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Items: 26

1.

Matters of life and death: How estrogen and estrogen receptor binding to the immunoglobulin heavy chain locus may influence outcomes of infection, allergy, and autoimmune disease.

Jones BG, Penkert RR, Surman SL, Sealy RE, Pelletier S, Xu B, Neale G, Maul RW, Gearhart PJ, Hurwitz JL.

Cell Immunol. 2019 Dec;346:103996. doi: 10.1016/j.cellimm.2019.103996. Epub 2019 Oct 25. Review.

PMID:
31703914
2.

Baseline Serum Vitamin A and D Levels Determine Benefit of Oral Vitamin A&D Supplements to Humoral Immune Responses Following Pediatric Influenza Vaccination.

Patel N, Penkert RR, Jones BG, Sealy RE, Surman SL, Sun Y, Tang L, DeBeauchamp J, Webb A, Richardson J, Heine R, Dallas RH, Ross AC, Webby R, Hurwitz JL.

Viruses. 2019 Sep 30;11(10). pii: E907. doi: 10.3390/v11100907.

3.

Background check: Profound differences in serum antibody isotypes among C57BL/6 mouse substrains discourage substrain interchanges in immunology experiments.

Jones BG, Penkert RR, Surman SL, Sealy RE, Pelletier S, Berns H, Hurwitz JL.

Immunol Lett. 2019 Dec;216:9-11. doi: 10.1016/j.imlet.2019.05.011. Epub 2019 Aug 19. No abstract available.

PMID:
31437463
4.

Influences of Vitamin A on Vaccine Immunogenicity and Efficacy.

Penkert RR, Rowe HM, Surman SL, Sealy RE, Rosch J, Hurwitz JL.

Front Immunol. 2019 Jul 17;10:1576. doi: 10.3389/fimmu.2019.01576. eCollection 2019.

5.

Will Attention by Vaccine Developers to the Host's Nuclear Hormone Levels and Immunocompetence Improve Vaccine Success?

Sealy RE, Jones BG, Surman SL, Penkert RR, Pelletier S, Neale G, Hurwitz JL.

Vaccines (Basel). 2019 Feb 27;7(1). pii: E26. doi: 10.3390/vaccines7010026. Review.

6.

Complex sex-biased antibody responses: estrogen receptors bind estrogen response elements centered within immunoglobulin heavy chain gene enhancers.

Jones BG, Sealy RE, Penkert RR, Surman SL, Maul RW, Neale G, Xu B, Gearhart PJ, Hurwitz JL.

Int Immunol. 2019 Mar 5;31(3):141-156. doi: 10.1093/intimm/dxy074.

7.

Inflammatory molecule reduction with hydroxyurea therapy in children with sickle cell anemia.

Penkert RR, Hurwitz JL, Thomas P, Rosch J, Dowdy J, Sun Y, Tang L, Hankins JS.

Haematologica. 2018 Feb;103(2):e50-e54. doi: 10.3324/haematol.2017.177360. Epub 2017 Nov 16. No abstract available.

8.

Prevnar-13 vaccine failure in a mouse model for vitamin A deficiency.

Penkert RR, Iverson A, Rosch JW, Hurwitz JL.

Vaccine. 2017 Nov 1;35(46):6264-6268. doi: 10.1016/j.vaccine.2017.09.069. Epub 2017 Oct 9.

9.

Low Retinol-Binding Protein and Vitamin D Levels Are Associated with Severe Outcomes in Children Hospitalized with Lower Respiratory Tract Infection and Respiratory Syncytial Virus or Human Metapneumovirus Detection.

Hurwitz JL, Jones BG, Penkert RR, Gansebom S, Sun Y, Tang L, Bramley AM, Jain S, McCullers JA, Arnold SR.

J Pediatr. 2017 Aug;187:323-327. doi: 10.1016/j.jpeds.2017.04.061. Epub 2017 May 31.

10.

Saccharomyces cerevisiae-derived virus-like particle parvovirus B19 vaccine elicits binding and neutralizing antibodies in a mouse model for sickle cell disease.

Penkert RR, Young NS, Surman SL, Sealy RE, Rosch J, Dormitzer PR, Settembre EC, Chandramouli S, Wong S, Hankins JS, Hurwitz JL.

Vaccine. 2017 Jun 22;35(29):3615-3620. doi: 10.1016/j.vaccine.2017.05.022. Epub 2017 May 26.

11.

Vitamin A differentially regulates cytokine expression in respiratory epithelial and macrophage cell lines.

Penkert RR, Jones BG, H├Ącker H, Partridge JF, Hurwitz JL.

Cytokine. 2017 Mar;91:1-5. doi: 10.1016/j.cyto.2016.11.015. Epub 2016 Dec 8.

12.

Binding of estrogen receptors to switch sites and regulatory elements in the immunoglobulin heavy chain locus of activated B cells suggests a direct influence of estrogen on antibody expression.

Jones BG, Penkert RR, Xu B, Fan Y, Neale G, Gearhart PJ, Hurwitz JL.

Mol Immunol. 2016 Sep;77:97-102. doi: 10.1016/j.molimm.2016.07.015. Epub 2016 Aug 3.

13.

Original Research: Parvovirus B19 infection in children with sickle cell disease in the hydroxyurea era.

Hankins JS, Penkert RR, Lavoie P, Tang L, Sun Y, Hurwitz JL.

Exp Biol Med (Maywood). 2016 Apr;241(7):749-54. doi: 10.1177/1535370216636723. Epub 2016 Mar 2.

14.

Hotspots for Vitamin-Steroid-Thyroid Hormone Response Elements Within Switch Regions of Immunoglobulin Heavy Chain Loci Predict a Direct Influence of Vitamins and Hormones on B Cell Class Switch Recombination.

Hurwitz JL, Penkert RR, Xu B, Fan Y, Partridge JF, Maul RW, Gearhart PJ.

Viral Immunol. 2016 Mar;29(2):132-6. doi: 10.1089/vim.2015.0104. Epub 2016 Jan 7.

15.

Vitamin Supplementation at the Time of Immunization with a Cold-Adapted Influenza Virus Vaccine Corrects Poor Mucosal Antibody Responses in Mice Deficient for Vitamins A and D.

Surman SL, Penkert RR, Jones BG, Sealy RE, Hurwitz JL.

Clin Vaccine Immunol. 2016 Jan 6;23(3):219-27. doi: 10.1128/CVI.00739-15.

16.

Vitamin A deficient mice exhibit increased viral antigens and enhanced cytokine/chemokine production in nasal tissues following respiratory virus infection despite the presence of FoxP3+ T cells.

Penkert RR, Surman SL, Jones BG, Sealy RE, Vogel P, Neale G, Hurwitz JL.

Int Immunol. 2016 Mar;28(3):139-52. doi: 10.1093/intimm/dxv064. Epub 2015 Oct 27.

17.

Heterologous viral promoters incorporated into the human cytomegalovirus genome are silenced during experimental latency.

Qin Q, Penkert RR, Kalejta RF.

J Virol. 2013 Sep;87(17):9886-94. doi: 10.1128/JVI.01726-13. Epub 2013 Jul 3.

18.

Human embryonic stem cell lines model experimental human cytomegalovirus latency.

Penkert RR, Kalejta RF.

mBio. 2013 May 28;4(3):e00298-13. doi: 10.1128/mBio.00298-13.

19.

Tale of a tegument transactivator: the past, present and future of human CMV pp71.

Penkert RR, Kalejta RF.

Future Virol. 2012 Sep 1;7(9):855-869.

20.

Tegument protein control of latent herpesvirus establishment and animation.

Penkert RR, Kalejta RF.

Herpesviridae. 2011 Feb 8;2(1):3. doi: 10.1186/2042-4280-2-3.

21.
22.

Cellular and viral control over the initial events of human cytomegalovirus experimental latency in CD34+ cells.

Saffert RT, Penkert RR, Kalejta RF.

J Virol. 2010 Jun;84(11):5594-604. doi: 10.1128/JVI.00348-10. Epub 2010 Mar 24.

23.

Filament-dependent and -independent localization modes of Drosophila non-muscle myosin II.

Liu SL, Fewkes N, Ricketson D, Penkert RR, Prehoda KE.

J Biol Chem. 2008 Jan 4;283(1):380-7. Epub 2007 Nov 6.

24.

Cdc42 acts downstream of Bazooka to regulate neuroblast polarity through Par-6 aPKC.

Atwood SX, Chabu C, Penkert RR, Doe CQ, Prehoda KE.

J Cell Sci. 2007 Sep 15;120(Pt 18):3200-6. Epub 2007 Aug 28.

25.

Internal recognition through PDZ domain plasticity in the Par-6-Pals1 complex.

Penkert RR, DiVittorio HM, Prehoda KE.

Nat Struct Mol Biol. 2004 Nov;11(11):1122-7. Epub 2004 Oct 10.

26.

Cdc42 regulates the Par-6 PDZ domain through an allosteric CRIB-PDZ transition.

Peterson FC, Penkert RR, Volkman BF, Prehoda KE.

Mol Cell. 2004 Mar 12;13(5):665-76.

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