Richter J.

Pharmazie. 1988 Apr;43(4):233-43. Review. German. No abstract available.

PMID:
3045843
31.

[Progress in the field of drug development. 20].

Délenk-Heidenreich K, Henkler G, Keller U, Klotzbach M, Koch H, Müller W, Pergande G, Richter J.

Pharmazie. 1987 Jul;42(7):433-47. Review. German. No abstract available.

PMID:
3313439
32.

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