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Items: 17

1.

Non-syndromic Mitral Valve Dysplasia Mutation Changes the Force Resilience and Interaction of Human Filamin A.

Haataja TJK, Bernardi RC, Lecointe S, Capoulade R, Merot J, Pentikäinen U.

Structure. 2019 Jan 2;27(1):102-112.e4. doi: 10.1016/j.str.2018.09.007. Epub 2018 Oct 18.

PMID:
30344108
2.

Structural and Functional Insights Into Lysostaphin-Substrate Interaction.

Tossavainen H, Raulinaitis V, Kauppinen L, Pentikäinen U, Maaheimo H, Permi P.

Front Mol Biosci. 2018 Jul 3;5:60. doi: 10.3389/fmolb.2018.00060. eCollection 2018.

3.

Skeletal Dysplasia Mutations Effect on Human Filamins' Structure and Mechanosensing.

Seppälä J, Bernardi RC, Haataja TJK, Hellman M, Pentikäinen OT, Schulten K, Permi P, Ylänne J, Pentikäinen U.

Sci Rep. 2017 Jun 26;7(1):4218. doi: 10.1038/s41598-017-04441-x.

4.

Flexible Structure of Peptide-Bound Filamin A Mechanosensor Domain Pair 20-21.

Seppälä J, Tossavainen H, Rodic N, Permi P, Pentikäinen U, Ylänne J.

PLoS One. 2015 Aug 31;10(8):e0136969. doi: 10.1371/journal.pone.0136969. eCollection 2015.

5.

A novel structural unit in the N-terminal region of filamins.

Sethi R, Seppälä J, Tossavainen H, Ylilauri M, Ruskamo S, Pentikäinen OT, Pentikäinen U, Permi P, Ylänne J.

J Biol Chem. 2014 Mar 21;289(12):8588-98. doi: 10.1074/jbc.M113.537456. Epub 2014 Jan 27.

6.

Molecular mechanism of T-cell protein tyrosine phosphatase (TCPTP) activation by mitoxantrone.

Ylilauri M, Mattila E, Nurminen EM, Käpylä J, Niinivehmas SP, Määttä JA, Pentikäinen U, Ivaska J, Pentikäinen OT.

Biochim Biophys Acta. 2013 Oct;1834(10):1988-97. doi: 10.1016/j.bbapap.2013.07.001. Epub 2013 Jul 12.

PMID:
23856547
7.

The C-terminal rod 2 fragment of filamin A forms a compact structure that can be extended.

Ruskamo S, Gilbert R, Hofmann G, Jiang P, Campbell ID, Ylänne J, Pentikäinen U.

Biochem J. 2012 Sep 1;446(2):261-9. doi: 10.1042/BJ20120361.

PMID:
22676060
8.

Assembly of a filamin four-domain fragment and the influence of splicing variant-1 on the structure.

Pentikäinen U, Jiang P, Takala H, Ruskamo S, Campbell ID, Ylänne J.

J Biol Chem. 2011 Jul 29;286(30):26921-30. doi: 10.1074/jbc.M110.195958. Epub 2011 Jun 2.

9.

Novel hydrazine molecules as tools to understand the flexibility of vascular adhesion protein-1 ligand-binding site: toward more selective inhibitors.

Nurminen EM, Pihlavisto M, Lázár L, Pentikäinen U, Fülöp F, Pentikäinen OT.

J Med Chem. 2011 Apr 14;54(7):2143-54. doi: 10.1021/jm200059p. Epub 2011 Mar 15.

PMID:
21405023
10.

Synthesis, in vitro activity, and three-dimensional quantitative structure-activity relationship of novel hydrazine inhibitors of human vascular adhesion protein-1.

Nurminen EM, Pihlavisto M, Lázár L, Szakonyi Z, Pentikäinen U, Fülöp F, Pentikäinen OT.

J Med Chem. 2010 Sep 9;53(17):6301-15. doi: 10.1021/jm100337z.

PMID:
20690686
11.

The regulation mechanism for the auto-inhibition of binding of human filamin A to integrin.

Pentikäinen U, Ylänne J.

J Mol Biol. 2009 Oct 30;393(3):644-57. doi: 10.1016/j.jmb.2009.08.035. Epub 2009 Aug 20.

PMID:
19699211
12.

Lennard-Jones Parameters for B3LYP/CHARMM27 QM/MM Modeling of Nucleic Acid Bases.

Pentikäinen U, Shaw KE, Senthilkumar K, Woods CJ, Mulholland AJ.

J Chem Theory Comput. 2009 Feb 10;5(2):396-410. doi: 10.1021/ct800135k.

PMID:
26610113
13.
15.

Vascular amine oxidases are needed for leukocyte extravasation into inflamed joints in vivo.

Marttila-Ichihara F, Smith DJ, Stolen C, Yegutkin GG, Elima K, Mercier N, Kiviranta R, Pihlavisto M, Alaranta S, Pentikäinen U, Pentikäinen O, Fülöp F, Jalkanen S, Salmi M.

Arthritis Rheum. 2006 Sep;54(9):2852-62.

16.

Determination of binding site residues responsible for the subunit selectivity of novel marine-derived compounds on kainate receptors.

Sanders JM, Pentikäinen OT, Settimo L, Pentikäinen U, Shoji M, Sasaki M, Sakai R, Johnson MS, Swanson GT.

Mol Pharmacol. 2006 Jun;69(6):1849-60. Epub 2006 Mar 14.

PMID:
16537793
17.

Subtype selectivity and flexibility of ionotropic glutamate receptors upon antagonist ligand binding.

Pentikäinen U, Settimo L, Johnson MS, Pentikäinen OT.

Org Biomol Chem. 2006 Mar 21;4(6):1058-70. Epub 2006 Jan 26.

PMID:
16525550

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