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Transcription factors implicated in late megakaryopoiesis as markers of outcome after azacitidine and allogeneic stem cell transplantation in myelodysplastic syndrome.

Falconi G, Fabiani E, Criscuolo M, Fianchi L, Finelli C, Cerqui E, Pelosi E, Screnci M, Gurnari C, Zangrilli I, Postorino M, Laurenti L, Piciocchi A, Testa U, Lo-Coco F, Voso MT.

Leuk Res. 2019 Sep;84:106191. doi: 10.1016/j.leukres.2019.106191. Epub 2019 Jul 19.


Cellular and Molecular Mechanisms Underlying Prostate Cancer Development: Therapeutic Implications.

Testa U, Castelli G, Pelosi E.

Medicines (Basel). 2019 Jul 30;6(3). pii: E82. doi: 10.3390/medicines6030082. Review.


Author Correction: Human sex reversal is caused by duplication or deletion of core enhancers upstream of SOX9.

Croft B, Ohnesorg T, Hewitt J, Bowles J, Quinn A, Tan J, Corbin V, Pelosi E, van den Bergen J, Sreenivasan R, Knarston I, Robevska G, Vu DC, Hutson J, Harley V, Ayers K, Koopman P, Sinclair A.

Nat Commun. 2019 Jul 23;10(1):3351. doi: 10.1038/s41467-019-11310-w.


Emerging Therapies for Acute Myelogenus Leukemia Patients Targeting Apoptosis and Mitochondrial Metabolism.

Castelli G, Pelosi E, Testa U.

Cancers (Basel). 2019 Feb 22;11(2). pii: E260. doi: 10.3390/cancers11020260. Review.


Human sex reversal is caused by duplication or deletion of core enhancers upstream of SOX9.

Croft B, Ohnesorg T, Hewitt J, Bowles J, Quinn A, Tan J, Corbin V, Pelosi E, van den Bergen J, Sreenivasan R, Knarston I, Robevska G, Vu DC, Hutson J, Harley V, Ayers K, Koopman P, Sinclair A.

Nat Commun. 2018 Dec 14;9(1):5319. doi: 10.1038/s41467-018-07784-9. Erratum in: Nat Commun. 2019 Jul 23;10(1):3351.


Identification of Candidate Genes for Mayer-Rokitansky-Küster-Hauser Syndrome Using Genomic Approaches.

Backhouse B, Hanna C, Robevska G, van den Bergen J, Pelosi E, Simons C, Koopman P, Juniarto AZ, Grover S, Faradz S, Sinclair A, Ayers K, Tan TY.

Sex Dev. 2019;13(1):26-34. doi: 10.1159/000494896. Epub 2018 Dec 1.


The small-molecule compound AC-73 targeting CD147 inhibits leukemic cell proliferation, induces autophagy and increases the chemotherapeutic sensitivity of acute myeloid leukemia cells.

Spinello I, Saulle E, Quaranta MT, Pasquini L, Pelosi E, Castelli G, Ottone T, Voso MT, Testa U, Labbaye C.

Haematologica. 2019 May;104(5):973-985. doi: 10.3324/haematol.2018.199661. Epub 2018 Nov 22.


Genetic Abnormalities, Clonal Evolution, and Cancer Stem Cells of Brain Tumors.

Testa U, Castelli G, Pelosi E.

Med Sci (Basel). 2018 Oct 2;6(4). pii: E85. doi: 10.3390/medsci6040085. Review.


Congenital syphilis presenting with liver lesions.

Deall H, Faust SN, Pelosi E, Fairhurst J, Elliott K, Patel S.

Int J STD AIDS. 2019 Jan;30(1):82-85. doi: 10.1177/0956462418779311. Epub 2018 Aug 16.


Lung Cancers: Molecular Characterization, Clonal Heterogeneity and Evolution, and Cancer Stem Cells.

Testa U, Castelli G, Pelosi E.

Cancers (Basel). 2018 Jul 27;10(8). pii: E248. doi: 10.3390/cancers10080248. Review.


miR-146 and miR-155: Two Key Modulators of Immune Response and Tumor Development.

Testa U, Pelosi E, Castelli G, Labbaye C.

Noncoding RNA. 2017 Jun 26;3(3). pii: E22. doi: 10.3390/ncrna3030022. Review.


Colorectal cancer: genetic abnormalities, tumor progression, tumor heterogeneity, clonal evolution and tumor-initiating cells.

Testa U, Pelosi E, Castelli G.

Med Sci (Basel). 2018 Apr 13;6(2). pii: E31. doi: 10.3390/medsci6020031. Review.


Ovarian Cancers: Genetic Abnormalities, Tumor Heterogeneity and Progression, Clonal Evolution and Cancer Stem Cells.

Testa U, Petrucci E, Pasquini L, Castelli G, Pelosi E.

Medicines (Basel). 2018 Feb 1;5(1). pii: E16. doi: 10.3390/medicines5010016. Review.


Targeting histone methyltransferase and demethylase in acute myeloid leukemia therapy.

Castelli G, Pelosi E, Testa U.

Onco Targets Ther. 2017 Dec 28;11:131-155. doi: 10.2147/OTT.S145971. eCollection 2018. Review.


Lhx8 ablation leads to massive autophagy of mouse oocytes associated with DNA damage.

D'Ignazio L, Michel M, Beyer M, Thompson K, Forabosco A, Schlessinger D, Pelosi E.

Biol Reprod. 2018 Apr 1;98(4):532-542. doi: 10.1093/biolre/iox184.


Effect of miR-204&211 and RUNX2 control on the fate of human mesenchymal stromal cells.

Sacchetti B, Fatica A, Sorci M, Sorrentino A, Signore M, Cerio A, Felicetti F, Feo A, Pelosi E, Caré A, Pescarmona E, Gordeladze JO, Valtieri M.

Regen Med Res. 2017;5:2. doi: 10.1051/rmr/170004. Epub 2017 Dec 5.


Melanoma: Genetic Abnormalities, Tumor Progression, Clonal Evolution and Tumor Initiating Cells.

Testa U, Castelli G, Pelosi E.

Med Sci (Basel). 2017 Nov 20;5(4). pii: E28. doi: 10.3390/medsci5040028. Review.


Pancreatic Cancer: Molecular Characterization, Clonal Evolution and Cancer Stem Cells.

Pelosi E, Castelli G, Testa U.

Biomedicines. 2017 Nov 18;5(4). pii: E65. doi: 10.3390/biomedicines5040065. Review.


The forkhead box C1 (FOXC1) transcription factor is downregulated in acute promyelocytic leukemia.

Fabiani E, Falconi G, Noguera NI, Saulle E, Cicconi L, Divona M, Banella C, Picardi A, Cerio AM, Boe L, Sanchez M, Pelosi E, Testa U, Lo-Coco F, Voso MT.

Oncotarget. 2017 Sep 20;8(48):84074-84085. doi: 10.18632/oncotarget.21101. eCollection 2017 Oct 13.


Mechanisms of anti-cancer effects of ascorbate: Cytotoxic activity and epigenetic modulation.

Mastrangelo D, Pelosi E, Castelli G, Lo-Coco F, Testa U.

Blood Cells Mol Dis. 2018 Mar;69:57-64. doi: 10.1016/j.bcmd.2017.09.005. Epub 2017 Sep 21. Review.


Esophageal Cancer: Genomic and Molecular Characterization, Stem Cell Compartment and Clonal Evolution.

Testa U, Castelli G, Pelosi E.

Medicines (Basel). 2017 Sep 14;4(3). pii: E67. doi: 10.3390/medicines4030067. Review.


Liver Cancer: Molecular Characterization, Clonal Evolution and Cancer Stem Cells.

Castelli G, Pelosi E, Testa U.

Cancers (Basel). 2017 Sep 20;9(9). pii: E127. doi: 10.3390/cancers9090127. Review.


A Rare Case of Hibernoma Occasionally Identified by 18F-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in a Patient with Lung Cancer.

Penna D, Quartuccio N, Testa C, Arena V, Cistaro A, Pelosi E.

Cureus. 2017 Mar 29;9(3):e1124. doi: 10.7759/cureus.1124.


High-dose ascorbate and arsenic trioxide selectively kill acute myeloid leukemia and acute promyelocytic leukemia blasts in vitro.

Noguera NI, Pelosi E, Angelini DF, Piredda ML, Guerrera G, Piras E, Battistini L, Massai L, Berardi A, Catalano G, Cicconi L, Castelli G, D'Angiò A, Pasquini L, Graziani G, Fioritoni G, Voso MT, Mastrangelo D, Testa U, Lo-Coco F.

Oncotarget. 2017 May 16;8(20):32550-32565. doi: 10.18632/oncotarget.15925.


Corticosteroid-responsive focal granulomatous herpes simplex type-1 encephalitis in adults.

Varatharaj A, Nicoll JA, Pelosi E, Pinto AA.

Pract Neurol. 2017 Apr;17(2):140-144. doi: 10.1136/practneurol-2016-001474. Epub 2017 Feb 2.


Targeted therapies in the treatment of adult acute myeloid leukemias: current status and future perspectives.

Castelli G, Pelosi E, Testa U.

Int J Hematol Oncol. 2016 Dec;5(4):143-164. doi: 10.2217/ijh-2016-0011. Epub 2017 Feb 7. Review.


Conditioned medium from human umbilical vein endothelial cells markedly improves the proliferation and differentiation of circulating endothelial progenitors.

Castelli G, Parolini I, Cerio AM, D'Angiò A, Pasquini L, Carollo M, Sargiacomo M, Testa U, Pelosi E.

Blood Cells Mol Dis. 2016 Oct;61:58-65. doi: 10.1016/j.bcmd.2016.07.007. Epub 2016 Aug 18.


Endothelial progenitor cells in hematologic malignancies.

Testa U, Saulle E, Castelli G, Pelosi E.

Stem Cell Investig. 2016 Jul 1;3:26. doi: 10.21037/sci.2016.06.07. eCollection 2016. Review.


Incidental irradiation of internal mammary lymph nodes in breast cancer: conventional two-dimensional radiotherapy versus conformal three-dimensional radiotherapy.

Leite ET, Ugino RT, Santana MA, Ferreira DV, Lopes MR, Pelosi EL, da Silva JL, Carvalho Hde A.

Radiol Bras. 2016 May-Jun;49(3):170-5. doi: 10.1590/0100-3984.2015.0003.


Oxidative stress and hypoxia in normal and leukemic stem cells.

Testa U, Labbaye C, Castelli G, Pelosi E.

Exp Hematol. 2016 Jul;44(7):540-60. doi: 10.1016/j.exphem.2016.04.012. Epub 2016 May 12. Review.


PML-RAR alpha induces the downmodulation of HHEX: a key event responsible for the induction of an angiogenetic response.

Saulle E, Petronelli A, Pelosi E, Coppotelli E, Pasquini L, Ilari R, Lo-Coco F, Testa U.

J Hematol Oncol. 2016 Apr 7;9:33. doi: 10.1186/s13045-016-0262-5.


WNT/β-catenin and p27/FOXL2 differentially regulate supporting cell proliferation in the developing ovary.

Gustin SE, Hogg K, Stringer JM, Rastetter RH, Pelosi E, Miles DC, Sinclair AH, Wilhelm D, Western PS.

Dev Biol. 2016 Apr 15;412(2):250-60. doi: 10.1016/j.ydbio.2016.02.024. Epub 2016 Mar 3.


Severe Enterovirus Infections in Hospitalized Children in the South of England: Clinical Phenotypes and Causative Genotypes.

de Graaf H, Pelosi E, Cooper A, Pappachan J, Sykes K, MacIntosh I, Gbesemete D, Clark TW, Patel SV, Faust SN, Tebruegge M.

Pediatr Infect Dis J. 2016 Jul;35(7):723-7. doi: 10.1097/INF.0000000000001093.


Genetics of the ovarian reserve.

Pelosi E, Forabosco A, Schlessinger D.

Front Genet. 2015 Oct 15;6:308. doi: 10.3389/fgene.2015.00308. eCollection 2015. Review.


Targeting LSCs through membrane antigens selectively or preferentially expressed on these cells.

Pelosi E, Castelli G, Testa U.

Blood Cells Mol Dis. 2015 Dec;55(4):336-46. doi: 10.1016/j.bcmd.2015.07.015. Epub 2015 Jul 26. Review.


18F-FDG PET/CT in the post-operative monitoring of patients with adrenocortical carcinoma.

Ardito A, Massaglia C, Pelosi E, Zaggia B, Basile V, Brambilla R, Vigna-Taglianti F, Duregon E, Arena V, Perotti P, Penna D, Terzolo M.

Eur J Endocrinol. 2015 Dec;173(6):749-56. doi: 10.1530/EJE-15-0707. Epub 2015 Sep 7.


Cytotoxic effects of high concentrations of sodium ascorbate on human myeloid cell lines.

Mastrangelo D, Massai L, Lo Coco F, Noguera NI, Borgia L, Fioritoni G, Berardi A, Iacone A, Muscettola M, Pelosi E, Castelli G, Testa U, Di Pisa F, Grasso G.

Ann Hematol. 2015 Nov;94(11):1807-16. doi: 10.1007/s00277-015-2464-2. Epub 2015 Aug 12.


FOXL2 modulates cartilage, skeletal development and IGF1-dependent growth in mice.

Marongiu M, Marcia L, Pelosi E, Lovicu M, Deiana M, Zhang Y, Puddu A, Loi A, Uda M, Forabosco A, Schlessinger D, Crisponi L.

BMC Dev Biol. 2015 Jul 2;15:27. doi: 10.1186/s12861-015-0072-y.


Differential hypoxic regulation of the microRNA-146a/CXCR4 pathway in normal and leukemic monocytic cells: impact on response to chemotherapy.

Spinello I, Quaranta MT, Paolillo R, Pelosi E, Cerio AM, Saulle E, Lo Coco F, Testa U, Labbaye C.

Haematologica. 2015 Sep;100(9):1160-71. doi: 10.3324/haematol.2014.120295. Epub 2015 Jun 4.


Human TM9SF4 Is a New Gene Down-Regulated by Hypoxia and Involved in Cell Adhesion of Leukemic Cells.

Paolillo R, Spinello I, Quaranta MT, Pasquini L, Pelosi E, Lo Coco F, Testa U, Labbaye C.

PLoS One. 2015 May 11;10(5):e0126968. doi: 10.1371/journal.pone.0126968. eCollection 2015.


Dynamics of the ovarian reserve and impact of genetic and epidemiological factors on age of menopause.

Pelosi E, Simonsick E, Forabosco A, Garcia-Ortiz JE, Schlessinger D.

Biol Reprod. 2015 May;92(5):130. doi: 10.1095/biolreprod.114.127381. Epub 2015 Apr 22. Review.


miR-21 is overexpressed in NPM1-mutant acute myeloid leukemias.

Riccioni R, Lulli V, Castelli G, Biffoni M, Tiberio R, Pelosi E, Lo-Coco F, Testa U.

Leuk Res. 2015 Feb;39(2):221-8. doi: 10.1016/j.leukres.2014.11.001. Epub 2014 Nov 18.


A miRNA Signature in Human Cord Blood Stem and Progenitor Cells as Potential Biomarker of Specific Acute Myeloid Leukemia Subtypes.

Cattaneo M, Pelosi E, Castelli G, Cerio AM, D'Angiò A, Porretti L, Rebulla P, Pavesi L, Russo G, Giordano A, Turri J, Cicconi L, Lo-Coco F, Testa U, Biunno I.

J Cell Physiol. 2015 Aug;230(8):1770-80. doi: 10.1002/jcp.24876.


18F-FDG-PET/CT in a Patient with Suspected Large Vessel Vasculitis.

Penna D, Testa C, Arena V, Pelosi E.

J Clin Diagn Res. 2014 Oct;8(10):RJ02-3. doi: 10.7860/JCDR/2014/8283.5035. Epub 2014 Oct 20. No abstract available.


Human cord blood-derived hemogenic endothelium generates mast cells.

Castelli G, D'Angiò A, Grassi G, Costa V, Pasquini L, Tiberio R, Cerio AM, Testa U, Tripodi M, Pelosi E.

Blood Cells Mol Dis. 2015 Feb;54(2):195-7. doi: 10.1016/j.bcmd.2014.11.002. Epub 2014 Nov 15. No abstract available.


MicroRNAs expressed in hematopoietic stem/progenitor cells are deregulated in acute myeloid leukemias.

Testa U, Pelosi E.

Leuk Lymphoma. 2015 May;56(5):1466-74. doi: 10.3109/10428194.2014.955019. Epub 2015 Jan 21. Review.


Intraoperative radiation therapy in early breast cancer using a linear accelerator outside of the operative suite: an "image-guided" approach.

Hanna SA, de Barros ACSD, de Andrade FEM, Bevilacqua JLB, Piato JRM, Pelosi EL, Martella E, da Silva JLF, Carvalho HA.

Int J Radiat Oncol Biol Phys. 2014 Aug 1;89(5):1015-1023. doi: 10.1016/j.ijrobp.2014.04.038. Epub 2014 Jul 8.


β-Blockers promote angiogenesis in the mouse aortic ring assay.

Stati T, Musumeci M, Maccari S, Massimi A, Corritore E, Strimpakos G, Pelosi E, Catalano L, Marano G.

J Cardiovasc Pharmacol. 2014 Jul;64(1):21-7. doi: 10.1097/FJC.0000000000000085.


CD 123 is a membrane biomarker and a therapeutic target in hematologic malignancies.

Testa U, Pelosi E, Frankel A.

Biomark Res. 2014 Feb 10;2(1):4. doi: 10.1186/2050-7771-2-4.


FOXL2 transcriptionally represses Sf1 expression by antagonizing WT1 during ovarian development in mice.

Takasawa K, Kashimada K, Pelosi E, Takagi M, Morio T, Asahara H, Schlessinger D, Mizutani S, Koopman P.

FASEB J. 2014 May;28(5):2020-8. doi: 10.1096/fj.13-246108. Epub 2014 Jan 22.

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