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Items: 18


Proof of concept for AAV2/5-mediated gene therapy in iPSC-derived retinal pigment epithelium of a choroideremia patient.

Cereso N, Pequignot MO, Robert L, Becker F, De Luca V, Nabholz N, Rigau V, De Vos J, Hamel CP, Kalatzis V.

Mol Ther Methods Clin Dev. 2014 Apr 2;1:14011. doi: 10.1038/mtm.2014.11. eCollection 2014.


Fatp1 deficiency affects retinal light response and dark adaptation, and induces age-related alterations.

Chekroud K, Guillou L, Grégoire S, Ducharme G, Brun E, Cazevieille C, Bretillon L, Hamel CP, Brabet P, Pequignot MO.

PLoS One. 2012;7(11):e50231. doi: 10.1371/journal.pone.0050231. Epub 2012 Nov 16.


The retinal pigment epithelium undergoes massive apoptosis during early differentiation and pigmentation of the optic cup.

Pequignot MO, Provost AC, Sallé S, Menasche M, Saule S, Jaïs JP, Abitbol M.

Mol Vis. 2011 Apr 20;17:989-96.


Simple and efficient: validation of a cotton wick electrode for animal electroretinography.

Chekroud K, Arndt C, Basset D, Hamel CP, Brabet P, Pequignot MO.

Ophthalmic Res. 2011;45(4):174-9. doi: 10.1159/000321118. Epub 2010 Nov 4. Erratum in: Ophthalmic Res. 2011;46(2):91.


FATP1 inhibits 11-cis retinol formation via interaction with the visual cycle retinoid isomerase RPE65 and lecithin:retinol acyltransferase.

Guignard TJ, Jin M, Pequignot MO, Li S, Chassigneux Y, Chekroud K, Guillou L, Richard E, Hamel CP, Brabet P.

J Biol Chem. 2010 Jun 11;285(24):18759-68. doi: 10.1074/jbc.M109.064329. Epub 2010 Mar 31.


Best1 is a gene regulated by nerve injury and required for Ca2+-activated Cl- current expression in axotomized sensory neurons.

Boudes M, Sar C, Menigoz A, Hilaire C, Péquignot MO, Kozlenkov A, Marmorstein A, Carroll P, Valmier J, Scamps F.

J Neurosci. 2009 Aug 12;29(32):10063-71. doi: 10.1523/JNEUROSCI.1312-09.2009.


Enrichment of non-synchronized cells in the G1, S and G2 phases of the cell cycle for the study of apoptosis.

Coquelle A, Mouhamad S, Pequignot MO, Braun T, Carvalho G, Vivet S, Métivier D, Castedo M, Kroemer G.

Biochem Pharmacol. 2006 Nov 30;72(11):1396-404. Epub 2006 Apr 29.


Apoptosis regulation in tetraploid cancer cells.

Castedo M, Coquelle A, Vivet S, Vitale I, Kauffmann A, Dessen P, Pequignot MO, Casares N, Valent A, Mouhamad S, Schmitt E, Modjtahedi N, Vainchenker W, Zitvogel L, Lazar V, Garrido C, Kroemer G.

EMBO J. 2006 Jun 7;25(11):2584-95. Epub 2006 May 4.


Cell cycle-dependent cytotoxic and cytostatic effects of bortezomib on colon carcinoma cells.

Coquelle A, Mouhamad S, Pequignot MO, Braun T, Carvalho G, Vivet S, Métivier D, Castedo M, Kroemer G.

Cell Death Differ. 2006 May;13(5):873-5. No abstract available.


Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death.

Casares N, Pequignot MO, Tesniere A, Ghiringhelli F, Roux S, Chaput N, Schmitt E, Hamai A, Hervas-Stubbs S, Obeid M, Coutant F, Métivier D, Pichard E, Aucouturier P, Pierron G, Garrido C, Zitvogel L, Kroemer G.

J Exp Med. 2005 Dec 19;202(12):1691-701.


AIF deficiency compromises oxidative phosphorylation.

Vahsen N, Candé C, Brière JJ, Bénit P, Joza N, Larochette N, Mastroberardino PG, Pequignot MO, Casares N, Lazar V, Feraud O, Debili N, Wissing S, Engelhardt S, Madeo F, Piacentini M, Penninger JM, Schägger H, Rustin P, Kroemer G.

EMBO J. 2004 Nov 24;23(23):4679-89. Epub 2004 Nov 4.


Immune response against dying tumor cells.

Zitvogel L, Casares N, Péquignot MO, Chaput N, Albert ML, Kroemer G.

Adv Immunol. 2004;84:131-79. Review. No abstract available.


Expression of SR-BI receptor and StAR protein in rat ocular tissues.

Provost AC, Péquignot MO, Sainton KM, Gadin S, Sallé S, Marchant D, Hales DB, Abitbol M.

C R Biol. 2003 Sep;326(9):841-51.


Major role of BAX in apoptosis during retinal development and in establishment of a functional postnatal retina.

Péquignot MO, Provost AC, Sallé S, Taupin P, Sainton KM, Marchant D, Martinou JC, Ameisen JC, Jais JP, Abitbol M.

Dev Dyn. 2003 Oct;228(2):231-8.


Intralysosomal cystine accumulation in mice lacking cystinosin, the protein defective in cystinosis.

Cherqui S, Sevin C, Hamard G, Kalatzis V, Sich M, Pequignot MO, Gogat K, Abitbol M, Broyer M, Gubler MC, Antignac C.

Mol Cell Biol. 2002 Nov;22(21):7622-32.


Mutations in the SURF1 gene associated with Leigh syndrome and cytochrome C oxidase deficiency.

Péquignot MO, Dey R, Zeviani M, Tiranti V, Godinot C, Poyau A, Sue C, Di Mauro S, Abitbol M, Marsac C.

Hum Mutat. 2001 May;17(5):374-81.


New splicing-site mutations in the SURF1 gene in Leigh syndrome patients.

Pequignot MO, Desguerre I, Dey R, Tartari M, Zeviani M, Agostino A, Benelli C, Fouque F, Prip-Buus C, Marchant D, Abitbol M, Marsac C.

J Biol Chem. 2001 May 4;276(18):15326-9. Epub 2001 Feb 6.


Homozygous deletion in the coding sequence of the c-mer gene in RCS rats unravels general mechanisms of physiological cell adhesion and apoptosis.

Nandrot E, Dufour EM, Provost AC, Péquignot MO, Bonnel S, Gogat K, Marchant D, Rouillac C, Sépulchre de Condé B, Bihoreau MT, Shaver C, Dufier JL, Marsac C, Lathrop M, Menasche M, Abitbol MM.

Neurobiol Dis. 2000 Dec;7(6 Pt B):586-99.


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