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Association of Titin-Truncating Genetic Variants With Life-threatening Cardiac Arrhythmias in Patients With Dilated Cardiomyopathy and Implanted Defibrillators.

Corden B, Jarman J, Whiffin N, Tayal U, Buchan R, Sehmi J, Harper A, Midwinter W, Lascelles K, Markides V, Mason M, Baksi J, Pantazis A, Pennell DJ, Barton PJ, Prasad SK, Wong T, Cook SA, Ware JS.

JAMA Netw Open. 2019 Jun 5;2(6):e196520. doi: 10.1001/jamanetworkopen.2019.6520.


The feasibility of a novel limited field of view spiral cine DENSE sequence to assess myocardial strain in dilated cardiomyopathy.

Tayal U, Wage R, Ferreira PF, Nielles-Vallespin S, Epstein FH, Auger D, Zhong X, Pennell DJ, Firmin DN, Scott AD, Prasad SK.

MAGMA. 2019 Jun;32(3):317-329. doi: 10.1007/s10334-019-00735-5. Epub 2019 Jan 29.


Microvascular Dysfunction in Dilated Cardiomyopathy: A Quantitative Stress Perfusion Cardiovascular Magnetic Resonance Study.

Gulati A, Ismail TF, Ali A, Hsu LY, Gonçalves C, Ismail NA, Krishnathasan K, Davendralingam N, Ferreira P, Halliday BP, Jones DA, Wage R, Newsome S, Gatehouse P, Firmin D, Jabbour A, Assomull RG, Mathur A, Pennell DJ, Arai AE, Prasad SK.

JACC Cardiovasc Imaging. 2019 Jan 9. pii: S1936-878X(18)31093-3. doi: 10.1016/j.jcmg.2018.10.032. [Epub ahead of print]


Prediction and prevention of heart failure in high-risk elderly patients.

Halliday BP, Pennell DJ.

Eur Heart J. 2019 Feb 7;40(6):539-541. doi: 10.1093/eurheartj/ehy876. No abstract available.


Withdrawal of pharmacological treatment for heart failure in patients with recovered dilated cardiomyopathy (TRED-HF): an open-label, pilot, randomised trial.

Halliday BP, Wassall R, Lota AS, Khalique Z, Gregson J, Newsome S, Jackson R, Rahneva T, Wage R, Smith G, Venneri L, Tayal U, Auger D, Midwinter W, Whiffin N, Rajani R, Dungu JN, Pantazis A, Cook SA, Ware JS, Baksi AJ, Pennell DJ, Rosen SD, Cowie MR, Cleland JGF, Prasad SK.

Lancet. 2019 Jan 5;393(10166):61-73. doi: 10.1016/S0140-6736(18)32484-X. Epub 2018 Nov 11.


High resolution in-vivo DT-CMR using an interleaved variable density spiral STEAM sequence.

Gorodezky M, Ferreira PF, Nielles-Vallespin S, Gatehouse PD, Pennell DJ, Scott AD, Firmin DN.

Magn Reson Med. 2019 Mar;81(3):1580-1594. doi: 10.1002/mrm.27504. Epub 2018 Nov 8.


Absence of Myocardial Fibrosis Predicts Favorable Long-Term Survival in New-Onset Heart Failure.

Gulati A, Japp AG, Raza S, Halliday BP, Jones DA, Newsome S, Ismail NA, Morarji K, Khwaja J, Spath N, Shakespeare C, Kalra PR, Lloyd G, Mathur A, Cleland JGF, Cowie MR, Assomull RG, Pennell DJ, Ismail TF, Prasad SK.

Circ Cardiovasc Imaging. 2018 Sep;11(9):e007722. doi: 10.1161/CIRCIMAGING.118.007722.


Osteoprotegerin and Myocardial Fibrosis in Patients with Aortic Stenosis.

Loudon BL, Ntatsaki E, Newsome S, Halliday B, Lota A, Ali A, Malley T, Selvendran S, Aggarwal N, Lam W, Donovan J, Auger D, Raphael CE, Flynn PD, Pennell DJ, Vassiliou VS, Prasad SK.

Sci Rep. 2018 Sep 28;8(1):14550. doi: 10.1038/s41598-018-32738-y.


Outcome in Dilated Cardiomyopathy Related to the Extent, Location, and Pattern of Late Gadolinium Enhancement.

Halliday BP, Baksi AJ, Gulati A, Ali A, Newsome S, Izgi C, Arzanauskaite M, Lota A, Tayal U, Vassiliou VS, Gregson J, Alpendurada F, Frenneaux MP, Cook SA, Cleland JGF, Pennell DJ, Prasad SK.

JACC Cardiovasc Imaging. 2018 Sep 6. pii: S1936-878X(18)30670-3. doi: 10.1016/j.jcmg.2018.07.015. [Epub ahead of print]


Ramipril and left ventricular diastolic function in stable patients with pulmonary regurgitation after repair of tetralogy of Fallot.

Krupickova S, Li W, Cheang MH, Rigby ML, Uebing A, Davlouros P, Dimopoulos K, Di Salvo G, Fraisse A, Swan L, Alonso-Gonzalez R, Kempny A, Pennell DJ, Senior R, Gatzoulis MA, Babu-Narayan SV.

Int J Cardiol. 2018 Dec 1;272:64-69. doi: 10.1016/j.ijcard.2018.07.132. Epub 2018 Aug 1.


Sex- and age-based differences in the natural history and outcome of dilated cardiomyopathy.

Halliday BP, Gulati A, Ali A, Newsome S, Lota A, Tayal U, Vassiliou VS, Arzanauskaite M, Izgi C, Krishnathasan K, Singhal A, Chiew K, Gregson J, Frenneaux MP, Cook SA, Pennell DJ, Collins P, Cleland JGF, Prasad SK.

Eur J Heart Fail. 2018 Oct;20(10):1392-1400. doi: 10.1002/ejhf.1216. Epub 2018 Jun 3.


Diffusion Tensor Cardiovascular Magnetic Resonance of Microstructural Recovery in Dilated Cardiomyopathy.

Khalique Z, Ferreira PF, Scott AD, Nielles-Vallespin S, Wage R, Firmin DN, Pennell DJ.

JACC Cardiovasc Imaging. 2018 Oct;11(10):1548-1550. doi: 10.1016/j.jcmg.2018.01.025. Epub 2018 Mar 14. No abstract available.


What is CMR doing for patients today?

Khalique Z, Pennell DJ.

Eur Heart J. 2018 Jan 21;39(4):266-270. doi: 10.1093/eurheartj/ehx778. No abstract available.


Deranged Myocyte Microstructure in Situs Inversus Totalis Demonstrated by Diffusion Tensor Cardiac Magnetic Resonance.

Khalique Z, Ferreira PF, Scott AD, Nielles-Vallespin S, Kilner PJ, Kutys R, Romero M, Arai AE, Firmin DN, Pennell DJ.

JACC Cardiovasc Imaging. 2018 Sep;11(9):1360-1362. doi: 10.1016/j.jcmg.2017.11.014. Epub 2018 Jan 17. No abstract available.


An in-vivo comparison of stimulated-echo and motion compensated spin-echo sequences for 3 T diffusion tensor cardiovascular magnetic resonance at multiple cardiac phases.

Scott AD, Nielles-Vallespin S, Ferreira PF, Khalique Z, Gatehouse PD, Kilner P, Pennell DJ, Firmin DN.

J Cardiovasc Magn Reson. 2018 Jan 3;20(1):1. doi: 10.1186/s12968-017-0425-8.


Diffusion tensor cardiovascular magnetic resonance with a spiral trajectory: An in vivo comparison of echo planar and spiral stimulated echo sequences.

Gorodezky M, Scott AD, Ferreira PF, Nielles-Vallespin S, Pennell DJ, Firmin DN.

Magn Reson Med. 2018 Aug;80(2):648-654. doi: 10.1002/mrm.27051. Epub 2017 Dec 19.


Immediate and Midterm Cardiac Remodeling After Surgical Pulmonary Valve Replacement in Adults With Repaired Tetralogy of Fallot: A Prospective Cardiovascular Magnetic Resonance and Clinical Study.

Heng EL, Gatzoulis MA, Uebing A, Sethia B, Uemura H, Smith GC, Diller GP, McCarthy KP, Ho SY, Li W, Wright P, Spadotto V, Kilner PJ, Oldershaw P, Pennell DJ, Shore DF, Babu-Narayan SV.

Circulation. 2017 Oct 31;136(18):1703-1713. doi: 10.1161/CIRCULATIONAHA.117.027402.


Response to: Ultrasonographic assessment of tonsillar volume in children.

Asimakopoulos P, Pennell DJL, Mamais C, Veitch D, Stafrace S, Engelhardt T.

Int J Pediatr Otorhinolaryngol. 2017 Oct;101:261. doi: 10.1016/j.ijporl.2017.08.002. Epub 2017 Aug 4. No abstract available.


Effect of Pregnancy on Ventricular and Aortic Dimensions in Repaired Tetralogy of Fallot.

Cauldwell M, Quail MA, Smith GS, Heng EL, Ghonim S, Uebing A, Swan L, Li W, Patel RR, Pennell DJ, Steer PJ, Johnson MR, Gatzoulis MA, Babu-Narayan SV.

J Am Heart Assoc. 2017 Jul 23;6(7). pii: e005420. doi: 10.1161/JAHA.116.005420.


Evaluation of the impact of strain correction on the orientation of cardiac diffusion tensors with in vivo and ex vivo porcine hearts.

Ferreira PF, Nielles-Vallespin S, Scott AD, de Silva R, Kilner PJ, Ennis DB, Auger DA, Suever JD, Zhong X, Spottiswoode BS, Pennell DJ, Arai AE, Firmin DN.

Magn Reson Med. 2018 Apr;79(4):2205-2215. doi: 10.1002/mrm.26850. Epub 2017 Jul 21.


Lipoprotein(a) in patients with aortic stenosis: Insights from cardiovascular magnetic resonance.

Vassiliou VS, Flynn PD, Raphael CE, Newsome S, Khan T, Ali A, Halliday B, Studer Bruengger A, Malley T, Sharma P, Selvendran S, Aggarwal N, Sri A, Berry H, Donovan J, Lam W, Auger D, Cook SA, Pennell DJ, Prasad SK.

PLoS One. 2017 Jul 13;12(7):e0181077. doi: 10.1371/journal.pone.0181077. eCollection 2017.


Major adverse events and atrial tachycardia in Ebstein's anomaly predicted by cardiovascular magnetic resonance.

Rydman R, Shiina Y, Diller GP, Niwa K, Li W, Uemura H, Uebing A, Barbero U, Bouzas B, Ernst S, Wong T, Pennell DJ, Gatzoulis MA, Babu-Narayan SV.

Heart. 2018 Jan;104(1):37-44. doi: 10.1136/heartjnl-2017-311274. Epub 2017 Jul 6.


A feasibility and safety study of intracoronary hemodilution during primary coronary angioplasty in order to reduce reperfusion injury in myocardial infarction.

McGarvey M, Ali O, Iqbal MB, Ilsley C, Wong J, Di Mario C, Redwood S, Patterson T, Pennell DJ, Rogers P, Dalby M; ORCA-3 For the Optimal Restoration of Cardiac Activity (ORCA) Group.

Catheter Cardiovasc Interv. 2018 Feb 1;91(2):234-241. doi: 10.1002/ccd.27136. Epub 2017 Jun 21.


Identification of myocardial diffuse fibrosis by 11 heartbeat MOLLI T 1 mapping: averaging to improve precision and correlation with collagen volume fraction.

Vassiliou VS, Wassilew K, Cameron D, Heng EL, Nyktari E, Asimakopoulos G, de Souza A, Giri S, Pierce I, Jabbour A, Firmin D, Frenneaux M, Gatehouse P, Pennell DJ, Prasad SK.

MAGMA. 2018 Feb;31(1):101-113. doi: 10.1007/s10334-017-0630-3. Epub 2017 Jun 12.


Ultrasonographic assessment of tonsillar volume in children.

Asimakopoulos P, Pennell DJL, Mamais C, Veitch D, Stafrace S, Engelhardt T.

Int J Pediatr Otorhinolaryngol. 2017 Apr;95:1-4. doi: 10.1016/j.ijporl.2017.01.024. Epub 2017 Jan 24.


Late Anthracycline-Related Cardiotoxicity in Low-Risk Breast Cancer Patients.

Maestrini V, Cheang MH, Kotwinski P, Rosmini S, Lloyd G, Kellman P, Pennell DJ, Montgomery H, Moon JC, Manisty C.

J Am Coll Cardiol. 2017 May 23;69(20):2573-2575. doi: 10.1016/j.jacc.2017.03.560. No abstract available.


Apheresis as novel treatment for refractory angina with raised lipoprotein(a): a randomized controlled cross-over trial.

Khan TZ, Hsu LY, Arai AE, Rhodes S, Pottle A, Wage R, Banya W, Gatehouse PD, Giri S, Collins P, Pennell DJ, Barbir M.

Eur Heart J. 2017 May 21;38(20):1561-1569. doi: 10.1093/eurheartj/ehx178.


Aortic Dilatation in Repaired Tetralogy of Fallot.

Bonello B, Shore DF, Uebing A, Diller GP, Keegan J, Burman ED, Shiina Y, Swan L, Pennell DJ, Kilner PJ, Beurtheret S, Gatzoulis MA, Babu-Narayan SV.

JACC Cardiovasc Imaging. 2018 Jan;11(1):150-152. doi: 10.1016/j.jcmg.2017.01.021. Epub 2017 Apr 12. No abstract available.


Midwall Fibrosis and 5-Year Outcome in Moderate and Severe Aortic Stenosis.

Vassiliou VS, Perperoglou A, Raphael CE, Joshi S, Malley T, Everett R, Halliday B, Pennell DJ, Dweck MR, Prasad SK.

J Am Coll Cardiol. 2017 Apr 4;69(13):1755-1756. doi: 10.1016/j.jacc.2017.01.034. No abstract available.


Association Between Midwall Late Gadolinium Enhancement and Sudden Cardiac Death in Patients With Dilated Cardiomyopathy and Mild and Moderate Left Ventricular Systolic Dysfunction.

Halliday BP, Gulati A, Ali A, Guha K, Newsome S, Arzanauskaite M, Vassiliou VS, Lota A, Izgi C, Tayal U, Khalique Z, Stirrat C, Auger D, Pareek N, Ismail TF, Rosen SD, Vazir A, Alpendurada F, Gregson J, Frenneaux MP, Cowie MR, Cleland JGF, Cook SA, Pennell DJ, Prasad SK.

Circulation. 2017 May 30;135(22):2106-2115. doi: 10.1161/CIRCULATIONAHA.116.026910. Epub 2017 Mar 28.


Post-mortem study of the association between cardiac iron and fibrosis in transfusion dependent anaemia.

Kirk P, Sheppard M, Carpenter JP, Anderson L, He T, St Pierre T, Galanello R, Catani G, Wood J, Fucharoen S, Porter JB, Walker JM, Forni GL, Pennell DJ.

J Cardiovasc Magn Reson. 2017 Mar 27;19(1):36. doi: 10.1186/s12968-017-0349-3.


Evaluation of cardiac and hepatic iron overload in thalassemia major patients with T2* magnetic resonance imaging.

Wahidiyat PA, Liauw F, Sekarsari D, Putriasih SA, Berdoukas V, Pennell DJ.

Hematology. 2017 Sep;22(8):501-507. doi: 10.1080/10245332.2017.1292614. Epub 2017 Feb 20.


Anomalous drainage of isolated superior caval vein to the left atrium: the oldest reported unrepaired case.

Boutsikou M, Pennell DJ, Nyktari E.

Cardiol Young. 2017 Jul;27(5):1008-1010. doi: 10.1017/S1047951116002808. Epub 2017 Feb 15.


Assessment of Myocardial Microstructural Dynamics by In Vivo Diffusion Tensor Cardiac Magnetic Resonance.

Nielles-Vallespin S, Khalique Z, Ferreira PF, de Silva R, Scott AD, Kilner P, McGill LA, Giannakidis A, Gatehouse PD, Ennis D, Aliotta E, Al-Khalil M, Kellman P, Mazilu D, Balaban RS, Firmin DN, Arai AE, Pennell DJ.

J Am Coll Cardiol. 2017 Feb 14;69(6):661-676. doi: 10.1016/j.jacc.2016.11.051.


Feasibility of cardiovascular magnetic resonance derived coronary wave intensity analysis.

Raphael CE, Keegan J, Parker KH, Simpson R, Collinson J, Vassiliou V, Wage R, Drivas P, Strain S, Cooper R, de Silva R, Stables RH, Di Mario C, Frenneaux M, Pennell DJ, Davies JE, Hughes AD, Firmin D, Prasad SK.

J Cardiovasc Magn Reson. 2016 Dec 9;18(1):93.


Body Surface Area and Baseline Blood Pressure Predict Subclinical Anthracycline Cardiotoxicity in Women Treated for Early Breast Cancer.

Kotwinski P, Smith G, Cooper J, Sanders J, Ma L, Teis A, Kotwinski D, Mythen M, Pennell DJ, Jones A, Montgomery H; Breast cancer Early disease: Toxicity from Therapy with Epirubicin Regimens–Cardiac Assessment and Risk Evaluation (BETTER-CARE) Study Investigators.

PLoS One. 2016 Dec 2;11(12):e0165262. doi: 10.1371/journal.pone.0165262. eCollection 2016.


Review of Journal of Cardiovascular Magnetic Resonance 2015.

Pennell DJ, Baksi AJ, Prasad SK, Mohiaddin RH, Alpendurada F, Babu-Narayan SV, Schneider JE, Firmin DN.

J Cardiovasc Magn Reson. 2016 Nov 15;18(1):86. Review.


Characterization of left and right atrial function in healthy volunteers by cardiovascular magnetic resonance.

Maceira AM, Cosin-Sales J, Prasad SK, Pennell DJ.

J Cardiovasc Magn Reson. 2016 Oct 10;18(1):64.


Mechanisms of Myocardial Ischemia in Hypertrophic Cardiomyopathy: Insights From Wave Intensity Analysis and Magnetic Resonance.

Raphael CE, Cooper R, Parker KH, Collinson J, Vassiliou V, Pennell DJ, de Silva R, Hsu LY, Greve AM, Nijjer S, Broyd C, Ali A, Keegan J, Francis DP, Davies JE, Hughes AD, Arai A, Frenneaux M, Stables RH, Di Mario C, Prasad SK.

J Am Coll Cardiol. 2016 Oct 11;68(15):1651-1660. doi: 10.1016/j.jacc.2016.07.751.


Magnetic resonance imaging phantoms for quality-control of myocardial T1 and ECV mapping: specific formulation, long-term stability and variation with heart rate and temperature.

Vassiliou VS, Heng EL, Gatehouse PD, Donovan J, Raphael CE, Giri S, Babu-Narayan SV, Gatzoulis MA, Pennell DJ, Prasad SK, Firmin DN.

J Cardiovasc Magn Reson. 2016 Sep 22;18(1):62.


Prevalence and Prognostic Significance of Right Ventricular Systolic Dysfunction in Patients Undergoing Transcatheter Aortic Valve Implantation.

Lindsay AC, Harron K, Jabbour RJ, Kanyal R, Snow TM, Sawhney P, Alpendurada F, Roughton M, Pennell DJ, Duncan A, Di Mario C, Davies SW, Mohiaddin RH, Moat NE.

Circ Cardiovasc Interv. 2016 Jul;9(7). pii: e003486. doi: 10.1161/CIRCINTERVENTIONS.115.003486.


Comparison of 3 T and 1.5 T for T2* magnetic resonance of tissue iron.

Alam MH, Auger D, McGill LA, Smith GC, He T, Izgi C, Baksi AJ, Wage R, Drivas P, Firmin DN, Pennell DJ.

J Cardiovasc Magn Reson. 2016 Jul 8;18(1):40. doi: 10.1186/s12968-016-0259-9.


Burden of Cardiac Siderosis in a Thalassemia-Major Endemic Population: A Preliminary Report From Pakistan.

Alvi N, Tipoo FA, Imran A, Ashraf MN, Qidwai A, Khursheed M, Moiz B, Adil SN, Fadoo Z, Altaf S, Pennell DJ, Hasan BS.

J Pediatr Hematol Oncol. 2016 Jul;38(5):378-83. doi: 10.1097/MPH.0000000000000574.


Validation of T2* in-line analysis for tissue iron quantification at 1.5 T.

Alam MH, He T, Auger D, Smith GC, Drivas P, Wage R, Izgi C, Symmonds K, Greiser A, Spottiswoode BS, Anderson L, Firmin D, Pennell DJ.

J Cardiovasc Magn Reson. 2016 Apr 27;18(1):23. doi: 10.1186/s12968-016-0243-4.


Value of Formalin Fixation for the Prolonged Preservation of Rodent Myocardial Microanatomical Organization: Evidence by MR Diffusion Tensor Imaging.

Giannakidis A, Gullberg GT, Pennell DJ, Firmin DN.

Anat Rec (Hoboken). 2016 Jul;299(7):878-87. doi: 10.1002/ar.23359. Epub 2016 May 10.


CMR Guidance for Recanalization of Coronary Chronic Total Occlusion.

Bucciarelli-Ducci C, Auger D, Di Mario C, Locca D, Petryka J, O'Hanlon R, Grasso A, Wright C, Symmonds K, Wage R, Asimacopoulos E, Del Furia F, Lyne JC, Gatehouse PD, Fox KM, Pennell DJ.

JACC Cardiovasc Imaging. 2016 May;9(5):547-56. doi: 10.1016/j.jcmg.2015.10.025. Epub 2016 Apr 13.


Renal denervation in heart failure with preserved ejection fraction (RDT-PEF): a randomized controlled trial.

Patel HC, Rosen SD, Hayward C, Vassiliou V, Smith GC, Wage RR, Bailey J, Rajani R, Lindsay AC, Pennell DJ, Underwood SR, Prasad SK, Mohiaddin R, Gibbs JS, Lyon AR, Di Mario C.

Eur J Heart Fail. 2016 Jun;18(6):703-12. doi: 10.1002/ejhf.502. Epub 2016 Mar 16.


Cardiac complications in thalassemia major.

Auger D, Pennell DJ.

Ann N Y Acad Sci. 2016 Mar;1368(1):56-64. doi: 10.1111/nyas.13026. Epub 2016 Mar 9. Review.


Left atrial dilation in patients with heart failure and preserved ejection fraction: Insights from cardiovascular magnetic resonance.

Vassiliou VS, Patel HC, Rosen SD, Auger D, Hayward C, Alpendurada F, Lyon AR, Pennell DJ, Di Mario C, Prasad SK.

Int J Cardiol. 2016 May 1;210:158-60. doi: 10.1016/j.ijcard.2016.02.101. Epub 2016 Feb 21. No abstract available.

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