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Items: 49

1.

ProBNP That Is Not Glycosylated at Threonine 71 Is Decreased With Obesity in Patients with Heart Failure.

Lewis LK, Raudsepp SD, Prickett TCR, Yandle TG, Doughty RN, Frampton CM, Pemberton CJ, Richards AM.

Clin Chem. 2019 May 15. pii: clinchem.2019.302547. doi: 10.1373/clinchem.2019.302547. [Epub ahead of print]

PMID:
31092393
2.

Validity of a Novel Point-of-Care Troponin Assay for Single-Test Rule-Out of Acute Myocardial Infarction.

Pickering JW, Young JM, George PM, Watson AS, Aldous SJ, Troughton RW, Pemberton CJ, Richards AM, Cullen LA, Than MP.

JAMA Cardiol. 2018 Nov 1;3(11):1108-1112. doi: 10.1001/jamacardio.2018.3368.

PMID:
30347004
3.

Plasma levels of soluble VEGF receptor isoforms, circulating pterins and VEGF system SNPs as prognostic biomarkers in patients with acute coronary syndromes.

Marks ECA, Wilkinson TM, Frampton CM, Skelton L, Pilbrow AP, Yandle TG, Pemberton CJ, Doughty RN, Whalley GA, Ellis CJ, Troughton RW, Owen MC, Pattinson NR, Cameron VA, Richards AM, Gieseg SP, Palmer BR.

BMC Cardiovasc Disord. 2018 Aug 15;18(1):169. doi: 10.1186/s12872-018-0894-1.

4.

Detectable High-Sensitivity Cardiac Troponin within the Population Reference Interval Conveys High 5-Year Cardiovascular Risk: An Observational Study.

Than MP, Aldous SJ, Troughton RW, Pemberton CJ, Richards AM, Frampton CMA, Florkowski CM, George PM, Bailey S, Young JM, Cullen L, Greenslade JH, Parsonage WA, Everett BM, Peacock WF, Jaffe AS, Pickering JW.

Clin Chem. 2018 Jul;64(7):1044-1053. doi: 10.1373/clinchem.2017.285700. Epub 2018 May 14.

PMID:
29760219
5.

The heart regulates the endocrine response to heart failure: cardiac contribution to circulating neprilysin.

Arrigo M, Vodovar N, Nougué H, Sadoune M, Pemberton CJ, Ballan P, Ludes PO, Gendron N, Carpentier A, Cholley B, Bizouarn P, Cohen-Solal A, Singh JP, Szymonifka J, Latremouille C, Samuel JL, Launay JM, Pottecher J, Richards AM, Truong QA, Smadja DM, Mebazaa A.

Eur Heart J. 2018 May 21;39(20):1794-1798. doi: 10.1093/eurheartj/ehx679.

PMID:
29244074
6.

Mortality and acute exacerbation of COPD: a pilot study on the influence of myocardial injury.

Laribi S, Pemberton CJ, Kirwan L, Nouira S, Turkdogan K, Yilmaz MB, Troughton RW, Gayat E, Rivas-Lasarte M, Sadoune M, Sabti Z, Hansconrad E, Motiejunaite J, Plaisance P, Beshiri A, Chen W, Collet C, FitzGerald JM, Mueller C, Launay JM, Richards M, Mebazaa A; GREAT (Global Research on Acute Conditions Team) Network.

Eur Respir J. 2017 Jun 29;49(6). pii: 1700096. doi: 10.1183/13993003.00096-2017. Print 2017 Jun. No abstract available.

7.

Release kinetics of high-sensitivity cardiac troponins I and T and troponin T upstream open reading frame peptide (TnTuORF) in clinically induced acute myocardial infarction.

Liebetrau C, Gaede L, Wolter JS, Homann J, Meyer A, Dörr O, Nef HM, Troidl C, Hamm CW, Möllmann H, Richards AM, Pemberton CJ.

Biomarkers. 2017 May - Jun;22(3-4):304-310. doi: 10.1080/1354750X.2016.1252965. Epub 2016 Nov 22.

PMID:
27775442
8.

Superior performance of N-terminal pro brain natriuretic peptide for diagnosis of acute decompensated heart failure in an Asian compared with a Western setting.

Ibrahim I, Kuan WS, Frampton C, Troughton R, Liew OW, Chong JP, Chan SP, Tan LL, Lin WQ, Pemberton CJ, Ooi SB, Richards AM.

Eur J Heart Fail. 2017 Feb;19(2):209-217. doi: 10.1002/ejhf.612. Epub 2016 Sep 13.

9.

B-type natriuretic peptide signal peptide (BNPsp) in patients presenting with chest pain.

Pemberton CJ, Frampton CM, Aldous S, Bailey M, Young J, Troughton R, Than M, Richards M.

Clin Biochem. 2016 Jun;49(9):645-650. doi: 10.1016/j.clinbiochem.2016.02.015. Epub 2016 Mar 9.

PMID:
26968107
10.

CNP Signal Peptide in Patients with Cardiovascular Disease.

Lee J, Than M, Aldous S, Troughton R, Richards M, Pemberton CJ.

Front Cardiovasc Med. 2015 Jun 15;2:28. doi: 10.3389/fcvm.2015.00028. eCollection 2015.

11.

Reference Values and Release Kinetics of B-Type Natriuretic Peptide Signal Peptide in Patients with Acute Myocardial Infarction.

Liebetrau C, Gaede L, Dörr O, Blumenstein J, Rosenburg S, Hoffmann J, Troidl C, Hamm CW, Nef HM, Möllmann H, Richards AM, Pemberton CJ.

Clin Chem. 2015 Dec;61(12):1532-9. doi: 10.1373/clinchem.2015.244327. Epub 2015 Oct 27.

12.

A novel troponin T peptide in humans: Assay, biochemistry and preliminary findings in acute coronary syndromes.

Lee J, Young J, Frampton CM, Aldous S, Troughton RW, Than M, Richards AM, Pemberton CJ.

Int J Cardiol. 2015;190:68-74. doi: 10.1016/j.ijcard.2015.04.145. Epub 2015 Apr 17.

PMID:
25918054
13.

Accelerated diagnostic protocol using high-sensitivity cardiac troponin T in acute chest pain patients.

Meller B, Cullen L, Parsonage WA, Greenslade JH, Aldous S, Reichlin T, Wildi K, Twerenbold R, Jaeger C, Hillinger P, Haaf P, Puelacher C, Kern V, Rentsch K, Stallone F, Rubini Gimenez M, Ballarino P, Bassetti S, Walukiewicz A, Troughton R, Pemberton CJ, Richards AM, Chu K, Reid CM, Than M, Mueller C.

Int J Cardiol. 2015 Apr 1;184:208-15. doi: 10.1016/j.ijcard.2015.02.006. Epub 2015 Feb 11.

PMID:
25710784
14.

Signal peptides: new markers in cardiovascular disease?

Pemberton CJ.

Biomark Med. 2014;8(8):1013-9. doi: 10.2217/bmm.14.64. Review.

PMID:
25343673
15.

C-type natriuretic peptide (CNP) signal peptide fragments are present in the human circulation.

Pemberton CJ, Siriwardena M, Kleffmann T, Richards AM.

Biochem Biophys Res Commun. 2014 Jul 4;449(3):301-6. doi: 10.1016/j.bbrc.2014.05.020. Epub 2014 May 15.

PMID:
24845564
16.

B-type natriuretic peptide forms within the heart, coronary sinus, and peripheral circulation in humans: evidence for degradation before secretion.

Mahagamasekera PG, Ruygrok PN, Palmer SC, Richards AM, Ansell GS, Nicholls MG, Pemberton CJ, Lewis LK, Yandle TG.

Clin Chem. 2014 Mar;60(3):549-58. doi: 10.1373/clinchem.2013.210435. Epub 2014 Jan 10.

17.

Comparison of high sensitivity troponin T and I assays in the diagnosis of non-ST elevation acute myocardial infarction in emergency patients with chest pain.

Cullen L, Aldous S, Than M, Greenslade JH, Tate JR, George PM, Hammett CJ, Richards AM, Ungerer JP, Troughton RW, Brown AF, Flaws DF, Lamanna A, Pemberton CJ, Florkowski C, Pretorius CJ, Chu K, Parsonage WA.

Clin Biochem. 2014 Apr;47(6):321-6. doi: 10.1016/j.clinbiochem.2013.11.019. Epub 2013 Dec 5.

PMID:
24316100
18.

Validation of the Vancouver Chest Pain Rule using troponin as the only biomarker: a prospective cohort study.

Greenslade JH, Cullen L, Than M, Aldous S, Chu K, Brown AF, Richards AM, Pemberton CJ, George P, Parsonage WA.

Am J Emerg Med. 2013 Jul;31(7):1103-7. doi: 10.1016/j.ajem.2013.04.016. Epub 2013 May 20.

PMID:
23702078
19.

Validation of high-sensitivity troponin I in a 2-hour diagnostic strategy to assess 30-day outcomes in emergency department patients with possible acute coronary syndrome.

Cullen L, Mueller C, Parsonage WA, Wildi K, Greenslade JH, Twerenbold R, Aldous S, Meller B, Tate JR, Reichlin T, Hammett CJ, Zellweger C, Ungerer JPJ, Rubini Gimenez M, Troughton R, Murray K, Brown AFT, Mueller M, George P, Mosimann T, Flaws DF, Reiter M, Lamanna A, Haaf P, Pemberton CJ, Richards AM, Chu K, Reid CM, Peacock WF, Jaffe AS, Florkowski C, Deely JM, Than M.

J Am Coll Cardiol. 2013 Oct 1;62(14):1242-1249. doi: 10.1016/j.jacc.2013.02.078. Epub 2013 Apr 10.

20.

Cardiac biomarker responses to dobutamine stress echocardiography in healthy volunteers and patients with coronary artery disease.

Siriwardena M, Campbell V, Richards AM, Pemberton CJ.

Clin Chem. 2012 Oct;58(10):1492-4. Epub 2012 Aug 15. No abstract available.

21.

Oxidative stress rather than triglyceride accumulation is a determinant of mitochondrial dysfunction in in vitro models of hepatic cellular steatosis.

Lockman KA, Baren JP, Pemberton CJ, Baghdadi H, Burgess KE, Plevris-Papaioannou N, Lee P, Howie F, Beckett G, Pryde A, Jaap AJ, Hayes PC, Filippi C, Plevris JN.

Liver Int. 2012 Aug;32(7):1079-92. doi: 10.1111/j.1478-3231.2012.02775.x. Epub 2012 Mar 19.

PMID:
22429485
22.

First identification of circulating prepro-A-type natriuretic peptide (preproANP) signal peptide fragments in humans: initial assessment as cardiovascular biomarkers.

Pemberton CJ, Siriwardena M, Kleffmann T, Ruygrok P, Palmer SC, Yandle TG, Richards AM.

Clin Chem. 2012 Apr;58(4):757-67. doi: 10.1373/clinchem.2011.176990. Epub 2012 Jan 30.

23.

B-type natriuretic peptides: looking to the future.

Troughton RW, Lewis LK, Yandle TG, Pemberton CJ, Nicholls MG.

Ann Med. 2011 May;43(3):188-97. doi: 10.3109/07853890.2010.526630. Epub 2010 Oct 21. Review.

PMID:
20961274
24.

B-type natriuretic peptide signal peptide circulates in human blood: evaluation as a potential biomarker of cardiac ischemia.

Siriwardena M, Kleffmann T, Ruygrok P, Cameron VA, Yandle TG, Nicholls MG, Richards AM, Pemberton CJ.

Circulation. 2010 Jul 20;122(3):255-64. doi: 10.1161/CIRCULATIONAHA.109.909937. Epub 2010 Jul 6.

PMID:
20606123
25.

Regional vascular response to ProAngiotensin-12 (PA12) through the rat arterial system.

Prosser HC, Richards AM, Forster ME, Pemberton CJ.

Peptides. 2010 Aug;31(8):1540-5. doi: 10.1016/j.peptides.2010.05.009. Epub 2010 May 20.

PMID:
20493224
26.

Metformin increases plasma ghrelin in Type 2 diabetes.

Doogue MP, Begg EJ, Moore MP, Lunt H, Pemberton CJ, Zhang M.

Br J Clin Pharmacol. 2009 Dec;68(6):875-82. doi: 10.1111/j.1365-2125.2009.03372.x.

27.

Cardiac chymase converts rat proAngiotensin-12 (PA12) to angiotensin II: effects of PA12 upon cardiac haemodynamics.

Prosser HC, Forster ME, Richards AM, Pemberton CJ.

Cardiovasc Res. 2009 Apr 1;82(1):40-50. doi: 10.1093/cvr/cvp003. Epub 2009 Jan 15.

PMID:
19147651
28.

Leptin-induced cardiac hypertrophy: RhoAing a lipid raft down a protective p38 MAPK signalling stream?

Pemberton CJ.

Cardiovasc Res. 2008 Jan;77(1):4-5. Epub 2007 Oct 30. No abstract available.

PMID:
18006446
29.

Biochemistry of ghrelin precursor peptides.

Pemberton CJ, Richards AM.

Vitam Horm. 2008;77:13-30. Review.

PMID:
17983851
30.

Direct cardiac actions of erythropoietin (EPO): effects on cardiac contractility, BNP secretion and ischaemia/reperfusion injury.

Piuhola J, Kerkelä R, Keenan JI, Hampton MB, Richards AM, Pemberton CJ.

Clin Sci (Lond). 2008 Feb;114(4):293-304.

PMID:
17919123
31.

Urotensin II and urotensin II-related peptide (URP) in cardiac ischemia-reperfusion injury.

Prosser HC, Forster ME, Richards AM, Pemberton CJ.

Peptides. 2008 May;29(5):770-7. Epub 2007 Aug 21.

PMID:
17900760
32.

Hypertension, cardiotrophin-1 and gp130: three points to heart failure?

Pemberton CJ.

J Hypertens. 2007 Oct;25(10):2008-10. No abstract available.

PMID:
17885541
33.

Urocortin 2 infusion in human heart failure.

Davis ME, Pemberton CJ, Yandle TG, Fisher SF, Lainchbury JG, Frampton CM, Rademaker MT, Richards M.

Eur Heart J. 2007 Nov;28(21):2589-97. Epub 2007 Aug 25.

PMID:
17720993
34.

Characterisation of proghrelin peptides in mammalian tissue and plasma.

Bang AS, Soule SG, Yandle TG, Richards AM, Pemberton CJ.

J Endocrinol. 2007 Feb;192(2):313-23.

PMID:
17283231
35.

Urocortin 2 infusion in healthy humans: hemodynamic, neurohormonal, and renal responses.

Davis ME, Pemberton CJ, Yandle TG, Fisher SF, Lainchbury JG, Frampton CM, Rademaker MT, Richards AM.

J Am Coll Cardiol. 2007 Jan 30;49(4):461-71. Epub 2007 Jan 12.

36.

Cardiovascular effects of native and non-native urotensin II and urotensin II-related peptide on rat and salmon hearts.

Prosser HC, Leprince J, Vaudry H, Richards AM, Forster ME, Pemberton CJ.

Peptides. 2006 Dec;27(12):3261-8. Epub 2006 Nov 9.

PMID:
17097764
37.

Resistin worsens cardiac ischaemia-reperfusion injury.

Rothwell SE, Richards AM, Pemberton CJ.

Biochem Biophys Res Commun. 2006 Oct 13;349(1):400-7. Epub 2006 Aug 18.

PMID:
16934751
38.

Plasma cardiotrophin-1 is elevated in human hypertension and stimulated by ventricular stretch.

Pemberton CJ, Raudsepp SD, Yandle TG, Cameron VA, Richards AM.

Cardiovasc Res. 2005 Oct 1;68(1):109-17.

PMID:
15978561
39.

Effect of urocortin 1 infusion in humans with stable congestive cardiac failure.

Davis ME, Pemberton CJ, Yandle TG, Lainchbury JG, Rademaker MT, Nicholls MG, Frampton CM, Richards AM.

Clin Sci (Lond). 2005 Oct;109(4):381-8.

PMID:
15882144
40.

Ghrelin induces vasoconstriction in the rat coronary vasculature without altering cardiac peptide secretion.

Pemberton CJ, Tokola H, Bagi Z, Koller A, Pöntinen J, Ola A, Vuolteenaho O, Szokodi I, Ruskoaho H.

Am J Physiol Heart Circ Physiol. 2004 Oct;287(4):H1522-9. Epub 2004 May 13.

41.

Urocortin-1 infusion in normal humans.

Davis ME, Pemberton CJ, Yandle TG, Lainchbury JG, Rademaker MT, Nicholls MG, Frampton CM, Richards AM.

J Clin Endocrinol Metab. 2004 Mar;89(3):1402-9.

PMID:
15001641
42.

Immunoreactive forms of natriuretic peptides in ovine brain: response to heart failure.

Pemberton CJ, Yandle TG, Espiner EA.

Peptides. 2002 Dec;23(12):2235-44.

PMID:
12535704
43.

Deconvolution analysis of cardiac natriuretic peptides during acute volume overload.

Pemberton CJ, Johnson ML, Yandle TG, Espiner EA.

Hypertension. 2000 Sep;36(3):355-9.

PMID:
10988264
44.

Neurohormones in an ovine model of compensated postinfarction left ventricular dysfunction.

Rademaker MT, Cameron VA, Charles CJ, Espiner EA, Nicholls MG, Pemberton CJ, Richards AM.

Am J Physiol Heart Circ Physiol. 2000 Mar;278(3):H731-40.

45.

Amino-terminal proBNP in ovine plasma: evidence for enhanced secretion in response to cardiac overload.

Pemberton CJ, Yandle TG, Rademaker MT, Charles CJ, Aitken GD, Espiner EA.

Am J Physiol. 1998 Oct;275(4):H1200-8. doi: 10.1152/ajpheart.1998.275.4.H1200.

PMID:
9746467
46.

Ovine brain natriuretic peptide in cardiac tissues and plasma: effects of cardiac hypertrophy and heart failure on tissue concentration and molecular forms.

Pemberton CJ, Yandle TG, Charles CJ, Rademaker MT, Aitken GD, Espiner EA.

J Endocrinol. 1997 Dec;155(3):541-50.

PMID:
9487999
47.

Natriuretic peptides in sheep with pressure overload left ventricular hypertrophy.

Charles CJ, Kaaja RJ, Espiner EA, Nicholls MG, Pemberton CJ, Richards AM, Yandle TG.

Clin Exp Hypertens. 1996 Nov;18(8):1051-71.

PMID:
8922345
48.

Single medial injection peribulbar anaesthesia using prilocaine.

Brahma AK, Pemberton CJ, Ayeko M, Morgan LH.

Anaesthesia. 1994 Nov;49(11):1003-5.

49.

Peribulbar and retrobulbar anesthesia with prilocaine: a comparison of two methods of local ocular anesthesia.

Saunders DC, Sturgess DA, Pemberton CJ, Morgan LH, Bourne A.

Ophthalmic Surg. 1993 Dec;24(12):842-5.

PMID:
8115101

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