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Items: 1 to 50 of 58

1.

Immunological profiling of key inflammatory drivers of nasal polyp formation and growth in chronic rhinosinusitis.

Biggs TC, Hayes SM, Harries PG, Allan RN, Walls AF, Pender SLF, Salib RJ.

Rhinology. 2019 Oct 1;57(5):336-342. doi: 10.4193/Rhin19.167.

PMID:
31317972
2.

Staphylococcus aureus internalization in mast cells in nasal polyps: Characterization of interactions and potential mechanisms.

Hayes SM, Biggs TC, Goldie SP, Harries PG, Walls AF, Allan RN, Pender SLF, Salib RJ.

J Allergy Clin Immunol. 2020 Jan;145(1):147-159. doi: 10.1016/j.jaci.2019.06.013. Epub 2019 Jun 27.

PMID:
31254531
3.

Relationships Between Ion Channels, Mitochondrial Functions and Inflammation in Human Aging.

Strickland M, Yacoubi-Loueslati B, Bouhaouala-Zahar B, Pender SLF, Larbi A.

Front Physiol. 2019 Mar 1;10:158. doi: 10.3389/fphys.2019.00158. eCollection 2019. Review.

4.

Adaptive NKG2C+CD57+ Natural Killer Cell and Tim-3 Expression During Viral Infections.

Kared H, Martelli S, Tan SW, Simoni Y, Chong ML, Yap SH, Newell EW, Pender SLF, Kamarulzaman A, Rajasuriar R, Larbi A.

Front Immunol. 2018 Apr 20;9:686. doi: 10.3389/fimmu.2018.00686. eCollection 2018.

5.

Neutrophilia, gelatinase release and microvascular leakage induced by human mast cell tryptase in a mouse model: Lack of a role of protease-activated receptor 2 (PAR2).

Khedr MEMS, Abdelmotelb AM, Pender SLF, Zhou X, Walls AF.

Clin Exp Allergy. 2018 May;48(5):555-567. doi: 10.1111/cea.13108.

6.

The application of silver nano-particles on developing potential treatment for chronic rhinosinusitis: Antibacterial action and cytotoxicity effect on human nasal epithelial cell model.

Chen SY, Huang MT, Pender SLF, Ruslin M, Chou HH, Ou KL.

Mater Sci Eng C Mater Biol Appl. 2017 Nov 1;80:624-630. doi: 10.1016/j.msec.2017.03.189. Epub 2017 Mar 22.

PMID:
28866209
7.

Hot topics in reactive oxygen therapy: Antimicrobial and immunological mechanisms, safety and clinical applications.

Dryden M, Cooke J, Salib R, Holding R, Pender SLF, Brooks J.

J Glob Antimicrob Resist. 2017 Mar;8:194-198. doi: 10.1016/j.jgar.2016.12.012. Epub 2017 Feb 17. Review.

PMID:
28219826
8.

CD57 in human natural killer cells and T-lymphocytes.

Kared H, Martelli S, Ng TP, Pender SL, Larbi A.

Cancer Immunol Immunother. 2016 Apr;65(4):441-52. doi: 10.1007/s00262-016-1803-z. Epub 2016 Feb 5. Review.

PMID:
26850637
9.

Compartmentalization of immunosenescence: a deeper look at the mucosa.

Martelli S, Pender SL, Larbi A.

Biogerontology. 2016 Feb;17(1):159-76. doi: 10.1007/s10522-015-9628-2. Epub 2015 Dec 21. Review.

PMID:
26689202
10.

Abnormal thymic stromal lymphopoietin expression in the duodenal mucosa of patients with coeliac disease.

Biancheri P, Di Sabatino A, Rescigno M, Giuffrida P, Fornasa G, Tsilingiri K, Pender SL, Papadia C, Wood E, Pasini A, Ubezio C, Vanoli A, Forbes A, MacDonald TT, Corazza GR.

Gut. 2016 Oct;65(10):1670-80. doi: 10.1136/gutjnl-2014-308876. Epub 2015 Sep 4.

11.

Intracellular residency of Staphylococcus aureus within mast cells in nasal polyps: A novel observation.

Hayes SM, Howlin R, Johnston DA, Webb JS, Clarke SC, Stoodley P, Harries PG, Wilson SJ, Pender SL, Faust SN, Hall-Stoodley L, Salib RJ.

J Allergy Clin Immunol. 2015 Jun;135(6):1648-51. doi: 10.1016/j.jaci.2014.12.1929. Epub 2015 Feb 11. No abstract available.

PMID:
25680455
12.

Chronic inflammation induces telomere dysfunction and accelerates ageing in mice.

Jurk D, Wilson C, Passos JF, Oakley F, Correia-Melo C, Greaves L, Saretzki G, Fox C, Lawless C, Anderson R, Hewitt G, Pender SL, Fullard N, Nelson G, Mann J, van de Sluis B, Mann DA, von Zglinicki T.

Nat Commun. 2014 Jun 24;2:4172. doi: 10.1038/ncomms5172.

13.

The role of interleukin 17 in Crohn's disease-associated intestinal fibrosis.

Biancheri P, Pender SL, Ammoscato F, Giuffrida P, Sampietro G, Ardizzone S, Ghanbari A, Curciarello R, Pasini A, Monteleone G, Corazza GR, Macdonald TT, Di Sabatino A.

Fibrogenesis Tissue Repair. 2013 Jul 8;6(1):13. doi: 10.1186/1755-1536-6-13.

14.

Influence of matrix metalloproteinase-12 on fibrinogen level.

Motterle A, Xiao Q, Kiechl S, Pender SL, Morris GE, Willeit J, Caulfield MJ, Ye S.

Atherosclerosis. 2012 Feb;220(2):351-4. doi: 10.1016/j.atherosclerosis.2011.11.003. Epub 2011 Nov 11.

PMID:
22119538
15.

Histone deacetylase inhibitors and their potential role in inflammatory bowel diseases.

Edwards AJ, Pender SL.

Biochem Soc Trans. 2011 Aug;39(4):1092-5. doi: 10.1042/BST0391092.

PMID:
21787354
16.

Role of meprins to protect ileal mucosa of Crohn's disease patients from colonization by adherent-invasive E. coli.

Vazeille E, Bringer MA, Gardarin A, Chambon C, Becker-Pauly C, Pender SL, Jakob C, Müller S, Lottaz D, Darfeuille-Michaud A.

PLoS One. 2011;6(6):e21199. doi: 10.1371/journal.pone.0021199. Epub 2011 Jun 16.

17.

The endogenous cannabinoid system in the gut of patients with inflammatory bowel disease.

Di Sabatino A, Battista N, Biancheri P, Rapino C, Rovedatti L, Astarita G, Vanoli A, Dainese E, Guerci M, Piomelli D, Pender SL, MacDonald TT, Maccarrone M, Corazza GR.

Mucosal Immunol. 2011 Sep;4(5):574-83. doi: 10.1038/mi.2011.18. Epub 2011 Apr 6. Erratum in: Mucosal Immunol. 2011 Jul4(4):479.

18.

CC-10004 but not thalidomide or lenalidomide inhibits lamina propria mononuclear cell TNF-α and MMP-3 production in patients with inflammatory bowel disease.

Gordon JN, Prothero JD, Thornton CA, Pickard KM, Di Sabatino A, Goggin PM, Pender SL, Macdonald TT.

J Crohns Colitis. 2009 Sep;3(3):175-82. doi: 10.1016/j.crohns.2009.03.001. Epub 2009 Apr 10.

PMID:
21172267
19.

Stromelysin-1 and macrophage metalloelastase expression in the intestinal mucosa of Crohn's disease patients treated with infliximab.

Di Sabatino A, Saarialho-Kere U, Buckley MG, Gordon JN, Biancheri P, Rovedatti L, Corazza GR, Macdonald TT, Pender SL.

Eur J Gastroenterol Hepatol. 2009 Sep;21(9):1049-55. doi: 10.1097/MEG.0b013e3283293d0f.

PMID:
19357521
20.

Transforming growth factor beta signalling and matrix metalloproteinases in the mucosa overlying Crohn's disease strictures.

Di Sabatino A, Jackson CL, Pickard KM, Buckley M, Rovedatti L, Leakey NA, Picariello L, Cazzola P, Monteleone G, Tonelli F, Corazza GR, MacDonald TT, Pender SL.

Gut. 2009 Jun;58(6):777-89. doi: 10.1136/gut.2008.149096. Epub 2009 Feb 6.

PMID:
19201776
21.

Do metalloproteinases contribute to tissue destruction or remodeling in the inflamed gut?

Pender SL.

Inflamm Bowel Dis. 2008 Oct;14 Suppl 2:S136-7. doi: 10.1002/ibd.20630. No abstract available. Erratum in: Inflamm Bowel Dis. 2009 Sep;15(9):1438-47.

PMID:
18816739
22.

Matrix metalloproteinase-3 production by gut IgG plasma cells in chronic inflammatory bowel disease.

Gordon JN, Pickard KM, Di Sabatino A, Prothero JD, Pender SL, Goggin PM, MacDonald TT.

Inflamm Bowel Dis. 2008 Feb;14(2):195-203.

PMID:
18022869
23.

Functional modulation of Crohn's disease myofibroblasts by anti-tumor necrosis factor antibodies.

Di Sabatino A, Pender SL, Jackson CL, Prothero JD, Gordon JN, Picariello L, Rovedatti L, Docena G, Monteleone G, Rampton DS, Tonelli F, Corazza GR, MacDonald TT.

Gastroenterology. 2007 Jul;133(1):137-49. Epub 2007 May 5.

PMID:
17631138
24.

Role of macrophage metalloelastase in gut inflammation.

Pender SL, Li CK, Di Sabatino A, MacDonald TT, Buckley MG.

Ann N Y Acad Sci. 2006 Aug;1072:386-8. Erratum in: Ann N Y Acad Sci. 2008 Apr;1126:333. Sabatino, A D I [corrected to Di Sabatino, A].

PMID:
17057219
25.

Myofibroblast matrix metalloproteinases activate the neutrophil chemoattractant CXCL7 from intestinal epithelial cells.

Kruidenier L, MacDonald TT, Collins JE, Pender SL, Sanderson IR.

Gastroenterology. 2006 Jan;130(1):127-36.

PMID:
16401476
26.

Systemic administration of the chemokine macrophage inflammatory protein 1alpha exacerbates inflammatory bowel disease in a mouse model.

Pender SL, Chance V, Whiting CV, Buckley M, Edwards M, Pettipher R, MacDonald TT.

Gut. 2005 Aug;54(8):1114-20.

27.

Collagenase-1 (MMP-1), matrilysin-1 (MMP-7), and stromelysin-2 (MMP-10) are expressed by migrating enterocytes during intestinal wound healing.

Salmela MT, Pender SL, Karjalainen-Lindsberg ML, Puolakkainen P, Macdonald TT, Saarialho-Kere U.

Scand J Gastroenterol. 2004 Nov;39(11):1095-104.

PMID:
15545168
28.

Matrix metalloproteinases and the gut - new roles for old enzymes.

Pender SL, MacDonald TT.

Curr Opin Pharmacol. 2004 Dec;4(6):546-50. Review.

PMID:
15525541
29.

Impaired immunity to intestinal bacterial infection in stromelysin-1 (matrix metalloproteinase-3)-deficient mice.

Li CK, Pender SL, Pickard KM, Chance V, Holloway JA, Huett A, Gonçalves NS, Mudgett JS, Dougan G, Frankel G, MacDonald TT.

J Immunol. 2004 Oct 15;173(8):5171-9.

30.

Transmission disequilibrium test of stromelysin-1 gene variation in relation to Crohn's disease.

Pender SL, Croucher PJ, Mascheretti S, Prothero JD, Fisher SA, MacDonald TT, Schreiber S, Ye S.

J Med Genet. 2004 Sep;41(9):e112. No abstract available.

31.

Up-regulation of collagen and tissue inhibitors of matrix metalloproteinase in colonic diverticular disease.

Mimura T, Bateman AC, Lee RL, Johnson PA, McDonald PJ, Talbot IC, Kamm MA, MacDonald TT, Pender SL.

Dis Colon Rectum. 2004 Mar;47(3):371-8; discussion 378-9.

PMID:
14991500
32.

Matrix metalloproteinases in necrotising enterocolitis.

Pender SL, Braegger C, Gunther U, Monteleone G, Meuli M, Schuppan D, Macdonald TT.

Pediatr Res. 2003 Aug;54(2):160-4. Epub 2003 May 7.

PMID:
12736398
33.

Activated STAT4 and a functional role for IL-12 in human Peyer's patches.

Monteleone G, Holloway J, Salvati VM, Pender SL, Fairclough PD, Croft N, MacDonald TT.

J Immunol. 2003 Jan 1;170(1):300-7.

34.

Upregulation of matrix metalloproteinases in a model of T cell mediated tissue injury in the gut: analysis by gene array and in situ hybridisation.

Salmela MT, MacDonald TT, Black D, Irvine B, Zhuma T, Saarialho-Kere U, Pender SL.

Gut. 2002 Oct;51(4):540-7.

35.

Expression of transforming growth factor-beta 1 by pancreatic stellate cells and its implications for matrix secretion and turnover in chronic pancreatitis.

Shek FW, Benyon RC, Walker FM, McCrudden PR, Pender SL, Williams EJ, Johnson PA, Johnson CD, Bateman AC, Fine DR, Iredale JP.

Am J Pathol. 2002 May;160(5):1787-98.

36.

Matrix metalloproteinases and their inhibitors in the nasal mucosa of patients with perennial allergic rhinitis.

Shaida A, Kenyon G, Devalia J, Davies RJ, MacDonald TT, Pender SL.

J Allergy Clin Immunol. 2001 Nov;108(5):791-6.

PMID:
11692106
37.

Costimulatory molecules in the developing human gastrointestinal tract: a pathway for fetal allergen priming.

Jones CA, Vance GH, Power LL, Pender SL, Macdonald TT, Warner JO.

J Allergy Clin Immunol. 2001 Aug;108(2):235-41.

PMID:
11496240
38.

Interferon-alpha drives T cell-mediated immunopathology in the intestine.

Monteleone G, Pender SL, Wathen NC, MacDonald TT.

Eur J Immunol. 2001 Aug;31(8):2247-55.

39.

Parallel expression of macrophage metalloelastase (MMP-12) in duodenal and skin lesions of patients with dermatitis herpetiformis.

Salmela MT, Pender SL, Reunala T, MacDonald T, Saarialho-Kere U.

Gut. 2001 Apr;48(4):496-502.

40.

Role of interferon alpha in promoting T helper cell type 1 responses in the small intestine in coeliac disease.

Monteleone G, Pender SL, Alstead E, Hauer AC, Lionetti P, McKenzie C, MacDonald TT.

Gut. 2001 Mar;48(3):425-9. Erratum in: Gut 2001 Apr;48(4):584.

41.

Ligation of alpha4ss1 integrin on human intestinal mucosal mesenchymal cells selectively Up-regulates membrane type-1 matrix metalloproteinase and confers a migratory phenotype.

Pender SL, Salmela MT, Monteleone G, Schnapp D, McKenzie C, Spencer J, Fong S, Saarialho-Kere U, MacDonald TT.

Am J Pathol. 2000 Dec;157(6):1955-62.

42.

Butyrate upregulates stromelysin-1 production by intestinal mesenchymal cells.

Pender SL, Quinn JJ, Sanderson IR, MacDonald TT.

Am J Physiol Gastrointest Liver Physiol. 2000 Nov;279(5):G918-24.

43.

Human Peyer's patch T cells are sensitized to dietary antigen and display a Th cell type 1 cytokine profile.

Nagata S, McKenzie C, Pender SL, Bajaj-Elliott M, Fairclough PD, Walker-Smith JA, Monteleone G, MacDonald TT.

J Immunol. 2000 Nov 1;165(9):5315-21.

44.

Imbalance of stromelysin-1 and TIMP-1 in the mucosal lesions of children with inflammatory bowel disease.

Heuschkel RB, MacDonald TT, Monteleone G, Bajaj-Elliott M, Smith JA, Pender SL.

Gut. 2000 Jul;47(1):57-62.

45.

Recent developments in the immunology of inflammatory bowel disease.

MacDonald TT, Monteleone G, Pender SL.

Scand J Immunol. 2000 Jan;51(1):2-9. Review.

46.

Enhancing Lamina propria Th1 cell responses with interleukin 12 produces severe tissue injury.

Monteleone G, MacDonald TT, Wathen NC, Pallone F, Pender SL.

Gastroenterology. 1999 Nov;117(5):1069-77.

PMID:
10535869
47.

T cells orchestrate intestinal mucosal shape and integrity.

MacDonald TT, Bajaj-Elliott M, Pender SL.

Immunol Today. 1999 Nov;20(11):505-10. Review. No abstract available.

PMID:
10529778
48.

Regulation of matrix metalloproteinases in human intestinal mucosa.

Pender SL, McKenzie C, Shaida A, MacDonald TT.

Ann N Y Acad Sci. 1999 Jun 30;878:581-2. No abstract available.

PMID:
10415779
50.

Upregulation of keratinocyte growth factor during T-cell immunity in the gut mucosa.

Bajaj-Elliott M, Pender SL, Poulsom R, Macdonald TT.

Ann N Y Acad Sci. 1998 Nov 17;859:184-7. No abstract available.

PMID:
9928382

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