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Items: 1 to 50 of 366

1.

Suppression of hepatocellular carcinoma by mycophenolic acid in experimental models and in patients.

Chen K, Sheng J, Ma B, Cao W, Hernanda PY, Liu J, Boor PPC, Tjon ASW, Felczak K, Sprengers D, Pankiewicz KW, Metselaar HJ, Ma Z, Kwekkeboom J, Peppelenbosch MP, Pan Q.

Transplantation. 2019 Feb 4. doi: 10.1097/TP.0000000000002647. [Epub ahead of print]

PMID:
30747839
2.

Direct-acting antiviral agents for liver transplant recipients with recurrent genotype 1 hepatitis C virus infection: Systematic review and meta-analysis.

Liu J, Ma B, Cao W, Li M, Bramer WM, Peppelenbosch MP, Pan Q.

Transpl Infect Dis. 2019 Jan 7:e13047. doi: 10.1111/tid.13047. [Epub ahead of print] Review.

PMID:
30615227
3.

Sofosbuvir directly promotes the clonogenic capability of human hepatocellular carcinoma cells.

Liu J, Cao W, Ma B, Li M, Peppelenbosch MP, Pan Q.

Clin Res Hepatol Gastroenterol. 2018 Dec 26. pii: S2210-7401(18)30278-X. doi: 10.1016/j.clinre.2018.11.016. [Epub ahead of print] No abstract available.

PMID:
30594596
4.

Kinase activity is impaired in neutrophils of sepsis patients.

Hoogendijk AJ, van Vught LA, Wiewel MA, Fuhler GM, Belkasim-Bohoudi H, Horn J, Schultz MJ, Scicluna BP, Peppelenbosch MP, van 't Veer C, de Vos AF, van der Poll T.

Haematologica. 2018 Dec 4. pii: haematol.2018.201913. doi: 10.3324/haematol.2018.201913. [Epub ahead of print]

5.

Dichotomal functions of phosphorylated and unphosphorylated STAT1 in hepatocellular carcinoma.

Ma B, Chen K, Liu P, Li M, Liu J, Sideras K, Sprengers D, Biermann K, Wang W, IJzermans JNM, Cao W, Kwekkeboom J, Peppelenbosch MP, Pan Q.

J Mol Med (Berl). 2019 Jan;97(1):77-88. doi: 10.1007/s00109-018-1717-7. Epub 2018 Nov 19.

6.

Signaling Size: Ankyrin and SOCS Box-Containing ASB E3 Ligases in Action.

Liu P, Verhaar AP, Peppelenbosch MP.

Trends Biochem Sci. 2019 Jan;44(1):64-74. doi: 10.1016/j.tibs.2018.10.003. Epub 2018 Nov 13. Review.

PMID:
30446376
7.

Action and clinical significance of CCAAT/enhancer-binding protein delta in hepatocellular carcinoma.

Liu P, Cao W, Ma B, Li M, Chen K, Sideras K, Duitman JW, Sprengers D, Tran TCK, Ijzermans JNM, Biermann K, Verheij J, Spek CA, Kwekkeboom J, Pan Q, Peppelenbosch MP.

Carcinogenesis. 2018 Oct 16. doi: 10.1093/carcin/bgy130. [Epub ahead of print]

PMID:
30325409
8.

Modeling liver cancer and therapy responsiveness using organoids derived from primary mouse liver tumors.

Cao W, Liu J, Wang L, Li M, Verstegen MMA, Yin Y, Ma B, Chen K, Bolkestein M, Sprengers D, van der Laan LJW, Doukas M, Kwekkeboom J, Smits R, Peppelenbosch MP, Pan Q.

Carcinogenesis. 2018 Oct 5. doi: 10.1093/carcin/bgy129. [Epub ahead of print]

PMID:
30289434
9.

Recombinant identification, molecular classification and proposed reference genomes for hepatitis delta virus.

Miao Z, Zhang S, Ma Z, Hakim MS, Wang W, Peppelenbosch MP, Pan Q.

J Viral Hepat. 2019 Jan;26(1):183-190. doi: 10.1111/jvh.13010. Epub 2018 Oct 19.

PMID:
30260538
10.

Oncogenic STRAP Supports Hepatocellular Carcinoma Growth by Enhancing Wnt/β-Catenin Signaling.

Wang W, Li S, Liu P, Sideras K, van de Werken HJG, van der Heide M, Cao W, Lavrijsen M, Peppelenbosch MP, Bruno M, Pan Q, Smits R.

Mol Cancer Res. 2019 Feb;17(2):521-531. doi: 10.1158/1541-7786.MCR-18-0054. Epub 2018 Sep 26.

PMID:
30257989
11.

Laminar shear stress-provoked cytoskeletal changes are mediated by epigenetic reprogramming of TIMP1 in human primary smooth muscle cells.

da Silva RA, Fernandes CJDC, Feltran GDS, Gomes AM, de Camargo Andrade AF, Andia DC, Peppelenbosch MP, Zambuzzi WF.

J Cell Physiol. 2019 May;234(5):6382-6396. doi: 10.1002/jcp.27374. Epub 2018 Sep 21.

PMID:
30238981
12.

The Burden of Human Papillomavirus and Chlamydia trachomatis Coinfection in Women: A Large Cohort Study in Inner Mongolia, China.

Ji Y, Ma XX, Li Z, Peppelenbosch MP, Ma Z, Pan Q.

J Infect Dis. 2019 Jan 7;219(2):206-214. doi: 10.1093/infdis/jiy497.

PMID:
30192954
13.

Hepatitis E virus infection in acute non-traumatic neuropathy: A large prospective case-control study in China.

Wang Y, Wang S, Wu J, Jiang Y, Zhang H, Li S, Liu H, Yang C, Tang H, Guo N, Peppelenbosch MP, Wei L, Pan Q, Zhao J.

EBioMedicine. 2018 Oct;36:122-130. doi: 10.1016/j.ebiom.2018.08.053. Epub 2018 Sep 3.

14.

Conservation and variation of the hepatitis E virus ORF2 capsid protein.

Zhang S, Qu C, Wang Y, Wang W, Ma Z, Peppelenbosch MP, Pan Q.

Gene. 2018 Oct 30;675:157-164. doi: 10.1016/j.gene.2018.06.108. Epub 2018 Jul 2.

PMID:
30180962
15.

Nitazoxanide Inhibits Human Norovirus Replication and Synergizes with Ribavirin by Activation of Cellular Antiviral Response.

Dang W, Xu L, Ma B, Chen S, Yin Y, Chang KO, Peppelenbosch MP, Pan Q.

Antimicrob Agents Chemother. 2018 Oct 24;62(11). pii: e00707-18. doi: 10.1128/AAC.00707-18. Print 2018 Nov.

PMID:
30104275
16.

Incompatible Translation Drives a Convergent Evolution and Viral Attenuation During the Development of Live Attenuated Vaccine.

Ou X, Wang M, Mao S, Cao J, Cheng A, Zhu D, Chen S, Jia R, Liu M, Yang Q, Wu Y, Zhao X, Zhang S, Liu Y, Yu Y, Zhang L, Chen X, Peppelenbosch MP, Pan Q.

Front Cell Infect Microbiol. 2018 Jul 18;8:249. doi: 10.3389/fcimb.2018.00249. eCollection 2018.

17.

Mitochondrial electron transport chain complex III sustains hepatitis E virus replication and represents an antiviral target.

Qu C, Zhang S, Wang W, Li M, Wang Y, van der Heijde-Mulder M, Shokrollahi E, Hakim MS, Raat NJH, Peppelenbosch MP, Pan Q.

FASEB J. 2019 Jan;33(1):1008-1019. doi: 10.1096/fj.201800620R. Epub 2018 Aug 2.

PMID:
30070932
18.

Human mesenchymal stromal cells in adhesion to cell-derived extracellular matrix and titanium: Comparative kinome profile analysis.

Baroncelli M, Fuhler GM, van de Peppel J, Zambuzzi WF, van Leeuwen JP, van der Eerden BCJ, Peppelenbosch MP.

J Cell Physiol. 2019 Mar;234(3):2984-2996. doi: 10.1002/jcp.27116. Epub 2018 Jul 30.

PMID:
30058720
19.

6-Thioguanine inhibits rotavirus replication through suppression of Rac1 GDP/GTP cycling.

Yin Y, Chen S, Hakim MS, Wang W, Xu L, Dang W, Qu C, Verhaar AP, Su J, Fuhler GM, Peppelenbosch MP, Pan Q.

Antiviral Res. 2018 Aug;156:92-101. doi: 10.1016/j.antiviral.2018.06.011. Epub 2018 Jun 18.

20.

Surveillance of premalignant gastric lesions: a multicentre prospective cohort study from low incidence regions.

den Hollander WJ, Holster IL, den Hoed CM, Capelle LG, Tang TJ, Anten MP, Prytz-Berset I, Witteman EM, Ter Borg F, Hartog GD, Bruno MJ, Peppelenbosch MP, Lesterhuis W, Doukas M, Kuipers EJ, Spaander MCW.

Gut. 2018 Jun 6. pii: gutjnl-2017-314498. doi: 10.1136/gutjnl-2017-314498. [Epub ahead of print]

PMID:
29875257
21.

TNF-α exerts potent anti-rotavirus effects via the activation of classical NF-κB pathway.

Hakim MS, Ding S, Chen S, Yin Y, Su J, van der Woude CJ, Fuhler GM, Peppelenbosch MP, Pan Q, Wang W.

Virus Res. 2018 Jul 15;253:28-37. doi: 10.1016/j.virusres.2018.05.022. Epub 2018 May 31.

22.

Basal interferon signaling and therapeutic use of interferons in controlling rotavirus infection in human intestinal cells and organoids.

Hakim MS, Chen S, Ding S, Yin Y, Ikram A, Ma XX, Wang W, Peppelenbosch MP, Pan Q.

Sci Rep. 2018 May 29;8(1):8341. doi: 10.1038/s41598-018-26784-9.

23.

IRF-1, RIG-I and MDA5 display potent antiviral activities against norovirus coordinately induced by different types of interferons.

Dang W, Xu L, Yin Y, Chen S, Wang W, Hakim MS, Chang KO, Peppelenbosch MP, Pan Q.

Antiviral Res. 2018 Jul;155:48-59. doi: 10.1016/j.antiviral.2018.05.004. Epub 2018 May 10.

24.

Gastric cancer and Hedgehog signaling pathway: emerging new paradigms.

Akyala AI, Peppelenbosch MP.

Genes Cancer. 2018 Jan;9(1-2):1-10. doi: 10.18632/genesandcancer.168. Review.

25.

The gastrointestinal microbiota and its role in oncogenesis.

Lam SY, Yu J, Wong SH, Peppelenbosch MP, Fuhler GM.

Best Pract Res Clin Gastroenterol. 2017 Dec;31(6):607-618. doi: 10.1016/j.bpg.2017.09.010. Epub 2017 Sep 5. Review.

PMID:
29566903
26.

Preface to "Gut microbiome in health and disease".

Peppelenbosch MP.

Best Pract Res Clin Gastroenterol. 2017 Dec;31(6):605-606. doi: 10.1016/j.bpg.2017.10.007. Epub 2017 Nov 4. No abstract available.

PMID:
29566902
27.

Low dose Naltrexone for induction of remission in inflammatory bowel disease patients.

Lie MRKL, van der Giessen J, Fuhler GM, de Lima A, Peppelenbosch MP, van der Ent C, van der Woude CJ.

J Transl Med. 2018 Mar 9;16(1):55. doi: 10.1186/s12967-018-1427-5.

28.

Correlating Fecal Calprotectin With Hemoglobin Levels Within 1 Sample.

Fuhler GM, van der Giessen J, van der Woude CJ, Peppelenbosch MP.

Inflamm Bowel Dis. 2018 Feb 15;24(3):663. doi: 10.1093/ibd/izx028. No abstract available.

PMID:
29462378
29.

Helicobacter pylori Pathogenicity Factors Related to Gastric Cancer.

Dadashzadeh K, Peppelenbosch MP, Adamu AI.

Can J Gastroenterol Hepatol. 2017;2017:7942489. doi: 10.1155/2017/7942489. Epub 2017 Dec 17.

30.

Phosphoproteome profiling reveals critical role of JAK-STAT signaling in maintaining chemoresistance in breast cancer.

Nascimento AS, Peres LL, Fari AVS, Milani R, Silva RA, da Costa Fernandes CJ, Peppelenbosch MP, Ferreira-Halder CV, Zambuzzi WF.

Oncotarget. 2017 Oct 10;8(70):114756-114768. doi: 10.18632/oncotarget.21801. eCollection 2017 Dec 29.

31.

Immunity against hepatitis E virus infection: Implications for therapy and vaccine development.

Hakim MS, Ikram A, Zhou J, Wang W, Peppelenbosch MP, Pan Q.

Rev Med Virol. 2018 Mar;28(2). doi: 10.1002/rmv.1964. Epub 2017 Dec 22. Review.

PMID:
29272060
32.

Genetic polymorphism in ATG16L1 gene is associated with adalimumab use in inflammatory bowel disease.

Nuij VJAA, Peppelenbosch MP, van der Woude CJ, Fuhler GM.

J Transl Med. 2017 Dec 11;15(1):248. doi: 10.1186/s12967-017-1355-9.

33.

The RNA genome of hepatitis E virus robustly triggers an antiviral interferon response.

Wang W, Wang Y, Qu C, Wang S, Zhou J, Cao W, Xu L, Ma B, Hakim MS, Yin Y, Li T, Peppelenbosch MP, Zhao J, Pan Q.

Hepatology. 2018 Jun;67(6):2096-2112. doi: 10.1002/hep.29702. Epub 2018 Apr 19.

PMID:
29194722
34.

Palliative chemotherapy and targeted therapies for esophageal and gastroesophageal junction cancer.

Janmaat VT, Steyerberg EW, van der Gaast A, Mathijssen RH, Bruno MJ, Peppelenbosch MP, Kuipers EJ, Spaander MC.

Cochrane Database Syst Rev. 2017 Nov 28;11:CD004063. doi: 10.1002/14651858.CD004063.pub4. Review.

PMID:
29182797
35.

Genetic host factors in Helicobacter pylori-induced carcinogenesis: Emerging new paradigms.

Mommersteeg MC, Yu J, Peppelenbosch MP, Fuhler GM.

Biochim Biophys Acta Rev Cancer. 2018 Jan;1869(1):42-52. doi: 10.1016/j.bbcan.2017.11.003. Epub 2017 Nov 24. Review.

PMID:
29154808
36.

Pancreatic cyst fluid harbors a unique microbiome.

Li S, Fuhler GM, Bn N, Jose T, Bruno MJ, Peppelenbosch MP, Konstantinov SR.

Microbiome. 2017 Nov 9;5(1):147. doi: 10.1186/s40168-017-0363-6.

37.

Erratum to: Action and function of Wnt/β-catenin signaling in the progression from chronic hepatitis C to hepatocellular carcinoma.

Wang W, Pan Q, Fuhler GM, Smits R, Peppelenbosch MP.

J Gastroenterol. 2018 Apr;53(4):576-577. doi: 10.1007/s00535-017-1392-4.

PMID:
29022044
38.

Opposing Effects of Nitazoxanide on Murine and Human Norovirus.

Dang W, Yin Y, Peppelenbosch MP, Pan Q.

J Infect Dis. 2017 Sep 15;216(6):780-782. doi: 10.1093/infdis/jix377. No abstract available.

PMID:
28934433
39.

Serum levels of caspase-cleaved cytokeratin 18 (CK18-Asp396) predict severity of liver disease in chronic hepatitis B.

Li J, Verhaar AP, Pan Q, de Knegt RJ, Peppelenbosch MP.

Clin Exp Gastroenterol. 2017 Aug 11;10:203-209. doi: 10.2147/CEG.S135526. eCollection 2017.

40.

Inhibition of Calcineurin or IMP Dehydrogenase Exerts Moderate to Potent Antiviral Activity against Norovirus Replication.

Dang W, Yin Y, Wang Y, Wang W, Su J, Sprengers D, van der Laan LJW, Felczak K, Pankiewicz KW, Chang KO, Koopmans MPG, Metselaar HJ, Peppelenbosch MP, Pan Q.

Antimicrob Agents Chemother. 2017 Oct 24;61(11). pii: e01095-17. doi: 10.1128/AAC.01095-17. Print 2017 Nov.

41.

Analysis of SHIP1 expression and activity in Crohn's disease patients.

Somasundaram R, Fernandes S, Deuring JJ, de Haar C, Kuipers EJ, Vogelaar L, Middleton FA, van der Woude CJ, Peppelenbosch MP, Kerr WG, Fuhler GM.

PLoS One. 2017 Aug 2;12(8):e0182308. doi: 10.1371/journal.pone.0182308. eCollection 2017.

42.

Genetically Engineered Bacteria for Treating Human Disease.

Ma B, Pan Q, Peppelenbosch MP.

Trends Pharmacol Sci. 2017 Sep;38(9):763-764. doi: 10.1016/j.tips.2017.07.001. Epub 2017 Jul 28.

PMID:
28760488
43.

Cytoplasmic rods and rings in mycophenolic acid treatment.

Chen K, Ma B, Peppelenbosch MP, Pan Q.

Liver Int. 2017 Nov;37(11):1742-1743. doi: 10.1111/liv.13530. Epub 2017 Aug 10. No abstract available.

PMID:
28746782
44.

Genotype-specific acquisition, evolution and adaptation of characteristic mutations in hepatitis E virus.

Ikram A, Hakim MS, Zhou JH, Wang W, Peppelenbosch MP, Pan Q.

Virulence. 2018 Jan 1;9(1):121-132. doi: 10.1080/21505594.2017.1358349. Epub 2017 Aug 18.

45.

Dynamics of Proliferative and Quiescent Stem Cells in Liver Homeostasis and Injury.

Cao W, Chen K, Bolkestein M, Yin Y, Verstegen MMA, Bijvelds MJC, Wang W, Tuysuz N, Ten Berge D, Sprengers D, Metselaar HJ, van der Laan LJW, Kwekkeboom J, Smits R, Peppelenbosch MP, Pan Q.

Gastroenterology. 2017 Oct;153(4):1133-1147. doi: 10.1053/j.gastro.2017.07.006. Epub 2017 Jul 14.

PMID:
28716722
46.

Prevalence of human papillomavirus infection in women in the Autonomous Region of Inner Mongolia: A population-based study of a Chinese ethnic minority.

Wang X, Ji Y, Li J, Dong H, Zhu B, Zhou Y, Wang J, Zhou X, Wang Y, Peppelenbosch MP, Pan Q, Ji X, Liu D.

J Med Virol. 2018 Jan;90(1):148-156. doi: 10.1002/jmv.24888. Epub 2017 Oct 6.

PMID:
28661048
47.

Phosphoproteome analysis reveals a critical role for hedgehog signalling in osteoblast morphological transitions.

Marumoto A, Milani R, da Silva RA, da Costa Fernandes CJ, Granjeiro JM, Ferreira CV, Peppelenbosch MP, Zambuzzi WF.

Bone. 2017 Oct;103:55-63. doi: 10.1016/j.bone.2017.06.012. Epub 2017 Jun 17.

PMID:
28633965
48.

Nucleoside analogue 2'-C-methylcytidine inhibits hepatitis E virus replication but antagonizes ribavirin.

Qu C, Xu L, Yin Y, Peppelenbosch MP, Pan Q, Wang W.

Arch Virol. 2017 Oct;162(10):2989-2996. doi: 10.1007/s00705-017-3444-8. Epub 2017 Jun 16.

49.

Prevalence and Phenotype of Concurrent Psoriasis and Inflammatory Bowel Disease.

Eppinga H, Poortinga S, Thio HB, Nijsten TEC, Nuij VJAA, van der Woude CJ, Vodegel RM, Fuhler GM, Peppelenbosch MP.

Inflamm Bowel Dis. 2017 Oct;23(10):1783-1789. doi: 10.1097/MIB.0000000000001169.

PMID:
28617755
50.

Should Nivolumab-Induced Colitis Be Treated by Infliximab?

Li M, Pan Q, Peppelenbosch MP.

Clin Gastroenterol Hepatol. 2017 Oct;15(10):1637. doi: 10.1016/j.cgh.2017.05.012. Epub 2017 May 18. No abstract available.

PMID:
28529167

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