Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 65

1.

Proneural and mesenchymal glioma stem cells display major differences in splicing and lncRNA profiles.

Guardia GDA, Correa BR, Araujo PR, Qiao M, Burns S, Penalva LOF, Galante PAF.

NPJ Genom Med. 2020 Jan 16;5:2. doi: 10.1038/s41525-019-0108-5. eCollection 2020.

2.

Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis.

Zhu Z, Mesci P, Bernatchez JA, Gimple RC, Wang X, Schafer ST, Wettersten HI, Beck S, Clark AE, Wu Q, Prager BC, Kim LJY, Dhanwani R, Sharma S, Garancher A, Weis SM, Mack SC, Negraes PD, Trujillo CA, Penalva LO, Feng J, Lan Z, Zhang R, Wessel AW, Dhawan S, Diamond MS, Chen CC, Wechsler-Reya RJ, Gage FH, Hu H, Siqueira-Neto JL, Muotri AR, Cheresh DA, Rich JN.

Cell Stem Cell. 2020 Feb 6;26(2):187-204.e10. doi: 10.1016/j.stem.2019.11.016. Epub 2020 Jan 16.

PMID:
31956038
3.

ELF4 Is a Target of miR-124 and Promotes Neuroblastoma Proliferation and Undifferentiated State.

Kosti A, Du L, Shivram H, Qiao M, Burns S, Garcia JG, Pertsemlidis A, Iyer VR, Kokovay E, Penalva LOF.

Mol Cancer Res. 2020 Jan;18(1):68-78. doi: 10.1158/1541-7786.MCR-19-0187. Epub 2019 Oct 17.

PMID:
31624087
4.

The Diverse Roles of RNA-Binding Proteins in Glioma Development.

Velasco MX, Kosti A, Penalva LOF, Hernández G.

Adv Exp Med Biol. 2019;1157:29-39. doi: 10.1007/978-3-030-19966-1_2.

PMID:
31342436
5.

Antagonism between the RNA-binding protein Musashi1 and miR-137 and its potential impact on neurogenesis and glioblastoma development.

Velasco MX, Kosti A, Guardia GDA, Santos MC, Tegge A, Qiao M, Correa BRS, Hernández G, Kokovay E, Galante PAF, Penalva LOF.

RNA. 2019 Jul;25(7):768-782. doi: 10.1261/rna.069211.118. Epub 2019 Apr 19.

PMID:
31004009
6.

Luteolin inhibits Musashi1 binding to RNA and disrupts cancer phenotypes in glioblastoma cells.

Yi C, Li G, Ivanov DN, Wang Z, Velasco MX, Hernández G, Kaundal S, Villarreal J, Gupta YK, Qiao M, Hubert CG, Hart MJ, Penalva LOF.

RNA Biol. 2018;15(11):1420-1432. doi: 10.1080/15476286.2018.1539607. Epub 2018 Nov 18.

7.

Increased expression of the thyroid hormone nuclear receptor TRα1 characterizes intestinal tumors with high Wnt activity.

Uchuya-Castillo J, Aznar N, Frau C, Martinez P, Le Nevé C, Marisa L, Penalva LOF, Laurent-Puig P, Puisieux A, Scoazec JY, Samarut J, Ansieau S, Plateroti M.

Oncotarget. 2018 Jul 24;9(57):30979-30996. doi: 10.18632/oncotarget.25741. eCollection 2018 Jul 24.

8.

Patient-derived conditionally reprogrammed cells maintain intra-tumor genetic heterogeneity.

Correa BRS, Hu J, Penalva LOF, Schlegel R, Rimm DL, Galante PAF, Agarwal S.

Sci Rep. 2018 Mar 6;8(1):4097. doi: 10.1038/s41598-018-22427-1.

9.

The 3' end of the story: deciphering combinatorial interactions that control mRNA fate.

Sanford JR, Penalva LOF.

Genome Biol. 2017 Nov 29;18(1):227. doi: 10.1186/s13059-017-1360-6.

10.

MicroRNA-195 acts as an anti-proliferative miRNA in human melanoma cells by targeting Prohibitin 1.

Cirilo PDR, de Sousa Andrade LN, Corrêa BRS, Qiao M, Furuya TK, Chammas R, Penalva LOF.

BMC Cancer. 2017 Nov 10;17(1):750. doi: 10.1186/s12885-017-3721-7.

11.

From mechanisms to therapy: RNA processing's impact on human genetics.

Penalva LO, Sanford JR.

Hum Genet. 2017 Sep;136(9):1013-1014. doi: 10.1007/s00439-017-1841-4. No abstract available.

PMID:
28866814
12.

RNA processing as an alternative route to attack glioblastoma.

Marcelino Meliso F, Hubert CG, Favoretto Galante PA, Penalva LO.

Hum Genet. 2017 Sep;136(9):1129-1141. doi: 10.1007/s00439-017-1819-2. Epub 2017 Jun 12. Review.

13.

Riborex: fast and flexible identification of differential translation from Ribo-seq data.

Li W, Wang W, Uren PJ, Penalva LOF, Smith AD.

Bioinformatics. 2017 Jun 1;33(11):1735-1737. doi: 10.1093/bioinformatics/btx047.

14.

Musashi1 Impacts Radio-Resistance in Glioblastoma by Controlling DNA-Protein Kinase Catalytic Subunit.

de Araujo PR, Gorthi A, da Silva AE, Tonapi SS, Vo DT, Burns SC, Qiao M, Uren PJ, Yuan ZM, Bishop AJ, Penalva LO.

Am J Pathol. 2016 Sep;186(9):2271-8. doi: 10.1016/j.ajpath.2016.05.020. Epub 2016 Jul 25.

15.

Functional genomics analyses of RNA-binding proteins reveal the splicing regulator SNRPB as an oncogenic candidate in glioblastoma.

Correa BR, de Araujo PR, Qiao M, Burns SC, Chen C, Schlegel R, Agarwal S, Galante PA, Penalva LO.

Genome Biol. 2016 Jun 10;17(1):125. doi: 10.1186/s13059-016-0990-4.

16.

IGF2BP3 Modulates the Interaction of Invasion-Associated Transcripts with RISC.

Ennajdaoui H, Howard JM, Sterne-Weiler T, Jahanbani F, Coyne DJ, Uren PJ, Dargyte M, Katzman S, Draper JM, Wallace A, Cazarez O, Burns SC, Qiao M, Hinck L, Smith AD, Toloue MM, Blencowe BJ, Penalva LO, Sanford JR.

Cell Rep. 2016 May 31;15(9):1876-83. doi: 10.1016/j.celrep.2016.04.083. Epub 2016 May 19.

17.

High-throughput analyses of hnRNP H1 dissects its multi-functional aspect.

Uren PJ, Bahrami-Samani E, de Araujo PR, Vogel C, Qiao M, Burns SC, Smith AD, Penalva LO.

RNA Biol. 2016;13(4):400-11. doi: 10.1080/15476286.2015.1138030. Epub 2016 Jan 13.

18.

miR-124, -128, and -137 Orchestrate Neural Differentiation by Acting on Overlapping Gene Sets Containing a Highly Connected Transcription Factor Network.

Santos MC, Tegge AN, Correa BR, Mahesula S, Kohnke LQ, Qiao M, Ferreira MA, Kokovay E, Penalva LO.

Stem Cells. 2016 Jan;34(1):220-32. doi: 10.1002/stem.2204. Epub 2015 Sep 15.

19.

A Mouse Model of Targeted Musashi1 Expression in Whole Intestinal Epithelium Suggests Regulatory Roles in Cell Cycle and Stemness.

Cambuli FM, Correa BR, Rezza A, Burns SC, Qiao M, Uren PJ, Kress E, Boussouar A, Galante PA, Penalva LO, Plateroti M.

Stem Cells. 2015 Dec;33(12):3621-34. doi: 10.1002/stem.2202. Epub 2015 Sep 26.

20.

RNA-Binding Protein Musashi1 Is a Central Regulator of Adhesion Pathways in Glioblastoma.

Uren PJ, Vo DT, de Araujo PR, Pötschke R, Burns SC, Bahrami-Samani E, Qiao M, de Sousa Abreu R, Nakaya HI, Correa BR, Kühnöl C, Ule J, Martindale JL, Abdelmohsen K, Gorospe M, Smith AD, Penalva LO.

Mol Cell Biol. 2015 Sep 1;35(17):2965-78. doi: 10.1128/MCB.00410-15. Epub 2015 Jun 22.

21.

Computational challenges, tools, and resources for analyzing co- and post-transcriptional events in high throughput.

Bahrami-Samani E, Vo DT, de Araujo PR, Vogel C, Smith AD, Penalva LO, Uren PJ.

Wiley Interdiscip Rev RNA. 2015 May-Jun;6(3):291-310. doi: 10.1002/wrna.1274. Epub 2014 Dec 16. Review.

22.

Leveraging cross-link modification events in CLIP-seq for motif discovery.

Bahrami-Samani E, Penalva LO, Smith AD, Uren PJ.

Nucleic Acids Res. 2015 Jan;43(1):95-103. doi: 10.1093/nar/gku1288. Epub 2014 Dec 10.

23.

RNA binding protein HuR regulates the expression of ABCA1.

Ramírez CM, Lin CS, Abdelmohsen K, Goedeke L, Yoon JH, Madrigal-Matute J, Martin-Ventura JL, Vo DT, Uren PJ, Penalva LO, Gorospe M, Fernández-Hernando C.

J Lipid Res. 2014 Jun;55(6):1066-76. doi: 10.1194/jlr.M044925. Epub 2014 Apr 11.

24.

Genomic analyses reveal broad impact of miR-137 on genes associated with malignant transformation and neuronal differentiation in glioblastoma cells.

Tamim S, Vo DT, Uren PJ, Qiao M, Bindewald E, Kasprzak WK, Shapiro BA, Nakaya HI, Burns SC, Araujo PR, Nakano I, Radek AJ, Kuersten S, Smith AD, Penalva LO.

PLoS One. 2014 Jan 22;9(1):e85591. doi: 10.1371/journal.pone.0085591. eCollection 2014.

25.

WTAP is a novel oncogenic protein in acute myeloid leukemia.

Bansal H, Yihua Q, Iyer SP, Ganapathy S, Proia DA, Penalva LO, Uren PJ, Suresh U, Carew JS, Karnad AB, Weitman S, Tomlinson GE, Rao MK, Kornblau SM, Bansal S.

Leukemia. 2014 May;28(5):1171-4. doi: 10.1038/leu.2014.16. Epub 2014 Jan 13. No abstract available. Erratum in: Leukemia. 2014 Dec;28(12):2427. Proia, D [Corrected to Proia, D A].

26.

A compendium of RNA-binding motifs for decoding gene regulation.

Ray D, Kazan H, Cook KB, Weirauch MT, Najafabadi HS, Li X, Gueroussov S, Albu M, Zheng H, Yang A, Na H, Irimia M, Matzat LH, Dale RK, Smith SA, Yarosh CA, Kelly SM, Nabet B, Mecenas D, Li W, Laishram RS, Qiao M, Lipshitz HD, Piano F, Corbett AH, Carstens RP, Frey BJ, Anderson RA, Lynch KW, Penalva LO, Lei EP, Fraser AG, Blencowe BJ, Morris QD, Hughes TR.

Nature. 2013 Jul 11;499(7457):172-7. doi: 10.1038/nature12311.

27.

Musashi1 as a potential therapeutic target and diagnostic marker for lung cancer.

Wang XY, Yu H, Linnoila RI, Li L, Li D, Mo B, Okano H, Penalva LO, Glazer RI.

Oncotarget. 2013 May;4(5):739-50.

28.

Translation regulation gets its 'omics' moment.

Kuersten S, Radek A, Vogel C, Penalva LO.

Wiley Interdiscip Rev RNA. 2013 Nov-Dec;4(6):617-30. doi: 10.1002/wrna.1173. Epub 2013 May 15. Review.

29.

Site identification in high-throughput RNA-protein interaction data.

Uren PJ, Bahrami-Samani E, Burns SC, Qiao M, Karginov FV, Hodges E, Hannon GJ, Sanford JR, Penalva LO, Smith AD.

Bioinformatics. 2012 Dec 1;28(23):3013-20. doi: 10.1093/bioinformatics/bts569. Epub 2012 Sep 28.

30.

The RNA-binding protein Musashi1 affects medulloblastoma growth via a network of cancer-related genes and is an indicator of poor prognosis.

Vo DT, Subramaniam D, Remke M, Burton TL, Uren PJ, Gelfond JA, de Sousa Abreu R, Burns SC, Qiao M, Suresh U, Korshunov A, Dubuc AM, Northcott PA, Smith AD, Pfister SM, Taylor MD, Janga SC, Anant S, Vogel C, Penalva LO.

Am J Pathol. 2012 Nov;181(5):1762-72. doi: 10.1016/j.ajpath.2012.07.031. Epub 2012 Sep 14.

31.

Before It Gets Started: Regulating Translation at the 5' UTR.

Araujo PR, Yoon K, Ko D, Smith AD, Qiao M, Suresh U, Burns SC, Penalva LO.

Comp Funct Genomics. 2012;2012:475731. doi: 10.1155/2012/475731. Epub 2012 May 28.

32.

The oncogenic RNA-binding protein Musashi1 is regulated by HuR via mRNA translation and stability in glioblastoma cells.

Vo DT, Abdelmohsen K, Martindale JL, Qiao M, Tominaga K, Burton TL, Gelfond JA, Brenner AJ, Patel V, Trageser D, Scheffler B, Gorospe M, Penalva LO.

Mol Cancer Res. 2012 Jan;10(1):143-55. doi: 10.1158/1541-7786.MCR-11-0208.

33.

The RNA-Binding Protein Musashi1: A Major Player in Intestinal Epithelium Renewal and Colon Cancer Development.

Plateroti M, de Araujo PR, da Silva AE, Penalva LO.

Curr Colorectal Cancer Rep. 2012;8(4):290-297.

34.

Musashi1: an RBP with versatile functions in normal and cancer stem cells.

Glazer RI, Vo DT, Penalva LO.

Front Biosci (Landmark Ed). 2012 Jan 1;17:54-64. Review.

PMID:
22201732
35.

Genomic analyses of the RNA-binding protein Hu antigen R (HuR) identify a complex network of target genes and novel characteristics of its binding sites.

Uren PJ, Burns SC, Ruan J, Singh KK, Smith AD, Penalva LO.

J Biol Chem. 2011 Oct 28;286(43):37063-6. doi: 10.1074/jbc.C111.266882. Epub 2011 Sep 2.

36.

MicroRNA-16 and microRNA-424 regulate cell-autonomous angiogenic functions in endothelial cells via targeting vascular endothelial growth factor receptor-2 and fibroblast growth factor receptor-1.

Chamorro-Jorganes A, Araldi E, Penalva LO, Sandhu D, Fernández-Hernando C, Suárez Y.

Arterioscler Thromb Vasc Biol. 2011 Nov;31(11):2595-606. doi: 10.1161/ATVBAHA.111.236521.

37.

The oncogenic RNA-binding protein Musashi1 is regulated by tumor suppressor miRNAs.

Vo DT, Qiao M, Smith AD, Burns SC, Brenner AJ, Penalva LO.

RNA Biol. 2011 Sep-Oct;8(5):817-28. doi: 10.4161/rna.8.5.16041. Epub 2011 Sep 1.

PMID:
21881409
38.

miR-33a/b contribute to the regulation of fatty acid metabolism and insulin signaling.

Dávalos A, Goedeke L, Smibert P, Ramírez CM, Warrier NP, Andreo U, Cirera-Salinas D, Rayner K, Suresh U, Pastor-Pareja JC, Esplugues E, Fisher EA, Penalva LO, Moore KJ, Suárez Y, Lai EC, Fernández-Hernando C.

Proc Natl Acad Sci U S A. 2011 May 31;108(22):9232-7. doi: 10.1073/pnas.1102281108. Epub 2011 May 16.

39.

Two-tiered approach identifies a network of cancer and liver disease-related genes regulated by miR-122.

Boutz DR, Collins PJ, Suresh U, Lu M, Ramírez CM, Fernández-Hernando C, Huang Y, Abreu Rde S, Le SY, Shapiro BA, Liu AM, Luk JM, Aldred SF, Trinklein ND, Marcotte EM, Penalva LO.

J Biol Chem. 2011 May 20;286(20):18066-78. doi: 10.1074/jbc.M110.196451. Epub 2011 Mar 14.

40.

LATENT RANK CHANGE DETECTION FOR ANALYSIS OF SPLICE-JUNCTION MICROARRAYS WITH NONLINEAR EFFECTS.

Gelfond J, Zarzabal LA, Burton T, Burns S, Sogayar M, Penalva LO.

Ann Appl Stat. 2011;5(1):364-380.

41.

RIP-Chip analysis: RNA-Binding Protein Immunoprecipitation-Microarray (Chip) Profiling.

Jain R, Devine T, George AD, Chittur SV, Baroni TE, Penalva LO, Tenenbaum SA.

Methods Mol Biol. 2011;703:247-63. doi: 10.1007/978-1-59745-248-9_17.

PMID:
21125495
42.

Sequence signatures and mRNA concentration can explain two-thirds of protein abundance variation in a human cell line.

Vogel C, Abreu Rde S, Ko D, Le SY, Shapiro BA, Burns SC, Sandhu D, Boutz DR, Marcotte EM, Penalva LO.

Mol Syst Biol. 2010 Aug 24;6:400. doi: 10.1038/msb.2010.59.

43.

Musashi1 regulates breast tumor cell proliferation and is a prognostic indicator of poor survival.

Wang XY, Penalva LO, Yuan H, Linnoila RI, Lu J, Okano H, Glazer RI.

Mol Cancer. 2010 Aug 21;9:221. doi: 10.1186/1476-4598-9-221.

44.

Global signatures of protein and mRNA expression levels.

de Sousa Abreu R, Penalva LO, Marcotte EM, Vogel C.

Mol Biosyst. 2009 Dec;5(12):1512-26. doi: 10.1039/b908315d. Epub 2009 Oct 1. Review.

45.

Mining gene functional networks to improve mass-spectrometry-based protein identification.

Ramakrishnan SR, Vogel C, Kwon T, Penalva LO, Marcotte EM, Miranker DP.

Bioinformatics. 2009 Nov 15;25(22):2955-61. doi: 10.1093/bioinformatics/btp461. Epub 2009 Jul 24.

46.

A comprehensive in silico expression analysis of RNA binding proteins in normal and tumor tissue: Identification of potential players in tumor formation.

Galante PA, Sandhu D, de Sousa Abreu R, Gradassi M, Slager N, Vogel C, de Souza SJ, Penalva LO.

RNA Biol. 2009 Sep-Oct;6(4):426-33. Epub 2009 Sep 24.

47.

Integrating shotgun proteomics and mRNA expression data to improve protein identification.

Ramakrishnan SR, Vogel C, Prince JT, Li Z, Penalva LO, Myers M, Marcotte EM, Miranker DP, Wang R.

Bioinformatics. 2009 Jun 1;25(11):1397-403. doi: 10.1093/bioinformatics/btp168. Epub 2009 Mar 24.

48.

Genomic analyses of musashi1 downstream targets show a strong association with cancer-related processes.

de Sousa Abreu R, Sanchez-Diaz PC, Vogel C, Burns SC, Ko D, Burton TL, Vo DT, Chennasamudaram S, Le SY, Shapiro BA, Penalva LO.

J Biol Chem. 2009 May 1;284(18):12125-35. doi: 10.1074/jbc.M809605200. Epub 2009 Mar 3.

49.

Over-represented sequences located on 3' UTRs are potentially involved in regulatory functions.

Yoon K, Ko D, Doderer M, Livi CB, Penalva LO.

RNA Biol. 2008 Oct-Dec;5(4):255-62. Epub 2008 Oct 3.

50.

Musashi1 modulates cell proliferation genes in the medulloblastoma cell line Daoy.

Sanchez-Diaz PC, Burton TL, Burns SC, Hung JY, Penalva LO.

BMC Cancer. 2008 Sep 30;8:280. doi: 10.1186/1471-2407-8-280.

Supplemental Content

Loading ...
Support Center