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Items: 1 to 50 of 53

1.

Pancreatic (pro)enzymes treatment suppresses BXPC-3 pancreatic Cancer Stem Cell subpopulation and impairs tumour engrafting.

Hernández-Camarero P, López-Ruiz E, Griñán-Lisón C, García MÁ, Chocarro-Wrona C, Marchal JA, Kenyon J, Perán M.

Sci Rep. 2019 Aug 6;9(1):11359. doi: 10.1038/s41598-019-47837-7.

2.

A soft 3D polyacrylate hydrogel recapitulates the cartilage niche and allows growth-factor free tissue engineering of human articular cartilage.

Jiménez G, Venkateswaran S, López-Ruiz E, Perán M, Pernagallo S, Díaz-Monchón JJ, Canadas RF, Antich C, Oliveira JM, Callanan A, Walllace R, Reis RL, Montañez E, Carrillo E, Bradley M, Marchal JA.

Acta Biomater. 2019 May;90:146-156. doi: 10.1016/j.actbio.2019.03.040. Epub 2019 Mar 22.

PMID:
30910621
3.

Volume-by-volume bioprinting of chondrocytes-alginate bioinks in high temperature thermoplastic scaffolds for cartilage regeneration.

Baena JM, Jiménez G, López-Ruiz E, Antich C, Griñán-Lisón C, Perán M, Gálvez-Martín P, Marchal JA.

Exp Biol Med (Maywood). 2019 Jan;244(1):13-21. doi: 10.1177/1535370218821128. Epub 2019 Jan 10.

PMID:
30630373
4.

Therapeutic strategies for skin regeneration based on biomedical substitutes.

Chocarro-Wrona C, López-Ruiz E, Perán M, Gálvez-Martín P, Marchal JA.

J Eur Acad Dermatol Venereol. 2019 Mar;33(3):484-496. doi: 10.1111/jdv.15391. Epub 2019 Feb 22. Review.

PMID:
30520159
5.

Revisiting the dynamic cancer stem cell model: Importance of tumour edges.

Hernández-Camarero P, Jiménez G, López-Ruiz E, Barungi S, Marchal JA, Perán M.

Crit Rev Oncol Hematol. 2018 Nov;131:35-45. doi: 10.1016/j.critrevonc.2018.08.004. Epub 2018 Aug 28. Review.

PMID:
30293704
6.

Mesenchymal stem cell's secretome promotes selective enrichment of cancer stem-like cells with specific cytogenetic profile.

Jiménez G, Hackenberg M, Catalina P, Boulaiz H, Griñán-Lisón C, García MÁ, Perán M, López-Ruiz E, Ramírez A, Morata-Tarifa C, Carrasco E, Aguilera M, Marchal JA.

Cancer Lett. 2018 Aug 10;429:78-88. doi: 10.1016/j.canlet.2018.04.042. Epub 2018 May 5.

PMID:
29733965
7.

Impact of TGF-β family-related growth factors on chondrogenic differentiation of adipose-derived stem cells isolated from lipoaspirates and infrapatellar fat pads of osteoarthritic patients.

López-Ruiz E, Jiménez G, Kwiatkowski W, Montañez E, Arrebola F, Carrillo E, Choe S, Marchal JA, Perán M.

Eur Cell Mater. 2018 Apr 13;35:209-224. doi: 10.22203/eCM.v035a15.

8.

A formulation of pancreatic pro-enzymes provides potent anti-tumour efficacy: a pilot study focused on pancreatic and ovarian cancer.

Perán M, López-Ruiz E, García MÁ, Nadaraia-Hoke S, Brandt R, Marchal JA, Kenyon J.

Sci Rep. 2017 Oct 25;7(1):13998. doi: 10.1038/s41598-017-14571-x.

9.

Biofunctional Ionic-Doped Calcium Phosphates: Silk Fibroin Composites for Bone Tissue Engineering Scaffolding.

Pina S, Canadas RF, Jiménez G, Perán M, Marchal JA, Reis RL, Oliveira JM.

Cells Tissues Organs. 2017;204(3-4):150-163. doi: 10.1159/000469703. Epub 2017 Aug 12.

PMID:
28803246
10.

Clinical and therapeutic potential of protein kinase PKR in cancer and metabolism.

Garcia-Ortega MB, Lopez GJ, Jimenez G, Garcia-Garcia JA, Conde V, Boulaiz H, Carrillo E, Perán M, Marchal JA, Garcia MA.

Expert Rev Mol Med. 2017 Jul 20;19:e9. doi: 10.1017/erm.2017.11. Review.

PMID:
28724458
11.

Poly(ethylmethacrylate-co-diethylaminoethyl acrylate) coating improves endothelial re-population, bio-mechanical and anti-thrombogenic properties of decellularized carotid arteries for blood vessel replacement.

López-Ruiz E, Venkateswaran S, Perán M, Jiménez G, Pernagallo S, Díaz-Mochón JJ, Tura-Ceide O, Arrebola F, Melchor J, Soto J, Rus G, Real PJ, Diaz-Ricart M, Conde-González A, Bradley M, Marchal JA.

Sci Rep. 2017 Mar 24;7(1):407. doi: 10.1038/s41598-017-00294-6.

12.

Knee Viscosupplementation: Cost-Effectiveness Analysis between Stabilized Hyaluronic Acid in a Single Injection versus Five Injections of Standard Hyaluronic Acid.

Estades-Rubio FJ, Reyes-Martín A, Morales-Marcos V, García-Piriz M, García-Vera JJ, Perán M, Marchal JA, Montañez-Heredia E.

Int J Mol Sci. 2017 Mar 17;18(3). pii: E658. doi: 10.3390/ijms18030658.

13.

Validation of suitable normalizers for miR expression patterns analysis covering tumour heterogeneity.

Morata-Tarifa C, Picon-Ruiz M, Griñan-Lison C, Boulaiz H, Perán M, Garcia MA, Marchal JA.

Sci Rep. 2017 Jan 4;7:39782. doi: 10.1038/srep39782.

14.

Cancer suicide gene therapy: a patent review.

Navarro SA, Carrillo E, Griñán-Lisón C, Martín A, Perán M, Marchal JA, Boulaiz H.

Expert Opin Ther Pat. 2016 Sep;26(9):1095-104. doi: 10.1080/13543776.2016.1211640. Epub 2016 Jul 20. Review.

PMID:
27424657
15.

Intra-Articular Injections of Platelet-Rich Plasma versus Hyaluronic Acid in the Treatment of Osteoarthritic Knee Pain: A Randomized Clinical Trial in the Context of the Spanish National Health Care System.

Montañez-Heredia E, Irízar S, Huertas PJ, Otero E, Del Valle M, Prat I, Díaz-Gallardo MS, Perán M, Marchal JA, Hernandez-Lamas Mdel C.

Int J Mol Sci. 2016 Jul 2;17(7). pii: E1064. doi: 10.3390/ijms17071064.

16.

Polymers, scaffolds and bioactive molecules with therapeutic properties in osteochondral pathologies: what's new?

López-Ruiz E, Jiménez G, García MÁ, Antich C, Boulaiz H, Marchal JA, Perán M.

Expert Opin Ther Pat. 2016 Aug;26(8):877-90. doi: 10.1080/13543776.2016.1203903. Epub 2016 Jul 8. Review.

PMID:
27337937
17.

Activin A/BMP2 chimera AB235 drives efficient redifferentiation of long term cultured autologous chondrocytes.

Jiménez G, López-Ruiz E, Kwiatkowski W, Montañez E, Arrebola F, Carrillo E, Gray PC, Izpisua Belmonte JC, Choe S, Perán M, Marchal JA.

Sci Rep. 2015 Nov 13;5:16400. doi: 10.1038/srep16400.

18.

5-Fluorouracil derivatives: a patent review (2012 - 2014).

Carrillo E, Navarro SA, Ramírez A, García MÁ, Griñán-Lisón C, Perán M, Marchal JA.

Expert Opin Ther Pat. 2015;25(10):1131-44. doi: 10.1517/13543776.2015.1056736. Epub 2015 Jul 13. Review.

PMID:
26165922
19.

Brown adipose tissue and novel therapeutic approaches to treat metabolic disorders.

Roman S, Agil A, Peran M, Alvaro-Galue E, Ruiz-Ojeda FJ, Fernández-Vázquez G, Marchal JA.

Transl Res. 2015 Apr;165(4):464-79. doi: 10.1016/j.trsl.2014.11.002. Epub 2014 Nov 8. Review.

PMID:
25433289
20.

EMT and EGFR in CTCs cytokeratin negative non-metastatic breast cancer.

Serrano MJ, Ortega FG, Alvarez-Cubero MJ, Nadal R, Sanchez-Rovira P, Salido M, Rodríguez M, García-Puche JL, Delgado-Rodriguez M, Solé F, García MA, Perán M, Rosell R, Marchal JA, Lorente JA.

Oncotarget. 2014 Sep 15;5(17):7486-97.

21.

Emergency nursing in Spain.

Franco LF, Perán MÁ.

J Emerg Nurs. 2014 Nov;40(6):627-8. doi: 10.1016/j.jen.2014.08.003. Epub 2014 Sep 18. No abstract available.

PMID:
25241634
22.

Cardiomyogenic differentiation potential of human endothelial progenitor cells isolated from patients with myocardial infarction.

López-Ruiz E, Perán M, Picón-Ruiz M, García MA, Carrillo E, Jiménez-Navarro M, Hernández MC, Prat I, De Teresa E, Marchal JA.

Cytotherapy. 2014 Sep;16(9):1229-37. doi: 10.1016/j.jcyt.2014.05.012. Epub 2014 Jun 23.

PMID:
24969968
23.

HER2-signaling pathway, JNK and ERKs kinases, and cancer stem-like cells are targets of Bozepinib small compound.

Ramírez A, Boulaiz H, Morata-Tarifa C, Perán M, Jiménez G, Picon-Ruiz M, Agil A, Cruz-López O, Conejo-García A, Campos JM, Sánchez A, García MA, Marchal JA.

Oncotarget. 2014 Jun 15;5(11):3590-606.

24.

The impact of PKR activation: from neurodegeneration to cancer.

Marchal JA, Lopez GJ, Peran M, Comino A, Delgado JR, García-García JA, Conde V, Aranda FM, Rivas C, Esteban M, Garcia MA.

FASEB J. 2014 May;28(5):1965-74. doi: 10.1096/fj.13-248294. Epub 2014 Feb 12. Review.

PMID:
24522206
25.

Designer nodal/BMP2 chimeras mimic nodal signaling, promote chondrogenesis, and reveal a BMP2-like structure.

Esquivies L, Blackler A, Peran M, Rodriguez-Esteban C, Izpisua Belmonte JC, Booker E, Gray PC, Ahn C, Kwiatkowski W, Choe S.

J Biol Chem. 2014 Jan 17;289(3):1788-97. doi: 10.1074/jbc.M113.529180. Epub 2013 Dec 5.

26.

Cellular extracts from post-mortem human cardiac tissue direct cardiomyogenic differentiation of human adipose tissue-derived stem cells.

Perán M, López-Ruiz E, González-Herrera L, Bustamante M, Valenzuela A, Marchal JA.

Cytotherapy. 2013 Dec;15(12):1541-8. doi: 10.1016/j.jcyt.2013.06.016.

PMID:
24199593
27.

Bozepinib, a novel small antitumor agent, induces PKR-mediated apoptosis and synergizes with IFNα triggering apoptosis, autophagy and senescence.

Marchal JA, Carrasco E, Ramirez A, Jiménez G, Olmedo C, Peran M, Agil A, Conejo-García A, Cruz-López O, Campos JM, García MÁ.

Drug Des Devel Ther. 2013 Oct 29;7:1301-13. doi: 10.2147/DDDT.S51354. eCollection 2013.

28.

In vitro treatment of carcinoma cell lines with pancreatic (pro)enzymes suppresses the EMT programme and promotes cell differentiation.

Perán M, Marchal JA, García MA, Kenyon J, Tosh D.

Cell Oncol (Dordr). 2013 Jul;36(4):289-301. doi: 10.1007/s13402-013-0134-8. Epub 2013 May 16.

PMID:
23677639
29.

In vitro nanoparticle-mediated intracellular delivery into human adipose-derived stem cells.

Sanchez-Martin R, Cano-Cortés V, Marchal JA, Perán M.

Methods Mol Biol. 2013;1058:41-7. doi: 10.1007/7651_2013_7.

PMID:
23592034
30.

How Can Nanotechnology Help to Repair the Body? Advances in Cardiac, Skin, Bone, Cartilage and Nerve Tissue Regeneration.

Perán M, García MA, Lopez-Ruiz E, Jiménez G, Marchal JA.

Materials (Basel). 2013 Mar 28;6(4):1333-1359. doi: 10.3390/ma6041333. Review.

31.

Activin/BMP2 chimeric ligands direct adipose-derived stem cells to chondrogenic differentiation.

Peran M, Ruiz S, Kwiatkowski W, Marchal JA, Yang SL, Aranega A, Choe S, Izpisua Belmonte JC.

Stem Cell Res. 2013 May;10(3):464-76. doi: 10.1016/j.scr.2013.02.002. Epub 2013 Feb 12.

32.

Chondrocytes extract from patients with osteoarthritis induces chondrogenesis in infrapatellar fat pad-derived stem cells.

López-Ruiz E, Perán M, Cobo-Molinos J, Jiménez G, Picón M, Bustamante M, Arrebola F, Hernández-Lamas MC, Delgado-Martínez AD, Montañez E, Marchal JA.

Osteoarthritis Cartilage. 2013 Jan;21(1):246-58. doi: 10.1016/j.joca.2012.10.007. Epub 2012 Oct 18.

33.

Functionalized nanostructures with application in regenerative medicine.

Perán M, García MA, López-Ruiz E, Bustamante M, Jiménez G, Madeddu R, Marchal JA.

Int J Mol Sci. 2012;13(3):3847-86. doi: 10.3390/ijms13033847. Epub 2012 Mar 22. Review.

34.

[Factors influencing mobilisation of endothelial progenitor cells and angiogenic cytokines after an extensive acute myocardial infarction].

Domínguez-Franco A, González FJ, Rodríguez-Losada N, Marchal JA, Cabrera-Bueno F, Carrillo E, Gómez-Doblas JJ, Perán M, Alonso-Briales JH, Jiménez-Navarro MF, Aránega A, De Teresa Galván E; Red de Investigación Cardiovascular (RECAVA).

Med Clin (Barc). 2012 Apr 21;138(10):415-21. doi: 10.1016/j.medcli.2011.05.031. Epub 2011 Dec 23. Spanish.

PMID:
22197368
35.

gef gene expression in MCF-7 breast cancer cells is associated with a better prognosis and induction of apoptosis by p53-mediated signaling pathway.

Boulaiz H, Alvarez PJ, Prados J, Marchal J, Melguizo C, Carrillo E, Peran M, Rodríguez F, Ramírez A, Ortíz R, Aránega A.

Int J Mol Sci. 2011;12(11):7445-58. doi: 10.3390/ijms12117445. Epub 2011 Oct 31.

36.

[Transperitoneal laparoscopic adrenalectomy].

Virseda JA, Ruiz-Mondéjar R, Donate MJ, Carrión P, Martínez-Ruiz J, Martínez-Sanchiz C, Perán M, Pastor H.

Actas Urol Esp. 2011 Oct;35(9):546-51. doi: 10.1016/j.acuro.2011.01.020. Epub 2011 Jun 22. Spanish.

PMID:
21700366
37.

Nanomedicine: application areas and development prospects.

Boulaiz H, Alvarez PJ, Ramirez A, Marchal JA, Prados J, Rodríguez-Serrano F, Perán M, Melguizo C, Aranega A.

Int J Mol Sci. 2011;12(5):3303-21. doi: 10.3390/ijms12053303. Epub 2011 May 19. Review.

38.

Purification and long-term expansion of multipotent endothelial-like cells with potential cardiovascular regeneration.

Marchal JA, Picón M, Perán M, Bueno C, Jiménez-Navarro M, Carrillo E, Boulaiz H, Rodríguez N, Álvarez P, Menendez P, de Teresa E, Aránega A.

Stem Cells Dev. 2012 Mar 1;21(4):562-74. doi: 10.1089/scd.2011.0072. Epub 2011 Jun 17.

PMID:
21542697
39.

Influence of preinfarction angina on the release kinetics of endothelial progenitor cells and cytokines during the week after infarction.

Jiménez-Navarro MF, Caballero-Borrego J, Rodriguez-Losada N, Cabrera-Bueno F, Marchal JA, Estebaranz J, Muñoz-García A, Perán M, Pérez R, Ramírez G, Hernández-García JM, Aránega A, de Teresa Galván E.

Eur J Clin Invest. 2011 Nov;41(11):1220-6. doi: 10.1111/j.1365-2362.2011.02529.x. Epub 2011 Apr 25.

PMID:
21517829
40.

Transdifferentiation: why and how?

Perán M, Marchal JA, Rodríguez-Serrano F, Alvarez P, Aránega A.

Cell Biol Int. 2011 Apr;35(4):373-9. doi: 10.1042/CBI20100445. Review.

PMID:
21413928
41.

Ultrastructural and molecular analyzes of insulin-producing cells induced from human hepatoma cells.

Perán M, Sánchez-Ferrero A, Tosh D, Marchal JA, Lopez E, Alvarez P, Boulaiz H, Rodríguez-Serrano F, Aranega A.

Cytotherapy. 2011 Feb;13(2):193-200. doi: 10.3109/14653249.2010.501791. Epub 2010 Jul 22.

PMID:
20662611
42.

Promotion of human adipose-derived stem cell proliferation mediated by exogenous nucleosides.

Rodríguez-Serrano F, Alvarez P, Caba O, Picón M, Marchal JA, Perán M, Prados J, Melguizo C, Rama AR, Boulaiz H, Aránega A.

Cell Biol Int. 2010 Sep;34(9):917-24. doi: 10.1042/CBI20100227.

PMID:
20522021
43.

Human cardiac tissue induces transdifferentiation of adult stem cells towards cardiomyocytes.

Perán M, Marchal JA, López E, Jiménez-Navarro M, Boulaiz H, Rodríguez-Serrano F, Carrillo E, Sánchez-Espin G, de Teresa E, Tosh D, Aranega A.

Cytotherapy. 2010 May;12(3):332-7. doi: 10.3109/14653240903548202.

PMID:
20230311
44.

Differentiation of intestinal epithelial cells mediated by cell confluence and/or exogenous nucleoside supplementation.

Rodríguez-Serrano F, Ríos A, Marchal JA, Caba O, Martínez-Amat A, Prados J, Melguizo C, Ortiz R, Perán M, Boulaiz H, Vélez C, Alvarez P, Aránega A.

Cells Tissues Organs. 2010;191(6):478-88. doi: 10.1159/000276593. Epub 2010 Jan 14.

PMID:
20090304
45.

Cell surface immobilization of GABAA Rs in cerebellar granule cells depends on the M3/M4 cytoplasmatic loop of the alpha 1 subunit.

Perán M, Hooper H, Marchal JA, Boulaiz H, Rodríguez-Serrano F, Velez C, Aránega A, Salas R.

Cells Tissues Organs. 2009;189(6):420-4. doi: 10.1159/000159369. Epub 2008 Sep 30.

PMID:
18824838
46.

Tumour malignancy loss and cell differentiation are associated with induction of gef gene in human melanoma cells.

Boulaiz H, Prados J, Melguizo C, Marchal JA, Carrillo E, Peran M, Rodríguez-Serrano F, Martínez-Amat A, Caba O, Hita F, Concha A, Aránega A.

Br J Dermatol. 2008 Aug;159(2):370-8. doi: 10.1111/j.1365-2133.2008.08688.x. Epub 2008 Jun 28.

PMID:
18565182
47.

5-fluorouracil derivatives induce differentiation mediated by tubulin and HLA class I modulation.

Marchal JA, Boulaiz H, Rodríguez-Serrano F, Peran M, Carrillo E, Vélez C, Domínguez J, Gómez-Vidal JA, Campos J, Gallo MA, Espinosa A, Aránega A.

Med Chem. 2007 May;3(3):233-9.

PMID:
17504194
48.

Stem cells in the adult pancreas and liver.

Burke ZD, Thowfeequ S, Peran M, Tosh D.

Biochem J. 2007 Jun 1;404(2):169-78. Review.

49.

Exogenous nucleosides modulate proliferation of rat intestinal epithelial IEC-6 cells.

Rodríguez-Serrano F, Marchal JA, Ríos A, Martínez-Amat A, Boulaiz H, Prados J, Perán M, Caba O, Carrillo E, Hita F, Aránega A.

J Nutr. 2007 Apr;137(4):879-84.

PMID:
17374648
50.

The M3/M4 cytoplasmic loop of the alpha1 subunit restricts GABAARs lateral mobility: a study using fluorescence recovery after photobleaching.

Perán M, Hooper H, Boulaiz H, Marchal JA, Aránega A, Salas R.

Cell Motil Cytoskeleton. 2006 Dec;63(12):747-57.

PMID:
17029290

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