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Items: 1 to 50 of 298

1.

A ubiquitin-like domain is required for stabilizing the N-terminal ATPase module of human SMCHD1.

Pedersen LC, Inoue K, Kim S, Perera L, Shaw ND.

Commun Biol. 2019 Jul 10;2(1):255. doi: 10.1038/s42003-019-0499-y.

PMID:
31925095
2.

Hydrophobic ligands influence the structure, stability, and processing of the major cockroach allergen Bla g 1.

Foo ACY, Thompson PM, Perera L, Arora S, DeRose EF, Williams J, Mueller GA.

Sci Rep. 2019 Dec 4;9(1):18294. doi: 10.1038/s41598-019-54689-8.

3.

Vaccine-induced T cell protection from influenza viruses.

Valkenburg SA, Li OTW, Peiris JSM, Perera LP, Poon LLM.

Hong Kong Med J. 2019 Oct;25 Suppl 7(7):33-36. No abstract available.

4.

Ligand induced dissociation of the AR homodimer precedes AR monomer translocation to the nucleus.

Shizu R, Yokobori K, Perera L, Pedersen L, Negishi M.

Sci Rep. 2019 Nov 13;9(1):16734. doi: 10.1038/s41598-019-53139-9.

5.

Reversal of drug resistance by JS-K and nitric oxide in ABCB1- and ABCG2-expressing multi-drug resistant human tumor cells.

Sinha BK, Perera L, Cannon RE.

Biomed Pharmacother. 2019 Dec;120:109468. doi: 10.1016/j.biopha.2019.109468. Epub 2019 Oct 9.

6.

Outcomes for elderly patients 75 years and older treated with curative intent radiotherapy for mucosal squamous cell carcinomas of the head and neck.

Horsley PJ, Perera L, Veness MJ, Stevens MJ, Eade TN, Back M, Brown C, Jayamanne DT.

Head Neck. 2020 Jan;42(1):25-32. doi: 10.1002/hed.25969. Epub 2019 Oct 8.

PMID:
31593357
7.

An oligomeric state-dependent switch in the ER enzyme FICD regulates AMPylation and deAMPylation of BiP.

Perera LA, Rato C, Yan Y, Neidhardt L, McLaughlin SH, Read RJ, Preissler S, Ron D.

EMBO J. 2019 Oct 4;38(21):e102177. doi: 10.15252/embj.2019102177. Epub 2019 Sep 18.

8.

Mitochondrial single-stranded DNA binding protein novel de novo SSBP1 mutation in a child with single large-scale mtDNA deletion (SLSMD) clinically manifesting as Pearson, Kearns-Sayre, and Leigh syndromes.

Gustafson MA, McCormick EM, Perera L, Longley MJ, Bai R, Kong J, Dulik M, Shen L, Goldstein AC, McCormack SE, Laskin BL, Leroy BP, Ortiz-Gonzalez XR, Ellington MG, Copeland WC, Falk MJ.

PLoS One. 2019 Sep 3;14(9):e0221829. doi: 10.1371/journal.pone.0221829. eCollection 2019.

9.

Tuning receptors for the encapsulation of beryllium2.

Nixon DJ, Perera LC, Dais TN, Brothers PJ, Henderson W, Plieger PG.

Phys Chem Chem Phys. 2019 Sep 21;21(35):19660-19666. doi: 10.1039/c9cp04043a. Epub 2019 Aug 30.

PMID:
31469139
10.

A "One-Stop" Screening Protocol for Haemoglobinopathy Traits and Iron Deficiency in Sri Lanka.

Allen A, Perera S, Perera L, Rodrigo R, Mettananda S, Matope A, Silva I, Hameed N, Fisher CA, Olivieri N, Weatherall DJ, Allen S, Premawardhena A.

Front Mol Biosci. 2019 Aug 9;6:66. doi: 10.3389/fmolb.2019.00066. eCollection 2019.

11.

Characterization of Estrogenic and Androgenic Activities for Bisphenol A-like Chemicals (BPs): In Vitro Estrogen and Androgen Receptors Transcriptional Activation, Gene Regulation, and Binding Profiles.

Pelch KE, Li Y, Perera L, Thayer KA, Korach KS.

Toxicol Sci. 2019 Aug 6. pii: kfz173. doi: 10.1093/toxsci/kfz173. [Epub ahead of print]

PMID:
31388671
12.

A ubiquitin-like domain is required for stabilizing the N-terminal ATPase module of human SMCHD1.

Pedersen LC, Inoue K, Kim S, Perera L, Shaw ND.

Commun Biol. 2019 Jul 10;2:255. doi: 10.1038/s42003-019-0499-y. eCollection 2019.

13.

Determining the endocrine disruption potential of industrial chemicals using an integrative approach: Public databases, in vitro exposure, and modeling receptor interactions.

Alofe O, Kisanga E, Inayat-Hussain SH, Fukumura M, Garcia-Milian R, Perera L, Vasiliou V, Whirledge S.

Environ Int. 2019 Oct;131:104969. doi: 10.1016/j.envint.2019.104969. Epub 2019 Jul 13.

14.

IL15 by Continuous Intravenous Infusion to Adult Patients with Solid Tumors in a Phase I Trial Induced Dramatic NK-Cell Subset Expansion.

Conlon KC, Potter EL, Pittaluga S, Lee CR, Miljkovic MD, Fleisher TA, Dubois S, Bryant BR, Petrus M, Perera LP, Hsu J, Figg WD, Peer CJ, Shih JH, Yovandich JL, Creekmore SP, Roederer M, Waldmann TA.

Clin Cancer Res. 2019 Aug 15;25(16):4945-4954. doi: 10.1158/1078-0432.CCR-18-3468. Epub 2019 May 29.

15.

The tandem zinc finger RNA binding domain of members of the tristetraprolin protein family.

Lai WS, Wells ML, Perera L, Blackshear PJ.

Wiley Interdiscip Rev RNA. 2019 Jul;10(4):e1531. doi: 10.1002/wrna.1531. Epub 2019 Mar 12. Review.

PMID:
30864256
16.

A Low-Diversity Microbiota Inhabits Extreme Terrestrial Basaltic Terrains and Their Fumaroles: Implications for the Exploration of Mars.

Cockell CS, Harrison JP, Stevens AH, Payler SJ, Hughes SS, Kobs Nawotniak SE, Brady AL, Elphic RC, Haberle CW, Sehlke A, Beaton KH, Abercromby AFJ, Schwendner P, Wadsworth J, Landenmark H, Cane R, Dickinson AW, Nicholson N, Perera L, Lim DSS.

Astrobiology. 2019 Mar;19(3):284-299. doi: 10.1089/ast.2018.1870.

17.

The p.H63D allele of the HFE gene protects against low iron stores in Sri Lanka.

Allen A, Premawardhena A, Allen S, Rodrigo R, Manamperi A, Perera L, Wray K, Armitage A, Fisher C, Drakesmith A, Robson K, Weatherall D.

Blood Cells Mol Dis. 2019 May;76:72-77. doi: 10.1016/j.bcmd.2019.02.004. Epub 2019 Feb 20.

PMID:
30827762
18.

Presence of Irritable Bowel Syndrome Symptoms in Quiescent Inflammatory Bowel Disease Is Associated with High Rate of Anxiety and Depression.

Perera LP, Radigan M, Guilday C, Banerjee I, Eastwood D, Babygirija R, Massey BT.

Dig Dis Sci. 2019 Jul;64(7):1923-1928. doi: 10.1007/s10620-019-05488-8. Epub 2019 Feb 6.

PMID:
30725303
19.

The Regulation of Skin Fibrosis in Systemic Sclerosis by Extracellular ATP via P2Y2 Purinergic Receptor.

Perera LMB, Sekiguchi A, Uchiyama A, Uehara A, Fujiwara C, Yamazaki S, Yokoyama Y, Ogino S, Torii R, Hosoi M, Ishikawa O, Motegi SI.

J Invest Dermatol. 2019 Apr;139(4):890-899. doi: 10.1016/j.jid.2018.10.027. Epub 2018 Nov 4.

PMID:
30404019
20.

Anaemia among females in child-bearing age: Relative contributions, effects and interactions of α- and β-thalassaemia.

Mettananda S, Suranjan M, Fernando R, Dias T, Mettananda C, Rodrigo R, Perera L, Gibbons R, Premawardhena A, Higgs D.

PLoS One. 2018 Nov 2;13(11):e0206928. doi: 10.1371/journal.pone.0206928. eCollection 2018.

21.

A Bioactive Resveratrol Trimer from the Stem Bark of the Sri Lankan Endemic Plant Vateria copallifera.

Samaradivakara SP, Samarasekera R, Handunnetti SM, Weerasena OVDSJ, Al-Hamashi AA, Slama JT, Taylor WR, Alhadidi Q, Shah ZA, Perera L, Tillekeratne LMV.

J Nat Prod. 2018 Aug 24;81(8):1693-1700. doi: 10.1021/acs.jnatprod.7b00892. Epub 2018 Jul 24.

PMID:
30040425
22.

Protection by universal influenza vaccine is mediated by memory CD4 T cells.

Valkenburg SA, Li OTW, Li A, Bull M, Waldmann TA, Perera LP, Peiris M, Poon LLM.

Vaccine. 2018 Jul 5;36(29):4198-4206. doi: 10.1016/j.vaccine.2018.06.007. Epub 2018 Jun 7.

PMID:
29887326
23.

Case study on the soil antibiotic resistome in an urban community garden.

Mafiz A, Perera LN, He Y, Zhang W, Xiao S, Hao W, Sun S, Zhou K, Zhang Y.

Int J Antimicrob Agents. 2018 Aug;52(2):241-250. doi: 10.1016/j.ijantimicag.2018.05.016. Epub 2018 May 30.

PMID:
29857032
24.

Identification of the effector domain of biglycan that facilitates BMP-2 osteogenic function.

Jongwattanapisan P, Terajima M, Miguez PA, Querido W, Nagaoka H, Sumida N, Gurysh EG, Ainslie KM, Pleshko N, Perera L, Yamauchi M.

Sci Rep. 2018 May 4;8(1):7022. doi: 10.1038/s41598-018-25279-x.

25.

Pattern of dengue virus infections in adult patients from Sri Lanka.

Jayarajah U, de Silva PK, Jayawardana P, Dissanayake U, Kulatunga A, Fernando H, Perera L, Kannangara V, Udayangani C, Peiris R, Faizer S, Yasawardene P, de Zoysa I, Seneviratne SL.

Trans R Soc Trop Med Hyg. 2018 Mar 1;112(3):144-153. doi: 10.1093/trstmh/try034.

PMID:
29726966
26.

Advanced Age Does Not Negatively Impact Health-Related Quality of Life in Inflammatory Bowel Disease.

Perera LP, Bhandari S, Liu R, Guilday C, Zadvornova Y, Saeian K, Eastwood D.

Dig Dis Sci. 2018 Jul;63(7):1787-1793. doi: 10.1007/s10620-018-5076-6. Epub 2018 Apr 30.

PMID:
29713985
27.

GATA3 zinc finger 2 mutations reprogram the breast cancer transcriptional network.

Takaku M, Grimm SA, Roberts JD, Chrysovergis K, Bennett BD, Myers P, Perera L, Tucker CJ, Perou CM, Wade PA.

Nat Commun. 2018 Mar 13;9(1):1059. doi: 10.1038/s41467-018-03478-4.

28.

Probing Dominant Negative Behavior of Glucocorticoid Receptor β through a Hybrid Structural and Biochemical Approach.

Min J, Perera L, Krahn JM, Jewell CM, Moon AF, Cidlowski JA, Pedersen LC.

Mol Cell Biol. 2018 Mar 29;38(8). pii: e00453-17. doi: 10.1128/MCB.00453-17. Print 2018 Apr 15.

29.

Haemoglobin variants, iron status and anaemia in Sri Lankan adolescents with low red cell indices: A cross sectional survey.

Rodrigo R, Allen A, Manampreri A, Perera L, Fisher CA, Allen S, Weatherall DJ, Premawardhena A.

Blood Cells Mol Dis. 2018 Jul;71:11-15. doi: 10.1016/j.bcmd.2018.01.003. Epub 2018 Feb 2.

PMID:
29409695
30.

Differential in Vitro Biological Action, Coregulator Interactions, and Molecular Dynamic Analysis of Bisphenol A (BPA), BPAF, and BPS Ligand-ERα Complexes.

Li Y, Perera L, Coons LA, Burns KA, Tyler Ramsey J, Pelch KE, Houtman R, van Beuningen R, Teng CT, Korach KS.

Environ Health Perspect. 2018 Jan 31;126(1):017012. doi: 10.1289/EHP2505.

31.

Iron status and anaemia in Sri Lankan secondary school children: A cross-sectional survey.

Allen A, Allen S, Rodrigo R, Perera L, Shao W, Li C, Wang D, Olivieri N, Weatherall DJ, Premawardhena A.

PLoS One. 2017 Nov 20;12(11):e0188110. doi: 10.1371/journal.pone.0188110. eCollection 2017.

32.

Syntheses of Amino-Substituted Iridabenzofurans and Subsequent Selective N-Functionalisation.

Frogley BJ, Perera LC, Wright LJ.

Chemistry. 2018 Mar 20;24(17):4304-4309. doi: 10.1002/chem.201704677. Epub 2017 Dec 4.

PMID:
29114951
33.

Identification of drivers for the metamorphic transition of HIV-1 reverse transcriptase.

Zheng X, Mueller GA, Kim K, Perera L, DeRose EF, London RE.

Biochem J. 2017 Sep 24;474(19):3321-3338. doi: 10.1042/BCJ20170480.

34.

Binding of bisphenol A, bisphenol AF, and bisphenol S on the androgen receptor: Coregulator recruitment and stimulation of potential interaction sites.

Perera L, Li Y, Coons LA, Houtman R, van Beuningen R, Goodwin B, Auerbach SS, Teng CT.

Toxicol In Vitro. 2017 Oct;44:287-302. doi: 10.1016/j.tiv.2017.07.020. Epub 2017 Jul 24.

35.

Chimeric antigen receptor modified T cells that target chemokine receptor CCR4 as a therapeutic modality for T-cell malignancies.

Perera LP, Zhang M, Nakagawa M, Petrus MN, Maeda M, Kadin ME, Waldmann TA, Perera PY.

Am J Hematol. 2017 Sep;92(9):892-901. doi: 10.1002/ajh.24794. Epub 2017 Jun 5.

36.

White Paper AGA: The Impact of Mental and Psychosocial Factors on the Care of Patients With Inflammatory Bowel Disease.

Szigethy EM, Allen JI, Reiss M, Cohen W, Perera LP, Brillstein L, Cross RK, Schwartz DA, Kosinski LR, Colton JB, LaRusso E, Atreja A, Regueiro MD.

Clin Gastroenterol Hepatol. 2017 Jul;15(7):986-997. doi: 10.1016/j.cgh.2017.02.037. Epub 2017 Mar 12. Review.

PMID:
28300693
37.

Phosphorylated Nuclear Receptor CAR Forms a Homodimer To Repress Its Constitutive Activity for Ligand Activation.

Shizu R, Osabe M, Perera L, Moore R, Sueyoshi T, Negishi M.

Mol Cell Biol. 2017 May 2;37(10). pii: e00649-16. doi: 10.1128/MCB.00649-16. Print 2017 May 15.

38.

Revealing the role of the product metal in DNA polymerase β catalysis.

Perera L, Freudenthal BD, Beard WA, Pedersen LG, Wilson SH.

Nucleic Acids Res. 2017 Mar 17;45(5):2736-2745. doi: 10.1093/nar/gkw1363.

39.

Dengue fever may mislead the surgeons when it presents as an acute abdomen.

Jayasundara B, Perera L, de Silva A.

Asian Pac J Trop Med. 2017 Jan;10(1):15-19. doi: 10.1016/j.apjtm.2016.12.010. Epub 2016 Dec 28.

40.

An Ancient Family of RNA-Binding Proteins: Still Important!

Wells ML, Perera L, Blackshear PJ.

Trends Biochem Sci. 2017 Apr;42(4):285-296. doi: 10.1016/j.tibs.2016.12.003. Epub 2017 Jan 14. Review.

41.

Estimation of provider cost and the out of pocket expenditure for cataract surgery at a base hospital

Perera C, De Silva D, Perera L R.

Ceylon Med J. 2016 Dec 30;61(4):200. doi: 10.4038/cmj.v61i4.8395. No abstract available.

42.

Hiding in Plain Sight: The Bimetallic Magnesium Covalent Bond in Enzyme Active Sites.

Perera L, Beard WA, Pedersen LG, Wilson SH.

Inorg Chem. 2017 Jan 3;56(1):313-320. doi: 10.1021/acs.inorgchem.6b02189. Epub 2016 Dec 15.

43.

FICD acts bifunctionally to AMPylate and de-AMPylate the endoplasmic reticulum chaperone BiP.

Preissler S, Rato C, Perera L, Saudek V, Ron D.

Nat Struct Mol Biol. 2017 Jan;24(1):23-29. doi: 10.1038/nsmb.3337. Epub 2016 Dec 5.

44.

The evolutionary and clinical implications of the uneven distribution of the frequency of the inherited haemoglobin variants over short geographical distances.

Premawardhena A, Allen A, Piel F, Fisher C, Perera L, Rodrigo R, Goonathilaka G, Ramees L, Peto T, Olivieri N, Weatherall D.

Br J Haematol. 2017 Feb;176(3):475-484. doi: 10.1111/bjh.14437. Epub 2016 Nov 29.

45.

Hepcidin detects iron deficiency in Sri Lankan adolescents with a high burden of hemoglobinopathy: A diagnostic test accuracy study.

Wray K, Allen A, Evans E, Fisher C, Premawardhena A, Perera L, Rodrigo R, Goonathilaka G, Ramees L, Webster C, Armitage AE, Prentice AM, Weatherall DJ, Drakesmith H, Pasricha SR.

Am J Hematol. 2017 Feb;92(2):196-203. doi: 10.1002/ajh.24617.

46.

Largazole Analogues Embodying Radical Changes in the Depsipeptide Ring: Development of a More Selective and Highly Potent Analogue.

Almaliti J, Al-Hamashi AA, Negmeldin AT, Hanigan CL, Perera L, Pflum MK, Casero RA Jr, Tillekeratne LM.

J Med Chem. 2016 Dec 8;59(23):10642-10660. Epub 2016 Nov 21.

47.

Reversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2.

Schellenberg MJ, Perera L, Strom CN, Waters CA, Monian B, Appel CD, Vilas CK, Williams JG, Ramsden DA, Williams RS.

Nucleic Acids Res. 2016 May 5;44(8):3829-44. doi: 10.1093/nar/gkw228. Epub 2016 Apr 8.

48.

GATA3-dependent cellular reprogramming requires activation-domain dependent recruitment of a chromatin remodeler.

Takaku M, Grimm SA, Shimbo T, Perera L, Menafra R, Stunnenberg HG, Archer TK, Machida S, Kurumizaka H, Wade PA.

Genome Biol. 2016 Feb 27;17:36. doi: 10.1186/s13059-016-0897-0.

49.

Serological, genomic and structural analyses of the major mite allergen Der p 23.

Mueller GA, Randall TA, Glesner J, Pedersen LC, Perera L, Edwards LL, DeRose EF, Chapman MD, London RE, Pomés A.

Clin Exp Allergy. 2016 Feb;46(2):365-76. doi: 10.1111/cea.12680.

50.

Co-expression of Interleukin-15 Enhances the Protective Immune Responses Induced by Immunization with a Murine Malaria MVA-Based Vaccine Encoding the Circumsporozoite Protein.

Parra M, Liu X, Derrick SC, Yang A, Molina-Cruz A, Barillas-Mury C, Zheng H, Thao Pham P, Sedegah M, Belmonte A, Litilit DD, Waldmann TA, Kumar S, Morris SL, Perera LP.

PLoS One. 2015 Oct 27;10(10):e0141141. doi: 10.1371/journal.pone.0141141. eCollection 2015.

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