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Items: 1 to 50 of 51

1.

The quantitative neuroradiology initiative framework: application to dementia.

Goodkin O, Pemberton H, Vos SB, Prados F, Sudre CH, Moggridge J, Cardoso MJ, Ourselin S, Bisdas S, White M, Yousry T, Thornton J, Barkhof F.

Br J Radiol. 2019 Sep;92(1101):20190365. doi: 10.1259/bjr.20190365. Epub 2019 Aug 1. Review.

PMID:
31368776
2.

An examination of orbitofrontal sulcogyral morphology in obsessive-compulsive disorder.

Delahoy R, Bartholomeusz CF, Pemberton H, Alonso P, Pujol J, Cardoner N, Menchon JM, Soriano-Mas C, Harrison BJ.

Psychiatry Res Neuroimaging. 2019 Apr 30;286:18-23. doi: 10.1016/j.pscychresns.2019.02.004. Epub 2019 Feb 22.

PMID:
30852254
3.

Author Correction: Chemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAness.

Holme H, Gulati A, Brough R, Fleuren EDG, Bajrami I, Campbell J, Chong IY, Costa-Cabral S, Elliott R, Fenton T, Frankum J, Jones SE, Menon M, Miller R, Pemberton HN, Postel-Vinay S, Rafiq R, Selfe JL, von Kriegsheim A, Munoz AG, Rodriguez J, Shipley J, van der Graaf WTA, Williamson CT, Ryan CJ, Pettitt S, Ashworth A, Strauss SJ, Lord CJ.

Sci Rep. 2018 Aug 21;8(1):12771. doi: 10.1038/s41598-018-30922-8.

4.

Chemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAness.

Holme H, Gulati A, Brough R, Fleuren EDG, Bajrami I, Campbell J, Chong IY, Costa-Cabral S, Elliott R, Fenton T, Frankum J, Jones SE, Menon M, Miller R, Pemberton HN, Postel-Vinay S, Rafiq R, Selfe JL, von Kriegsheim A, Munoz AG, Rodriguez J, Shipley J, van der Graaf WTA, Williamson CT, Ryan CJ, Pettitt S, Ashworth A, Strauss SJ, Lord CJ.

Sci Rep. 2018 Jul 13;8(1):10614. doi: 10.1038/s41598-018-29043-z. Erratum in: Sci Rep. 2018 Aug 21;8(1):12771.

5.

Functional diversity and cooperativity between subclonal populations of pediatric glioblastoma and diffuse intrinsic pontine glioma cells.

Vinci M, Burford A, Molinari V, Kessler K, Popov S, Clarke M, Taylor KR, Pemberton HN, Lord CJ, Gutteridge A, Forshew T, Carvalho D, Marshall LV, Qin EY, Ingram WJ, Moore AS, Ng HK, Trabelsi S, H'mida-Ben Brahim D, Entz-Werle N, Zacharoulis S, Vaidya S, Mandeville HC, Bridges LR, Martin AJ, Al-Sarraj S, Chandler C, Sunol M, Mora J, de Torres C, Cruz O, Carcaboso AM, Monje M, Mackay A, Jones C.

Nat Med. 2018 Aug;24(8):1204-1215. doi: 10.1038/s41591-018-0086-7. Epub 2018 Jul 2.

6.

Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance.

Pettitt SJ, Krastev DB, Brandsma I, Dréan A, Song F, Aleksandrov R, Harrell MI, Menon M, Brough R, Campbell J, Frankum J, Ranes M, Pemberton HN, Rafiq R, Fenwick K, Swain A, Guettler S, Lee JM, Swisher EM, Stoynov S, Yusa K, Ashworth A, Lord CJ.

Nat Commun. 2018 May 10;9(1):1849. doi: 10.1038/s41467-018-03917-2.

7.

E-Cadherin/ROS1 Inhibitor Synthetic Lethality in Breast Cancer.

Bajrami I, Marlow R, van de Ven M, Brough R, Pemberton HN, Frankum J, Song F, Rafiq R, Konde A, Krastev DB, Menon M, Campbell J, Gulati A, Kumar R, Pettitt SJ, Gurden MD, Cardenosa ML, Chong I, Gazinska P, Wallberg F, Sawyer EJ, Martin LA, Dowsett M, Linardopoulos S, Natrajan R, Ryan CJ, Derksen PWB, Jonkers J, Tutt ANJ, Ashworth A, Lord CJ.

Cancer Discov. 2018 Apr;8(4):498-515. doi: 10.1158/2159-8290.CD-17-0603.

8.

Serum neurofilament light in familial Alzheimer disease: A marker of early neurodegeneration.

Weston PSJ, Poole T, Ryan NS, Nair A, Liang Y, Macpherson K, Druyeh R, Malone IB, Ahsan RL, Pemberton H, Klimova J, Mead S, Blennow K, Rossor MN, Schott JM, Zetterberg H, Fox NC.

Neurology. 2017 Nov 21;89(21):2167-2175. doi: 10.1212/WNL.0000000000004667. Epub 2017 Oct 25.

9.

ATR Is a Therapeutic Target in Synovial Sarcoma.

Jones SE, Fleuren EDG, Frankum J, Konde A, Williamson CT, Krastev DB, Pemberton HN, Campbell J, Gulati A, Elliott R, Menon M, Selfe JL, Brough R, Pettitt SJ, Niedzwiedz W, van der Graaf WTA, Shipley J, Ashworth A, Lord CJ.

Cancer Res. 2017 Dec 15;77(24):7014-7026. doi: 10.1158/0008-5472.CAN-17-2056. Epub 2017 Oct 16.

10.

Initiation of a Multidisciplinary, Rapid Response Team to Massive and Submassive Pulmonary Embolism.

Carroll BJ, Pemberton H, Bauer KA, Chu LM, Weinstein JL, Levarge BL, Pinto DS.

Am J Cardiol. 2017 Oct 15;120(8):1393-1398. doi: 10.1016/j.amjcard.2017.07.033. Epub 2017 Jul 26.

PMID:
28807405
11.

Motor speech signature of behavioral variant frontotemporal dementia: Refining the phenotype.

Vogel AP, Poole ML, Pemberton H, Caverlé MWJ, Boonstra FMC, Low E, Darby D, Brodtmann A.

Neurology. 2017 Aug 22;89(8):837-844. doi: 10.1212/WNL.0000000000004248. Epub 2017 Jul 21.

PMID:
28733335
12.

Modeling Therapy Resistance in BRCA1/2-Mutant Cancers.

Dréan A, Williamson CT, Brough R, Brandsma I, Menon M, Konde A, Garcia-Murillas I, Pemberton HN, Frankum J, Rafiq R, Badham N, Campbell J, Gulati A, Turner NC, Pettitt SJ, Ashworth A, Lord CJ.

Mol Cancer Ther. 2017 Sep;16(9):2022-2034. doi: 10.1158/1535-7163.MCT-17-0098. Epub 2017 Jun 15.

13.

Elevated APOBEC3B expression drives a kataegic-like mutation signature and replication stress-related therapeutic vulnerabilities in p53-defective cells.

Nikkilä J, Kumar R, Campbell J, Brandsma I, Pemberton HN, Wallberg F, Nagy K, Scheer I, Vertessy BG, Serebrenik AA, Monni V, Harris RS, Pettitt SJ, Ashworth A, Lord CJ.

Br J Cancer. 2017 Jun 27;117(1):113-123. doi: 10.1038/bjc.2017.133. Epub 2017 May 23.

14.

Genome-wide barcoded transposon screen for cancer drug sensitivity in haploid mouse embryonic stem cells.

Pettitt SJ, Krastev DB, Pemberton HN, Fontebasso Y, Frankum J, Rehman FL, Brough R, Song F, Bajrami I, Rafiq R, Wallberg F, Kozarewa I, Fenwick K, Armisen-Garrido J, Swain A, Gulati A, Campbell J, Ashworth A, Lord CJ.

Sci Data. 2017 Mar 1;4:170020. doi: 10.1038/sdata.2017.20.

15.

ATR inhibitors as a synthetic lethal therapy for tumours deficient in ARID1A.

Williamson CT, Miller R, Pemberton HN, Jones SE, Campbell J, Konde A, Badham N, Rafiq R, Brough R, Gulati A, Ryan CJ, Francis J, Vermulen PB, Reynolds AR, Reaper PM, Pollard JR, Ashworth A, Lord CJ.

Nat Commun. 2016 Dec 13;7:13837. doi: 10.1038/ncomms13837.

16.

Synthetic Lethal Targeting of ARID1A-Mutant Ovarian Clear Cell Tumors with Dasatinib.

Miller RE, Brough R, Bajrami I, Williamson CT, McDade S, Campbell J, Kigozi A, Rafiq R, Pemberton H, Natrajan R, Joel J, Astley H, Mahoney C, Moore JD, Torrance C, Gordan JD, Webber JT, Levin RS, Shokat KM, Bandyopadhyay S, Lord CJ, Ashworth A.

Mol Cancer Ther. 2016 Jul;15(7):1472-84. doi: 10.1158/1535-7163.MCT-15-0554. Epub 2016 Jun 30.

17.

RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress.

Kanu N, Zhang T, Burrell RA, Chakraborty A, Cronshaw J, DaCosta C, Grönroos E, Pemberton HN, Anderton E, Gonzalez L, Sabbioneda S, Ulrich HD, Swanton C, Behrens A.

Oncogene. 2016 Jul 28;35(30):4020. doi: 10.1038/onc.2015.500. Epub 2016 Jun 27. No abstract available.

PMID:
27345393
18.

Diagnostic Distortions: A Case Report of Progressive Apraxia of Speech.

Brodtmann A, Pemberton H, Darby D, Vogel AP.

J Alzheimers Dis. 2016 Apr 19;53(1):79-83. doi: 10.3233/JAD-160069.

PMID:
27104903
19.

Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines.

Campbell J, Ryan CJ, Brough R, Bajrami I, Pemberton HN, Chong IY, Costa-Cabral S, Frankum J, Gulati A, Holme H, Miller R, Postel-Vinay S, Rafiq R, Wei W, Williamson CT, Quigley DA, Tym J, Al-Lazikani B, Fenton T, Natrajan R, Strauss SJ, Ashworth A, Lord CJ.

Cell Rep. 2016 Mar 15;14(10):2490-501. doi: 10.1016/j.celrep.2016.02.023. Epub 2016 Mar 3.

20.

RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress.

Kanu N, Zhang T, Burrell RA, Chakraborty A, Cronshaw J, DaCosta C, Grönroos E, Pemberton HN, Anderton E, Gonzalez L, Sabbioneda S, Ulrich HD, Swanton C, Behrens A.

Oncogene. 2016 Jul 28;35(30):4009-19. doi: 10.1038/onc.2015.427. Epub 2015 Nov 9. Erratum in: Oncogene. 2016 Jul 28;35(30):4020.

21.

DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer.

Mateo J, Carreira S, Sandhu S, Miranda S, Mossop H, Perez-Lopez R, Nava Rodrigues D, Robinson D, Omlin A, Tunariu N, Boysen G, Porta N, Flohr P, Gillman A, Figueiredo I, Paulding C, Seed G, Jain S, Ralph C, Protheroe A, Hussain S, Jones R, Elliott T, McGovern U, Bianchini D, Goodall J, Zafeiriou Z, Williamson CT, Ferraldeschi R, Riisnaes R, Ebbs B, Fowler G, Roda D, Yuan W, Wu YM, Cao X, Brough R, Pemberton H, A'Hern R, Swain A, Kunju LP, Eeles R, Attard G, Lord CJ, Ashworth A, Rubin MA, Knudsen KE, Feng FY, Chinnaiyan AM, Hall E, de Bono JS.

N Engl J Med. 2015 Oct 29;373(18):1697-708. doi: 10.1056/NEJMoa1506859.

22.

Progesterone and allopregnanolone improves stroke outcome in male mice via distinct mechanisms but neither promotes neurogenesis.

Lee RJ, Kim JK, Chao D, Kuo L, Mally A, McClean ME, Pemberton HE, Wilmington AR, Wong J, Murphy SP.

J Neurochem. 2015 Jan;132(1):32-7. doi: 10.1111/jnc.12990. Epub 2014 Dec 2.

23.

The nuclear receptor NR2E1/TLX controls senescence.

O'Loghlen A, Martin N, Krusche B, Pemberton H, Alonso MM, Chandler H, Brookes S, Parrinello S, Peters G, Gil J.

Oncogene. 2015 Jul 30;34(31):4069-4077. doi: 10.1038/onc.2014.335. Epub 2014 Oct 20.

24.

Genome-wide co-localization of Polycomb orthologs and their effects on gene expression in human fibroblasts.

Pemberton H, Anderton E, Patel H, Brookes S, Chandler H, Palermo R, Stock J, Rodriguez-Niedenführ M, Racek T, de Breed L, Stewart A, Matthews N, Peters G.

Genome Biol. 2014 Feb 3;15(2):R23. doi: 10.1186/gb-2014-15-2-r23.

25.

MS-275, a class I histone deacetylase inhibitor, protects the p53-deficient mouse against ischemic injury.

Murphy SP, Lee RJ, McClean ME, Pemberton HE, Uo T, Morrison RS, Bastian C, Baltan S.

J Neurochem. 2014 May;129(3):509-15. doi: 10.1111/jnc.12498. Epub 2013 Nov 6.

26.

Breast cancer intratumor genetic heterogeneity: causes and implications.

Ng CK, Pemberton HN, Reis-Filho JS.

Expert Rev Anticancer Ther. 2012 Aug;12(8):1021-32. doi: 10.1586/era.12.85. Review.

PMID:
23030222
27.

MicroRNA regulation of Cbx7 mediates a switch of Polycomb orthologs during ESC differentiation.

O'Loghlen A, Muñoz-Cabello AM, Gaspar-Maia A, Wu HA, Banito A, Kunowska N, Racek T, Pemberton HN, Beolchi P, Lavial F, Masui O, Vermeulen M, Carroll T, Graumann J, Heard E, Dillon N, Azuara V, Snijders AP, Peters G, Bernstein E, Gil J.

Cell Stem Cell. 2012 Jan 6;10(1):33-46. doi: 10.1016/j.stem.2011.12.004.

28.

Modified cell cycle status in a mouse model of altered neuronal vulnerability (slow Wallerian degeneration; Wlds).

Wishart TM, Pemberton HN, James SR, McCabe CJ, Gillingwater TH.

Genome Biol. 2008;9(6):R101. doi: 10.1186/gb-2008-9-6-r101. Epub 2008 Jun 20.

29.

Separase, securin and Rad21 in neural cell growth.

Pemberton HN, Franklyn JA, Boelaert K, Chan SY, Kim DS, Kim C, Cheng SY, Kilby MD, McCabe CJ.

J Cell Physiol. 2007 Oct;213(1):45-53.

PMID:
17450531
30.

Securin induces genetic instability in colorectal cancer by inhibiting double-stranded DNA repair activity.

Kim DS, Franklyn JA, Smith VE, Stratford AL, Pemberton HN, Warfield A, Watkinson JC, Ishmail T, Wakelam MJ, McCabe CJ.

Carcinogenesis. 2007 Mar;28(3):749-59. Epub 2006 Oct 27.

PMID:
17071631
31.

Monocarboxylate transporter 8 expression in the human placenta: the effects of severe intrauterine growth restriction.

Chan SY, Franklyn JA, Pemberton HN, Bulmer JN, Visser TJ, McCabe CJ, Kilby MD.

J Endocrinol. 2006 Jun;189(3):465-71.

32.

Thyroid hormones and fetal brain development.

Pemberton HN, Franklyn JA, Kilby MD.

Minerva Ginecol. 2005 Aug;57(4):367-78. Review.

PMID:
16170282
33.

Pituitary tumour transforming gene (PTTG) induces genetic instability in thyroid cells.

Kim D, Pemberton H, Stratford AL, Buelaert K, Watkinson JC, Lopes V, Franklyn JA, McCabe CJ.

Oncogene. 2005 Jul 14;24(30):4861-6.

PMID:
15897900
34.

Bifunctional role for VEGF-induced heme oxygenase-1 in vivo: induction of angiogenesis and inhibition of leukocytic infiltration.

Bussolati B, Ahmed A, Pemberton H, Landis RC, Di Carlo F, Haskard DO, Mason JC.

Blood. 2004 Feb 1;103(3):761-6. Epub 2003 Oct 2.

PMID:
14525760
35.

Pneumatosis cystoides intestinalis involving left portion of colon; report of four cases diagnosed at sigmoidoscopy.

SMITH WG, ANDERSON MJ Jr, PEMBERTON HW.

Gastroenterology. 1958 Nov;35(5):528-33. No abstract available.

PMID:
13598044
36.

Pneumatosis cystoides intestinalis diagnosed sigmoidoscopically; report of case and review of literature.

PEMBERTON HW, SMITH WG, HOLMAN CB.

Am J Surg. 1957 Sep;94(3):472-7. No abstract available.

PMID:
13458614
37.

The clinical aspects of obesity.

PEMBERTON HS.

Practitioner. 1955 Jul;175(1045):5-11. No abstract available.

PMID:
13245581
38.

Glycogen storage in the liver in diabetes mellitus.

EVANS RW, LITTLER TR, PEMBERTON HS.

J Clin Pathol. 1955 May;8(2):110-3. No abstract available.

39.

Method of preventing insulin atrophy.

FOX JG, McCONNELL RB, PEMBERTON HS, WATSON DC.

Br Med J. 1953 Nov 28;2(4847):1202-3. No abstract available.

40.

Intra-arterial injections in the treatment of peripheral vascular disease.

EDWARDS JW, JONES NB, MCCONNELL RB, PEMBERTON HS, WATSON DC.

Br Med J. 1952 Oct 11;2(4788):808-11. No abstract available.

41.

Iontophoresis in the treatment of peripheral vascular disease.

PEMBERTON HS, WATSON DC.

Br Med J. 1949 Sep 17;2(4628):633. No abstract available.

42.

Intestinal actinomycosis treated with streptomycin.

PEMBERTON HS, HUNTER WR.

Lancet. 1949 Jun 25;1(6565):1094. No abstract available.

PMID:
18153585
43.

Stevens-Johnson syndrome.

HOTSTON RD, PEMBERTON HS.

Lancet. 1947 Apr 12;1(6450):499. No abstract available.

PMID:
20294834
44.

Thiouracil in the Treatment of Thyrotoxicosis.

Grainger A, Gregson DA, Pemberton HS.

Br Med J. 1945 Sep 15;2(4419):343-5. No abstract available.

45.

The Clinic Control of Diabetes Mellitus.

Pemberton HS.

Postgrad Med J. 1932 Aug;8(82):281-5. No abstract available.

46.

ARTHRITIS DEFORMANS: OBSERVATIONS ON ITS ETIOLOGY AND TREATMENT: (Preliminary Communication.).

Ashcroft LS, Cunningham L, McMurray TP, Pemberton HS.

Br Med J. 1925 Jul 4;2(3366):13. No abstract available.

47.

HYPOGLYCAEMIA: WITH NOTES ON TWO CASES.

Pemberton HS.

Br Med J. 1925 May 30;1(3361):1004-5. No abstract available.

48.

A SIMPLE DIET TABLE.

Pemberton HS.

Br Med J. 1923 Apr 21;1(3251):679-80. No abstract available.

49.

THE DIAGNOSTIC VALUE OF GASTRIC FRACTIONAL TEST MEALS.

Pemberton HS.

Br Med J. 1922 Jul 1;2(3209):7-8. No abstract available.

50.

PECULIAR ELECTRICAL PHENOMENA.

Pemberton H Jr.

Science. 1909 Jan 22;29(734):143. No abstract available.

PMID:
17730303

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