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Items: 29


Resolution of Cellular Heterogeneity in Human Prostate Cancers: Implications for Diagnosis and Treatment.

Maitland NJ, Frame FM, Rane JK, Erb HH, Packer JR, Archer LK, Pellacani D.

Adv Exp Med Biol. 2019;1164:207-224. doi: 10.1007/978-3-030-22254-3_16. Review.


Transcriptional regulation of normal human mammary cell heterogeneity and its perturbation in breast cancer.

Pellacani D, Tan S, Lefort S, Eaves CJ.

EMBO J. 2019 Jul 15;38(14):e100330. doi: 10.15252/embj.2018100330. Epub 2019 Jan 11. Review.


A topological view of human CD34+ cell state trajectories from integrated single-cell output and proteomic data.

Knapp DJHF, Hammond CA, Wang F, Aghaeepour N, Miller PH, Beer PA, Pellacani D, VanInsberghe M, Hansen C, Bendall SC, Nolan GP, Eaves CJ.

Blood. 2019 Feb 28;133(9):927-939. doi: 10.1182/blood-2018-10-878025. Epub 2019 Jan 8.


Phenotype-independent DNA methylation changes in prostate cancer.

Pellacani D, Droop AP, Frame FM, Simms MS, Mann VM, Collins AT, Eaves CJ, Maitland NJ.

Br J Cancer. 2018 Oct;119(9):1133-1143. doi: 10.1038/s41416-018-0236-1. Epub 2018 Oct 15.


Single-cell analysis identifies a CD33+ subset of human cord blood cells with high regenerative potential.

Knapp DJHF, Hammond CA, Hui T, van Loenhout MTJ, Wang F, Aghaeepour N, Miller PH, Moksa M, Rabu GM, Beer PA, Pellacani D, Humphries RK, Hansen C, Hirst M, Eaves CJ.

Nat Cell Biol. 2018 Jun;20(6):710-720. doi: 10.1038/s41556-018-0104-5. Epub 2018 May 25.


Mass Cytometric Analysis Reveals Viable Activated Caspase-3+ Luminal Progenitors in the Normal Adult Human Mammary Gland.

Knapp DJHF, Kannan N, Pellacani D, Eaves CJ.

Cell Rep. 2017 Oct 24;21(4):1116-1126. doi: 10.1016/j.celrep.2017.09.096.


Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy.

Lan X, Jörg DJ, Cavalli FMG, Richards LM, Nguyen LV, Vanner RJ, Guilhamon P, Lee L, Kushida MM, Pellacani D, Park NI, Coutinho FJ, Whetstone H, Selvadurai HJ, Che C, Luu B, Carles A, Moksa M, Rastegar N, Head R, Dolma S, Prinos P, Cusimano MD, Das S, Bernstein M, Arrowsmith CH, Mungall AJ, Moore RA, Ma Y, Gallo M, Lupien M, Pugh TJ, Taylor MD, Hirst M, Eaves CJ, Simons BD, Dirks PB.

Nature. 2017 Sep 14;549(7671):227-232. doi: 10.1038/nature23666. Epub 2017 Aug 30.


Dissociation of Survival, Proliferation, and State Control in Human Hematopoietic Stem Cells.

Knapp DJ, Hammond CA, Miller PH, Rabu GM, Beer PA, Ricicova M, Lecault V, Da Costa D, VanInsberghe M, Cheung AM, Pellacani D, Piret J, Hansen C, Eaves CJ.

Stem Cell Reports. 2017 Jan 10;8(1):152-162. doi: 10.1016/j.stemcr.2016.12.003.


Analysis of Normal Human Mammary Epigenomes Reveals Cell-Specific Active Enhancer States and Associated Transcription Factor Networks.

Pellacani D, Bilenky M, Kannan N, Heravi-Moussavi A, Knapp DJHF, Gakkhar S, Moksa M, Carles A, Moore R, Mungall AJ, Marra MA, Jones SJM, Aparicio S, Hirst M, Eaves CJ.

Cell Rep. 2016 Nov 15;17(8):2060-2074. doi: 10.1016/j.celrep.2016.10.058.


Distinct signaling programs control human hematopoietic stem cell survival and proliferation.

Knapp DJ, Hammond CA, Aghaeepour N, Miller PH, Pellacani D, Beer PA, Sachs K, Qiao W, Wang W, Humphries RK, Sauvageau G, Zandstra PW, Bendall SC, Nolan GP, Hansen C, Eaves CJ.

Blood. 2017 Jan 19;129(3):307-318. doi: 10.1182/blood-2016-09-740654. Epub 2016 Nov 8.


Harvesting Human Prostate Tissue Material and Culturing Primary Prostate Epithelial Cells.

Frame FM, Pellacani D, Collins AT, Maitland NJ.

Methods Mol Biol. 2016;1443:181-201. doi: 10.1007/978-1-4939-3724-0_12.


Barcoding reveals complex clonal dynamics of de novo transformed human mammary cells.

Nguyen LV, Pellacani D, Lefort S, Kannan N, Osako T, Makarem M, Cox CL, Kennedy W, Beer P, Carles A, Moksa M, Bilenky M, Balani S, Babovic S, Sun I, Rosin M, Aparicio S, Hirst M, Eaves CJ.

Nature. 2015 Dec 10;528(7581):267-71. doi: 10.1038/nature15742. Epub 2015 Dec 2.


DNA barcoding reveals diverse growth kinetics of human breast tumour subclones in serially passaged xenografts.

Nguyen LV, Cox CL, Eirew P, Knapp DJ, Pellacani D, Kannan N, Carles A, Moksa M, Balani S, Shah S, Hirst M, Aparicio S, Eaves CJ.

Nat Commun. 2014 Dec 23;5:5871. doi: 10.1038/ncomms6871.


MicroRNA expression profile of primary prostate cancer stem cells as a source of biomarkers and therapeutic targets.

Rane JK, Scaravilli M, Ylipää A, Pellacani D, Mann VM, Simms MS, Nykter M, Collins AT, Visakorpi T, Maitland NJ.

Eur Urol. 2015 Jan;67(1):7-10. doi: 10.1016/j.eururo.2014.09.005. Epub 2014 Sep 16.


Conserved two-step regulatory mechanism of human epithelial differentiation.

Rane JK, Droop AP, Pellacani D, Polson ES, Simms MS, Collins AT, Caves LS, Maitland NJ.

Stem Cell Reports. 2014 Feb 6;2(2):180-8. doi: 10.1016/j.stemcr.2014.01.001. eCollection 2014 Feb 11.


DNA hypermethylation in prostate cancer is a consequence of aberrant epithelial differentiation and hyperproliferation.

Pellacani D, Kestoras D, Droop AP, Frame FM, Berry PA, Lawrence MG, Stower MJ, Simms MS, Mann VM, Collins AT, Risbridger GP, Maitland NJ.

Cell Death Differ. 2014 May;21(5):761-73. doi: 10.1038/cdd.2013.202. Epub 2014 Jan 24.


HDAC inhibitor confers radiosensitivity to prostate stem-like cells.

Frame FM, Pellacani D, Collins AT, Simms MS, Mann VM, Jones GD, Meuth M, Bristow RG, Maitland NJ.

Br J Cancer. 2013 Dec 10;109(12):3023-33. doi: 10.1038/bjc.2013.691. Epub 2013 Nov 12.


Differential cytotoxic activity of a novel palladium-based compound on prostate cell lines, primary prostate epithelial cells and prostate stem cells.

Ulukaya E, Frame FM, Cevatemre B, Pellacani D, Walker H, Mann VM, Simms MS, Stower MJ, Yilmaz VT, Maitland NJ.

PLoS One. 2013 May 10;8(5):e64278. doi: 10.1371/journal.pone.0064278. Print 2013.


Retinoic acid represses invasion and stem cell phenotype by induction of the metastasis suppressors RARRES1 and LXN.

Oldridge EE, Walker HF, Stower MJ, Simms MS, Mann VM, Collins AT, Pellacani D, Maitland NJ.

Oncogenesis. 2013 Apr 15;2:e45. doi: 10.1038/oncsis.2013.6.


Prominin-1 (CD133) Expression in the Prostate and Prostate Cancer: A Marker for Quiescent Stem Cells.

Pellacani D, Oldridge EE, Collins AT, Maitland NJ.

Adv Exp Med Biol. 2013;777:167-84. doi: 10.1007/978-1-4614-5894-4_11. Review.


Advanced prostate cancer--a case for adjuvant differentiation therapy.

Rane JK, Pellacani D, Maitland NJ.

Nat Rev Urol. 2012 Oct;9(10):595-602. doi: 10.1038/nrurol.2012.157. Epub 2012 Aug 14. Review.


Anticancer activity of green tea polyphenols in prostate gland.

Davalli P, Rizzi F, Caporali A, Pellacani D, Davoli S, Bettuzzi S, Brausi M, D'Arca D.

Oxid Med Cell Longev. 2012;2012:984219. doi: 10.1155/2012/984219. Epub 2012 May 15. Review.


Retinoic acid and androgen receptors combine to achieve tissue specific control of human prostatic transglutaminase expression: a novel regulatory network with broader significance.

Rivera-Gonzalez GC, Droop AP, Rippon HJ, Tiemann K, Pellacani D, Georgopoulos LJ, Maitland NJ.

Nucleic Acids Res. 2012 Jun;40(11):4825-40. doi: 10.1093/nar/gks143. Epub 2012 Feb 22.


Prostate cancer stem cells: are they androgen-responsive?

Oldridge EE, Pellacani D, Collins AT, Maitland NJ.

Mol Cell Endocrinol. 2012 Sep 5;360(1-2):14-24. doi: 10.1016/j.mce.2011.07.008. Epub 2011 Jul 23. Review.


Regulation of the stem cell marker CD133 is independent of promoter hypermethylation in human epithelial differentiation and cancer.

Pellacani D, Packer RJ, Frame FM, Oldridge EE, Berry PA, Labarthe MC, Stower MJ, Simms MS, Collins AT, Maitland NJ.

Mol Cancer. 2011 Jul 29;10:94. doi: 10.1186/1476-4598-10-94.


Stromal upregulation of lateral epithelial adhesions: gene expression analysis of signalling pathways in prostate epithelium.

Chambers KF, Pearson JF, Pellacani D, Aziz N, Gužvić M, Klein CA, Lang SH.

J Biomed Sci. 2011 Jun 22;18:45. doi: 10.1186/1423-0127-18-45.


Development and limitations of lentivirus vectors as tools for tracking differentiation in prostate epithelial cells.

Frame FM, Hager S, Pellacani D, Stower MJ, Walker HF, Burns JE, Collins AT, Maitland NJ.

Exp Cell Res. 2010 Nov 15;316(19):3161-71. doi: 10.1016/j.yexcr.2010.08.004. Epub 2010 Aug 19.


Genetic inactivation of ApoJ/clusterin: effects on prostate tumourigenesis and metastatic spread.

Bettuzzi S, Davalli P, Davoli S, Chayka O, Rizzi F, Belloni L, Pellacani D, Fregni G, Astancolle S, Fassan M, Corti A, Baffa R, Sala A.

Oncogene. 2009 Dec 10;28(49):4344-52. doi: 10.1038/onc.2009.286.


Micro neuraminidase-inhibition assay for classification of influenza A virus neuraminidases.

Van Deusen RA, Hinshaw VS, Senne DA, Pellacani D.

Avian Dis. 1983 Jul-Sep;27(3):745-50.


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