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Items: 1 to 50 of 76

1.

Shared and distinct transcriptomic cell types across neocortical areas.

Tasic B, Yao Z, Graybuck LT, Smith KA, Nguyen TN, Bertagnolli D, Goldy J, Garren E, Economo MN, Viswanathan S, Penn O, Bakken T, Menon V, Miller J, Fong O, Hirokawa KE, Lathia K, Rimorin C, Tieu M, Larsen R, Casper T, Barkan E, Kroll M, Parry S, Shapovalova NV, Hirschstein D, Pendergraft J, Sullivan HA, Kim TK, Szafer A, Dee N, Groblewski P, Wickersham I, Cetin A, Harris JA, Levi BP, Sunkin SM, Madisen L, Daigle TL, Looger L, Bernard A, Phillips J, Lein E, Hawrylycz M, Svoboda K, Jones AR, Koch C, Zeng H.

Nature. 2018 Nov;563(7729):72-78. doi: 10.1038/s41586-018-0654-5. Epub 2018 Oct 31.

2.

Corrigendum: Independent Evolution of Strychnine Recognition by Bitter Taste Receptor Subtypes.

Xue AY, Di Pizio A, Levit A, Yarnitzky T, Penn O, Pupko T, Niv MY.

Front Mol Biosci. 2018 Sep 11;5:84. doi: 10.3389/fmolb.2018.00084. eCollection 2018.

3.

Transcriptional fates of human-specific segmental duplications in brain.

Dougherty ML, Underwood JG, Nelson BJ, Tseng E, Munson KM, Penn O, Nowakowski TJ, Pollen AA, Eichler EE.

Genome Res. 2018 Oct;28(10):1566-1576. doi: 10.1101/gr.237610.118. Epub 2018 Sep 18.

4.

Independent Evolution of Strychnine Recognition by Bitter Taste Receptor Subtypes.

Xue AY, Di Pizio A, Levit A, Yarnitzky T, Penn O, Pupko T, Niv MY.

Front Mol Biosci. 2018 Mar 2;5:9. doi: 10.3389/fmolb.2018.00009. eCollection 2018. Erratum in: Front Mol Biosci. 2018 Sep 11;5:84.

5.

The evolution and population diversity of human-specific segmental duplications.

Dennis MY, Harshman L, Nelson BJ, Penn O, Cantsilieris S, Huddleston J, Antonacci F, Penewit K, Denman L, Raja A, Baker C, Mark K, Malig M, Janke N, Espinoza C, Stessman HAF, Nuttle X, Hoekzema K, Lindsay-Graves TA, Wilson RK, Eichler EE.

Nat Ecol Evol. 2017;1(3):69. doi: 10.1038/s41559-016-0069. Epub 2017 Feb 17.

6.

The birth of a human-specific neural gene by incomplete duplication and gene fusion.

Dougherty ML, Nuttle X, Penn O, Nelson BJ, Huddleston J, Baker C, Harshman L, Duyzend MH, Ventura M, Antonacci F, Sandstrom R, Dennis MY, Eichler EE.

Genome Biol. 2017 Mar 9;18(1):49. doi: 10.1186/s13059-017-1163-9.

7.

Emergence of a Homo sapiens-specific gene family and chromosome 16p11.2 CNV susceptibility.

Nuttle X, Giannuzzi G, Duyzend MH, Schraiber JG, Narvaiza I, Sudmant PH, Penn O, Chiatante G, Malig M, Huddleston J, Benner C, Camponeschi F, Ciofi-Baffoni S, Stessman HA, Marchetto MC, Denman L, Harshman L, Baker C, Raja A, Penewit K, Janke N, Tang WJ, Ventura M, Banci L, Antonacci F, Akey JM, Amemiya CT, Gage FH, Reymond A, Eichler EE.

Nature. 2016 Aug 11;536(7615):205-9. Epub 2016 Aug 3.

8.

Disruption of POGZ Is Associated with Intellectual Disability and Autism Spectrum Disorders.

Stessman HAF, Willemsen MH, Fenckova M, Penn O, Hoischen A, Xiong B, Wang T, Hoekzema K, Vives L, Vogel I, Brunner HG, van der Burgt I, Ockeloen CW, Schuurs-Hoeijmakers JH, Klein Wassink-Ruiter JS, Stumpel C, Stevens SJC, Vles HS, Marcelis CM, van Bokhoven H, Cantagrel V, Colleaux L, Nicouleau M, Lyonnet S, Bernier RA, Gerdts J, Coe BP, Romano C, Alberti A, Grillo L, Scuderi C, Nordenskjöld M, Kvarnung M, Guo H, Xia K, Piton A, Gerard B, Genevieve D, Delobel B, Lehalle D, Perrin L, Prieur F, Thevenon J, Gecz J, Shaw M, Pfundt R, Keren B, Jacquette A, Schenck A, Eichler EE, Kleefstra T.

Am J Hum Genet. 2016 Mar 3;98(3):541-552. doi: 10.1016/j.ajhg.2016.02.004.

9.

Assessing the prediction fidelity of ancestral reconstruction by a library approach.

Bar-Rogovsky H, Stern A, Penn O, Kobl I, Pupko T, Tawfik DS.

Protein Eng Des Sel. 2015 Nov;28(11):507-18. doi: 10.1093/protein/gzv038. Epub 2015 Aug 13.

PMID:
26275856
10.

The discovery of integrated gene networks for autism and related disorders.

Hormozdiari F, Penn O, Borenstein E, Eichler EE.

Genome Res. 2015 Jan;25(1):142-54. doi: 10.1101/gr.178855.114. Epub 2014 Nov 5.

11.

Disruptive CHD8 mutations define a subtype of autism early in development.

Bernier R, Golzio C, Xiong B, Stessman HA, Coe BP, Penn O, Witherspoon K, Gerdts J, Baker C, Vulto-van Silfhout AT, Schuurs-Hoeijmakers JH, Fichera M, Bosco P, Buono S, Alberti A, Failla P, Peeters H, Steyaert J, Vissers LELM, Francescatto L, Mefford HC, Rosenfeld JA, Bakken T, O'Roak BJ, Pawlus M, Moon R, Shendure J, Amaral DG, Lein E, Rankin J, Romano C, de Vries BBA, Katsanis N, Eichler EE.

Cell. 2014 Jul 17;158(2):263-276. doi: 10.1016/j.cell.2014.06.017. Epub 2014 Jul 3.

12.

Deep Panning: steps towards probing the IgOme.

Ryvkin A, Ashkenazy H, Smelyanski L, Kaplan G, Penn O, Weiss-Ottolenghi Y, Privman E, Ngam PB, Woodward JE, May GD, Bell C, Pupko T, Gershoni JM.

PLoS One. 2012;7(8):e41469. doi: 10.1371/journal.pone.0041469. Epub 2012 Aug 1.

13.

FastML: a web server for probabilistic reconstruction of ancestral sequences.

Ashkenazy H, Penn O, Doron-Faigenboim A, Cohen O, Cannarozzi G, Zomer O, Pupko T.

Nucleic Acids Res. 2012 Jul;40(Web Server issue):W580-4. doi: 10.1093/nar/gks498. Epub 2012 May 31.

14.

Emergence of an HIV-1 cluster harbouring the major protease L90M mutation among treatment-naïve patients in Tel Aviv, Israel.

Turner D, Amit S, Chalom S, Penn O, Pupko T, Katchman E, Matus N, Tellio H, Katzir M, Avidor B.

HIV Med. 2012 Apr;13(4):202-6. doi: 10.1111/j.1468-1293.2011.00960.x. Epub 2011 Nov 3.

15.

Changes in exon-intron structure during vertebrate evolution affect the splicing pattern of exons.

Gelfman S, Burstein D, Penn O, Savchenko A, Amit M, Schwartz S, Pupko T, Ast G.

Genome Res. 2012 Jan;22(1):35-50. doi: 10.1101/gr.119834.110. Epub 2011 Oct 5.

16.

Improving the performance of positive selection inference by filtering unreliable alignment regions.

Privman E, Penn O, Pupko T.

Mol Biol Evol. 2012 Jan;29(1):1-5. doi: 10.1093/molbev/msr177. Epub 2011 Jul 19.

PMID:
21772063
17.

Preoperative prediction of early mortality in patients with low ejection fraction undergoing coronary artery bypass grafting.

Soliman Hamad MA, van Straten AH, van Zundert AA, ter Woorst JF, Martens EJ, Penn OC.

J Card Surg. 2011 Jan;26(1):9-15. doi: 10.1111/j.1540-8191.2010.01161.x. Epub 2010 Nov 14.

PMID:
21073534
18.

An evolutionary analysis of lateral gene transfer in thymidylate synthase enzymes.

Stern A, Mayrose I, Penn O, Shaul S, Gophna U, Pupko T.

Syst Biol. 2010 Mar;59(2):212-25. doi: 10.1093/sysbio/syp104. Epub 2010 Jan 15.

19.

GUIDANCE: a web server for assessing alignment confidence scores.

Penn O, Privman E, Ashkenazy H, Landan G, Graur D, Pupko T.

Nucleic Acids Res. 2010 Jul;38(Web Server issue):W23-8. doi: 10.1093/nar/gkq443. Epub 2010 May 23.

20.

An alignment confidence score capturing robustness to guide tree uncertainty.

Penn O, Privman E, Landan G, Graur D, Pupko T.

Mol Biol Evol. 2010 Aug;27(8):1759-67. doi: 10.1093/molbev/msq066. Epub 2010 Mar 5.

21.

Rodent phylogeny revised: analysis of six nuclear genes from all major rodent clades.

Blanga-Kanfi S, Miranda H, Penn O, Pupko T, DeBry RW, Huchon D.

BMC Evol Biol. 2009 Apr 2;9:71. doi: 10.1186/1471-2148-9-71.

22.

Evolutionary modeling of rate shifts reveals specificity determinants in HIV-1 subtypes.

Penn O, Stern A, Rubinstein ND, Dutheil J, Bacharach E, Galtier N, Pupko T.

PLoS Comput Biol. 2008 Nov;4(11):e1000214. doi: 10.1371/journal.pcbi.1000214. Epub 2008 Nov 7.

23.

Pepitope: epitope mapping from affinity-selected peptides.

Mayrose I, Penn O, Erez E, Rubinstein ND, Shlomi T, Freund NT, Bublil EM, Ruppin E, Sharan R, Gershoni JM, Martz E, Pupko T.

Bioinformatics. 2007 Dec 1;23(23):3244-6. Epub 2007 Oct 31.

PMID:
17977889
24.

Does stenosis severity of native vessels influence bypass graft patency? A prospective fractional flow reserve-guided study.

Botman CJ, Schonberger J, Koolen S, Penn O, Botman H, Dib N, Eeckhout E, Pijls N.

Ann Thorac Surg. 2007 Jun;83(6):2093-7.

PMID:
17532405
25.

Stepwise prediction of conformational discontinuous B-cell epitopes using the Mapitope algorithm.

Bublil EM, Freund NT, Mayrose I, Penn O, Roitburd-Berman A, Rubinstein ND, Pupko T, Gershoni JM.

Proteins. 2007 Jul 1;68(1):294-304.

PMID:
17427229
27.

Long-term outcome after surgical left main coronary angioplasty.

Botman CJ, Arnoudse W, Penn O, Pijls N.

Ann Thorac Surg. 2006 Mar;81(3):828-34.

PMID:
16488680
28.

Percutaneous coronary intervention or bypass surgery in multivessel disease? A tailored approach based on coronary pressure measurement.

Botman KJ, Pijls NH, Bech JW, Aarnoudse W, Peels K, van Straten B, Penn O, Michels HR, Bonnier H, Koolen JJ.

Catheter Cardiovasc Interv. 2004 Oct;63(2):184-91.

PMID:
15390344
29.

Primary malignant peripheral nerve sheath tumour of the heart.

Pauwels P, Dal Cin P, Sciot R, Lammens M, Penn O, van Nes E, Kwee WS, van den Berghe H.

Histopathology. 1999 Jan;34(1):56-9.

PMID:
9934585
30.

Combined approach to stent-graft treatment of an aortic arch aneurysm.

Buth J, Penn O, Tielbeek A, Mersman M.

J Endovasc Surg. 1998 Nov;5(4):329-32.

PMID:
9867322
31.

Acquired ventricular septal defect and mitral insufficiency without pericardial effusion after stab wound to the chest.

Pasteuning WH, Wonnink-de Jonge WF, van Berge Henegouwen DP, van der Aa MA, Penn OC.

J Am Soc Echocardiogr. 1998 May;11(5):483-6.

PMID:
9619622
32.

Structural alterations in the latissimus dorsi muscles in three patients more than 2 years after a cardiomyoplasty procedure.

Davidse JH, van der Veen FH, Lucas CM, Penn OC, Daemen MJ, Wellens HJ.

Eur Heart J. 1998 Feb;19(2):310-8.

PMID:
9519326
33.

Configuration of unipolar atrial electrograms during electrically induced atrial fibrillation in humans.

Konings KT, Smeets JL, Penn OC, Wellens HJ, Allessie MA.

Circulation. 1997 Mar 4;95(5):1231-41.

PMID:
9054854
34.

Single injection thermodilution. A flow-corrected method.

Jansen JR, Schreuder JJ, Settels JJ, Kornet L, Penn OC, Mulder PG, Versprille A, Wesseling KH.

Anesthesiology. 1996 Sep;85(3):481-90.

PMID:
8853077
35.

Automated infusion of nitroglycerin to control arterial hypertension during cardiac surgery.

Hoeksel SA, Schreuder JJ, Blom JA, Maessen JG, Penn OC.

Intensive Care Med. 1996 Jul;22(7):688-93.

PMID:
8844236
36.

Influence of Duraflo II heparin-treated extracorporeal circuits on the systemic inflammatory response in patients having coronary bypass.

Weerwind PW, Maessen JG, van Tits LJ, Stad RK, Fransen EJ, de Jong DS, Penn OC.

J Thorac Cardiovasc Surg. 1995 Dec;110(6):1633-41.

37.

High-density mapping of electrically induced atrial fibrillation in humans.

Konings KT, Kirchhof CJ, Smeets JR, Wellens HJ, Penn OC, Allessie MA.

Circulation. 1994 Apr;89(4):1665-80.

PMID:
8149534
38.

The 12-lead electrocardiogram in midseptal, anteroseptal, posteroseptal and right free wall accessory pathways.

Rodriguez LM, Smeets JL, de Chillou C, Metzger J, Schläpfer J, Penn O, Weide A, Wellens HJ.

Am J Cardiol. 1993 Dec 1;72(17):1274-80.

PMID:
8256703
39.

A new stimulation protocol for cardiac assist using the latissimus dorsi muscle.

Lucas CM, Dubelaar ML, Van der Veen FH, Kloosterman-Castro-Ravelo E, Havenith M, Habets J, Van der Nagel T, Penn OC, Wellens HJ.

Pacing Clin Electrophysiol. 1993 Oct;16(10):2012-21.

PMID:
7694248
40.

Long-term follow-up (12 to 35 weeks) after dynamic cardiomyoplasty.

Lucas CM, Van der Veen FH, Cheriex EC, Lorusso R, Havenith M, Penn OC, Wellens HJ.

J Am Coll Cardiol. 1993 Sep;22(3):758-67.

41.

[Double supraventricular tachycardia and its surgical treatment].

Tamás F, Smeets JL, Penn OC, Wellens HJ.

Orv Hetil. 1993 Feb 28;134(9):469-72. Review. Hungarian.

PMID:
8446417
42.

Systemic to pulmonary vascular malformation.

Pouwels HM, Janevski BK, Penn OC, Sie HT, ten Velde GP.

Eur Respir J. 1992 Nov;5(10):1288-91. Review.

PMID:
1486979
43.

The importance of muscle relaxation in dynamic cardiomyoplasty.

Lucas CM, van der Veen FH, Cheriex EC, van Ommen V, Penn OC, Wellens HJ.

Pacing Clin Electrophysiol. 1992 Oct;15(10 Pt 1):1430-6.

PMID:
1383953
44.

[Surgical treatment of ventricular tachycardia in patients with post-infarction aneurysms].

Kochman W, Penn O, Biederman A, Chojnowska L, Kwiatkowska D, Ruzyłło W.

Kardiol Pol. 1992 Sep;37(9):146-50. Polish.

PMID:
1479771
45.

Imipramine induced heart failure in the dog: a model to study the effect of cardiac assist devices.

Lucas CM, Cheriex EC, van der Veen FH, Habets J, van der Nagel T, Penn OC, Wellens HJ.

Cardiovasc Res. 1992 Aug;26(8):804-9.

PMID:
1451156
46.

Color Doppler imaging of the right gastroepiploic artery as an in situ coronary artery bypass graft.

Oei KT, Sie HT, Penn OC, van Engelshoven JM.

Eur J Radiol. 1992 Jul-Aug;15(1):37-9.

PMID:
1396786
47.

Postoperative pulmonary function abnormalities after coronary artery bypass surgery.

van Belle AF, Wesseling GJ, Penn OC, Wouters EF.

Respir Med. 1992 May;86(3):195-9.

PMID:
1620905
48.

Changes in canine latissimus dorsi muscle during 24 wk of continuous electrical stimulation.

Lucas CM, Havenith MG, van der Veen FH, Habets J, van der Nagel T, Schrijvers-Van Schendel JM, Penn OC, Wellens HJ.

J Appl Physiol (1985). 1992 Mar;72(3):828-35.

PMID:
1533212
49.

Adaptation of energy metabolism of canine latissimus dorsi muscle in response to chronic electrical stimulation.

Glatz JF, van der Vusse GJ, Havenith MG, van der Veen FH, Lucas CM, Penn OC, Wellens HJ.

Pflugers Arch. 1992 Jan;420(1):1-8.

PMID:
1553254
50.

What is the ideal pulse frequency for skeletal muscle stimulation after cardiomyoplasty?

Lucas CM, van der Veen FH, Grandjean PA, Penn OC, Wellens HJ.

Pacing Clin Electrophysiol. 1991 May;14(5 Pt 1):778-82.

PMID:
1712953

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