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Extra corporeal membrane oxygenation in the critical trauma patient.

Della Torre V, Robba C, Pelosi P, Bilotta F.

Curr Opin Anaesthesiol. 2019 Jan 2. doi: 10.1097/ACO.0000000000000698. [Epub ahead of print]


High-flow nasal cannula oxygen therapy in patients undergoing thoracic surgery: current evidence and practice.

Wittenstein J, Ball L, Pelosi P, Gama de Abreu M.

Curr Opin Anaesthesiol. 2019 Feb;32(1):44-49. doi: 10.1097/ACO.0000000000000682.


Outcomes of Patients Presenting with Mild Acute Respiratory Distress Syndrome: Insights from the LUNG SAFE Study.

Pham T, Serpa Neto A, Pelosi P, Laffey JG, De Haro C, Lorente JA, Bellani G, Fan E, Brochard LJ, Pesenti A, Schultz MJ, Artigas A; LUNG SAFE Investigators and the European Society of Intensive Care Medicine Trials Group.

Anesthesiology. 2018 Nov 27. doi: 10.1097/ALN.0000000000002508. [Epub ahead of print]


Should we titrate ventilation based on driving pressure? Maybe not in the way we would expect.

Pelosi P, Ball L.

Ann Transl Med. 2018 Oct;6(19):389. doi: 10.21037/atm.2018.09.48. Review.


Respiratory mechanics during general anaesthesia.

Ball L, Costantino F, Fiorito M, Amodio S, Pelosi P.

Ann Transl Med. 2018 Oct;6(19):379. doi: 10.21037/atm.2018.09.50. Review.


Respiratory mechanics in mechanically ventilated patients: from physiology to clinical practice at the bedside.

Pelosi P, Ball L.

Ann Transl Med. 2018 Oct;6(19):375. doi: 10.21037/atm.2018.09.61. No abstract available.


Supplemental oxygen or something else?

Silva PL, Pelosi P, Rocco PRM.

J Thorac Dis. 2018 Sep;10(Suppl 26):S3211-S3214. doi: 10.21037/jtd.2018.08.06. No abstract available.


Effect of a Low vs Intermediate Tidal Volume Strategy on Ventilator-Free Days in Intensive Care Unit Patients Without ARDS: A Randomized Clinical Trial.

Writing Group for the PReVENT Investigators, Simonis FD, Serpa Neto A, Binnekade JM, Braber A, Bruin KCM, Determann RM, Goekoop GJ, Heidt J, Horn J, Innemee G, de Jonge E, Juffermans NP, Spronk PE, Steuten LM, Tuinman PR, de Wilde RBP, Vriends M, Gama de Abreu M, Pelosi P, Schultz MJ.

JAMA. 2018 Nov 13;320(18):1872-1880. doi: 10.1001/jama.2018.14280.


Appraisal of systemic inflammation and diagnostic markers in a porcine model of VAP: secondary analysis from a study on novel preventive strategies.

Li Bassi G, Prats RG, Artigas A, Xiol EA, Marti JD, Ranzani OT, Rigol M, Fernandez L, Meli A, Battaglini D, Luque N, Ferrer M, Martin-Loeches I, Póvoa P, Chiumello D, Pelosi P, Torres A.

Intensive Care Med Exp. 2018 Oct 20;6(1):42. doi: 10.1186/s40635-018-0206-1.


Transcranial color-coded duplex sonography for bedside monitoring of central nervous system infection as a consequence of decompressive craniectomy after traumatic brain injury.

Robba C, Simonassi F, Ball L, Pelosi P.

Intensive Care Med. 2018 Oct 9. doi: 10.1007/s00134-018-5405-4. [Epub ahead of print] No abstract available.


How to optimize critical care resources in surgical patients: intensive care without physical borders.

Pelosi P, Ball L, Schultz MJ.

Curr Opin Crit Care. 2018 Dec;24(6):581-587. doi: 10.1097/MCC.0000000000000557.


Perioperative management of obese patient.

Bazurro S, Ball L, Pelosi P.

Curr Opin Crit Care. 2018 Dec;24(6):560-567. doi: 10.1097/MCC.0000000000000555.


In-vitro analysis of a novel 'add-on' silicone cuff to improve sealing properties of tracheal tubes.

Li Bassi G, Chiurazzi C, Aguilera E, Travierso C, Battaglini D, Yang M, Motos A, Yang H, Meli A, Marti D, Ranzani OT, Blasi F, Pelosi P, Chiumello D, Torres A.

Anaesthesia. 2018 Nov;73(11):1372-1381. doi: 10.1111/anae.14413.


Mechanical power of ventilation is associated with mortality in critically ill patients: an analysis of patients in two observational cohorts.

Serpa Neto A, Deliberato RO, Johnson AEW, Bos LD, Amorim P, Pereira SM, Cazati DC, Cordioli RL, Correa TD, Pollard TJ, Schettino GPP, Timenetsky KT, Celi LA, Pelosi P, Gama de Abreu M, Schultz MJ; PROVE Network Investigators.

Intensive Care Med. 2018 Nov;44(11):1914-1922. doi: 10.1007/s00134-018-5375-6. Epub 2018 Oct 5.


Focal ischemic stroke leads to lung injury and reduces alveolar macrophage phagocytic capability in rats.

Samary CS, Ramos AB, Maia LA, Rocha NN, Santos CL, Magalhães RF, Clevelario AL, Pimentel-Coelho PM, Mendez-Otero R, Cruz FF, Capelozzi VL, Ferreira TPT, Koch T, de Abreu MG, Dos Santos CC, Pelosi P, Silva PL, Rocco PRM.

Crit Care. 2018 Oct 5;22(1):249. doi: 10.1186/s13054-018-2164-0.


Odorant-Binding Proteins as Sensing Elements for Odour Monitoring.

Pelosi P, Zhu J, Knoll W.

Sensors (Basel). 2018 Sep 27;18(10). pii: E3248. doi: 10.3390/s18103248. Review.


Individual Positive End-expiratory Pressure Settings Optimize Intraoperative Mechanical Ventilation and Reduce Postoperative Atelectasis.

Pereira SM, Tucci MR, Morais CCA, Simões CM, Tonelotto BFF, Pompeo MS, Kay FU, Pelosi P, Vieira JE, Amato MBP.

Anesthesiology. 2018 Dec;129(6):1070-1081. doi: 10.1097/ALN.0000000000002435.


Intraoperative ventilation settings and their associations with postoperative pulmonary complications in obese patients.

Ball L, Hemmes SNT, Serpa Neto A, Bluth T, Canet J, Hiesmayr M, Hollmann MW, Mills GH, Vidal Melo MF, Putensen C, Schmid W, Severgnini P, Wrigge H, Gama de Abreu M, Schultz MJ, Pelosi P; LAS VEGAS investigators; PROVE Network; Clinical Trial Network of the European Society of Anaesthesiology.

Br J Anaesth. 2018 Oct;121(4):899-908. doi: 10.1016/j.bja.2018.04.021. Epub 2018 Jun 2.


Neuromuscular blocking agents and postoperative pulmonary complications.

Ball L, de Abreu MG, Schultz MJ, Pelosi P.

Lancet Respir Med. 2018 Sep 14. pii: S2213-2600(18)30363-1. doi: 10.1016/S2213-2600(18)30363-1. [Epub ahead of print] No abstract available.


Temporal Changes in Ventilator Settings in Patients With Uninjured Lungs: A Systematic Review.

Schaefer MS, Serpa Neto A, Pelosi P, Gama de Abreu M, Kienbaum P, Schultz MJ, Meyer-Treschan TA.

Anesth Analg. 2018 Sep 12. doi: 10.1213/ANE.0000000000003758. [Epub ahead of print]


Lung protection during one-lung ventilation: Another piece in the puzzle.

Ball L, Robba C, Gama de Abreu M, Pelosi P.

Eur J Anaesthesiol. 2018 Oct;35(10):724-726. doi: 10.1097/EJA.0000000000000879. No abstract available.


Pressure support ventilation + sigh in acute hypoxemic respiratory failure patients: study protocol for a pilot randomized controlled trial, the PROTECTION trial.

Mauri T, Foti G, Fornari C, Constantin JM, Guerin C, Pelosi P, Ranieri M, Conti S, Tubiolo D, Rondelli E, Lovisari F, Fossali T, Spadaro S, Grieco DL, Navalesi P, Calamai I, Becher T, Roca O, Wang YM, Knafelj R, Cortegiani A, Mancebo J, Brochard L, Pesenti A; Protection Study Group.

Trials. 2018 Aug 29;19(1):460. doi: 10.1186/s13063-018-2828-8.


Magnetic Resonance Imaging for Quantitative Assessment of Lung Aeration: A Pilot Translational Study.

Ball L, Braune A, Spieth P, Herzog M, Chandrapatham K, Hietschold V, Schultz MJ, Patroniti N, Pelosi P, Gama de Abreu M.

Front Physiol. 2018 Aug 13;9:1120. doi: 10.3389/fphys.2018.01120. eCollection 2018.


The European Medicines Agency and the Authorization for Hydroxyethyl starch Containing Solutions-Killing the Cow to Get Rid of Ticks?

Wittenstein J, Pelosi P, de Abreu MG.

Turk J Anaesthesiol Reanim. 2018 Jun;46(3):168-169. doi: 10.5152/TJAR.2018.120618. Epub 2017 Jun 1. No abstract available.


International multicenter observational study on assessment of ventilatory management during general anaesthesia for robotic surgery and its effects on postoperative pulmonary complication (AVATaR): study protocol and statistical analysis plan.

Queiroz VNF, da Costa LGV, Barbosa RP, Takaoka F, De Baerdemaeker L, Cesar DS, D'Orto UC, Galdi JR, Gottumukkala V, Cata JP, Hemmes SNT, Hollman MW, Kalmar A, Moura LAB, Mariano RM, Matot I, Mazzinari G, Mills GH, Posso IP, Teruya A, Vidal Melo MF, Sprung J, Weingarten TN, Treschan TA, Koopman S, Eidelman L, Chen LL, Lee JW, Ariño Irujo JJ, Tena B, Groeben H, Pelosi P, de Abreu MG, Schultz MJ, Serpa Neto A; AVATaR and PROVE Network investigators.

BMJ Open. 2018 Aug 23;8(8):e021643. doi: 10.1136/bmjopen-2018-021643.


Carbon dioxide dynamics in relation to neurological outcome in resuscitated out-of-hospital cardiac arrest patients: an exploratory Target Temperature Management Trial substudy.

Ebner F, Harmon MBA, Aneman A, Cronberg T, Friberg H, Hassager C, Juffermans N, Kjærgaard J, Kuiper M, Mattsson N, Pelosi P, Ullén S, Undén J, Wise MP, Nielsen N.

Crit Care. 2018 Aug 18;22(1):196. doi: 10.1186/s13054-018-2119-5.


Hemodynamic management of critically ill burn patients: an international survey.

Soussi S, Berger MM, Colpaert K, Dünser MW, Guttormsen AB, Juffermans NP, Knape P, Koksal G, Lavrentieva A, Leclerc T, Lorente JA, Martin-Loeches I, Metnitz P, Pantet O, Pelosi P, Rousseau AF, Sjöberg F, Legrand M; ESICM Burn ICU working group.

Crit Care. 2018 Aug 17;22(1):194. doi: 10.1186/s13054-018-2129-3. No abstract available.


From radioactive ligands to biosensors: binding methods with olfactory proteins.

Pelosi P, Zhu J, Knoll W.

Appl Microbiol Biotechnol. 2018 Oct;102(19):8213-8227. doi: 10.1007/s00253-018-9253-5. Epub 2018 Jul 27. Review.


Periodic Fluctuation of Tidal Volumes Further Improves Variable Ventilation in Experimental Acute Respiratory Distress Syndrome.

Güldner A, Huhle R, Beda A, Kiss T, Bluth T, Rentzsch I, Kerber S, Carvalho NC, Kasper M, Pelosi P, de Abreu MG.

Front Physiol. 2018 Jul 12;9:905. doi: 10.3389/fphys.2018.00905. eCollection 2018.


Between hypoxia or hyperoxia: not perfect but more physiologic.

Robba C, Ball L, Pelosi P.

J Thorac Dis. 2018 Jun;10(Suppl 17):S2052-S2054. doi: 10.21037/jtd.2018.05.129. No abstract available.


Association between pre-operative biological phenotypes and postoperative pulmonary complications: An unbiased cluster analysis.

Serpa Neto A, Bos LD, Campos PPZA, Hemmes SNT, Bluth T, Calfee CS, Ferner M, Güldner A, Hollmann MW, India I, Kiss T, Laufenberg-Feldmann R, Sprung J, Sulemanji D, Unzueta C, Vidal Melo MF, Weingarten TN, Tuip-de Boer AM, Pelosi P, Gama de Abreu M, Schultz MJ; PROVHILO* and the PROVE** investigators.

Eur J Anaesthesiol. 2018 Sep;35(9):702-709. doi: 10.1097/EJA.0000000000000846.


The LAS VEGAS risk score for prediction of postoperative pulmonary complications: An observational study.

Neto AS, da Costa LGV, Hemmes SNT, Canet J, Hedenstierna G, Jaber S, Hiesmayr M, Hollmann MW, Mills GH, Vidal Melo MF, Pearse R, Putensen C, Schmid W, Severgnini P, Wrigge H, Gama de Abreu M, Pelosi P, Schultz MJ; LAS VEGAS.

Eur J Anaesthesiol. 2018 Sep;35(9):691-701. doi: 10.1097/EJA.0000000000000845.


Balanced Crystalloids Versus Saline for Perioperative Intravenous Fluid Administration in Children Undergoing Neurosurgery: A Randomized Clinical Trial.

Lima MF, Neville IS, Cavalheiro S, Bourguignon DC, Pelosi P, Malbouisson LMS.

J Neurosurg Anesthesiol. 2019 Jan;31(1):30-35. doi: 10.1097/ANA.0000000000000515.


Performances of CPAP Devices With an Oronasal Mask.

Vargas M, Marra A, Vivona L, Ball L, Marinò V, Pelosi P, Servillo G.

Respir Care. 2018 Aug;63(8):1033-1039. doi: 10.4187/respcare.05930. Epub 2018 May 29.


Practice of mechanical ventilation in cardiac arrest patients and effects of targeted temperature management: A substudy of the targeted temperature management trial.

Harmon MBA, van Meenen DMP, van der Veen ALIP, Binnekade JM, Dankiewicz J, Ebner F, Nielsen N, Pelosi P, Schultz MJ, Horn J, Friberg H, Juffermans NP; TTM trial investigators.

Resuscitation. 2018 Aug;129:29-36. doi: 10.1016/j.resuscitation.2018.04.040. Epub 2018 May 12.


Individualized, perioperative, hemodynamic goal-directed therapy in major abdominal surgery (iPEGASUS trial): study protocol for a randomized controlled trial.

Funcke S, Saugel B, Koch C, Schulte D, Zajonz T, Sander M, Gratarola A, Ball L, Pelosi P, Spadaro S, Ragazzi R, Volta CA, Mencke T, Zitzmann A, Neukirch B, Azparren G, Giné M, Moral V, Pinnschmidt HO, Díaz-Cambronero O, Estelles MJA, Velez ME, Montañes MV, Belda J, Soro M, Puig J, Reuter DA, Haas SA.

Trials. 2018 May 9;19(1):273. doi: 10.1186/s13063-018-2620-9.


RELAx - REstricted versus Liberal positive end-expiratory pressure in patients without ARDS: protocol for a randomized controlled trial.

Algera AG, Pisani L, Bergmans DCJ, den Boer S, de Borgie CAJ, Bosch FH, Bruin K, Cherpanath TG, Determann RM, Dondorp AM, Dongelmans DA, Endeman H, Haringman JJ, Horn J, Juffermans NP, van Meenen DM, van der Meer NJ, Merkus MP, Moeniralam HS, Purmer I, Tuinman PR, Slabbekoorn M, Spronk PE, Vlaar APJ, Gama de Abreu M, Pelosi P, Serpa Neto A, Schultz MJ, Paulus F; RELAx Investigators and the PROVE Network Investigators.

Trials. 2018 May 9;19(1):272. doi: 10.1186/s13063-018-2640-5.


Tracheostomy in intensive care: Patients and families will never walk alone!

Pelosi P, Ball L, Brunetti I, Vargas M, Patroniti N.

Anaesth Crit Care Pain Med. 2018 Jun;37(3):197-199. doi: 10.1016/j.accpm.2018.04.001. No abstract available.


PRactice of VENTilation in Middle-Income Countries (PRoVENT-iMIC): rationale and protocol for a prospective international multicentre observational study in intensive care units in Asia.

Pisani L, Algera AG, Serpa Neto A, Ahsan A, Beane A, Chittawatanarat K, Faiz A, Haniffa R, Hashemian R, Hashmi M, Imad HA, Indraratna K, Iyer S, Kayastha G, Krishna B, Moosa H, Nadjm B, Pattnaik R, Sampath S, Thwaites L, Tun NN, Yunos NM, Grasso S, Paulus F, de Abreu MG, Pelosi P, Dondorp AM, Schultz MJ; PRoVENT–iMIC investigators, MORU and the PROVE network.

BMJ Open. 2018 Apr 28;8(4):e020841. doi: 10.1136/bmjopen-2017-020841.


Impact of Different Tidal Volume Levels at Low Mechanical Power on Ventilator-Induced Lung Injury in Rats.

Moraes L, Silva PL, Thompson A, Santos CL, Santos RS, Fernandes MVS, Morales MM, Martins V, Capelozzi VL, de Abreu MG, Pelosi P, Rocco PRM.

Front Physiol. 2018 Apr 4;9:318. doi: 10.3389/fphys.2018.00318. eCollection 2018.


The fragility of statistically significant findings in randomised controlled anaesthesiology trials: systematic review of the medical literature.

Mazzinari G, Ball L, Serpa Neto A, Errando CL, Dondorp AM, Bos LD, Gama de Abreu M, Pelosi P, Schultz MJ.

Br J Anaesth. 2018 May;120(5):935-941. doi: 10.1016/j.bja.2018.01.012. Epub 2018 Feb 13. Review.


A systematic review and consensus definitions for standardised end-points in perioperative medicine: pulmonary complications.

Abbott TEF, Fowler AJ, Pelosi P, Gama de Abreu M, Møller AM, Canet J, Creagh-Brown B, Mythen M, Gin T, Lalu MM, Futier E, Grocott MP, Schultz MJ, Pearse RM; StEP-COMPAC Group.

Br J Anaesth. 2018 May;120(5):1066-1079. doi: 10.1016/j.bja.2018.02.007. Epub 2018 Mar 27. Review.


Reply to: high versus low positive end-expiratory pressure for abdominal surgery.

Treschan TA, Gama de Abreu M, Pelosi P, Schultz MJ; PROVE Network Investigators.

Eur J Anaesthesiol. 2018 Jan;35(1):67-68. doi: 10.1097/EJA.0000000000000719. No abstract available.


Odorant-binding protein-based identification of natural spatial repellents for the African malaria mosquito Anopheles gambiae.

Kröber T, Koussis K, Bourquin M, Tsitoura P, Konstantopoulou M, Awolola TS, Dani FR, Qiao H, Pelosi P, Iatrou K, Guerin PM.

Insect Biochem Mol Biol. 2018 May;96:36-50. doi: 10.1016/j.ibmb.2018.03.008. Epub 2018 Apr 12.


Proteomic analysis of chemosensory organs in the honey bee parasite Varroa destructor: A comprehensive examination of the potential carriers for semiochemicals.

Iovinella I, McAfee A, Mastrobuoni G, Kempa S, Foster LJ, Pelosi P, Dani FR.

J Proteomics. 2018 Jun 15;181:131-141. doi: 10.1016/j.jprot.2018.04.009. Epub 2018 Apr 10.


A death pheromone, oleic acid, triggers hygienic behavior in honey bees (Apis mellifera L.).

McAfee A, Chapman A, Iovinella I, Gallagher-Kurtzke Y, Collins TF, Higo H, Madilao LL, Pelosi P, Foster LJ.

Sci Rep. 2018 Apr 9;8(1):5719. doi: 10.1038/s41598-018-24054-2.


Ventilator-induced lung injury during controlled ventilation in patients with acute respiratory distress syndrome: less is probably better.

Cruz FF, Ball L, Rocco PRM, Pelosi P.

Expert Rev Respir Med. 2018 May;12(5):403-414. doi: 10.1080/17476348.2018.1457954. Epub 2018 Mar 29.


Acute exacerbation of idiopathic pulmonary fibrosis: lessons learned from acute respiratory distress syndrome?

Marchioni A, Tonelli R, Ball L, Fantini R, Castaniere I, Cerri S, Luppi F, Malerba M, Pelosi P, Clini E.

Crit Care. 2018 Mar 23;22(1):80. doi: 10.1186/s13054-018-2002-4. Review.


Potentially modifiable respiratory variables contributing to outcome in ICU patients without ARDS: a secondary analysis of PRoVENT.

Simonis FD, Barbas CSV, Artigas-Raventós A, Canet J, Determann RM, Anstey J, Hedenstierna G, Hemmes SNT, Hermans G, Hiesmayr M, Hollmann MW, Jaber S, Martin-Loeches I, Mills GH, Pearse RM, Putensen C, Schmid W, Severgnini P, Smith R, Treschan TA, Tschernko EM, Vidal Melo MF, Wrigge H, de Abreu MG, Pelosi P, Schultz MJ, Neto AS; PRoVENT investigators; PROVE Network investigators.

Ann Intensive Care. 2018 Mar 21;8(1):39. doi: 10.1186/s13613-018-0385-7.

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