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Items: 1 to 50 of 135

1.

Determinants of diagnostic delay in Chronic Thromboembolic Pulmonary Hypertension: results from the European CTEPH registry.

Klok FA, Barco S, Konstantinides SV, Dartevelle P, Fadel E, Jenkins D, Kim NH, Madani M, Matsubara H, Mayer E, Pepke-Zaba J, Delcroix M, Lang IM.

Eur Respir J. 2018 Nov 8. pii: 1801687. doi: 10.1183/13993003.01687-2018. [Epub ahead of print] No abstract available.

PMID:
30409820
2.

Limitations of resting haemodynamics in chronic thromboembolic disease without pulmonary hypertension.

Swietlik EM, Ruggiero A, Fletcher AJ, Taboada D, Knightbridge E, Harlow L, Harvey I, Screaton N, Cannon JE, Sheares KKK, Ng C, Jenkins DP, Pepke-Zaba J, Toshner MR.

Eur Respir J. 2018 Nov 8. pii: 1801787. doi: 10.1183/13993003.01787-2018. [Epub ahead of print] No abstract available.

PMID:
30409818
3.

Loss-of-Function ABCC8 Mutations in Pulmonary Arterial Hypertension.

Bohnen MS, Ma L, Zhu N, Qi H, McClenaghan C, Gonzaga-Jauregui C, Dewey FE, Overton JD, Reid JG, Shuldiner AR, Baras A, Sampson KJ, Bleda M, Hadinnapola C, Haimel M, Bogaard HJ, Church C, Coghlan G, Corris PA, Eyries M, Gibbs JSR, Girerd B, Houweling AC, Humbert M, Guignabert C, Kiely DG, Lawrie A, MacKenzie Ross RV, Martin JM, Montani D, Peacock AJ, Pepke-Zaba J, Soubrier F, Suntharalingam J, Toshner M, Treacy CM, Trembath RC, Vonk Noordegraaf A, Wharton J, Wilkins MR, Wort SJ, Yates K, Gräf S, Morrell NW, Krishnan U, Rosenzweig EB, Shen Y, Nichols CG, Kass RS, Chung WK.

Circ Genom Precis Med. 2018 Oct;11(10):e002087. doi: 10.1161/CIRCGEN.118.002087.

PMID:
30354297
4.

Risk assessment in medically treated chronic thromboembolic pulmonary hypertension patients.

Delcroix M, Staehler G, Gall H, Grünig E, Held M, Halank M, Klose H, Vonk-Noordegraaf A, Rosenkranz S, Pepke-Zaba J, Opitz CF, Gibbs JSR, Lange TJ, Tsangaris I, Huscher D, Pittrow D, Olsson KM, Hoeper MM.

Eur Respir J. 2018 Nov 8;52(5). pii: 1800248. doi: 10.1183/13993003.00248-2018. Print 2018 Nov.

PMID:
30337446
5.

The impact of patient choice on survival in chronic thromboembolic pulmonary hypertension.

Quadery SR, Swift AJ, Billings CG, Thompson AAR, Elliot CA, Hurdman J, Charalampopoulos A, Sabroe I, Armstrong IJ, Hamilton N, Sephton P, Garrad S, Pepke-Zaba J, Jenkins DP, Screaton N, Rothman AM, Lawrie A, Cleveland T, Thomas S, Rajaram S, Hill C, Davies C, Johns CS, Wild JM, Condliffe R, Kiely DG.

Eur Respir J. 2018 Sep 16;52(3). pii: 1800589. doi: 10.1183/13993003.00589-2018. Print 2018 Sep.

PMID:
30002102
6.

Identification of rare sequence variation underlying heritable pulmonary arterial hypertension.

Gräf S, Haimel M, Bleda M, Hadinnapola C, Southgate L, Li W, Hodgson J, Liu B, Salmon RM, Southwood M, Machado RD, Martin JM, Treacy CM, Yates K, Daugherty LC, Shamardina O, Whitehorn D, Holden S, Aldred M, Bogaard HJ, Church C, Coghlan G, Condliffe R, Corris PA, Danesino C, Eyries M, Gall H, Ghio S, Ghofrani HA, Gibbs JSR, Girerd B, Houweling AC, Howard L, Humbert M, Kiely DG, Kovacs G, MacKenzie Ross RV, Moledina S, Montani D, Newnham M, Olschewski A, Olschewski H, Peacock AJ, Pepke-Zaba J, Prokopenko I, Rhodes CJ, Scelsi L, Seeger W, Soubrier F, Stein DF, Suntharalingam J, Swietlik EM, Toshner MR, van Heel DA, Vonk Noordegraaf A, Waisfisz Q, Wharton J, Wort SJ, Ouwehand WH, Soranzo N, Lawrie A, Upton PD, Wilkins MR, Trembath RC, Morrell NW.

Nat Commun. 2018 Apr 12;9(1):1416. doi: 10.1038/s41467-018-03672-4.

7.

The outcome of reoperative pulmonary endarterectomy surgery.

Ali JM, Dunning J, Ng C, Tsui S, Cannon JE, Sheares KK, Taboada D, Toshner M, Screaton N, Pepke-Zaba J, Jenkins DP.

Interact Cardiovasc Thorac Surg. 2018 Jun 1;26(6):932-937. doi: 10.1093/icvts/ivx424.

PMID:
29373658
8.

Riociguat in patients with chronic thromboembolic pulmonary hypertension: results from an early access study.

McLaughlin VV, Jansa P, Nielsen-Kudsk JE, Halank M, Simonneau G, Grünig E, Ulrich S, Rosenkranz S, Gómez Sánchez MA, Pulido T, Pepke-Zaba J, Barberá JA, Hoeper MM, Vachiéry JL, Lang I, Carvalho F, Meier C, Mueller K, Nikkho S, D'Armini AM.

BMC Pulm Med. 2017 Dec 28;17(1):216. doi: 10.1186/s12890-017-0563-7.

9.

Acute and chronic dissection of pulmonary artery: new challenges in pulmonary arterial hypertension?

Florczyk M, Wieteska M, Kurzyna M, Gościniak P, Pepke-Żaba J, Biederman A, Torbicki A.

Pulm Circ. 2018 Apr-Jun;8(2):2045893217749114. doi: 10.1177/2045893217749114. Epub 2017 Dec 18.

10.

The potential effects of pregnancy in a patient with idiopathic pulmonary arterial hypertension responding to calcium channel blockade.

Bostock S, Sheares K, Cannon J, Taboada D, Pepke-Zaba J, Toshner M.

Eur Respir J. 2017 Dec 14;50(6). pii: 1701141. doi: 10.1183/13993003.01141-2017. Print 2017 Dec. No abstract available.

PMID:
29242260
11.

Age should not be a barrier for pulmonary endarterectomy in carefully selected patients.

Newnham M, Hernández-Sánchez J, Dunning J, Ng C, Tsui S, Bunclark K, Sheares K, Taboada D, Toshner M, Pepke-Zaba J, Jenkins D, Cannon J.

Eur Respir J. 2017 Dec 7;50(6). pii: 1701804. doi: 10.1183/13993003.01804-2017. Print 2017 Dec. No abstract available.

PMID:
29217606
12.

Medication and patient factors associated with adherence to pulmonary hypertension targeted therapies.

Grady D, Weiss M, Hernandez-Sanchez J, Pepke-Zaba J.

Pulm Circ. 2018 Jan-Mar;8(1):2045893217743616. doi: 10.1177/2045893217743616. Epub 2017 Nov 3.

13.

Phenotypic Characterization of EIF2AK4 Mutation Carriers in a Large Cohort of Patients Diagnosed Clinically With Pulmonary Arterial Hypertension.

Hadinnapola C, Bleda M, Haimel M, Screaton N, Swift A, Dorfmüller P, Preston SD, Southwood M, Hernandez-Sanchez J, Martin J, Treacy C, Yates K, Bogaard H, Church C, Coghlan G, Condliffe R, Corris PA, Gibbs S, Girerd B, Holden S, Humbert M, Kiely DG, Lawrie A, Machado R, MacKenzie Ross R, Moledina S, Montani D, Newnham M, Peacock A, Pepke-Zaba J, Rayner-Matthews P, Shamardina O, Soubrier F, Southgate L, Suntharalingam J, Toshner M, Trembath R, Vonk Noordegraaf A, Wilkins MR, Wort SJ, Wharton J; NIHR BioResource–Rare Diseases Consortium; UK National Cohort Study of Idiopathic and Heritable PAH, Gräf S, Morrell NW.

Circulation. 2017 Nov 21;136(21):2022-2033. doi: 10.1161/CIRCULATIONAHA.117.028351. Epub 2017 Sep 28.

14.

The CRASH report: emergency management dilemmas facing acute physicians in patients with pulmonary arterial hypertension.

Price LC, Dimopoulos K, Marino P, Alonso-Gonzalez R, McCabe C, Kemnpy A, Swan L, Boutsikou M, Al Zahrani A, Coghlan GJ, Schreiber BE, Howard LS, Davies R, Toshner M, Pepke-Zaba J, Church AC, Peacock A, Corris PA, Lordan JL, Gaine S, Condliffe R, Kiely DG, Wort SJ.

Thorax. 2017 Nov;72(11):1035-1045. doi: 10.1136/thoraxjnl-2016-209725. Epub 2017 Sep 12. Review.

PMID:
28904006
15.

Ventriculo-arterial coupling detects occult RV dysfunction in chronic thromboembolic pulmonary vascular disease.

Axell RG, Messer SJ, White PA, McCabe C, Priest A, Statopoulou T, Drozdzynska M, Viscasillas J, Hinchy EC, Hampton-Till J, Alibhai HI, Morrell N, Pepke-Zaba J, Large SR, Hoole SP.

Physiol Rep. 2017 Apr;5(7). pii: e13227. doi: 10.14814/phy2.13227.

16.

Medical management of chronic thromboembolic pulmonary hypertension.

Pepke-Zaba J, Ghofrani HA, Hoeper MM.

Eur Respir Rev. 2017 Mar 29;26(143). pii: 160107. doi: 10.1183/16000617.0107-2016. Print 2017 Mar 31. Review.

17.

Survival in portopulmonary hypertension: Outcomes of the United Kingdom National Pulmonary Arterial Hypertension Registry.

Sithamparanathan S, Nair A, Thirugnanasothy L, Coghlan JG, Condliffe R, Dimopoulos K, Elliot CA, Fisher AJ, Gaine S, Gibbs JSR, Gatzoulis MA, E Handler C, Howard LS, Johnson M, Kiely DG, Lordan JL, Peacock AJ, Pepke-Zaba J, Schreiber BE, Sheares KKK, Wort SJ, Corris PA; National Pulmonary Hypertension Service Research Collaboration of the United Kingdom and Ireland.

J Heart Lung Transplant. 2017 Jul;36(7):770-779. doi: 10.1016/j.healun.2016.12.014. Epub 2016 Dec 31.

PMID:
28190786
18.

Plasma Metabolomics Implicates Modified Transfer RNAs and Altered Bioenergetics in the Outcomes of Pulmonary Arterial Hypertension.

Rhodes CJ, Ghataorhe P, Wharton J, Rue-Albrecht KC, Hadinnapola C, Watson G, Bleda M, Haimel M, Coghlan G, Corris PA, Howard LS, Kiely DG, Peacock AJ, Pepke-Zaba J, Toshner MR, Wort SJ, Gibbs JS, Lawrie A, Gräf S, Morrell NW, Wilkins MR.

Circulation. 2017 Jan 31;135(5):460-475. doi: 10.1161/CIRCULATIONAHA.116.024602. Epub 2016 Nov 21.

20.

Contemporary diagnosis and management of pulmonary hypertension.

Cannon JE, Pepke-Zaba J.

Heart. 2016 Oct 15;102(20):1680-91. doi: 10.1136/heartjnl-2015-307996. Review. No abstract available.

PMID:
27679806
21.

Medical Therapy in Chronic Thromboembolic Pulmonary Hypertension.

Pepke-Zaba J, Jais X, Channick R.

Ann Am Thorac Soc. 2016 Jul;13 Suppl 3:S248-54. doi: 10.1513/AnnalsATS.201512-802AS. Review.

PMID:
27571006
22.

Chronic Thromboembolic Pulmonary Hypertension. The Journey from a Curiosity to a Cure.

Auger WR, Mandel J, Pepke-Zaba J.

Ann Am Thorac Soc. 2016 Jul;13 Suppl 3:S197-200. doi: 10.1513/AnnalsATS.201509-618AS.

PMID:
27571000
23.

Neutrophil Extracellular Traps Promote Angiogenesis: Evidence From Vascular Pathology in Pulmonary Hypertension.

Aldabbous L, Abdul-Salam V, McKinnon T, Duluc L, Pepke-Zaba J, Southwood M, Ainscough AJ, Hadinnapola C, Wilkins MR, Toshner M, Wojciak-Stothard B.

Arterioscler Thromb Vasc Biol. 2016 Oct;36(10):2078-87. doi: 10.1161/ATVBAHA.116.307634. Epub 2016 Jul 28.

24.

Pre-Capillary, Combined, and Post-Capillary Pulmonary Hypertension: A Pathophysiological Continuum.

Opitz CF, Hoeper MM, Gibbs JS, Kaemmerer H, Pepke-Zaba J, Coghlan JG, Scelsi L, D'Alto M, Olsson KM, Ulrich S, Scholtz W, Schulz U, Grünig E, Vizza CD, Staehler G, Bruch L, Huscher D, Pittrow D, Rosenkranz S.

J Am Coll Cardiol. 2016 Jul 26;68(4):368-78. doi: 10.1016/j.jacc.2016.05.047.

25.

Exercise physiological responses to drug treatments in chronic thromboembolic pulmonary hypertension.

Charalampopoulos A, Gibbs JS, Davies RJ, Gin-Sing W, Murphy K, Sheares KK, Pepke-Zaba J, Jenkins DP, Howard LS.

J Appl Physiol (1985). 2016 Sep 1;121(3):623-8. doi: 10.1152/japplphysiol.00087.2016. Epub 2016 Jul 14.

26.

Quality of life in patients with chronic thromboembolic pulmonary hypertension.

Mathai SC, Ghofrani HA, Mayer E, Pepke-Zaba J, Nikkho S, Simonneau G.

Eur Respir J. 2016 Aug;48(2):526-37. doi: 10.1183/13993003.01626-2015. Epub 2016 Apr 13. Review.

27.

Dynamic Risk Stratification of Patient Long-Term Outcome After Pulmonary Endarterectomy: Results From the United Kingdom National Cohort.

Cannon JE, Su L, Kiely DG, Page K, Toshner M, Swietlik E, Treacy C, Ponnaberanam A, Condliffe R, Sheares K, Taboada D, Dunning J, Tsui S, Ng C, Gopalan D, Screaton N, Elliot C, Gibbs S, Howard L, Corris P, Lordan J, Johnson M, Peacock A, MacKenzie-Ross R, Schreiber B, Coghlan G, Dimopoulos K, Wort SJ, Gaine S, Moledina S, Jenkins DP, Pepke-Zaba J.

Circulation. 2016 May 3;133(18):1761-71. doi: 10.1161/CIRCULATIONAHA.115.019470. Epub 2016 Apr 6.

28.

Pulmonary endarterectomy is effective and safe in patients with haemoglobinopathies and abnormal red blood cells: the Papworth experience.

Mahesh B, Besser M, Ravaglioli A, Pepke-Zaba J, Martinez G, Klein A, Ng C, Tsui S, Dunning J, Jenkins DP.

Eur J Cardiothorac Surg. 2016 Sep;50(3):537-41. doi: 10.1093/ejcts/ezw062. Epub 2016 Mar 17.

PMID:
26987879
29.

Endothelin ETA receptors predominate in chronic thromboembolic pulmonary hypertension.

Southwood M, MacKenzie Ross RV, Kuc RE, Hagan G, Sheares KK, Jenkins DP, Goddard M, Davenport AP, Pepke-Zaba J.

Life Sci. 2016 Aug 15;159:104-110. doi: 10.1016/j.lfs.2016.02.036. Epub 2016 Feb 10.

30.

Long-Term Outcome of Patients With Chronic Thromboembolic Pulmonary Hypertension: Results From an International Prospective Registry.

Delcroix M, Lang I, Pepke-Zaba J, Jansa P, D'Armini AM, Snijder R, Bresser P, Torbicki A, Mellemkjaer S, Lewczuk J, Simkova I, Barberà JA, de Perrot M, Hoeper MM, Gaine S, Speich R, Gomez-Sanchez MA, Kovacs G, Jaïs X, Ambroz D, Treacy C, Morsolini M, Jenkins D, Lindner J, Dartevelle P, Mayer E, Simonneau G.

Circulation. 2016 Mar 1;133(9):859-71. doi: 10.1161/CIRCULATIONAHA.115.016522. Epub 2016 Jan 29.

PMID:
26826181
31.

Developments in pulmonary arterial hypertension-targeted therapy for chronic thromboembolic pulmonary hypertension.

Hadinnapola C, Pepke-Zaba J.

Expert Rev Respir Med. 2015 Oct;9(5):559-69. doi: 10.1586/17476348.2015.1085805. Review.

PMID:
26366805
32.

Bone morphogenetic protein receptor type II deficiency and increased inflammatory cytokine production. A gateway to pulmonary arterial hypertension.

Soon E, Crosby A, Southwood M, Yang P, Tajsic T, Toshner M, Appleby S, Shanahan CM, Bloch KD, Pepke-Zaba J, Upton P, Morrell NW.

Am J Respir Crit Care Med. 2015 Oct 1;192(7):859-72. doi: 10.1164/rccm.201408-1509OC.

33.

BMPR-II mutations promote pulmonary arterial hypertension via a hyperinflammatory response.

Soon E, Crosby A, Southwood M, Pepke-Zaba J, Upton P, Morrell N.

Clin Med (Lond). 2015 Jun;15 Suppl 3:s15. doi: 10.7861/clinmedicine.15-3-s15. Epub 2015 May 29. No abstract available.

PMID:
26026008
34.

The resistance-compliance product of the pulmonary circulation varies in health and pulmonary vascular disease.

Hadinnapola C, Li Q, Su L, Pepke-Zaba J, Toshner M.

Physiol Rep. 2015 Apr;3(4). pii: e12363. doi: 10.14814/phy2.12363.

35.

[Pulmonary arterial hypertension: epidemiology and registries].

McGoon MD, Benza RL, Escribano-Subias P, Jiang X, Miller DP, Peacock AJ, Pepke-Zaba J, Pulido T, Rich S, Rosenkranz S, Suissa S, Humbert M.

Turk Kardiyol Dern Ars. 2014 Oct;42 Suppl 1:67-77. Turkish.

36.

Presentation and management of pulmonary artery sarcoma.

Wong HH, Gounaris I, McCormack A, Berman M, Davidson D, Horan G, Pepke-Zaba J, Jenkins D, Earl HM, Hatcher HM.

Clin Sarcoma Res. 2015 Jan 21;5(1):3. doi: 10.1186/s13569-014-0019-2. eCollection 2015.

37.

Outcome of pulmonary endarterectomy in symptomatic chronic thromboembolic disease.

Taboada D, Pepke-Zaba J, Jenkins DP, Berman M, Treacy CM, Cannon JE, Toshner M, Dunning JJ, Ng C, Tsui SS, Sheares KK.

Eur Respir J. 2014 Dec;44(6):1635-45. doi: 10.1183/09031936.00050114. Epub 2014 Sep 18.

38.

Response to letters regarding article, "Anticoagulation and survival in pulmonary arterial hypertension: results from the Comparative, Prospective Registry of Newly Initiated Therapies for Pulmonary Hypertension (COMPERA)".

Olsson KM, Delcroix M, Ghofrani HA, Tiede H, Huscher D, Speich R, Grünig E, Staehler G, Rosenkranz S, Halank M, Held M, Lange TJ, Behr J, Klose H, Claussen M, Ewert R, Opitz CF, Vizza CD, Scelsi L, Vonk-Noordegraaf A, Kaemmerer H, Gibbs JS, Coghlan G, Pepke-Zaba J, Schulz U, Gorenflo M, Pittrow D, Hoeper MM.

Circulation. 2014 Sep 16;130(12):e110-2. doi: 10.1161/CIRCULATIONAHA.114.010921. No abstract available.

PMID:
25223780
40.

Right ventricular reverse remodeling after pulmonary endarterectomy: magnetic resonance imaging and clinical and right heart catheterization assessment.

Berman M, Gopalan D, Sharples L, Screaton N, Maccan C, Sheares K, Pepke-Zaba J, Dunning J, Tsui S, Jenkins DP.

Pulm Circ. 2014 Mar;4(1):36-44. doi: 10.1086/674884.

41.

Chronic thromboembolic pulmonary hypertension: time for research in pathophysiology to catch up with developments in treatment.

Toshner M, Pepke-Zaba J.

F1000Prime Rep. 2014 Jun 2;6:38. doi: 10.12703/P6-38. eCollection 2014. Review.

42.

Demographics, clinical characteristics, health resource utilization and cost of chronic thromboembolic pulmonary hypertension patients: retrospective results from six European countries.

Schweikert B, Pittrow D, Vizza CD, Pepke-Zaba J, Hoeper MM, Gabriel A, Berg J, Sikirica M.

BMC Health Serv Res. 2014 Jun 9;14:246. doi: 10.1186/1472-6963-14-246.

43.

Better off blue: BMPR-2 mutation, arteriovenous malformation, and pulmonary arterial hypertension.

Soon E, Southwood M, Sheares K, Pepke-Zaba J, Morrell NW.

Am J Respir Crit Care Med. 2014 Jun 1;189(11):1435-6. doi: 10.1164/rccm.201311-2019IM. No abstract available.

PMID:
24881940
44.

Maximal cardiac output determines 6 minutes walking distance in pulmonary hypertension.

Deboeck G, Taboada D, Hagan G, Treacy C, Page K, Sheares K, Naeije R, Pepke-Zaba J.

PLoS One. 2014 Mar 19;9(3):e92324. doi: 10.1371/journal.pone.0092324. eCollection 2014.

45.

Right ventricle functional assessment: have new techniques supplanted the old faithful conductance catheter?

McCabe C, White PA, Rana BS, Gopalan D, Agrawal B, Pepke-Zaba J, Hoole SP.

Cardiol Rev. 2014 Sep-Oct;22(5):233-40. doi: 10.1097/CRD.0000000000000020. Review.

PMID:
24621859
46.

Riociguat for pulmonary hypertension.

Cannon JE, Pepke-Zaba J.

Expert Rev Clin Pharmacol. 2014 May;7(3):259-70. doi: 10.1586/17512433.2014.893818. Epub 2014 Mar 3. Review.

PMID:
24580082
47.

Right ventricular dysfunction in chronic thromboembolic obstruction of the pulmonary artery: a pressure-volume study using the conductance catheter.

McCabe C, White PA, Hoole SP, Axell RG, Priest AN, Gopalan D, Taboada D, MacKenzie Ross R, Morrell NW, Shapiro LM, Pepke-Zaba J.

J Appl Physiol (1985). 2014 Feb 15;116(4):355-63. doi: 10.1152/japplphysiol.01123.2013. Epub 2013 Dec 19.

48.

Pulmonary arterial hypertension: epidemiology and registries.

McGoon MD, Benza RL, Escribano-Subias P, Jiang X, Miller DP, Peacock AJ, Pepke-Zaba J, Pulido T, Rich S, Rosenkranz S, Suissa S, Humbert M.

J Am Coll Cardiol. 2013 Dec 24;62(25 Suppl):D51-9. doi: 10.1016/j.jacc.2013.10.023. Review.

49.

Reply to "Letter to the editor: 'Pulsatile pulmonary artery pressure: are fluid-filled catheters accurate in pulmonary hypertension?'".

Mackenzie Ross RV, Toshner MR, Soon E, Naeije R, Pepke-Zaba J.

Am J Physiol Heart Circ Physiol. 2013 Dec 1;305(11):H1682. doi: 10.1152/ajpheart.00763.2013. No abstract available.

50.

Inefficient exercise gas exchange identifies pulmonary hypertension in chronic thromboembolic obstruction following pulmonary embolism.

McCabe C, Deboeck G, Harvey I, Ross RM, Gopalan D, Screaton N, Pepke-Zaba J.

Thromb Res. 2013;132(6):659-65. doi: 10.1016/j.thromres.2013.09.032. Epub 2013 Sep 27.

PMID:
24157082

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