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Items: 9


Reversion of down-regulation of intestinal multidrug resistance-associated protein 2 in fructose-fed rats by geraniol and vitamin C: Potential role of inflammatory response and oxidative stress.

Zecchinati F, Barranco MM, Arana MR, Tocchetti GN, Domínguez CJ, Perdomo VG, Ruiz ML, Mottino AD, García F, Villanueva SSM.

J Nutr Biochem. 2019 Jun;68:7-15. doi: 10.1016/j.jnutbio.2019.03.002. Epub 2019 Mar 19.


Intestinal multidrug resistance-associated protein 2 is down-regulated in fructose-fed rats.

Londero AS, Arana MR, Perdomo VG, Tocchetti GN, Zecchinati F, Ghanem CI, Ruiz ML, Rigalli JP, Mottino AD, García F, Villanueva SSM.

J Nutr Biochem. 2017 Feb;40:178-186. doi: 10.1016/j.jnutbio.2016.11.002. Epub 2016 Nov 9.


Up-regulation of ATP-binding cassette transporters in the THP-1 human macrophage cell line by the antichagasic benznidazole.

Perdomo VG, Rigalli JP, Luquita MG, Pellegrino JM, Ruiz ML, Catania VA.

Mem Inst Oswaldo Cruz. 2016 Nov;111(11):707-711. doi: 10.1590/0074-02760160080. Epub 2016 Oct 24.


The trypanocidal benznidazole promotes adaptive response to oxidative injury: Involvement of the nuclear factor-erythroid 2-related factor-2 (Nrf2) and multidrug resistance associated protein 2 (MRP2).

Rigalli JP, Perdomo VG, Ciriaci N, Francés DE, Ronco MT, Bataille AM, Ghanem CI, Ruiz ML, Manautou JE, Catania VA.

Toxicol Appl Pharmacol. 2016 Aug 1;304:90-8. doi: 10.1016/j.taap.2016.05.007. Epub 2016 May 12.


Regulation of expression and activity of multidrug resistance proteins MRP2 and MDR1 by estrogenic compounds in Caco-2 cells. Role in prevention of xenobiotic-induced cytotoxicity.

Arias A, Rigalli JP, Villanueva SS, Ruiz ML, Luquita MG, Perdomo VG, Vore M, Catania VA, Mottino AD.

Toxicology. 2014 Jun 5;320:46-55. doi: 10.1016/j.tox.2014.03.007. Epub 2014 Mar 28.


Modulation of biotransformation systems and ABC transporters by benznidazole in rats.

Perdomo VG, Rigalli JP, Villanueva SS, Ruiz ML, Luquita MG, Echenique CG, Catania VA.

Antimicrob Agents Chemother. 2013 Oct;57(10):4894-902. doi: 10.1128/AAC.02531-12. Epub 2013 Jul 22.


Regulation of biotransformation systems and ABC transporters by benznidazole in HepG2 cells: involvement of pregnane X-receptor.

Rigalli JP, Perdomo VG, Luquita MG, Villanueva SS, Arias A, Theile D, Weiss J, Mottino AD, Ruiz ML, Catania VA.

PLoS Negl Trop Dis. 2012;6(12):e1951. doi: 10.1371/journal.pntd.0001951. Epub 2012 Dec 13.


Effect of glucagon-like peptide 2 on hepatic, renal, and intestinal disposition of 1-chloro-2,4-dinitrobenzene.

Villanueva SS, Perdomo VG, Ruiz ML, Rigalli JP, Arias A, Luquita MG, Vore M, Catania VA, Mottino AD.

Drug Metab Dispos. 2012 Jul;40(7):1252-8. doi: 10.1124/dmd.111.044339. Epub 2012 Mar 27.


Pregnane X receptor mediates the induction of P-glycoprotein by spironolactone in HepG2 cells.

Rigalli JP, Ruiz ML, Perdomo VG, Villanueva SS, Mottino AD, Catania VA.

Toxicology. 2011 Jul 11;285(1-2):18-24. doi: 10.1016/j.tox.2011.03.015. Epub 2011 Apr 1.


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