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Drug-Eluting Stents Compared With Bare Metal Stents for Stenting the Ductus Arteriosus in Infants With Ductal-Dependent Pulmonary Blood Flow.

Aggarwal V, Dhillon GS, Penny DJ, Gowda ST, Qureshi AM.

Am J Cardiol. 2019 Sep 15;124(6):952-959. doi: 10.1016/j.amjcard.2019.06.014. Epub 2019 Jun 26.


Incidentally identified genetic variants in arrhythmogenic right ventricular cardiomyopathy-associated genes among children undergoing exome sequencing reflect healthy population variation.

Headrick AT, Rosenfeld JA, Yang Y, Tunuguntla H, Allen HD, Penny DJ, Kim JJ, Landstrom AP.

Mol Genet Genomic Med. 2019 Jun;7(6):e593. doi: 10.1002/mgg3.593. Epub 2019 Apr 15.


Decreased Prevalence of Rheumatic Heart Disease Confirmed Among HIV-positive Youth.

Hovis IW, Namuyonga J, Kisitu GP, Ndagire E, Okello E, Longenecker CT, Sanyahumbi A, Sable CA, Penny DJ, Lwabi P, Kekitiinwa AR, Beaton A.

Pediatr Infect Dis J. 2019 Apr;38(4):406-409. doi: 10.1097/INF.0000000000002161.


Geoarchaeological evidence from Angkor, Cambodia, reveals a gradual decline rather than a catastrophic 15th-century collapse.

Penny D, Hall T, Evans D, Polkinghorne M.

Proc Natl Acad Sci U S A. 2019 Mar 12;116(11):4871-4876. doi: 10.1073/pnas.1821460116. Epub 2019 Feb 25.


Two-year evolution of latent rheumatic heart disease in Malawi.

Sanyahumbi A, Beaton A, Guffey D, Hosseinipour MC, Karlsten M, Minard CG, Penny DJ, Sable CA, Kazembe PN.

Congenit Heart Dis. 2019 Jul;14(4):614-618. doi: 10.1111/chd.12756. Epub 2019 Jan 31.


Genetic architecture of laterality defects revealed by whole exome sequencing.

Li AH, Hanchard NA, Azamian M, D'Alessandro LCA, Coban-Akdemir Z, Lopez KN, Hall NJ, Dickerson H, Nicosia A, Fernbach S, Boone PM, Gambin T, Karaca E, Gu S, Yuan B, Jhangiani SN, Doddapaneni H, Hu J, Dinh H, Jayaseelan J, Muzny D, Lalani S, Towbin J, Penny D, Fraser C, Martin J, Lupski JR, Gibbs RA, Boerwinkle E, Ware SM, Belmont JW.

Eur J Hum Genet. 2019 Apr;27(4):563-573. doi: 10.1038/s41431-018-0307-z. Epub 2019 Jan 8.


The demise of Angkor: Systemic vulnerability of urban infrastructure to climatic variations.

Penny D, Zachreson C, Fletcher R, Lau D, Lizier JT, Fischer N, Evans D, Pottier C, Prokopenko M.

Sci Adv. 2018 Oct 17;4(10):eaau4029. doi: 10.1126/sciadv.aau4029. eCollection 2018 Oct.


Re-evaluating the occupation history of Koh Ker, Cambodia, during the Angkor period: A palaeo-ecological approach.

Hall T, Penny D, Hamilton R.

PLoS One. 2018 Oct 10;13(10):e0203962. doi: 10.1371/journal.pone.0203962. eCollection 2018.


Relation Between Lead Exposure and Trends in Blood Pressure in Children.

Zachariah JP, Wang Y, Penny DJ, Baranowski T.

Am J Cardiol. 2018 Dec 1;122(11):1890-1895. doi: 10.1016/j.amjcard.2018.08.033. Epub 2018 Sep 7.


Strength in numbers: Crowdsourcing the most relevant literature in pediatric cardiology.

Knadler JJ, Penny DJ, Harris TH, Webb GD, Cabrera AG, Kyle WB.

Congenit Heart Dis. 2018 Sep;13(5):794-798. doi: 10.1111/chd.12669. Epub 2018 Sep 3. Review.


Clinical Consequences of Cardiomyopathy in Children With Biliary Atresia Requiring Liver Transplantation.

Gorgis NM, Kennedy C, Lam F, Thompson K, Coss-Bu J, Akcan Arikan A, Nguyen T, Hosek K, Miloh T, Karpen SJ, Penny DJ, Goss J, Desai MS.

Hepatology. 2019 Mar;69(3):1206-1218. doi: 10.1002/hep.30204. Epub 2019 Feb 17.


TGR5 activation induces cytoprotective changes in the heart and improves myocardial adaptability to physiologic, inotropic, and pressure-induced stress in mice.

Eblimit Z, Thevananther S, Karpen SJ, Taegtmeyer H, Moore DD, Adorini L, Penny DJ, Desai MS.

Cardiovasc Ther. 2018 Oct;36(5):e12462. doi: 10.1111/1755-5922.12462. Epub 2018 Aug 22.


Membrane cholesterol modulates STEAP2 conformation during dynamic intracellular trafficking processes leading to broad subcellular distribution.

Hasegawa H, Li C, Alba BM, Penny DM, Xia Z, Dayao MR, Li P, Zhang J, Zhou J, Lim D, Murawsky CM, Lim AC.

Exp Cell Res. 2018 Sep 15;370(2):208-226. doi: 10.1016/j.yexcr.2018.06.022. Epub 2018 Jun 27.


Design and rationale of the Fontan Udenafil Exercise Longitudinal (FUEL) trial.

Goldberg DJ, Zak V, Goldstein BH, McCrindle BW, Menon SC, Schumacher KR, Payne RM, Rhodes J, McHugh KE, Penny DJ, Trachtenberg F, Hamstra MS, Richmond ME, Frommelt PC, Files MD, Yeager JL, Pemberton VL, Stylianou MP, Pearson GD, Paridon SM; Pediatric Heart Network Investigators.

Am Heart J. 2018 Jul;201:1-8. doi: 10.1016/j.ahj.2018.03.015. Epub 2018 Apr 3. Review.


Improving phylogenetic inference of core Chlorophyta using chloroplast sequences with strong phylogenetic signals and heterogeneous models.

Fang L, Leliaert F, Novis PM, Zhang Z, Zhu H, Liu G, Penny D, Zhong B.

Mol Phylogenet Evol. 2018 Oct;127:248-255. doi: 10.1016/j.ympev.2018.06.006. Epub 2018 Jun 8.


Functional classification of heart failure before and after implementing a healthcare transition program for youth and young adults transferring from a pediatric to an adult congenital heart disease clinics.

Hergenroeder AC, Moodie DS, Penny DJ, Wiemann CM, Sanchez-Fournier B, Moore LK, Head J.

Congenit Heart Dis. 2018 Jul;13(4):548-553. doi: 10.1111/chd.12604. Epub 2018 Mar 15.


Amino acid-level signal-to-noise analysis of incidentally identified variants in genes associated with long QT syndrome during pediatric whole exome sequencing reflects background genetic noise.

Landstrom AP, Fernandez E, Rosenfeld JA, Yang Y, Dailey-Schwartz AL, Miyake CY, Allen HD, Penny DJ, Kim JJ.

Heart Rhythm. 2018 Jul;15(7):1042-1050. doi: 10.1016/j.hrthm.2018.02.031. Epub 2018 Mar 2.


Major influence of a 'smoke and mirrors' effect caused by wave reflection on early diastolic coronary arterial wave intensity.

Mynard JP, Penny DJ, Smolich JJ.

J Physiol. 2018 Mar 15;596(6):993-1017. doi: 10.1113/JP274710. Epub 2018 Feb 13.


Effects of Pressure and pH on the Hydrolysis of Cytosine: Implications for Nucleotide Stability around Deep-Sea Black Smokers.

Lepper CP, Williams MAK, Penny D, Edwards PJB, Jameson GB.

Chembiochem. 2018 Mar 16;19(6):540-544. doi: 10.1002/cbic.201700555. Epub 2018 Feb 6.


Whole exome sequencing in 342 congenital cardiac left sided lesion cases reveals extensive genetic heterogeneity and complex inheritance patterns.

Li AH, Hanchard NA, Furthner D, Fernbach S, Azamian M, Nicosia A, Rosenfeld J, Muzny D, D'Alessandro LCA, Morris S, Jhangiani S, Parekh DR, Franklin WJ, Lewin M, Towbin JA, Penny DJ, Fraser CD, Martin JF, Eng C, Lupski JR, Gibbs RA, Boerwinkle E, Belmont JW.

Genome Med. 2017 Oct 31;9(1):95. doi: 10.1186/s13073-017-0482-5.


Development of quality metrics for ambulatory pediatric cardiology: Transposition of the great arteries after arterial switch operation.

Baker-Smith CM, Carlson K, Ettedgui J, Tsuda T, Jayakumar KA, Park M, Tede N, Uzark K, Fleishman C, Connuck D, Likes M, Penny DJ.

Congenit Heart Dis. 2018 Jan;13(1):52-58. doi: 10.1111/chd.12540. Epub 2017 Oct 2. Review.


A computational study of the Fontan circulation with fenestration or hepatic vein exclusion.

Puelz C, Acosta S, Rivière B, Penny DJ, Brady KM, Rusin CG.

Comput Biol Med. 2017 Oct 1;89:405-418. doi: 10.1016/j.compbiomed.2017.08.024. Epub 2017 Aug 25.


Metal enrichment in estuarine sediments proximal to acid sulfate soils as a novel palaeodrought proxy.

Job T, Penny D, Hua Q.

Sci Total Environ. 2018 Jan 15;612:247-256. doi: 10.1016/j.scitotenv.2017.08.157. Epub 2017 Sep 1.


An effective model of cerebrovascular pressure reactivity and blood flow autoregulation.

Acosta S, Penny DJ, Brady KM, Rusin CG.

Microvasc Res. 2018 Jan;115:34-43. doi: 10.1016/j.mvr.2017.08.006. Epub 2017 Aug 25.


Phylogenetics: Tertiary protein structures needed.

Penny D.

Nat Ecol Evol. 2017 Feb 13;1(3):80. doi: 10.1038/s41559-017-0080. No abstract available.


Cardiovascular adaptation to the Fontan circulation.

Veldtman GR, Opotowsky AR, Wittekind SG, Rychik J, Penny DJ, Fogel M, Marino BS, Gewillig M.

Congenit Heart Dis. 2017 Dec;12(6):699-710. doi: 10.1111/chd.12526. Epub 2017 Aug 10. Review.


Cardiovascular mechanics in the early stages of pulmonary hypertension: a computational study.

Acosta S, Puelz C, Rivière B, Penny DJ, Brady KM, Rusin CG.

Biomech Model Mechanobiol. 2017 Dec;16(6):2093-2112. doi: 10.1007/s10237-017-0940-4. Epub 2017 Jul 21.


Speaking to children and their families about congenital heart disease: Ushering in a new era of healthcare literacy.

Penny DJ.

Congenit Heart Dis. 2017 May;12(3):241. doi: 10.1111/chd.12474. No abstract available.


Interpreting Incidentally Identified Variants in Genes Associated With Catecholaminergic Polymorphic Ventricular Tachycardia in a Large Cohort of Clinical Whole-Exome Genetic Test Referrals.

Landstrom AP, Dailey-Schwartz AL, Rosenfeld JA, Yang Y, McLean MJ, Miyake CY, Valdes SO, Fan Y, Allen HD, Penny DJ, Kim JJ.

Circ Arrhythm Electrophysiol. 2017 Apr;10(4). pii: e004742. doi: 10.1161/CIRCEP.116.004742.


Development of Quality Metrics in Ambulatory Pediatric Cardiology.

Chowdhury D, Gurvitz M, Marelli A, Anderson J, Baker-Smith C, Diab KA, Edwards TC, Hougen T, Jedeikin R, Johnson JN, Karpawich P, Lai W, Lu JC, Mitchell S, Newburger JW, Penny DJ, Portman MA, Satou G, Teitel D, Villafane J, Williams R, Jenkins K; American College of Cardiology’s Adult Congenital and Pediatric Cardiology Section’s Ambulatory Pediatric Cardiology Quality Metrics Working Group.

J Am Coll Cardiol. 2017 Feb 7;69(5):541-555. doi: 10.1016/j.jacc.2016.11.043. Review.


Task shifting to clinical officer-led echocardiography screening for detecting rheumatic heart disease in Malawi, Africa.

Sims Sanyahumbi A, Sable CA, Karlsten M, Hosseinipour MC, Kazembe PN, Minard CG, Penny DJ.

Cardiol Young. 2017 Aug;27(6):1133-1139. doi: 10.1017/S1047951116002511. Epub 2016 Dec 19.


A genome-wide association study of congenital cardiovascular left-sided lesions shows association with a locus on chromosome 20.

Hanchard NA, Swaminathan S, Bucasas K, Furthner D, Fernbach S, Azamian MS, Wang X, Lewin M, Towbin JA, D'Alessandro LC, Morris SA, Dreyer W, Denfield S, Ayres NA, Franklin WJ, Justino H, Lantin-Hermoso MR, Ocampo EC, Santos AB, Parekh D, Moodie D, Jeewa A, Lawrence E, Allen HD, Penny DJ, Fraser CD, Lupski JR, Popoola M, Wadhwa L, Brook JD, Bu'Lock FA, Bhattacharya S, Lalani SR, Zender GA, Fitzgerald-Butt SM, Bowman J, Corsmeier D, White P, Lecerf K, Zapata G, Hernandez P, Goodship JA, Garg V, Keavney BD, Leal SM, Cordell HJ, Belmont JW, McBride KL.

Hum Mol Genet. 2016 Jun 1;25(11):2331-2341. Epub 2016 Mar 9.


Bile acid excess induces cardiomyopathy and metabolic dysfunctions in the heart.

Desai MS, Mathur B, Eblimit Z, Vasquez H, Taegtmeyer H, Karpen SJ, Penny DJ, Moore DD, Anakk S.

Hepatology. 2017 Jan;65(1):189-201. doi: 10.1002/hep.28890. Epub 2016 Nov 29.


A Novel Electrocardiogram Algorithm Utilizing ST-Segment Instability for Detection of Cardiopulmonary Arrest in Single Ventricle Physiology: A Retrospective Study.

Vu EL, Rusin CG, Penny DJ, Kibler KK, Easley RB, Smith B, Andropoulos D, Brady K.

Pediatr Crit Care Med. 2017 Jan;18(1):44-53. doi: 10.1097/PCC.0000000000000980.


Global Perspectives On Pediatric Cardiac Critical Care.

Penny DJ.

Pediatr Crit Care Med. 2016 Aug;17(8 Suppl 1):S388-93. doi: 10.1097/PCC.0000000000000784. Review.


Clinical-Physiological Considerations in Patients Undergoing Staged Palliation for a Functionally Single Ventricle.

Penny DJ, Krishnamurthy R.

Pediatr Crit Care Med. 2016 Aug;17(8 Suppl 1):S347-55. doi: 10.1097/PCC.0000000000000821. Review.


Cardiopulmonary Interactions.

Bronicki RA, Penny DJ, Anas NG, Fuhrman B.

Pediatr Crit Care Med. 2016 Aug;17(8 Suppl 1):S182-93. doi: 10.1097/PCC.0000000000000829. Review.


Function of the Left and Right Ventricles and the Interactions Between Them.

Penny DJ, Redington AN.

Pediatr Crit Care Med. 2016 Aug;17(8 Suppl 1):S112-8. doi: 10.1097/PCC.0000000000000794. Review.


Prediction of imminent, severe deterioration of children with parallel circulations using real-time processing of physiologic data.

Rusin CG, Acosta SI, Shekerdemian LS, Vu EL, Bavare AC, Myers RB, Patterson LW, Brady KM, Penny DJ.

J Thorac Cardiovasc Surg. 2016 Jul;152(1):171-7. doi: 10.1016/j.jtcvs.2016.03.083. Epub 2016 Apr 16.


Does the Ribosome Challenge our Understanding of the RNA World?

Poole AM, Jeffares DC, Hoeppner MP, Penny D.

J Mol Evol. 2016 Jan;82(1):1-4. No abstract available.


School and Community Screening Shows Malawi, Africa, to Have a High Prevalence of Latent Rheumatic Heart Disease.

Sims Sanyahumbi A, Sable CA, Beaton A, Chimalizeni Y, Guffey D, Hosseinipour M, Karlsten M, Kazembe PN, Kennedy N, Minard CG, Penny DJ.

Congenit Heart Dis. 2016 Dec;11(6):615-621. doi: 10.1111/chd.12353. Epub 2016 Mar 31.


Variability in Treatment of Post-coarctectomy Hypertension: A Multicenter Study.

Moffett BS, Penny DJ.

Pediatr Cardiol. 2016 Apr;37(4):772-7. doi: 10.1007/s00246-016-1349-z. Epub 2016 Feb 20.


Chloroplast Phylogenomic Inference of Green Algae Relationships.

Sun L, Fang L, Zhang Z, Chang X, Penny D, Zhong B.

Sci Rep. 2016 Feb 5;6:20528. doi: 10.1038/srep20528.


Novel homozygous BMP9 nonsense mutation causes pulmonary arterial hypertension: a case report.

Wang G, Fan R, Ji R, Zou W, Penny DJ, Varghese NP, Fan Y.

BMC Pulm Med. 2016 Jan 22;16:17. doi: 10.1186/s12890-016-0183-7.


Assessing ST Segment Changes and Ischemia During Exercise Stress Testing in Patients with Hypoplastic Left Heart Syndrome and Fontan Palliation.

Kyle WB, Denfield SW, Valdes SO, Penny DJ, Bolin EH, Lopez KN.

Pediatr Cardiol. 2016 Mar;37(3):545-51. doi: 10.1007/s00246-015-1312-4. Epub 2016 Jan 4.


Does the Ribosome Challenge our Understanding of the RNA World?

Poole AM, Jeffares DC, Hoeppner MP, Penny D.

J Mol Evol. 2016 Jan;82(1):1-4. doi: 10.1007/s00239-015-9720-x. Epub 2015 Nov 18.


New Zealand Passerines Help Clarify the Diversification of Major Songbird Lineages during the Oligocene.

Gibb GC, England R, Hartig G, McLenachan PA, Taylor Smith BL, McComish BJ, Cooper A, Penny D.

Genome Biol Evol. 2015 Oct 15;7(11):2983-95. doi: 10.1093/gbe/evv196.


The Origin of Land Plants: A Phylogenomic Perspective.

Zhong B, Sun L, Penny D.

Evol Bioinform Online. 2015 Jul 8;11:137-41. doi: 10.4137/EBO.S29089. eCollection 2015. Review.


Epigenetics, Darwin, and Lamarck.

Penny D.

Genome Biol Evol. 2015 May 29;7(6):1758-60. doi: 10.1093/gbe/evv107.

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