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Items: 1 to 50 of 61

1.

The dynamic and stress-adaptive signaling hub of 14-3-3: emerging mechanisms of regulation and context-dependent protein-protein interactions.

Pennington KL, Chan TY, Torres MP, Andersen JL.

Oncogene. 2018 Jun 18. doi: 10.1038/s41388-018-0348-3. [Epub ahead of print] Review.

PMID:
29915393
2.

Epithelium Lining Rat Renal Papilla: Nomenclature and Association with Chronic Progressive Nephropathy (CPN).

Souza NP, Hard GC, Arnold LL, Foster KW, Pennington KL, Cohen SM.

Toxicol Pathol. 2018 Apr;46(3):266-272. doi: 10.1177/0192623318762694. Epub 2018 Mar 4.

PMID:
29504493
3.

Orally administered nicotine effects on rat urinary bladder proliferation and carcinogenesis.

Suzuki S, Cohen SM, Arnold LL, Kato H, Fuji S, Pennington KL, Nagayasu Y, Naiki-Ito A, Yamashita Y, Takahashi S.

Toxicology. 2018 Apr 1;398-399:31-40. doi: 10.1016/j.tox.2018.02.008. Epub 2018 Mar 6.

PMID:
29501575
4.

Effect of polyhexamethylene biguanide on rat liver.

Chowdhury A, Arnold LL, Wang Z, Pennington KL, Dodmane P, Farragut-Cardoso AP, Klaunig JE, Cros D, Creppy EE, Cohen SM.

Toxicol Lett. 2018 Mar 15;285:94-103. doi: 10.1016/j.toxlet.2017.12.032. Epub 2018 Jan 2.

PMID:
29305328
5.

Low-dose dose-response for reduced cell viability after exposure of human keratinocyte (HEK001) cells to arsenite.

Bogen KT, Arnold LL, Chowdhury A, Pennington KL, Cohen SM.

Toxicol Rep. 2016 Dec 14;4:32-38. doi: 10.1016/j.toxrep.2016.12.003. eCollection 2017.

6.

Epidemiology of age-related macular degeneration (AMD): associations with cardiovascular disease phenotypes and lipid factors.

Pennington KL, DeAngelis MM.

Eye Vis (Lond). 2016 Dec 22;3:34. doi: 10.1186/s40662-016-0063-5. eCollection 2016. Review.

7.

Suggestive evidence for the induction of colonic aberrant crypts in mice fed sodium nitrite.

Zhou L, Zahid M, Anwar MM, Pennington KL, Cohen SM, Wisecarver JL, Shostrom V, Mirvish SS.

Nutr Cancer. 2016;68(1):105-12. doi: 10.1080/01635581.2016.1102298. Epub 2015 Dec 23.

PMID:
26699517
8.

Effect of trivalent arsenicals on cell proliferation in mouse and human microvascular endothelial cells.

Dodmane PR, Arnold LL, Pennington KL, Singh RK, Cardoso APF, Cohen SM.

Toxicol Rep. 2015 May 21;2:833-837. doi: 10.1016/j.toxrep.2015.05.009. eCollection 2015.

9.

Epigenetic Mechanisms of the Aging Human Retina.

Pennington KL, DeAngelis MM.

J Exp Neurosci. 2016 Feb 3;9(Suppl 2):51-79. doi: 10.4137/JEN.S25513. eCollection 2015. Review.

10.

Orally administered nicotine induces urothelial hyperplasia in rats and mice.

Dodmane PR, Arnold LL, Pennington KL, Cohen SM.

Toxicology. 2014 Jan 6;315:49-54. doi: 10.1016/j.tox.2013.11.002. Epub 2013 Nov 19.

PMID:
24269753
11.

Diuron metabolites and urothelial cytotoxicity: in vivo, in vitro and molecular approaches.

Da Rocha MS, Arnold LL, Dodmane PR, Pennington KL, Qiu F, De Camargo JL, Cohen SM.

Toxicology. 2013 Dec 15;314(2-3):238-46. doi: 10.1016/j.tox.2013.10.005. Epub 2013 Oct 27.

PMID:
24172598
12.

Characterization of intracellular inclusions in the urothelium of mice exposed to inorganic arsenic.

Dodmane PR, Arnold LL, Muirhead DE, Suzuki S, Yokohira M, Pennington KL, Dave BJ, Lu X, Le XC, Cohen SM.

Toxicol Sci. 2014 Jan;137(1):36-46. doi: 10.1093/toxsci/kft227. Epub 2013 Oct 4.

PMID:
24097667
13.

Time course of urothelial changes in rats and mice orally administered arsenite.

Arnold LL, Suzuki S, Yokohira M, Kakiuchi-Kiyota S, Pennington KL, Cohen SM.

Toxicol Pathol. 2014 Jul;42(5):855-62. doi: 10.1177/0192623313489778. Epub 2013 May 20.

PMID:
23690446
14.

Holo-TFIID controls the magnitude of a transcription burst and fine-tuning of transcription.

Pennington KL, Marr SK, Chirn GW, Marr MT 2nd.

Proc Natl Acad Sci U S A. 2013 May 7;110(19):7678-83. doi: 10.1073/pnas.1221712110. Epub 2013 Apr 22.

15.

Effect of dietary treatment with dimethylarsinous acid (DMA(III)) on the urinary bladder epithelium of arsenic (+3 oxidation state) methyltransferase (As3mt) knockout and C57BL/6 wild type female mice.

Dodmane PR, Arnold LL, Pennington KL, Thomas DJ, Cohen SM.

Toxicology. 2013 Mar 8;305:130-5. doi: 10.1016/j.tox.2013.01.015. Epub 2013 Jan 30.

PMID:
23376817
16.

Evaluation of expression profiles of hematopoietic stem cell, endothelial cell, and myeloid cell antigens in spontaneous and chemically induced hemangiosarcomas and hemangiomas in mice.

Kakiuchi-Kiyota S, Crabbs TA, Arnold LL, Pennington KL, Cook JC, Malarkey DE, Cohen SM.

Toxicol Pathol. 2013 Jul;41(5):709-21. doi: 10.1177/0192623312464309. Epub 2012 Nov 2.

PMID:
23125116
17.

Diuron-induced rat bladder epithelial cytotoxicity.

Da Rocha MS, Arnold LL, Pennington KL, Muirhead D, Dodmane PR, Anwar MM, Battalora M, De Camargo JL, Cohen SM.

Toxicol Sci. 2012 Dec;130(2):281-8. doi: 10.1093/toxsci/kfs256. Epub 2012 Aug 24.

PMID:
22923491
18.

Effects of co-administration of dietary sodium arsenate and 2,3-dimercaptopropane-1-sulfonic acid (DMPS) on the rat bladder epithelium.

Suzuki S, Arnold LL, Pennington KL, Kakiuchi-Kiyota S, Chen B, Lu X, Le XC, Cohen SM.

Toxicology. 2012 Sep 28;299(2-3):155-9. doi: 10.1016/j.tox.2012.05.019. Epub 2012 Jun 1.

PMID:
22664484
19.

Fractionated radioimmunotherapy with (90) Y-clivatuzumab tetraxetan and low-dose gemcitabine is active in advanced pancreatic cancer: A phase 1 trial.

Ocean AJ, Pennington KL, Guarino MJ, Sheikh A, Bekaii-Saab T, Serafini AN, Lee D, Sung MW, Gulec SA, Goldsmith SJ, Manzone T, Holt M, O'Neil BH, Hall N, Montero AJ, Kauh J, Gold DV, Horne H, Wegener WA, Goldenberg DM.

Cancer. 2012 Nov 15;118(22):5497-506. doi: 10.1002/cncr.27592. Epub 2012 May 8.

20.

Mode of action of pulegone on the urinary bladder of F344 rats.

Da Rocha MS, Dodmane PR, Arnold LL, Pennington KL, Anwar MM, Adams BR, Taylor SV, Wermes C, Adams TB, Cohen SM.

Toxicol Sci. 2012 Jul;128(1):1-8. doi: 10.1093/toxsci/kfs135. Epub 2012 Apr 12.

PMID:
22499580
21.

Efficient metal-specific transcription activation by Drosophila MTF-1 requires conserved cysteine residues in the carboxy-terminal domain.

Marr SK, Pennington KL, Marr MT.

Biochim Biophys Acta. 2012 Aug;1819(8):902-12. doi: 10.1016/j.bbagrm.2012.03.005. Epub 2012 Mar 28.

22.

Evaluation of direct and indirect effects of the PPARĪ³ agonist troglitazone on mouse endothelial cell proliferation.

Kakiuchi-Kiyota S, Arnold LL, Yokohira M, Koza-Taylor P, Suzuki S, Varney M, Pennington KL, Cohen SM.

Toxicol Pathol. 2011 Dec;39(7):1032-45. doi: 10.1177/0192623311422080. Epub 2011 Sep 21.

PMID:
21937740
23.

Evaluation of PPARĪ³ agonists on rodent endothelial cell proliferation.

Kakiuchi-Kiyota S, Arnold LL, Yokohira M, Suzuki S, Pennington KL, Cohen SM.

Toxicology. 2011 Sep 5;287(1-3):91-8. doi: 10.1016/j.tox.2011.05.019. Epub 2011 Jun 12.

PMID:
21684317
24.

Treatment of advanced pancreatic carcinoma with 90Y-Clivatuzumab Tetraxetan: a phase I single-dose escalation trial.

Gulec SA, Cohen SJ, Pennington KL, Zuckier LS, Hauke RJ, Horne H, Wegener WA, Teoh N, Gold DV, Sharkey RM, Goldenberg DM.

Clin Cancer Res. 2011 Jun 15;17(12):4091-100. doi: 10.1158/1078-0432.CCR-10-2579. Epub 2011 Apr 28.

25.

Effect of sodium arsenite dose administered in the drinking water on the urinary bladder epithelium of female arsenic (+3 oxidation state) methyltransferase knockout mice.

Yokohira M, Arnold LL, Pennington KL, Suzuki S, Kakiuchi-Kiyota S, Herbin-Davis K, Thomas DJ, Cohen SM.

Toxicol Sci. 2011 Jun;121(2):257-66. doi: 10.1093/toxsci/kfr051. Epub 2011 Mar 7.

PMID:
21385732
26.

The effects of oral treatment with transfluthrin on the urothelium of rats and its metabolite, tetrafluorobenzoic acid on urothelial cells in vitro.

Yokohira M, Arnold LL, Lautraite S, Sheets L, Wason S, Stahl B, Eigenberg D, Pennington KL, Kakiuchi-Kiyota S, Cohen SM.

Food Chem Toxicol. 2011 Jun;49(6):1215-23. doi: 10.1016/j.fct.2011.02.022. Epub 2011 Mar 4.

PMID:
21377505
27.

Severe systemic toxicity and urinary bladder cytotoxicity and regenerative hyperplasia induced by arsenite in arsenic (+3 oxidation state) methyltransferase knockout mice. A preliminary report.

Yokohira M, Arnold LL, Pennington KL, Suzuki S, Kakiuchi-Kiyota S, Herbin-Davis K, Thomas DJ, Cohen SM.

Toxicol Appl Pharmacol. 2010 Jul;246(1-2):1-7. doi: 10.1016/j.taap.2010.04.013. Epub 2010 Apr 25.

PMID:
20423714
28.

Dietary administration of sodium arsenite to rats: relations between dose and urinary concentrations of methylated and thio-metabolites and effects on the rat urinary bladder epithelium.

Suzuki S, Arnold LL, Pennington KL, Chen B, Naranmandura H, Le XC, Cohen SM.

Toxicol Appl Pharmacol. 2010 Apr 15;244(2):99-105. doi: 10.1016/j.taap.2009.12.026. Epub 2010 Jan 4.

PMID:
20045014
29.

Effects of pioglitazone, a peroxisome proliferator-activated receptor gamma agonist, on the urine and urothelium of the rat.

Suzuki S, Arnold LL, Pennington KL, Kakiuchi-Kiyota S, Wei M, Wanibuchi H, Cohen SM.

Toxicol Sci. 2010 Feb;113(2):349-57. doi: 10.1093/toxsci/kfp256. Epub 2009 Oct 25.

PMID:
19858066
30.

Effects of an epidermal growth factor receptor inhibitor on arsenic associated toxicity in the rat bladder epithelium.

Suzuki S, Arnold LL, Pennington KL, Chen B, Le XC, Cohen SM.

Toxicol Lett. 2009 Jun 1;187(2):124-9. doi: 10.1016/j.toxlet.2009.02.013. Epub 2009 Mar 3.

PMID:
19429254
31.

Effects of co-administration of dietary sodium arsenite and an NADPH oxidase inhibitor on the rat bladder epithelium.

Suzuki S, Arnold LL, Pennington KL, Kakiuchi-Kiyota S, Cohen SM.

Toxicology. 2009 Jun 30;261(1-2):41-6. doi: 10.1016/j.tox.2009.04.042. Epub 2009 May 3.

PMID:
19397947
32.

Effects of the PPARgamma agonist troglitazone on endothelial cells in vivo and in vitro: differences between human and mouse.

Kakiuchi-Kiyota S, Vetro JA, Suzuki S, Varney ML, Han HY, Nascimento M, Pennington KL, Arnold LL, Singh RK, Cohen SM.

Toxicol Appl Pharmacol. 2009 May 15;237(1):83-90. doi: 10.1016/j.taap.2009.02.028. Epub 2009 Mar 11. Erratum in: Toxicol Appl Pharmacol. 2011 Jun 15;253(3):290.

PMID:
19285096
33.

Inorganic arsenic-induced intramitochondrial granules in mouse urothelium.

Suzuki S, Arnold LL, Muirhead D, Lu X, Le XC, Bjork JA, Wallace KB, Ohnishi T, Kakiuchi-Kiyota S, Pennington KL, Cohen SM.

Toxicol Pathol. 2008 Dec;36(7):999-1005. doi: 10.1177/0192623308327408.

PMID:
19126794
34.

Factors related to long-term renal transplant function in children.

Ellis EN, Martz K, Talley L, Ilyas M, Pennington KL, Blaszak RT.

Pediatr Nephrol. 2008 Jul;23(7):1149-55. doi: 10.1007/s00467-008-0779-0. Epub 2008 Feb 27.

PMID:
18301925
35.

Genetic control of estrogen action in the rat: mapping of QTLs that impact pituitary lactotroph hyperplasia in a BN x ACI intercross.

Shull JD, Lachel CM, Murrin CR, Pennington KL, Schaffer BS, Strecker TE, Gould KA.

Mamm Genome. 2007 Sep;18(9):657-69. Epub 2007 Sep 18.

PMID:
17876666
36.

Genetic bases of estrogen-induced tumorigenesis in the rat: mapping of loci controlling susceptibility to mammary cancer in a Brown Norway x ACI intercross.

Schaffer BS, Lachel CM, Pennington KL, Murrin CR, Strecker TE, Tochacek M, Gould KA, Meza JL, McComb RD, Shull JD.

Cancer Res. 2006 Aug 1;66(15):7793-800.

37.

Genetic bases of renal agenesis in the ACI rat: mapping of Renag1 to chromosome 14.

Shull JD, Lachel CM, Strecker TE, Spady TJ, Tochacek M, Pennington KL, Murrin CR, Meza JL, Schaffer BS, Flood LA, Gould KA.

Mamm Genome. 2006 Jul;17(7):751-9. Epub 2006 Jul 14.

PMID:
16845468
38.

Genetic mapping of Eutr1, a locus controlling E2-induced pyometritis in the Brown Norway rat, to RNO5.

Gould KA, Pandey J, Lachel CM, Murrin CR, Flood LA, Pennington KL, Schaffer BS, Tochacek M, McComb RD, Meza JL, Wendell DL, Shull JD.

Mamm Genome. 2005 Nov;16(11):854-64. Epub 2005 Nov 11.

PMID:
16284801
39.

Genetic bases of estrogen-induced pituitary tumorigenesis: identification of genetic loci determining estrogen-induced pituitary growth in reciprocal crosses between the ACI and Copenhagen rat strains.

Strecker TE, Spady TJ, Schaffer BS, Gould KA, Kaufman AE, Shen F, McLaughlin MT, Pennington KL, Meza JL, Shull JD.

Genetics. 2005 Apr;169(4):2189-97. Epub 2005 Jan 31.

40.

Genetic determination of susceptibility to estrogen-induced mammary cancer in the ACI rat: mapping of Emca1 and Emca2 to chromosomes 5 and 18.

Gould KA, Tochacek M, Schaffer BS, Reindl TM, Murrin CR, Lachel CM, VanderWoude EA, Pennington KL, Flood LA, Bynote KK, Meza JL, Newton MA, Shull JD.

Genetics. 2004 Dec;168(4):2113-25.

41.

Rat strain specific attenuation of estrogen action in the anterior pituitary gland by dietary energy restriction.

Harvell DM, Buckles LK, Gould KA, Pennington KL, McComb RD, Shull JD.

Endocrine. 2003 Jul;21(2):175-83.

PMID:
12897383
42.

Dietary energy restriction inhibits estrogen-induced mammary, but not pituitary, tumorigenesis in the ACI rat.

Harvell DM, Strecker TE, Xie B, Pennington KL, McComb RD, Shull JD.

Carcinogenesis. 2002 Jan;23(1):161-9.

PMID:
11756237
43.

Susceptibility to estrogen-induced mammary cancer segregates as an incompletely dominant phenotype in reciprocal crosses between the ACI and Copenhagen rat strains.

Shull JD, Pennington KL, Reindl TM, Snyder MC, Strecker TE, Spady TJ, Tochacek M, McComb RD.

Endocrinology. 2001 Dec;142(12):5124-30.

PMID:
11713205
44.

Rat strain-specific actions of 17beta-estradiol in the mammary gland: correlation between estrogen-induced lobuloalveolar hyperplasia and susceptibility to estrogen-induced mammary cancers.

Harvell DM, Strecker TE, Tochacek M, Xie B, Pennington KL, McComb RD, Roy SK, Shull JD.

Proc Natl Acad Sci U S A. 2000 Mar 14;97(6):2779-84.

45.

Estrogen-induced pituitary tumor development in the ACI rat not inhibited by dietary energy restriction.

Spady TJ, Pennington KL, McComb RD, Birt DF, Shull JD.

Mol Carcinog. 1999 Dec;26(4):239-53.

PMID:
10569801
46.
47.

Modulation of estrogen action in the rat pituitary and mammary glands by dietary energy consumption.

Spady TJ, Harvell DM, Lemus-Wilson A, Strecker TE, Pennington KL, Vander Woude EA, Birt DF, McComb RD, Shull JD.

J Nutr. 1999 Feb;129(2S Suppl):587S-590S. doi: 10.1093/jn/129.2.587S.

PMID:
10064338
48.

Estrogen induction of prolactin-producing pituitary tumors in the Fischer 344 rat: modulation by dietary-energy but not protein consumption.

Shull JD, Birt DF, McComb RD, Spady TJ, Pennington KL, Shaw-Bruha CM.

Mol Carcinog. 1998 Oct;23(2):96-105.

PMID:
9808163
49.

Dietary energy restriction abolishes development of prolactin-producing pituitary tumors in Fischer 344 rats treated with 17beta-estradiol.

Spady TJ, Lemus-Wilson AM, Pennington KL, Blackwood DJ, Paschall TM, Birt DF, McComb RD, Shull JD.

Mol Carcinog. 1998 Oct;23(2):86-95.

PMID:
9808162
50.

Identification in the rat prolactin gene of sequences homologous to the distal promoter of the human prolactin gene.

Shaw-Bruha CM, Pennington KL, Shull JD.

Biochim Biophys Acta. 1998 Nov 8;1442(2-3):304-13.

PMID:
9804978

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