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The relationship between antihypertensive medications and mood disorders: analysis of linked healthcare data for 1.8 million patients.

Shaw RJ, Mackay D, Pell JP, Padmanabhan S, Bailey DS, Smith DJ.

Psychol Med. 2020 Jan 24:1-9. doi: 10.1017/S0033291719004094. [Epub ahead of print]


Contribution of type 2 diabetes to all-cause mortality, cardiovascular disease incidence and cancer incidence in white Europeans and South Asians: findings from the UK Biobank population-based cohort study.

Muilwijk M, Ho F, Waddell H, Sillars A, Welsh P, Iliodromiti S, Brown R, Ferguson L, Stronks K, van Valkengoed I, Pell JP, Gray SR, Gill JMR, Sattar N, Celis-Morales C.

BMJ Open Diabetes Res Care. 2019 Dec 17;7(1):e000765. doi: 10.1136/bmjdrc-2019-000765. eCollection 2019.


In Utero Antihypertensive Medication Exposure and Neonatal Outcomes: A Data Linkage Cohort Study.

Fitton CA, Fleming M, Steiner MFC, Aucott L, Pell JP, Mackay DF, Mclay JS.

Hypertension. 2019 Dec 30:HYPERTENSIONAHA11913802. doi: 10.1161/HYPERTENSIONAHA.119.13802. [Epub ahead of print]


Glycated Hemoglobin, Prediabetes, and the Links to Cardiovascular Disease: Data From UK Biobank.

Welsh C, Welsh P, Celis-Morales CA, Mark PB, Mackay D, Ghouri N, Ho FK, Ferguson LD, Brown R, Lewsey J, Cleland JG, Gray SR, Lyall DM, Anderson JJ, Jhund PS, Pell JP, McGuire DK, Gill JMR, Sattar N.

Diabetes Care. 2020 Feb;43(2):440-445. doi: 10.2337/dc19-1683. Epub 2019 Dec 18.


Response by Welsh et al to Letter Regarding Article, "Comparison of Conventional Lipoprotein Tests and Apolipoproteins in the Prediction of Cardiovascular Disease".

Welsh P, Welsh C, Pell J, Sattar N.

Circulation. 2019 Dec 10;140(24):e824-e825. doi: 10.1161/CIRCULATIONAHA.119.044325. Epub 2019 Dec 9. No abstract available.


Carotid Intima-Media Thickness: Novel Loci, Sex-Specific Effects, and Genetic Correlations With Obesity and Glucometabolic Traits in UK Biobank.

Strawbridge RJ, Ward J, Bailey MES, Cullen B, Ferguson A, Graham N, Johnston KJA, Lyall LM, Pearsall R, Pell J, Shaw RJ, Tank R, Lyall DM, Smith DJ.

Arterioscler Thromb Vasc Biol. 2020 Feb;40(2):446-461. doi: 10.1161/ATVBAHA.119.313226. Epub 2019 Dec 5.


UVA and Seasonal Patterning of 56 370 Myocardial Infarctions Across Scotland, 2000-2011.

Mackay DF, Clemens TL, Hastie CE, Cherrie MPC, Dibben C, Pell JP.

J Am Heart Assoc. 2019 Dec 3;8(23):e012551. doi: 10.1161/JAHA.119.012551. Epub 2019 Nov 21.


New versus old guidelines for sarcopenia classification: What is the impact on prevalence and health outcomes?

Petermann-Rocha F, Chen M, Gray SR, Ho FK, Pell JP, Celis-Morales C.

Age Ageing. 2019 Nov 15. pii: afz126. doi: 10.1093/ageing/afz126. [Epub ahead of print]


Glomerular filtration rate by differing measures, albuminuria and prediction of cardiovascular disease, mortality and end-stage kidney disease.

Lees JS, Welsh CE, Celis-Morales CA, Mackay D, Lewsey J, Gray SR, Lyall DM, Cleland JG, Gill JMR, Jhund PS, Pell J, Sattar N, Welsh P, Mark PB.

Nat Med. 2019 Nov;25(11):1753-1760. doi: 10.1038/s41591-019-0627-8. Epub 2019 Nov 7.


Association of Fitness and Grip Strength With Heart Failure: Findings From the UK Biobank Population-Based Study.

Sillars A, Celis-Morales CA, Ho FK, Petermann F, Welsh P, Iliodromiti S, Ferguson LD, Lyall DM, Anderson J, Mackay DF, Pellicori P, Cleland J, Pell JP, Gill JMR, Gray SR, Sattar N.

Mayo Clin Proc. 2019 Nov;94(11):2230-2240. doi: 10.1016/j.mayocp.2019.04.041.


Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9.

Schmidt AF, Holmes MV, Preiss D, Swerdlow DI, Denaxas S, Fatemifar G, Faraway R, Finan C, Valentine D, Fairhurst-Hunter Z, Hartwig FP, Horta BL, Hypponen E, Power C, Moldovan M, van Iperen E, Hovingh K, Demuth I, Norman K, Steinhagen-Thiessen E, Demuth J, Bertram L, Lill CM, Coassin S, Willeit J, Kiechl S, Willeit K, Mason D, Wright J, Morris R, Wanamethee G, Whincup P, Ben-Shlomo Y, McLachlan S, Price JF, Kivimaki M, Welch C, Sanchez-Galvez A, Marques-Vidal P, Nicolaides A, Panayiotou AG, Onland-Moret NC, van der Schouw YT, Matullo G, Fiorito G, Guarrera S, Sacerdote C, Wareham NJ, Langenberg C, Scott RA, Luan J, Bobak M, Malyutina S, Pająk A, Kubinova R, Tamosiunas A, Pikhart H, Grarup N, Pedersen O, Hansen T, Linneberg A, Jess T, Cooper J, Humphries SE, Brilliant M, Kitchner T, Hakonarson H, Carrell DS, McCarty CA, Lester KH, Larson EB, Crosslin DR, de Andrade M, Roden DM, Denny JC, Carty C, Hancock S, Attia J, Holliday E, Scott R, Schofield P, O'Donnell M, Yusuf S, Chong M, Pare G, van der Harst P, Said MA, Eppinga RN, Verweij N, Snieder H; Lifelines Cohort authors, Christen T, Mook-Kanamori DO; ICBP Consortium, Gustafsson S, Lind L, Ingelsson E, Pazoki R, Franco O, Hofman A, Uitterlinden A, Dehghan A, Teumer A, Baumeister S, Dörr M, Lerch MM, Völker U, Völzke H, Ward J, Pell JP, Meade T, Christophersen IE, Maitland-van der Zee AH, Baranova EV, Young R, Ford I, Campbell A, Padmanabhan S, Bots ML, Grobbee DE, Froguel P, Thuillier D, Roussel R, Bonnefond A, Cariou B, Smart M, Bao Y, Kumari M, Mahajan A, Hopewell JC, Seshadri S; METASTROKE Consortium of the ISGC, Dale C, Costa RPE, Ridker PM, Chasman DI, Reiner AP, Ritchie MD, Lange LA, Cornish AJ, Dobbins SE, Hemminki K, Kinnersley B, Sanson M, Labreche K, Simon M, Bondy M, Law P, Speedy H, Allan J, Li N, Went M, Weinhold N, Morgan G, Sonneveld P, Nilsson B, Goldschmidt H, Sud A, Engert A, Hansson M, Hemingway H, Asselbergs FW, Patel RS, Keating BJ, Sattar N, Houlston R, Casas JP, Hingorani AD.

BMC Cardiovasc Disord. 2019 Oct 29;19(1):240. doi: 10.1186/s12872-019-1187-z.


Depressive symptoms, neuroticism, and participation in breast and cervical cancer screening: Cross-sectional and prospective evidence from UK Biobank.

Niedzwiedz CL, Robb KA, Katikireddi SV, Pell JP, Smith DJ.

Psychooncology. 2019 Oct 30. doi: 10.1002/pon.5272. [Epub ahead of print]


In utero exposure to antidepressant medication and neonatal and child outcomes: a systematic review.

Fitton CA, Steiner MFC, Aucott L, Pell JP, Mackay DF, Fleming M, McLay JS.

Acta Psychiatr Scand. 2020 Jan;141(1):21-33. doi: 10.1111/acps.13120. Epub 2019 Nov 15. Review.


Neurodegenerative Disease Mortality among Former Professional Soccer Players.

Mackay DF, Russell ER, Stewart K, MacLean JA, Pell JP, Stewart W.

N Engl J Med. 2019 Nov 7;381(19):1801-1808. doi: 10.1056/NEJMoa1908483. Epub 2019 Oct 21.


Indicators of chronic noncommunicable diseases in women of reproductive age that are beneficiaries and non-beneficiaries of Bolsa Família.

Bernal RTI, Felisbino-Mendes MS, Carvalho QH, Pell J, Dundas R, Leyland A, Barreto ML, Malta DC.

Rev Bras Epidemiol. 2019 Oct 7;22Suppl 02(Suppl 02):E190012.SUPL.2. doi: 10.1590/1980-549720190012.supl.2. eCollection 2019. Portuguese, English.


Impact of major depression on cardiovascular outcomes for individuals with hypertension: prospective survival analysis in UK Biobank.

Graham N, Ward J, Mackay D, Pell JP, Cavanagh J, Padmanabhan S, Smith DJ.

BMJ Open. 2019 Sep 30;9(9):e024433. doi: 10.1136/bmjopen-2018-024433.


Effectiveness of Cardiac Rehabilitation on Health-related Quality of Life in Patients with Myocardial Infarction in Pakistan.

Ul-Haq Z, Khan D, Hisam A, Yousafzai YM, Hafeez S, Zulfiqar F, Gul AM, Hafizullah M, Pell J.

J Coll Physicians Surg Pak. 2019 Sep;29(9):803-809. doi: 10.29271/jcpsp.2019.09.803.


Gestational age at delivery of twins and perinatal outcomes: a cohort study in Aberdeen, Scotland.

Murray SR, Bhattacharya S, Stock SJ, Pell JP, Norman JE.

Version 2. Wellcome Open Res. 2019 Jul 22 [revised 2019 Jan 1];4:65. doi: 10.12688/wellcomeopenres.15211.2. eCollection 2019.


Understanding cognitive impairment in mood disorders: mediation analyses in the UK Biobank cohort.

Cullen B, Smith DJ, Deary IJ, Pell JP, Keyes KM, Evans JJ.

Br J Psychiatry. 2019 Aug 15:1-8. doi: 10.1192/bjp.2019.188. [Epub ahead of print]


Correction: The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with gene expression and function.

Ward J, Tunbridge EM, Sandor C, Lyall LM, Ferguson A, Strawbridge RJ, Lyall DM, Cullen B, Graham N, Johnston KJA, Webber C, Escott-Price V, O'Donovan M, Pell JP, Bailey MES, Harrison PJ, Smith DJ.

Mol Psychiatry. 2019 Jul 30. doi: 10.1038/s41380-019-0466-5. [Epub ahead of print]


Educational and Health Outcomes of Children Treated for Type 1 Diabetes: Scotland-Wide Record Linkage Study of 766,047 Children.

Fleming M, Fitton CA, Steiner MFC, McLay JS, Clark D, King A, Lindsay RS, Mackay DF, Pell JP.

Diabetes Care. 2019 Sep;42(9):1700-1707. doi: 10.2337/dc18-2423. Epub 2019 Jul 15.


Ten-Year Follow-Up of the Impact of Scottish Smoke-Free Legislation on Acute Myocardial Infarction.

Mackay DF, Pell JP.

Circ Cardiovasc Qual Outcomes. 2019 Jul;12(7):e005392. doi: 10.1161/CIRCOUTCOMES.118.005392. Epub 2019 Jul 9. No abstract available.


Antenatal exposure to solar radiation and learning disabilities: Population cohort study of 422,512 children.

Hastie CE, Mackay DF, Clemens TL, Cherrie MPC, King A, Dibben C, Pell JP.

Sci Rep. 2019 Jun 27;9(1):9356. doi: 10.1038/s41598-019-45562-9.


Impact of legislation to reduce the drink-drive limit on road traffic accidents and alcohol consumption in Scotland: a natural experiment study.

Lewsey J, Haghpanahan H, Mackay D, McIntosh E, Pell J, Jones A.

Southampton (UK): NIHR Journals Library; 2019 Jun.


Comparison of Conventional Lipoprotein Tests and Apolipoproteins in the Prediction of Cardiovascular Disease.

Welsh C, Celis-Morales CA, Brown R, Mackay DF, Lewsey J, Mark PB, Gray SR, Ferguson LD, Anderson JJ, Lyall DM, Cleland JG, Jhund PS, Gill JMR, Pell JP, Sattar N, Welsh P.

Circulation. 2019 Aug 13;140(7):542-552. doi: 10.1161/CIRCULATIONAHA.119.041149. Epub 2019 Jun 20.


The association of grip strength with health outcomes does not differ if grip strength is used in absolute or relative terms: a prospective cohort study.

Ho FKW, Celis-Morales CA, Petermann-Rocha F, Sillars A, Welsh P, Welsh C, Anderson J, Lyall DM, Mackay DF, Sattar N, Gill JMR, Pell JP, Gray SR.

Age Ageing. 2019 Sep 1;48(5):684-691. doi: 10.1093/ageing/afz068.


Educational and health outcomes of children treated for asthma: Scotland-wide record linkage study of 683 716 children.

Fleming M, Fitton CA, Steiner MFC, McLay JS, Clark D, King A, Mackay DF, Pell JP.

Eur Respir J. 2019 Sep 5;54(3). pii: 1802309. doi: 10.1183/13993003.02309-2018. Print 2019 Sep.


The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with gene expression and function.

Ward J, Tunbridge EM, Sandor C, Lyall LM, Ferguson A, Strawbridge RJ, Lyall DM, Cullen B, Graham N, Johnston KJA, Webber C, Escott-Price V, O'Donovan M, Pell JP, Bailey MES, Harrison PJ, Smith DJ.

Mol Psychiatry. 2019 Jun 5. doi: 10.1038/s41380-019-0439-8. [Epub ahead of print] Erratum in: Mol Psychiatry. 2019 Jul 30;:.


Do physical activity, commuting mode, cardiorespiratory fitness and sedentary behaviours modify the genetic predisposition to higher BMI? Findings from a UK Biobank study.

Celis-Morales CA, Lyall DM, Petermann F, Anderson J, Ward J, Iliodromiti S, Mackay DF, Welsh P, Bailey MES, Pell J, Sattar N, Gill JMR, Gray SR.

Int J Obes (Lond). 2019 Aug;43(8):1526-1538. doi: 10.1038/s41366-019-0381-5. Epub 2019 Jun 5.


Sex differences in the association between salivary telomere length and multimorbidity within the US Health & Retirement Study.

Niedzwiedz CL, Katikireddi SV, Pell JP, Smith DJ.

Age Ageing. 2019 Sep 1;48(5):703-710. doi: 10.1093/ageing/afz071.


Association of central adiposity with psoriasis, psoriatic arthritis and rheumatoid arthritis: a cross-sectional study of the UK Biobank.

Ferguson LD, Brown R, Celis-Morales C, Welsh P, Lyall DM, Pell JP, McInnes IB, Siebert S, Sattar N.

Rheumatology (Oxford). 2019 Dec 1;58(12):2137-2142. doi: 10.1093/rheumatology/kez192.


Football's InfluencE on Lifelong health and Dementia risk (FIELD): protocol for a retrospective cohort study of former professional footballers.

Russell ER, Stewart K, Mackay DF, MacLean J, Pell JP, Stewart W.

BMJ Open. 2019 May 22;9(5):e028654. doi: 10.1136/bmjopen-2018-028654.


Educational and health outcomes of children and adolescents receiving antiepileptic medication: Scotland-wide record linkage study of 766 244 schoolchildren.

Fleming M, Fitton CA, Steiner MFC, McLay JS, Clark D, King A, Mackay DF, Pell JP.

BMC Public Health. 2019 May 17;19(1):595. doi: 10.1186/s12889-019-6888-9.


Assessing for interaction between APOE ε4, sex, and lifestyle on cognitive abilities.

Lyall DM, Celis-Morales C, Lyall LM, Graham C, Graham N, Mackay DF, Strawbridge RJ, Ward J, Gill JMR, Sattar N, Cavanagh J, Smith DJ, Pell JP.

Neurology. 2019 Jun 4;92(23):e2691-e2698. doi: 10.1212/WNL.0000000000007551. Epub 2019 Apr 26.


Association between APOE e4 and white matter hyperintensity volume, but not total brain volume or white matter integrity.

Lyall DM, Cox SR, Lyall LM, Celis-Morales C, Cullen B, Mackay DF, Ward J, Strawbridge RJ, McIntosh AM, Sattar N, Smith DJ, Cavanagh J, Deary IJ, Pell JP.

Brain Imaging Behav. 2019 Mar 22. doi: 10.1007/s11682-019-00069-9. [Epub ahead of print]


The Combination of Physical Activity and Sedentary Behaviors Modifies the Genetic Predisposition to Obesity.

Celis-Morales CA, Lyall DM, Bailey MES, Petermann-Rocha F, Anderson J, Ward J, Mackay DF, Welsh P, Pell JP, Sattar N, Gill JMR, Gray SR.

Obesity (Silver Spring). 2019 Apr;27(4):653-661. doi: 10.1002/oby.22417.


Prostaglandin F2-Alpha Eye Drops (Bimatoprost) in Graves' Orbitopathy: A Randomized Controlled Double-Masked Crossover Trial (BIMA Trial).

Draman MS, Morris DS, Evans S, Haridas A, Pell J, Greenwood R, Foy C, Taylor P, Pooprasert P, Muller I, Zhang L, Lane C, Okosieme O, Ludgate M, Dayan C.

Thyroid. 2019 Apr;29(4):563-572. doi: 10.1089/thy.2018.0506. Epub 2019 Apr 1.


Healthy workers or less healthy leavers? Mortality in military veterans.

Bergman BP, Macdonald EB, Mackay DF, Pell JP.

Occup Med (Lond). 2019 Mar 7. pii: kqz023. doi: 10.1093/occmed/kqz023. [Epub ahead of print]


Associations between vascular risk factors and brain MRI indices in UK Biobank.

Cox SR, Lyall DM, Ritchie SJ, Bastin ME, Harris MA, Buchanan CR, Fawns-Ritchie C, Barbu MC, de Nooij L, Reus LM, Alloza C, Shen X, Neilson E, Alderson HL, Hunter S, Liewald DC, Whalley HC, McIntosh AM, Lawrie SM, Pell JP, Tucker-Drob EM, Wardlaw JM, Gale CR, Deary IJ.

Eur Heart J. 2019 Jul 21;40(28):2290-2300. doi: 10.1093/eurheartj/ehz100.


Optimization Sprints: Improving Clinician Satisfaction and Teamwork by Rapidly Reducing Electronic Health Record Burden.

Sieja A, Markley K, Pell J, Gonzalez C, Redig B, Kneeland P, Lin CT.

Mayo Clin Proc. 2019 May;94(5):793-802. doi: 10.1016/j.mayocp.2018.08.036. Epub 2019 Feb 26.


Dose-response associations of cardiorespiratory fitness with all-cause mortality and incidence and mortality of cancer and cardiovascular and respiratory diseases: the UK Biobank cohort study.

Steell L, Ho FK, Sillars A, Petermann-Rocha F, Li H, Lyall DM, Iliodromiti S, Welsh P, Anderson J, MacKay DF, Pell JP, Sattar N, Gill JM, Gray SR, Celis-Morales CA.

Br J Sports Med. 2019 Nov;53(21):1371-1378. doi: 10.1136/bjsports-2018-099093. Epub 2019 Feb 22.


Identification of novel genome-wide associations for suicidality in UK Biobank, genetic correlation with psychiatric disorders and polygenic association with completed suicide.

Strawbridge RJ, Ward J, Ferguson A, Graham N, Shaw RJ, Cullen B, Pearsall R, Lyall LM, Johnston KJA, Niedzwiedz CL, Pell JP, Mackay D, Martin JL, Lyall DM, Bailey MES, Smith DJ.

EBioMedicine. 2019 Mar;41:517-525. doi: 10.1016/j.ebiom.2019.02.005. Epub 2019 Feb 8.


The lifetime prevalence of hospitalised head injury in Scottish prisons: A population study.

McMillan TM, Graham L, Pell JP, McConnachie A, Mackay DF.

PLoS One. 2019 Jan 17;14(1):e0210427. doi: 10.1371/journal.pone.0210427. eCollection 2019.


An evaluation of the effects of lowering blood alcohol concentration limits for drivers on the rates of road traffic accidents and alcohol consumption: a natural experiment.

Haghpanahan H, Lewsey J, Mackay DF, McIntosh E, Pell J, Jones A, Fitzgerald N, Robinson M.

Lancet. 2019 Jan 26;393(10169):321-329. doi: 10.1016/S0140-6736(18)32850-2. Epub 2018 Dec 12.


The RNA-binding proteins Zfp36l1 and Zfp36l2 act redundantly in myogenesis.

Bye-A-Jee H, Pugazhendhi D, Woodhouse S, Brien P, Watson R, Turner M, Pell J.

Skelet Muscle. 2018 Dec 7;8(1):37. doi: 10.1186/s13395-018-0183-9.


The effect of socioeconomic deprivation on the association between an extended measurement of unhealthy lifestyle factors and health outcomes: a prospective analysis of the UK Biobank cohort.

Foster HME, Celis-Morales CA, Nicholl BI, Petermann-Rocha F, Pell JP, Gill JMR, O'Donnell CA, Mair FS.

Lancet Public Health. 2018 Dec;3(12):e576-e585. doi: 10.1016/S2468-2667(18)30200-7. Epub 2018 Nov 20.


Trial protocol: a multicentre randomised trial of first-line treatment pathways for newly diagnosed immune thrombocytopenia: standard steroid treatment versus combined steroid and mycophenolate. The FLIGHT trial.

Pell J, Greenwood R, Ingram J, Wale K, Thomas I, Kandiyali R, Mumford A, Dick A, Bagot C, Cooper N, Hill Q, Bradbury CA.

BMJ Open. 2018 Oct 18;8(10):e024427. doi: 10.1136/bmjopen-2018-024427.


Walking Pace Is Associated with Lower Risk of All-Cause and Cause-Specific Mortality.

Celis-Morales CA, Gray S, Petermann F, Iliodromiti S, Welsh P, Lyall DM, Anderson J, Pellicori P, Mackay DF, Pell JP, Sattar N, Gill JMR.

Med Sci Sports Exerc. 2019 Mar;51(3):472-480. doi: 10.1249/MSS.0000000000001795.


Associations of dietary protein intake with bone mineral density: An observational study in 70,215 UK Biobank participants.

Steell L, Sillars A, Welsh P, Iliodromiti S, Wong SC, Pell JP, Sattar N, Gill JMR, Celis-Morales CA, Gray SR.

Bone. 2019 Mar;120:38-43. doi: 10.1016/j.bone.2018.10.003. Epub 2018 Oct 4.


The association between driving time and unhealthy lifestyles: a cross-sectional, general population study of 386 493 UK Biobank participants.

Mackay A, Mackay DF, Celis-Morales CA, Lyall DM, Gray SR, Sattar N, Gill JMR, Pell JP, Anderson JJ.

J Public Health (Oxf). 2019 Sep 30;41(3):527-534. doi: 10.1093/pubmed/fdy155.


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