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Items: 22


Rapid Induction of Liver Regeneration for Major Hepatectomy (REBIRTH): A Randomized Controlled Trial of Portal Vein Embolisation versus ALPPS Assisted with Radiofrequency.

Jiao LR, Fajardo Puerta AB, Gall TMH, Sodergren MH, Frampton AE, Pencavel T, Nagendran M, Habib NA, Darzi A, Pai M, Thomas R, Tait P.

Cancers (Basel). 2019 Mar 4;11(3). pii: E302. doi: 10.3390/cancers11030302.


Regional chemotherapy by isolated limb perfusion prior to surgery compared with surgery and post-operative radiotherapy for primary, locally advanced extremity sarcoma: a comparison of matched cohorts.

Jakob J, Smith HG, Wilkinson MJ, Pencavel T, Miah AB, Thomas JM, Tunn PU, Pilz LR, Strauss DC, Hohenberger P, Hayes AJ.

Clin Sarcoma Res. 2018 Jul 2;8:12. doi: 10.1186/s13569-018-0098-6. eCollection 2018.


Genetically modified lentiviruses that preserve microvascular function protect against late radiation damage in normal tissues.

Khan AA, Paget JT, McLaughlin M, Kyula JN, Wilkinson MJ, Pencavel T, Mansfield D, Roulstone V, Seth R, Halle M, Somaiah N, Boult JKR, Robinson SP, Pandha HS, Vile RG, Melcher AA, Harris PA, Harrington KJ.

Sci Transl Med. 2018 Jan 24;10(425). pii: eaar2041. doi: 10.1126/scitranslmed.aar2041.


Portal hypertension and chylous ascites complicating acute pancreatitis: the therapeutic value of portal vein stenting.

Poo S, Pencavel TD, Jackson J, Jiao LR.

Ann R Coll Surg Engl. 2018 Jan;100(1):e1-e3. doi: 10.1308/rcsann.2017.0078. Epub 2017 Oct 19.


Oncolytic vaccinia virus combined with radiotherapy induces apoptotic cell death in sarcoma cells by down-regulating the inhibitors of apoptosis.

Wilkinson MJ, Smith HG, McEntee G, Kyula-Currie J, Pencavel TD, Mansfield DC, Khan AA, Roulstone V, Hayes AJ, Harrington KJ.

Oncotarget. 2016 Dec 6;7(49):81208-81222. doi: 10.18632/oncotarget.12820.


Isolated limb perfusion with biochemotherapy and oncolytic virotherapy combines with radiotherapy and surgery to overcome treatment resistance in an animal model of extremity soft tissue sarcoma.

Wilkinson MJ, Smith HG, Pencavel TD, Mansfield DC, Kyula-Currie J, Khan AA, McEntee G, Roulstone V, Hayes AJ, Harrington KJ.

Int J Cancer. 2016 Sep 15;139(6):1414-22. doi: 10.1002/ijc.30162. Epub 2016 May 24.


Adenovirally delivered enzyme prodrug therapy with herpes simplex virus-thymidine kinase in composite tissue free flaps shows therapeutic efficacy in rat models of glioma.

Seth R, Khan AA, Pencavel TD, Wilkinson MJ, Kyula JN, Simpson G, Pandha H, Melcher A, Vile R, Harris PA, Harrington KJ.

Plast Reconstr Surg. 2015 Feb;135(2):475-87. doi: 10.1097/PRS.0000000000000878.


Isolated limb perfusion with melphalan, tumour necrosis factor-alpha and oncolytic vaccinia virus improves tumour targeting and prolongs survival in a rat model of advanced extremity sarcoma.

Pencavel TD, Wilkinson MJ, Mansfield DC, Khan AA, Seth R, Karapanagiotou EM, Roulstone V, Aguilar RJ, Chen NG, Szalay AA, Hayes AJ, Harrington KJ.

Int J Cancer. 2015 Feb 15;136(4):965-76. doi: 10.1002/ijc.29059. Epub 2014 Jul 22.


Successful thrombolysis of a late acute thrombotic occlusion of an aortic prosthesis after endovascular aneurysm repair.

Waiting J, Dias A, Patel T, Pencavel T, Rosenfeld K, Sarin S.

Ann Vasc Surg. 2014 Oct;28(7):1791.e1-4. doi: 10.1016/j.avsg.2014.02.027. Epub 2014 Mar 12.


Optimising measles virus-guided radiovirotherapy with external beam radiotherapy and specific checkpoint kinase 1 inhibition.

Touchefeu Y, Khan AA, Borst G, Zaidi SH, McLaughlin M, Roulstone V, Mansfield D, Kyula J, Pencavel T, Karapanagiotou EM, Clayton J, Federspiel MJ, Russell SJ, Garrett M, Collins I, Harrington KJ.

Radiother Oncol. 2013 Jul;108(1):24-31. doi: 10.1016/j.radonc.2013.05.036. Epub 2013 Jul 9.


Synergistic cytotoxicity of radiation and oncolytic Lister strain vaccinia in (V600D/E)BRAF mutant melanoma depends on JNK and TNF-α signaling.

Kyula JN, Khan AA, Mansfield D, Karapanagiotou EM, McLaughlin M, Roulstone V, Zaidi S, Pencavel T, Touchefeu Y, Seth R, Chen NG, Yu YA, Zhang Q, Melcher AA, Vile RG, Pandha HS, Ajaz M, Szalay AA, Harrington KJ.

Oncogene. 2014 Mar 27;33(13):1700-12. doi: 10.1038/onc.2013.112. Epub 2013 Apr 29.


Targeted gene delivery by free-tissue transfer in oncoplastic reconstruction.

Seth R, Khan AA, Pencavel T, Harrington KJ, Harris PA.

Lancet Oncol. 2012 Sep;13(9):e392-402. doi: 10.1016/S1470-2045(12)70235-8. Review.


Oncolytic Vaccinia virus and radiotherapy in head and neck cancer.

Mansfield D, Pencavel T, Kyula JN, Zaidi S, Roulstone V, Thway K, Karapanagiotou L, Khan AA, McLaughlin M, Touchefeu Y, Seth R, Melcher AA, Vile RG, Pandha HS, Harrington KJ.

Oral Oncol. 2013 Feb;49(2):108-18. doi: 10.1016/j.oraloncology.2012.07.019. Epub 2012 Aug 25.


Synergistic cytotoxicity of oncolytic reovirus in combination with cisplatin-paclitaxel doublet chemotherapy.

Roulstone V, Twigger K, Zaidi S, Pencavel T, Kyula JN, White C, McLaughlin M, Seth R, Karapanagiotou EM, Mansfield D, Coffey M, Nuovo G, Vile RG, Pandha HS, Melcher AA, Harrington KJ.

Gene Ther. 2013 May;20(5):521-8. doi: 10.1038/gt.2012.68. Epub 2012 Aug 16.


Combination of a fusogenic glycoprotein, pro-drug activation and oncolytic HSV as an intravesical therapy for superficial bladder cancer.

Simpson GR, Horvath A, Annels NE, Pencavel T, Metcalf S, Seth R, Peschard P, Price T, Coffin RS, Mostafid H, Melcher AA, Harrington KJ, Pandha HS.

Br J Cancer. 2012 Jan 31;106(3):496-507. doi: 10.1038/bjc.2011.577. Epub 2012 Jan 12.


Treatment for breast sarcoma: a large, single-centre series.

Pencavel T, Allan CP, Thomas JM, Hayes AJ.

Eur J Surg Oncol. 2011 Aug;37(8):703-8. doi: 10.1016/j.ejso.2011.04.006. Epub 2011 May 31.


Does the two-week rule pathway improve the diagnosis of soft tissue sarcoma? A retrospective review of referral patterns and outcomes over five years in a regional sarcoma centre.

Pencavel TD, Strauss DC, Thomas GP, Thomas JM, Hayes AJ.

Ann R Coll Surg Engl. 2010 Jul;92(5):417-21. doi: 10.1308/003588410X12664192075972. Epub 2010 May 19.


Locoregional intravascular viral therapy of cancer: precision guidance for Paris's arrow?

Pencavel T, Seth R, Hayes A, Melcher A, Pandha H, Vile R, Harrington KJ.

Gene Ther. 2010 Aug;17(8):949-60. doi: 10.1038/gt.2010.48. Epub 2010 May 6. Review.


The surgical management of soft tissue tumours arising in the abdominal wall.

Pencavel T, Strauss DC, Thomas JM, Hayes AJ.

Eur J Surg Oncol. 2010 May;36(5):489-95. doi: 10.1016/j.ejso.2010.03.007. Epub 2010 Apr 9.


Breast sarcoma--a review of diagnosis and management.

Pencavel TD, Hayes A.

Int J Surg. 2009 Feb;7(1):20-3. doi: 10.1016/j.ijsu.2008.12.005. Epub 2008 Dec 11. Review.


Conservative treatment of an early aortic graft infection due to Acinetobacter baumanii.

Pencavel TD, Singh-Ranger G, Crinnion JN.

Ann Vasc Surg. 2006 May;20(3):415-7. Epub 2006 Apr 7.


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