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Items: 13

1.

Quantification of Etoposide Hypersensitivity: A Sensitive, Functional Method for Assessing Pluripotent Stem Cell Quality.

Secreto FJ, Li X, Smith AJ, Bruinsma ES, Perales-Clemente E, Oommen S, Hawse G, Hrstka SCL, Arendt BK, Brandt EB, Wigle DA, Nelson TJ.

Stem Cells Transl Med. 2017 Oct;6(10):1829-1839. doi: 10.1002/sctm.17-0116. Epub 2017 Sep 19.

2.

Natural underlying mtDNA heteroplasmy as a potential source of intra-person hiPSC variability.

Perales-Clemente E, Cook AN, Evans JM, Roellinger S, Secreto F, Emmanuele V, Oglesbee D, Mootha VK, Hirano M, Schon EA, Terzic A, Nelson TJ.

EMBO J. 2016 Sep 15;35(18):1979-90. doi: 10.15252/embj.201694892. Epub 2016 Jul 19.

3.

The CoQH2/CoQ Ratio Serves as a Sensor of Respiratory Chain Efficiency.

Guarás A, Perales-Clemente E, Calvo E, Acín-Pérez R, Loureiro-Lopez M, Pujol C, Martínez-Carrascoso I, Nuñez E, García-Marqués F, Rodríguez-Hernández MA, Cortés A, Diaz F, Pérez-Martos A, Moraes CT, Fernández-Silva P, Trifunovic A, Navas P, Vazquez J, Enríquez JA.

Cell Rep. 2016 Apr 5;15(1):197-209. doi: 10.1016/j.celrep.2016.03.009. Epub 2016 Mar 24.

4.

Metabolic regulation of redox status in stem cells.

Perales-Clemente E, Folmes CD, Terzic A.

Antioxid Redox Signal. 2014 Oct 10;21(11):1648-59. doi: 10.1089/ars.2014.6000. Epub 2014 Sep 4. Review.

5.

Spot14/Mig12 heterocomplex sequesters polymerization and restrains catalytic function of human acetyl-CoA carboxylase 2.

Park S, Hwang IW, Makishima Y, Perales-Clemente E, Kato T, Niederländer NJ, Park EY, Terzic A.

J Mol Recognit. 2013 Dec;26(12):679-88. doi: 10.1002/jmr.2313.

6.

Mitochondrial cristae shape determines respiratory chain supercomplexes assembly and respiratory efficiency.

Cogliati S, Frezza C, Soriano ME, Varanita T, Quintana-Cabrera R, Corrado M, Cipolat S, Costa V, Casarin A, Gomes LC, Perales-Clemente E, Salviati L, Fernandez-Silva P, Enriquez JA, Scorrano L.

Cell. 2013 Sep 26;155(1):160-71. doi: 10.1016/j.cell.2013.08.032. Epub 2013 Sep 19.

7.

Supercomplex assembly determines electron flux in the mitochondrial electron transport chain.

Lapuente-Brun E, Moreno-Loshuertos R, Acín-Pérez R, Latorre-Pellicer A, Colás C, Balsa E, Perales-Clemente E, Quirós PM, Calvo E, Rodríguez-Hernández MA, Navas P, Cruz R, Carracedo Á, López-Otín C, Pérez-Martos A, Fernández-Silva P, Fernández-Vizarra E, Enríquez JA.

Science. 2013 Jun 28;340(6140):1567-70. doi: 10.1126/science.1230381.

PMID:
23812712
8.

Disease-causing mitochondrial heteroplasmy segregated within induced pluripotent stem cell clones derived from a patient with MELAS.

Folmes CD, Martinez-Fernandez A, Perales-Clemente E, Li X, McDonald A, Oglesbee D, Hrstka SC, Perez-Terzic C, Terzic A, Nelson TJ.

Stem Cells. 2013 Jul;31(7):1298-308. doi: 10.1002/stem.1389.

9.

NDUFA4 is a subunit of complex IV of the mammalian electron transport chain.

Balsa E, Marco R, Perales-Clemente E, Szklarczyk R, Calvo E, Landázuri MO, Enríquez JA.

Cell Metab. 2012 Sep 5;16(3):378-86. doi: 10.1016/j.cmet.2012.07.015. Epub 2012 Aug 16.

10.

Induction of the mitochondrial NDUFA4L2 protein by HIF-1α decreases oxygen consumption by inhibiting Complex I activity.

Tello D, Balsa E, Acosta-Iborra B, Fuertes-Yebra E, Elorza A, Ordóñez Á, Corral-Escariz M, Soro I, López-Bernardo E, Perales-Clemente E, Martínez-Ruiz A, Enríquez JA, Aragonés J, Cadenas S, Landázuri MO.

Cell Metab. 2011 Dec 7;14(6):768-79. doi: 10.1016/j.cmet.2011.10.008. Epub 2011 Nov 17.

11.

Allotopic expression of mitochondrial-encoded genes in mammals: achieved goal, undemonstrated mechanism or impossible task?

Perales-Clemente E, Fernández-Silva P, Acín-Pérez R, Pérez-Martos A, Enríquez JA.

Nucleic Acids Res. 2011 Jan;39(1):225-34. doi: 10.1093/nar/gkq769. Epub 2010 Sep 7.

12.

Five entry points of the mitochondrially encoded subunits in mammalian complex I assembly.

Perales-Clemente E, Fernández-Vizarra E, Acín-Pérez R, Movilla N, Bayona-Bafaluy MP, Moreno-Loshuertos R, Pérez-Martos A, Fernández-Silva P, Enríquez JA.

Mol Cell Biol. 2010 Jun;30(12):3038-47. doi: 10.1128/MCB.00025-10. Epub 2010 Apr 12.

13.

Restoration of electron transport without proton pumping in mammalian mitochondria.

Perales-Clemente E, Bayona-Bafaluy MP, Pérez-Martos A, Barrientos A, Fernández-Silva P, Enriquez JA.

Proc Natl Acad Sci U S A. 2008 Dec 2;105(48):18735-9. doi: 10.1073/pnas.0810518105. Epub 2008 Nov 19.

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