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Items: 36

1.

Neuronal adenosine A2A receptor overexpression is neuroprotective towards 3-nitropropionic acid-induced striatal toxicity: a rat model of Huntington's disease.

Domenici MR, Chiodi V, Averna M, Armida M, Pèzzola A, Pepponi R, Ferrante A, Bader M, Fuxe K, Popoli P.

Purinergic Signal. 2018 May 16. doi: 10.1007/s11302-018-9609-4. [Epub ahead of print]

PMID:
29770921
2.

Stimulation of adenosine A2A receptors reduces intracellular cholesterol accumulation and rescues mitochondrial abnormalities in human neural cell models of Niemann-Pick C1.

Ferrante A, De Nuccio C, Pepponi R, Visentin S, Martire A, Bernardo A, Minghetti L, Popoli P.

Neuropharmacology. 2016 Apr;103:155-62. doi: 10.1016/j.neuropharm.2015.11.022. Epub 2015 Nov 26.

PMID:
26631535
3.

Expression, pharmacology and functional activity of adenosine A1 receptors in genetic models of Huntington's disease.

Ferrante A, Martire A, Pepponi R, Varani K, Vincenzi F, Ferraro L, Beggiato S, Tebano MT, Popoli P.

Neurobiol Dis. 2014 Nov;71:193-204. doi: 10.1016/j.nbd.2014.08.013. Epub 2014 Aug 15.

PMID:
25132555
4.

The stimulation of adenosine A2A receptors ameliorates the pathological phenotype of fibroblasts from Niemann-Pick type C patients.

Visentin S, De Nuccio C, Bernardo A, Pepponi R, Ferrante A, Minghetti L, Popoli P.

J Neurosci. 2013 Sep 25;33(39):15388-93. doi: 10.1523/JNEUROSCI.0558-13.2013.

5.

Interferon-Beta combined with interleukin-2 restores human natural cytotoxicity impaired in vitro by ionizing radiations.

Franzese O, Tricarico M, Starace G, Pepponi R, Bonmassar L, Cottarelli A, Fuggetta MP.

J Interferon Cytokine Res. 2013 Jun;33(6):308-18. doi: 10.1089/jir.2012.0025. Epub 2013 Feb 19.

PMID:
23421371
6.

BDNF prevents NMDA-induced toxicity in models of Huntington's disease: the effects are genotype specific and adenosine A2A receptor is involved.

Martire A, Pepponi R, Domenici MR, Ferrante A, Chiodi V, Popoli P.

J Neurochem. 2013 Apr;125(2):225-35. doi: 10.1111/jnc.12177. Epub 2013 Feb 27.

7.

Potential therapeutic relevance of adenosine A2B and A2A receptors in the central nervous system.

Popoli P, Pepponi R.

CNS Neurol Disord Drug Targets. 2012 Sep;11(6):664-74. Review.

PMID:
22963436
8.

Adenosine A2A receptors enable the synaptic effects of cannabinoid CB1 receptors in the rodent striatum.

Tebano MT, Martire A, Chiodi V, Pepponi R, Ferrante A, Domenici MR, Frank C, Chen JF, Ledent C, Popoli P.

J Neurochem. 2009 Sep;110(6):1921-30. doi: 10.1111/j.1471-4159.2009.06282.x. Epub 2009 Jul 17.

9.

Region-specific neuroprotective effect of ZM 241385 towards glutamate uptake inhibition in cultured neurons.

Pepponi R, Ferrante A, Ferretti R, Martire A, Popoli P.

Eur J Pharmacol. 2009 Sep 1;617(1-3):28-32. doi: 10.1016/j.ejphar.2009.07.016. Epub 2009 Jul 18.

PMID:
19619523
10.

A role for oxidized DNA precursors in Huntington's disease-like striatal neurodegeneration.

De Luca G, Russo MT, Degan P, Tiveron C, Zijno A, Meccia E, Ventura I, Mattei E, Nakabeppu Y, Crescenzi M, Pepponi R, Pèzzola A, Popoli P, Bignami M.

PLoS Genet. 2008 Nov;4(11):e1000266. doi: 10.1371/journal.pgen.1000266. Epub 2008 Nov 21.

11.

Is the functional interaction between adenosine A(2A) receptors and metabotropic glutamate 5 receptors a general mechanism in the brain? Differences and similarities between the striatum and the hippocampus.

Tebano MT, Martire A, Pepponi R, Domenici MR, Popoli P.

Purinergic Signal. 2006 Nov;2(4):619-25. doi: 10.1007/s11302-006-9026-y. Epub 2006 Sep 28.

12.

Adenosine A(2A) receptors modulate BDNF both in normal conditions and in experimental models of Huntington's disease.

Potenza RL, Tebano MT, Martire A, Domenici MR, Pepponi R, Armida M, Pèzzola A, Minghetti L, Popoli P.

Purinergic Signal. 2007 Sep;3(4):333-8. doi: 10.1007/s11302-007-9066-y. Epub 2007 Sep 15.

13.

Adenosine A(2A) receptors are required for normal BDNF levels and BDNF-induced potentiation of synaptic transmission in the mouse hippocampus.

Tebano MT, Martire A, Potenza RL, Grò C, Pepponi R, Armida M, Domenici MR, Schwarzschild MA, Chen JF, Popoli P.

J Neurochem. 2008 Jan;104(1):279-86. Epub 2007 Nov 14.

14.

Neuroprotective effects of thymosin beta4 in experimental models of excitotoxicity.

Popoli P, Pepponi R, Martire A, Armida M, Pèzzola A, Galluzzo M, Domenici MR, Potenza RL, Tebano MT, Mollinari C, Merlo D, Garaci E.

Ann N Y Acad Sci. 2007 Sep;1112:219-24.

PMID:
17947590
15.

Combined effect of temozolomide and hyperthermia on human melanoma cell growth and O6-methylguanine-DNA methyltransferase activity.

Pagani E, Falcinelli S, Pepponi R, Turriziani M, Caporaso P, Caporali S, Bonmassar E, D'Atri S.

Int J Oncol. 2007 Feb;30(2):443-51.

PMID:
17203227
16.

A single cycle of treatment with temozolomide, alone or combined with O(6)-benzylguanine, induces strong chemoresistance in melanoma cell clones in vitro: role of O(6)-methylguanine-DNA methyltransferase and the mismatch repair system.

Alvino E, Castiglia D, Caporali S, Pepponi R, Caporaso P, Lacal PM, Marra G, Fischer F, Zambruno G, Bonmassar E, Jiricny J, D'Atri S.

Int J Oncol. 2006 Oct;29(4):785-97.

PMID:
16964376
17.

Adenosine A2A receptors and metabotropic glutamate 5 receptors are co-localized and functionally interact in the hippocampus: a possible key mechanism in the modulation of N-methyl-D-aspartate effects.

Tebano MT, Martire A, Rebola N, Pepponi R, Domenici MR, Grò MC, Schwarzschild MA, Chen JF, Cunha RA, Popoli P.

J Neurochem. 2005 Nov;95(4):1188-200.

18.

Permissive role of adenosine A2A receptors on metabotropic glutamate receptor 5 (mGluR5)-mediated effects in the striatum.

Domenici MR, Pepponi R, Martire A, Tebano MT, Potenza RL, Popoli P.

J Neurochem. 2004 Sep;90(5):1276-9.

19.

Adenosine A2A receptor blockade differentially influences excitotoxic mechanisms at pre- and postsynaptic sites in the rat striatum.

Tebano MT, Pintor A, Frank C, Domenici MR, Martire A, Pepponi R, Potenza RL, Grieco R, Popoli P.

J Neurosci Res. 2004 Jul 1;77(1):100-7.

PMID:
15197743
20.

Neuroprotective effects of the mGlu5R antagonist MPEP towards quinolinic acid-induced striatal toxicity: involvement of pre- and post-synaptic mechanisms and lack of direct NMDA blocking activity.

Popoli P, Pintor A, Tebano MT, Frank C, Pepponi R, Nazzicone V, Grieco R, Pèzzola A, Reggio R, Minghetti L, De Berardinis MA, Martire A, Potenza RL, Domenici MR, Massotti M.

J Neurochem. 2004 Jun;89(6):1479-89.

21.

Cholesterol perturbing agents inhibit NMDA-dependent calcium influx in rat hippocampal primary culture.

Frank C, Giammarioli AM, Pepponi R, Fiorentini C, Rufini S.

FEBS Lett. 2004 May 21;566(1-3):25-9.

22.

Role of mismatch repair in the induction of chromosomal aberrations and sister chromatid exchanges in cells treated with different chemotherapeutic agents.

Vernole P, Pepponi R, D'Atri S.

Cancer Chemother Pharmacol. 2003 Sep;52(3):185-92. Epub 2003 Jun 19.

PMID:
12827294
23.

DNA repair enzymes and cytotoxic effects of temozolomide: comparative studies between tumor cells and normal cells of the immune system.

Pagani E, Pepponi R, Fuggetta MP, Prete SP, Turriziani M, Bonmassar L, Lacal PM, Falcinelli S, Passarelli F, Guadagni F, Alvino E, D'Atri S.

J Chemother. 2003 Apr;15(2):173-83.

PMID:
12797396
24.

The effect of O6-alkylguanine-DNA alkyltransferase and mismatch repair activities on the sensitivity of human melanoma cells to temozolomide, 1,3-bis(2-chloroethyl)1-nitrosourea, and cisplatin.

Pepponi R, Marra G, Fuggetta MP, Falcinelli S, Pagani E, Bonmassar E, Jiricny J, D'Atri S.

J Pharmacol Exp Ther. 2003 Feb;304(2):661-8.

25.

High-frequency microsatellite instability is associated with defective DNA mismatch repair in human melanoma.

Alvino E, Marra G, Pagani E, Falcinelli S, Pepponi R, Perrera C, Haider R, Castiglia D, Ferranti G, Bonmassar E, Jiricny J, Zambruno G, D'Atri S.

J Invest Dermatol. 2002 Jan;118(1):79-86.

26.

hMSH3 overexpression and cellular response to cytotoxic anticancer agents.

Pepponi R, Graziani G, Falcinelli S, Vernole P, Levati L, Lacal PM, Pagani E, Bonmassar E, Jiricny J, D'Atri S.

Carcinogenesis. 2001 Aug;22(8):1131-7.

PMID:
11470740
27.

In vitro effect of hyperthermia on natural cell-mediated cytotoxicity.

Fuggetta MP, Alvino E, Tricarico M, D'Atri S, Pepponi R, Prete SP, Bonmassar E.

Anticancer Res. 2000 May-Jun;20(3A):1667-72.

PMID:
10928089
28.

O(6)-benzylguanine enhances the in vitro immunotoxic activity of temozolomide on natural or antigen-dependent immunity.

Alvino E, Pepponi R, Pagani E, Lacal PM, Nunziata C, Bonmassar E, D'Atri S.

J Pharmacol Exp Ther. 1999 Dec;291(3):1292-300.

29.

Adjuvant treatment of breast cancer: a pilot immunochemotherapy study with CMF, interleukin-2 and interferon alpha.

Tonini G, Nunziata C, Prete SP, Pepponi R, Turriziani M, Masci G, Graziani G, Bonmassar E, De Vecchis L.

Cancer Immunol Immunother. 1998 Nov;47(3):157-66.

PMID:
9829841
30.

Effect of prostaglandin A1 on proliferation and telomerase activity of human melanoma cells in vitro.

Franzese O, Comandini A, Cannavò E, Pepponi R, Falcinelli S, Graziani G, Bonmassar E.

Melanoma Res. 1998 Aug;8(4):323-8.

PMID:
9764807
31.

Interferons antagonize gamma-ray-induced depression of natural immunity.

Fuggetta MP, Tricarico M, Starace G, Pepponi R, Bonmassar E.

Int J Radiat Oncol Biol Phys. 1998 Mar 1;40(4):953-60.

PMID:
9531381
32.

Cytokine-induced expression of CD1b molecules by peripheral blood monocytes: influence of 3'-azido-3'-deoxythymidine.

Giuliani A, Tentori L, Pepponi R, Porcelli SA, Aquino A, Orlando L, Sugita M, Brenner MB, Bonmassar E, Graziani G.

Pharmacol Res. 1997 Feb;35(2):135-40.

PMID:
9175583
33.

Effects of diheptyldiselenide (DDS) on human tumor cell lines and on peripheral blood mononuclear cells.

Tentori L, Prete SP, Pepponi R.

J Chemother. 1993 Oct;5(5):325-33.

PMID:
8106907
34.

In vitro tumour cell growth inhibition: a comparative study between allosensitized cytotoxic T lymphocytes and lymphokine activated killer cells.

Fuggetta MP, Alvino E, Pepponi R, De Filippi R, Marini S, Bonmassar E.

Cell Prolif. 1993 Jul;26(4):305-16.

PMID:
8343559
35.

In vitro combined effects of human interferons and interleukin-2 on natural cell-mediated cytotoxicity.

Fuggetta MP, Aquino A, Pepponi R, D'Atri S, Lanzilli G, Bonmassar E, Graziani G.

Int J Immunopharmacol. 1993 Jan;15(1):1-10.

PMID:
7679378
36.

Increase of NK activity of irradiated mononuclear cells induced by interferon in vitro.

Fuggetta MP, Pepponi R, D'Atri S, Mirabelli F, Tricarico M.

J Chemother. 1989 Jul;1(4 Suppl):1164-7. No abstract available.

PMID:
16312817

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