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An intelligent aerator algorithm inspired-by deep learning.

Deng HJ, Peng LX, Zhang JJ, Tang CM, Fang HL, Liu HH.

Math Biosci Eng. 2019 Apr 10;16(4):2990-3002. doi: 10.3934/mbe.2019148.


GTSE1 is involved in breast cancer progression in p53 mutation-dependent manner.

Lin F, Xie YJ, Zhang XK, Huang TJ, Xu HF, Mei Y, Liang H, Hu H, Lin ST, Luo FF, Lang YH, Peng LX, Qian CN, Huang BJ.

J Exp Clin Cancer Res. 2019 Apr 8;38(1):152. doi: 10.1186/s13046-019-1157-4.


Influence of Calcium Ions on the Thermal Characteristics of α-amylase from Thermophilic Anoxybacillus sp. GXS-BL.

Liao SM, Liang G, Zhu J, Lu B, Peng LX, Wang QY, Wei YT, Zhou GP, Huang RB.

Protein Pept Lett. 2019;26(2):148-157. doi: 10.2174/0929866526666190116162958.


The Inhibition of Polysialyltranseferase ST8SiaIV Through Heparin Binding to Polysialyltransferase Domain (PSTD).

Peng LX, Liu XH, Lu B, Liao SM, Zhou F, Huang JM, Chen D, Troy FA II, Zhou GP, Huang RB.

Med Chem. 2019;15(5):486-495. doi: 10.2174/1573406415666181218101623.


Inhibition of α-amylase Activity by Zn2+: Insights from Spectroscopy and Molecular Dynamics Simulations.

Liao SM, Shen NK, Liang G, Lu B, Lu ZL, Peng LX, Zhou F, Du LQ, Wei YT, Zhou GP, Huang RB.

Med Chem. 2019;15(5):510-520. doi: 10.2174/1573406415666181217114101.


Platycosides P and Q, two new triterpene saponins from Platycodon grandiflorum.

Qiu L, Xiao Y, Liu YQ, Peng LX, Liao W, Fu Q.

J Asian Nat Prod Res. 2019 May;21(5):419-425. doi: 10.1080/10286020.2018.1488835. Epub 2018 Jul 2.


Konjac glucomannan octenyl succinate (KGOS) as an emulsifier for lipophilic bioactive nutrient encapsulation.

Li YC, Zhong G, Meng FB, Yu H, Liu DY, Peng LX.

J Sci Food Agric. 2018 Dec;98(15):5742-5749. doi: 10.1002/jsfa.9122. Epub 2018 Jun 12.


Decreased macrophage inflammatory protein (MIP)-1α and MIP-1β increase the risk of developing nasopharyngeal carcinoma.

Yang MJ, Guo J, Ye YF, Chen SH, Peng LX, Lin CY, Hu T, Xie SH, Xie CB, Huang QH, Lu YQ, Liu Q, Qian CN, Cao SM.

Cancer Commun (Lond). 2018 Apr 3;38(1):7. doi: 10.1186/s40880-018-0279-y.


Global expression profiling and pathway analysis of mouse mammary tumor reveals strain and stage specific dysregulated pathways in breast cancer progression.

Mei Y, Yang JP, Lang YH, Peng LX, Yang MM, Liu Q, Meng DF, Zheng LS, Qiang YY, Xu L, Li CZ, Wei WW, Niu T, Peng XS, Yang Q, Lin F, Hu H, Xu HF, Huang BJ, Wang LJ, Qian CN.

Cell Cycle. 2018;17(8):963-973. doi: 10.1080/15384101.2018.1442629. Epub 2018 May 31.


Along with its favorable prognostic role, CLCA2 inhibits growth and metastasis of nasopharyngeal carcinoma cells via inhibition of FAK/ERK signaling.

Qiang YY, Li CZ, Sun R, Zheng LS, Peng LX, Yang JP, Meng DF, Lang YH, Mei Y, Xie P, Xu L, Cao Y, Wei WW, Cao L, Hu H, Yang Q, Luo DH, Liang YY, Huang BJ, Qian CN.

J Exp Clin Cancer Res. 2018 Feb 20;37(1):34. doi: 10.1186/s13046-018-0692-8.


A comparison of weekly versus 3-weekly cisplatin during concurrent chemoradiotherapy for locoregionally advanced nasopharyngeal carcinoma using intensity modulated radiation therapy: a matched study.

Meng DF, Sun R, Peng LX, Huang YS, Yang Q, Luo DH, Hu WH, Xie FY, Luo W, Zhao C, Guo L, Mai HQ, Chen MY, Xie P, Zheng LS, Yang JP, Mei Y, Qiang YY, Xu L, Li CZ, Huang BJ, Qian CN, Sun R.

J Cancer. 2018 Jan 1;9(1):92-99. doi: 10.7150/jca.21357. eCollection 2018.


The developmental transcription factor IRF6 attenuates ABCG2 gene expression and distinctively reverses stemness phenotype in nasopharyngeal carcinoma.

Xu L, Huang TJ, Hu H, Wang MY, Shi SM, Yang Q, Lin F, Qiang YY, Mei Y, Lang YH, Li CZ, Peng LX, Zheng LS, Huang JL, Li XJ, Zhang SJ, Qian CN, Huang BJ.

Cancer Lett. 2018 Sep 1;431:230-243. doi: 10.1016/j.canlet.2017.10.016. Epub 2017 Oct 27.


Promoting tumorigenesis in nasopharyngeal carcinoma, NEDD8 serves as a potential theranostic target.

Xie P, Yang JP, Cao Y, Peng LX, Zheng LS, Sun R, Meng DF, Wang MY, Mei Y, Qiang YY, Cao L, Xiang YQ, Luo DH, Yun JP, Huang BJ, Jia LJ, Qian CN.

Cell Death Dis. 2017 Jun 1;8(6):e2834. doi: 10.1038/cddis.2017.195.


Erratum to: CDC42-interacting protein 4 promotes metastasis of nasopharyngeal carcinoma by mediating invadopodia formation and activating EGFR signaling.

Meng DF, Xie P, Peng LX, Sun R, Luo DH, Chen QY, Lv X, Wang L, Chen MY, Mai HQ, Guo L, Guo X, Zheng LS, Cao L, Yang JP, Wang MY, Mei Y, Qiang YY, Zhang ZM, Yun JP, Huang BJ, Qian CN.

J Exp Clin Cancer Res. 2017 Feb 20;36(1):33. doi: 10.1186/s13046-017-0503-7. No abstract available.


CDC42-interacting protein 4 promotes metastasis of nasopharyngeal carcinoma by mediating invadopodia formation and activating EGFR signaling.

Meng DF, Xie P, Peng LX, Sun R, Luo DH, Chen QY, Lv X, Wang L, Chen MY, Mai HQ, Guo L, Guo X, Zheng LS, Cao L, Yang JP, Wang MY, Mei Y, Qiang YY, Zhang ZM, Yun JP, Huang BJ, Qian CN.

J Exp Clin Cancer Res. 2017 Jan 28;36(1):21. doi: 10.1186/s13046-016-0483-z. Erratum in: J Exp Clin Cancer Res. 2017 Feb 20;36(1):33.


RNA-binding protein QKI-5 inhibits the proliferation of clear cell renal cell carcinoma via post-transcriptional stabilization of RASA1 mRNA.

Zhang RL, Yang JP, Peng LX, Zheng LS, Xie P, Wang MY, Cao Y, Zhang ZL, Zhou FJ, Qian CN, Bao YX.

Cell Cycle. 2016 Nov 16;15(22):3094-3104. Epub 2016 Oct 21.


SPINK6 Promotes Metastasis of Nasopharyngeal Carcinoma via Binding and Activation of Epithelial Growth Factor Receptor.

Zheng LS, Yang JP, Cao Y, Peng LX, Sun R, Xie P, Wang MY, Meng DF, Luo DH, Zou X, Chen MY, Mai HQ, Guo L, Guo X, Shao JY, Huang BJ, Zhang W, Qian CN.

Cancer Res. 2017 Jan 15;77(2):579-589. doi: 10.1158/0008-5472.CAN-16-1281. Epub 2016 Sep 26.


Aponeurosis of the levator palpebrae superioris in Chinese subjects: A live gross anatomy and cadaveric histological study.

Pan E, Nie YF, Wang ZJ, Peng LX, Wu YH, Li Q.

Medicine (Baltimore). 2016 Aug;95(31):e4469. doi: 10.1097/MD.0000000000004469.


Corrigendum: A splicing switch from ketohexokinase-C to ketohexokinase-A drives hepatocellular carcinoma formation.

Li X, Qian X, Peng LX, Jiang Y, Hawke DH, Zheng Y, Xia Y, Lee JH, Cote G, Wang H, Wang L, Qian CN, Lu Z.

Nat Cell Biol. 2016 May 27;18(6):709. doi: 10.1038/ncb3361. No abstract available.


Pharmacokinetic study of eplerenone in rats after long-term coadministration with buckwheat tea.

Zou L, Jia K, Li R, Wang P, Lin JZ, Chen HJ, Zhao G, Peng LX.

Kaohsiung J Med Sci. 2016 Apr;32(4):177-84. doi: 10.1016/j.kjms.2016.03.004. Epub 2016 Apr 24.


A splicing switch from ketohexokinase-C to ketohexokinase-A drives hepatocellular carcinoma formation.

Li X, Qian X, Peng LX, Jiang Y, Hawke DH, Zheng Y, Xia Y, Lee JH, Cote G, Wang H, Wang L, Qian CN, Lu Z.

Nat Cell Biol. 2016 May;18(5):561-71. doi: 10.1038/ncb3338. Epub 2016 Apr 18. Erratum in: Nat Cell Biol. 2016 May 27;18(6):709.


PDZ binding kinase (PBK) is a theranostic target for nasopharyngeal carcinoma: driving tumor growth via ROS signaling and correlating with patient survival.

Wang MY, Lin ZR, Cao Y, Zheng LS, Peng LX, Sun R, Meng DF, Xie P, Yang JP, Cao L, Xu L, Huang BJ, Qian CN.

Oncotarget. 2016 May 3;7(18):26604-16. doi: 10.18632/oncotarget.8445.


Flavonoids, Antioxidant Activity and Aroma Compounds Analysis from Different Kinds of Tartary Buckwheat Tea.

Peng LX, Zou L, Wang JB, Zhao JL, Xiang DB, Zhao G.

Indian J Pharm Sci. 2015 Nov-Dec;77(6):661-7.


Tumor vasculogenic mimicry predicts poor prognosis in cancer patients: a meta-analysis.

Yang JP, Liao YD, Mai DM, Xie P, Qiang YY, Zheng LS, Wang MY, Mei Y, Meng DF, Xu L, Cao L, Yang Q, Yang XX, Wang WB, Peng LX, Huang BJ, Qian CN.

Angiogenesis. 2016 Apr;19(2):191-200. doi: 10.1007/s10456-016-9500-2. Epub 2016 Feb 22.


IL-8 suppresses E-cadherin expression in nasopharyngeal carcinoma cells by enhancing E-cadherin promoter DNA methylation.

Zhang RL, Peng LX, Yang JP, Zheng LS, Xie P, Wang MY, Huang BJ, Zhao HR, Bao YX, Qian CN.

Int J Oncol. 2016 Jan;48(1):207-14. doi: 10.3892/ijo.2015.3226. Epub 2015 Nov 2.


Phosphoinositide 3-kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells.

Peng LX, Zhao P, Zhao HS, Pan E, Yang BB, Li Q.

Mol Med Rep. 2015 Dec;12(6):8275-81. doi: 10.3892/mmr.2015.4447. Epub 2015 Oct 15.


Polymorphism in miR-146a associated with clinical characteristics and outcomes in gastric cancer patients treated with adjuvant oxaliplatin and fluoropyrimidines.

Liao YQ, Liao YL, Li J, Peng LX, Wan YY, Zhong R.

Onco Targets Ther. 2015 Sep 16;8:2627-33. doi: 10.2147/OTT.S89635. eCollection 2015.


[In vitro transdermal delivery of Qingfei Xiaocuo gel based on principal component analysis].

Ren WG, Peng LX, Lei FF, Sun CX, Pan JH.

Zhongguo Zhong Yao Za Zhi. 2015 Jan;40(2):231-5. Chinese.


WNT5A promotes stemness characteristics in nasopharyngeal carcinoma cells leading to metastasis and tumorigenesis.

Qin L, Yin YT, Zheng FJ, Peng LX, Yang CF, Bao YN, Liang YY, Li XJ, Xiang YQ, Sun R, Li AH, Zou RH, Pei XQ, Huang BJ, Kang TB, Liao DF, Zeng YX, Williams BO, Qian CN.

Oncotarget. 2015 Apr 30;6(12):10239-52.


Efficient production of flavonoids in Fagopyrum tataricum hairy root cultures with yeast polysaccharide elicitation and medium renewal process.

Zhao JL, Zou L, Zhang CQ, Li YY, Peng LX, Xiang DB, Zhao G.

Pharmacogn Mag. 2014 Jul;10(39):234-40. doi: 10.4103/0973-1296.137362.


Monoacylglycerol lipase promotes metastases in nasopharyngeal carcinoma.

Hu WR, Lian YF, Peng LX, Lei JJ, Deng CC, Xu M, Feng QS, Chen LZ, Bei JX, Zeng YX.

Int J Clin Exp Pathol. 2014 Jun 15;7(7):3704-13. eCollection 2014.


Downregulation of Ras association domain family member 6 (RASSF6) underlies the treatment resistance of highly metastatic nasopharyngeal carcinoma cells.

Liang YY, Chen MY, Hua YJ, Chen S, Zheng LS, Cao X, Peng LX, Xie P, Huang BJ, Sun R, Wang L, Xiang YQ, Guo X, Qian CN.

PLoS One. 2014 Jul 16;9(7):e100843. doi: 10.1371/journal.pone.0100843. eCollection 2014.


A prognostic classifier consisting of 17 circulating cytokines is a novel predictor of overall survival for metastatic colorectal cancer patients.

Chen ZY, He WZ, Peng LX, Jia WH, Guo RP, Xia LP, Qian CN.

Int J Cancer. 2015 Feb 1;136(3):584-92. doi: 10.1002/ijc.29017. Epub 2014 Jun 24.


Urokinase-type plasminogen activator receptor signaling is critical in nasopharyngeal carcinoma cell growth and metastasis.

Bao YN, Cao X, Luo DH, Sun R, Peng LX, Wang L, Yan YP, Zheng LS, Xie P, Cao Y, Liang YY, Zheng FJ, Huang BJ, Xiang YQ, Lv X, Chen QY, Chen MY, Huang PY, Guo L, Mai HQ, Guo X, Zeng YX, Qian CN.

Cell Cycle. 2014;13(12):1958-69. doi: 10.4161/cc.28921. Epub 2014 Apr 24.


RASSF6 promotes p21(Cip1/Waf1)-dependent cell cycle arrest and apoptosis through activation of the JNK/SAPK pathway in clear cell renal cell carcinoma.

Liang YY, Zheng LS, Wu YZ, Peng LX, Cao Y, Cao X, Xie P, Huang BJ, Qian CN.

Cell Cycle. 2014;13(9):1440-9. doi: 10.4161/cc.28416. Epub 2014 Mar 10.


[Molecular evolution of the sulphite efflux gene SSU1 in Saccharomyces cerevisiae].

Peng LX, Sun FF, Huang YY, Li ZC.

Yi Chuan. 2013 Nov;35(11):1317-26. Chinese.


The free energy profile of tubulin straight-bent conformational changes, with implications for microtubule assembly and drug discovery.

Peng LX, Hsu MT, Bonomi M, Agard DA, Jacobson MP.

PLoS Comput Biol. 2014 Feb 6;10(2):e1003464. doi: 10.1371/journal.pcbi.1003464. eCollection 2014 Feb.


Using multiple cytokines to predict hepatocellular carcinoma recurrence in two patient cohorts.

Chen ZY, Wei W, Guo ZX, Peng LX, Shi M, Li SH, Xiao CZ, Zhong C, Qian CN, Guo RP.

Br J Cancer. 2014 Feb 4;110(3):733-40. doi: 10.1038/bjc.2013.781. Epub 2013 Dec 17.


Cancer stem-like cell characteristics induced by EB virus-encoded LMP1 contribute to radioresistance in nasopharyngeal carcinoma by suppressing the p53-mediated apoptosis pathway.

Yang CF, Peng LX, Huang TJ, Yang GD, Chu QQ, Liang YY, Cao X, Xie P, Zheng LS, Huang HB, Cai MD, Huang JL, Liu RY, Zhu ZY, Qian CN, Huang BJ.

Cancer Lett. 2014 Mar 28;344(2):260-71. doi: 10.1016/j.canlet.2013.11.006. Epub 2013 Nov 19.


Epstein-Barr Virus_Encoded LMP1 upregulates microRNA-21 to promote the resistance of nasopharyngeal carcinoma cells to cisplatin-induced Apoptosis by suppressing PDCD4 and Fas-L.

Yang GD, Huang TJ, Peng LX, Yang CF, Liu RY, Huang HB, Chu QQ, Yang HJ, Huang JL, Zhu ZY, Qian CN, Huang BJ.

PLoS One. 2013 Oct 23;8(10):e78355. doi: 10.1371/journal.pone.0078355. eCollection 2013.


Comprehensive profiling of Epstein-Barr virus-encoded miRNA species associated with specific latency types in tumor cells.

Yang HJ, Huang TJ, Yang CF, Peng LX, Liu RY, Yang GD, Chu QQ, Huang JL, Liu N, Huang HB, Zhu ZY, Qian CN, Huang BJ.

Virol J. 2013 Oct 26;10:314. doi: 10.1186/1743-422X-10-314.


[Simulation experiment of survival and reproduction of artificially imported Oncomelania snails in Qingpu District, Shanghai].

Tian JG, Li GF, Li J, Zhang XP, Jin YJ, Cai L, Peng LX, Xu HY, Xu RF.

Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2013 Jun;25(3):322-3. Chinese.


The study of absorption kinetics of berberine based on portal vein in rat, and the influence of verapamil and borneol to its absorption ability by UHPLC method.

Zou L, Li R, Wang P, Xiao Y, Xu LJ, He YX, Zhao G, Peng LX.

Eur J Drug Metab Pharmacokinet. 2014 Sep;39(3):165-71. doi: 10.1007/s13318-013-0152-y. Epub 2013 Sep 7.


Response surface modeling and optimization of ultrasound-assisted extraction of three flavonoids from tartary buckwheat (Fagopyrum tataricum).

Peng LX, Zou L, Zhao JL, Xiang DB, Zhu P, Zhao G.

Pharmacogn Mag. 2013 Jul;9(35):210-5. doi: 10.4103/0973-1296.113266.


Rapid and simple method for the determination of emodin in tartary buckwheat (Fagopyrum tataricum) by high-performance liquid chromatography coupled to a diode array detector.

Peng LX, Wang JB, Hu LX, Zhao JL, Xiang DB, Zou L, Zhao G.

J Agric Food Chem. 2013 Jan 30;61(4):854-7. doi: 10.1021/jf304804c. Epub 2013 Jan 22.


Dovitinib preferentially targets endothelial cells rather than cancer cells for the inhibition of hepatocellular carcinoma growth and metastasis.

Chen ZY, Shi M, Peng LX, Wei W, Li XJ, Guo ZX, Li SH, Zhong C, Qian CN, Guo RP.

J Transl Med. 2012 Dec 10;10:245. doi: 10.1186/1479-5876-10-245.


[Impact of artesunate on the expression and secretion of transforming growth factor-b1 of primary rat hepatic stellate cells].

Wang Y, Fang BW, Peng LX.

Zhonghua Gan Zang Bing Za Zhi. 2012 Apr;20(4):294-9. doi: 10.3760/cma.j.issn.1007-3418.2012.04.014. Chinese.


As an independent unfavorable prognostic factor, IL-8 promotes metastasis of nasopharyngeal carcinoma through induction of epithelial-mesenchymal transition and activation of AKT signaling.

Li XJ, Peng LX, Shao JY, Lu WH, Zhang JX, Chen S, Chen ZY, Xiang YQ, Bao YN, Zheng FJ, Zeng MS, Kang TB, Zeng YX, Teh BT, Qian CN.

Carcinogenesis. 2012 Jul;33(7):1302-9. doi: 10.1093/carcin/bgs181. Epub 2012 May 18.


[Preliminary observation on survival and reproduction of imported Oncomelania snails in water network regions: a simulated experiment].

Tian JG, Zhong WJ, Li GF, Peng LX, Xiang XP.

Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2011 Apr;23(2):204-6. Chinese.


Aggregation properties of a polymeric anticancer therapeutic: a coarse-grained modeling study.

Peng LX, Yu L, Howell SB, Gough DA.

J Chem Inf Model. 2011 Dec 27;51(12):3030-5. doi: 10.1021/ci200214m. Epub 2011 Nov 21.


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