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Items: 1 to 50 of 64

1.

A family of radical halogenases for the engineering of amino-acid-based products.

Neugebauer ME, Sumida KH, Pelton JG, McMurry JL, Marchand JA, Chang MCY.

Nat Chem Biol. 2019 Oct;15(10):1009-1016. doi: 10.1038/s41589-019-0355-x. Epub 2019 Sep 23.

PMID:
31548692
2.

Discovery of a pathway for terminal-alkyne amino acid biosynthesis.

Marchand JA, Neugebauer ME, Ing MC, Lin CI, Pelton JG, Chang MCY.

Nature. 2019 Mar;567(7748):420-424. doi: 10.1038/s41586-019-1020-y. Epub 2019 Mar 13.

PMID:
30867596
3.

Unconstrained peptoid tetramer exhibits a predominant conformation in aqueous solution.

Roe LT, Pelton JG, Edison JR, Butterfoss GL, Tresca BW, LaFaye BA, Whitelam S, Wemmer DE, Zuckermann RN.

Biopolymers. 2019 Jun;110(6):e23267. doi: 10.1002/bip.23267. Epub 2019 Mar 5.

PMID:
30835821
4.

Structure and Function of the Transmembrane Domain of NsaS, an Antibiotic Sensing Histidine Kinase in Staphylococcus aureus.

Bhate MP, Lemmin T, Kuenze G, Mensa B, Ganguly S, Peters JM, Schmidt N, Pelton JG, Gross CA, Meiler J, DeGrado WF.

J Am Chem Soc. 2018 Jun 20;140(24):7471-7485. doi: 10.1021/jacs.7b09670. Epub 2018 Jun 9.

5.

Entropy drives selective fluorine recognition in the fluoroacetyl-CoA thioesterase from Streptomyces cattleya.

Weeks AM, Wang N, Pelton JG, Chang MCY.

Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):E2193-E2201. doi: 10.1073/pnas.1717077115. Epub 2018 Feb 16.

6.

Survey of solution dynamics in Src kinase reveals allosteric cross talk between the ligand binding and regulatory sites.

Tong M, Pelton JG, Gill ML, Zhang W, Picart F, Seeliger MA.

Nat Commun. 2017 Dec 18;8(1):2160. doi: 10.1038/s41467-017-02240-6.

7.

A facile method for expression and purification of (15)N isotope-labeled human Alzheimer's β-amyloid peptides from E. coli for NMR-based structural analysis.

Sharma SC, Armand T, Ball KA, Chen A, Pelton JG, Wemmer DE, Head-Gordon T.

Protein Expr Purif. 2015 Dec;116:82-9. doi: 10.1016/j.pep.2015.07.012. Epub 2015 Jul 29.

8.

Solution structure of the porcine sapovirus VPg core reveals a stable three-helical bundle with a conserved surface patch.

Hwang HJ, Min HJ, Yun H, Pelton JG, Wemmer DE, Cho KO, Kim JS, Lee CW.

Biochem Biophys Res Commun. 2015 Apr 17;459(4):610-6. doi: 10.1016/j.bbrc.2015.02.156. Epub 2015 Mar 6.

PMID:
25753201
9.

DNA recognition by a σ(54) transcriptional activator from Aquifex aeolicus.

Vidangos NK, Heideker J, Lyubimov A, Lamers M, Huo Y, Pelton JG, Ton J, Gralla J, Berger J, Wemmer DE.

J Mol Biol. 2014 Oct 23;426(21):3553-68. doi: 10.1016/j.jmb.2014.08.009. Epub 2014 Aug 23.

10.

The novel catabolic pathway of 3,6-anhydro-L-galactose, the main component of red macroalgae, in a marine bacterium.

Yun EJ, Lee S, Kim HT, Pelton JG, Kim S, Ko HJ, Choi IG, Kim KH.

Environ Microbiol. 2015 May;17(5):1677-88. doi: 10.1111/1462-2920.12607. Epub 2014 Sep 29.

PMID:
25156229
11.

Selective chromium(VI) ligands identified using combinatorial peptoid libraries.

Knight AS, Zhou EY, Pelton JG, Francis MB.

J Am Chem Soc. 2013 Nov 20;135(46):17488-93. doi: 10.1021/ja408788t. Epub 2013 Nov 6.

12.

Structural analysis of autoinhibition in the Ras-specific exchange factor RasGRP1.

Iwig JS, Vercoulen Y, Das R, Barros T, Limnander A, Che Y, Pelton JG, Wemmer DE, Roose JP, Kuriyan J.

Elife. 2013 Jul 30;2:e00813. doi: 10.7554/eLife.00813.

13.

Structure, function, and tethering of DNA-binding domains in σ⁵⁴ transcriptional activators.

Vidangos N, Maris AE, Young A, Hong E, Pelton JG, Batchelor JD, Wemmer DE.

Biopolymers. 2013 Dec;99(12):1082-96. doi: 10.1002/bip.22333.

14.

13C NMR metabolomic evaluation of immediate and delayed mild hypothermia in cerebrocortical slices after oxygen-glucose deprivation.

Liu J, Segal MR, Kelly MJ, Pelton JG, Kim M, James TL, Litt L.

Anesthesiology. 2013 Nov;119(5):1120-36. doi: 10.1097/ALN.0b013e31829c2d90.

15.

1H nuclear magnetic resonance brain metabolomics in neonatal mice after hypoxia-ischemia distinguished normothermic recovery from mild hypothermia recoveries.

Liu J, Sheldon RA, Segal MR, Kelly MJ, Pelton JG, Ferriero DM, James TL, Litt L.

Pediatr Res. 2013 Aug;74(2):170-9. doi: 10.1038/pr.2013.88. Epub 2013 May 24.

16.

Conformational coupling across the plasma membrane in activation of the EGF receptor.

Endres NF, Das R, Smith AW, Arkhipov A, Kovacs E, Huang Y, Pelton JG, Shan Y, Shaw DE, Wemmer DE, Groves JT, Kuriyan J.

Cell. 2013 Jan 31;152(3):543-56. doi: 10.1016/j.cell.2012.12.032.

17.

Zinc drives a tertiary fold in the prion protein with familial disease mutation sites at the interface.

Spevacek AR, Evans EG, Miller JL, Meyer HC, Pelton JG, Millhauser GL.

Structure. 2013 Feb 5;21(2):236-46. doi: 10.1016/j.str.2012.12.002. Epub 2013 Jan 3.

18.

Enzymatic production of 3,6-anhydro-L-galactose from agarose and its purification and in vitro skin whitening and anti-inflammatory activities.

Yun EJ, Lee S, Kim JH, Kim BB, Kim HT, Lee SH, Pelton JG, Kang NJ, Choi IG, Kim KH.

Appl Microbiol Biotechnol. 2013 Apr;97(7):2961-70. doi: 10.1007/s00253-012-4184-z. Epub 2012 Jun 8.

PMID:
22678025
19.

Metabolomics of oxidative stress in recent studies of endogenous and exogenously administered intermediate metabolites.

Liu J, Litt L, Segal MR, Kelly MJ, Pelton JG, Kim M.

Int J Mol Sci. 2011;12(10):6469-501. doi: 10.3390/ijms12106469. Epub 2011 Sep 28. Review.

20.

A sterile alpha-motif domain in NafY targets apo-NifDK for iron-molybdenum cofactor delivery via a tethered domain.

Hernandez JA, Phillips AH, Erbil WK, Zhao D, Demuez M, Zeymer C, Pelton JG, Wemmer DE, Rubio LM.

J Biol Chem. 2011 Feb 25;286(8):6321-8. doi: 10.1074/jbc.M110.168732. Epub 2010 Dec 14.

21.

The Rut pathway for pyrimidine degradation: novel chemistry and toxicity problems.

Kim KS, Pelton JG, Inwood WB, Andersen U, Kustu S, Wemmer DE.

J Bacteriol. 2010 Aug;192(16):4089-102. doi: 10.1128/JB.00201-10. Epub 2010 Apr 16. Erratum in: J Bacteriol. 2011 Jan;193(1):326.

22.

Phosphorylation-induced conformational changes in the retinoblastoma protein inhibit E2F transactivation domain binding.

Burke JR, Deshong AJ, Pelton JG, Rubin SM.

J Biol Chem. 2010 May 21;285(21):16286-93. doi: 10.1074/jbc.M110.108167. Epub 2010 Mar 11.

23.

Structure and regulatory mechanism of Aquifex aeolicus NtrC4: variability and evolution in bacterial transcriptional regulation.

Batchelor JD, Doucleff M, Lee CJ, Matsubara K, De Carlo S, Heideker J, Lamers MH, Pelton JG, Wemmer DE.

J Mol Biol. 2008 Dec 31;384(5):1058-75. doi: 10.1016/j.jmb.2008.10.024. Epub 2008 Oct 17.

PMID:
18955063
24.

Identification of a DNA primase template tracking site redefines the geometry of primer synthesis.

Corn JE, Pelton JG, Berger JM.

Nat Struct Mol Biol. 2008 Feb;15(2):163-9. doi: 10.1038/nsmb.1373. Epub 2008 Jan 13.

PMID:
18193061
25.

NMR structure of the N-terminal domain of the replication initiator protein DnaA.

Lowery TJ, Pelton JG, Chandonia JM, Kim R, Yokota H, Wemmer DE.

J Struct Funct Genomics. 2007 Mar;8(1):11-7. Epub 2007 Aug 7.

PMID:
17680349
26.

Structural basis of DNA recognition by the alternative sigma-factor, sigma54.

Doucleff M, Pelton JG, Lee PS, Nixon BT, Wemmer DE.

J Mol Biol. 2007 Jun 15;369(4):1070-8. Epub 2007 Apr 12.

27.

A dimeric kinase assembly underlying autophosphorylation in the p21 activated kinases.

Pirruccello M, Sondermann H, Pelton JG, Pellicena P, Hoelz A, Chernoff J, Wemmer DE, Kuriyan J.

J Mol Biol. 2006 Aug 11;361(2):312-26. Epub 2006 Jun 27.

PMID:
16837009
28.

Structural studies of MJ1529, an O6-methylguanine-DNA methyltransferase.

Roberts A, Pelton JG, Wemmer DE.

Magn Reson Chem. 2006 Jul;44 Spec No:S71-82.

PMID:
16826543
29.

SAS solution structures of the apo and Mg2+/BeF3(-)-bound receiver domain of DctD from Sinorhizobium meliloti.

Nixon BT, Yennawar HP, Doucleff M, Pelton JG, Wemmer DE, Krueger S, Kondrashkina E.

Biochemistry. 2005 Oct 25;44(42):13962-9.

PMID:
16229485
30.

The C-terminal RpoN domain of sigma54 forms an unpredicted helix-turn-helix motif similar to domains of sigma70.

Doucleff M, Malak LT, Pelton JG, Wemmer DE.

J Biol Chem. 2005 Dec 16;280(50):41530-6. Epub 2005 Oct 6.

31.

NMR structure of hypothetical protein MG354 from Mycoplasma genitalium.

Pelton JG, Shi J, Yokota H, Kim R, Wemmer DE.

Proteins. 2005 Nov 15;61(3):666-8. No abstract available.

PMID:
16184596
32.

Biophysical characterization of the interaction domains and mapping of the contact residues in the XPF-ERCC1 complex.

Choi YJ, Ryu KS, Ko YM, Chae YK, Pelton JG, Wemmer DE, Choi BS.

J Biol Chem. 2005 Aug 5;280(31):28644-52. Epub 2005 Jun 1.

33.

Solution structure of a putative ribosome binding protein from Mycoplasma pneumoniae and comparison to a distant homolog.

Rubin SM, Pelton JG, Yokota H, Kim R, Wemmer DE.

J Struct Funct Genomics. 2003;4(4):235-43.

PMID:
15185964
34.

Protein signal assignments using specific labeling and cell-free synthesis.

Shi J, Pelton JG, Cho HS, Wemmer DE.

J Biomol NMR. 2004 Mar;28(3):235-47.

PMID:
14752257
35.

Phosphoaspartates in bacterial signal transduction.

Cho HS, Pelton JG, Yan D, Kustu S, Wemmer DE.

Curr Opin Struct Biol. 2001 Dec;11(6):679-84. Review.

PMID:
11751048
36.

A novel engineered subtilisin BPN' lacking a low-barrier hydrogen bond in the catalytic triad.

Stratton JR, Pelton JG, Kirsch JF.

Biochemistry. 2001 Sep 4;40(35):10411-6.

PMID:
11523982
37.

Crystal structure of activated CheY. Comparison with other activated receiver domains.

Lee SY, Cho HS, Pelton JG, Yan D, Berry EA, Wemmer DE.

J Biol Chem. 2001 May 11;276(19):16425-31. Epub 2001 Feb 13.

38.

Crystal structure of an activated response regulator bound to its target.

Lee SY, Cho HS, Pelton JG, Yan D, Henderson RK, King DS, Huang L, Kustu S, Berry EA, Wemmer DE.

Nat Struct Biol. 2001 Jan;8(1):52-6.

PMID:
11135671
39.

NMR structure of activated CheY.

Cho HS, Lee SY, Yan D, Pan X, Parkinson JS, Kustu S, Wemmer DE, Pelton JG.

J Mol Biol. 2000 Mar 31;297(3):543-51.

PMID:
10731410
40.

Development and use of a virtual NMR facility.

Keating KA, Myers JD, Pelton JG, Bair RA, Wemmer DE, Ellis PD.

J Magn Reson. 2000 Mar;143(1):172-83.

PMID:
10698658
41.

Beryllofluoride mimics phosphorylation of NtrC and other bacterial response regulators.

Yan D, Cho HS, Hastings CA, Igo MM, Lee SY, Pelton JG, Stewart V, Wemmer DE, Kustu S.

Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):14789-94.

42.

Assignment of cytosine N3 resonances in nucleic acids via intrabase three-bond coupling to amino protons.

Rüdisser S, Pelton JG, Tinoco I Jr.

J Biomol NMR. 1999 Oct;15(2):173-6.

PMID:
10605090
43.

Solution structure of the DNA-binding domain of NtrC with three alanine substitutions.

Pelton JG, Kustu S, Wemmer DE.

J Mol Biol. 1999 Oct 8;292(5):1095-110.

PMID:
10512705
44.

Mapping of a protein-RNA kissing hairpin interface: Rom and Tar-Tar*.

Comolli LR, Pelton JG, Tinoco I Jr.

Nucleic Acids Res. 1998 Oct 15;26(20):4688-95.

45.

Sequence specific 1HN, 15N, 1H alpha, 13C alpha, and 13C beta assignments for RNA-1 modulator protein ROM.

Pelton JG, Comolli LR.

J Biomol NMR. 1998 May;11(4):463-4. No abstract available.

PMID:
9691290
46.
47.

Structure of the acid state of Escherichia coli ribonuclease HI.

Dabora JM, Pelton JG, Marqusee S.

Biochemistry. 1996 Sep 17;35(37):11951-8.

PMID:
8810899
48.

Yeast heat shock transcription factor N-terminal activation domains are unstructured as probed by heteronuclear NMR spectroscopy.

Cho HS, Liu CW, Damberger FF, Pelton JG, Nelson HC, Wemmer DE.

Protein Sci. 1996 Feb;5(2):262-9.

49.

Refined solution structure and dynamics of the DNA-binding domain of the heat shock factor from Kluyveromyces lactis.

Damberger FF, Pelton JG, Liu C, Cho H, Harrison CJ, Nelson HC, Wemmer DE.

J Mol Biol. 1995 Dec 8;254(4):704-19.

PMID:
7500344
50.

Interaction of minor groove ligands to an AAATT/AATTT site: correlation of thermodynamic characterization and solution structure.

Rentzeperis D, Marky LA, Dwyer TJ, Geierstanger BH, Pelton JG, Wemmer DE.

Biochemistry. 1995 Mar 7;34(9):2937-45.

PMID:
7893707

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