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Items: 1 to 50 of 125

1.

Importance of early immune recovery after autologous hematopoietic cell transplantation in lymphoma patients.

Jantunen E, Varmavuo V, Pelkonen J, Valtola J.

Leuk Lymphoma. 2019 Sep;60(9):2115-2121. doi: 10.1080/10428194.2019.1581929. Epub 2019 Mar 7.

PMID:
30843749
2.

Mast Cells Are a Marked Source for Complement C3 Products That Associate with Increased CD11b-Positive Cells in Keratinocyte Skin Carcinomas.

Rahkola D, Laitala J, Siiskonen H, Pelkonen J, Harvima IT.

Cancer Invest. 2019;37(2):73-84. doi: 10.1080/07357907.2019.1565765. Epub 2019 Jan 28.

PMID:
30689427
3.

Comparison of filgrastim, pegfilgrastim, and lipegfilgrastim added to chemotherapy for mobilization of CD34+ cells in non-Hodgkin lymphoma patients.

Partanen A, Valtola J, Ropponen A, Kuitunen H, Kuittinen O, Vasala K, Ågren L, Penttilä K, Keskinen L, Pyörälä M, Nousiainen T, Selander T, Mäntymaa P, Pelkonen J, Varmavuo V, Jantunen E.

Transfusion. 2019 Jan;59(1):325-334. doi: 10.1111/trf.14993. Epub 2018 Nov 19.

PMID:
30450652
4.

Blood graft composition and post-transplant recovery in myeloma patients mobilized with plerixafor: a prospective multicenter study.

Valtola J, Silvennoinen R, Ropponen A, Siitonen T, Säily M, Sankelo M, Putkonen M, Partanen A, Pyörälä M, Savolainen ER, Mäntymaa P, Pelkonen J, Jantunen E, Varmavuo V.

Leuk Lymphoma. 2019 Feb;60(2):453-461. doi: 10.1080/10428194.2018.1485911. Epub 2018 Aug 30.

PMID:
30160591
5.

The combination of TRAIL and MG-132 induces apoptosis in both TRAIL-sensitive and TRAIL-resistant human follicular lymphoma cells.

Adem J, Eray M, Eeva J, Nuutinen U, Pelkonen J.

Leuk Res. 2018 Mar;66:57-65. doi: 10.1016/j.leukres.2018.01.015. Epub 2018 Feb 3.

PMID:
29407584
6.

Immunoreactivity to CYP24A1, but not vitamin D receptor, is increased in mast cells of keratinocyte skin cancers.

Kaukinen A, Siiskonen H, Pelkonen J, Harvima IT.

Eur J Dermatol. 2017 Dec 1;27(6):590-598. doi: 10.1684/ejd.2017.3132.

PMID:
29165303
7.

Preemptive plerixafor injection added to pegfilgrastim after chemotherapy in non-Hodgkin lymphoma patients mobilizing poorly.

Partanen A, Valtola J, Ropponen A, Vasala K, Penttilä K, Ågren L, Pyörälä M, Nousiainen T, Selander T, Mäntymaa P, Pelkonen J, Varmavuo V, Jantunen E.

Ann Hematol. 2017 Nov;96(11):1897-1906. doi: 10.1007/s00277-017-3123-6. Epub 2017 Sep 7.

PMID:
28879595
8.

Impact of lenalidomide-based induction therapy on the mobilization of CD34+ cells, blood graft cellular composition, and post-transplant recovery in myeloma patients: a prospective multicenter study.

Partanen A, Valtola J, Silvennoinen R, Ropponen A, Siitonen T, Putkonen M, Sankelo M, Pelkonen J, Mäntymaa P, Varmavuo V, Jantunen E.

Transfusion. 2017 Oct;57(10):2366-2372. doi: 10.1111/trf.14220. Epub 2017 Jul 5.

PMID:
28681435
9.

Advantages of targeting B cell receptor complex to treat B-cell derived autoimmune diseases and lymphomas.

Adem J, Eray M, Eeva J, Nuutinen U, Pelkonen J.

Mol Immunol. 2017 Aug;88:135-137. doi: 10.1016/j.molimm.2017.05.023. Epub 2017 Jun 20.

PMID:
28644972
10.

RIP1 has a role in CD40-mediated apoptosis in human follicular lymphoma cells.

Adem J, Eray M, Eeva J, Nuutinen U, Pelkonen J.

Immunobiology. 2017 Nov;222(11):998-1003. doi: 10.1016/j.imbio.2017.06.001. Epub 2017 Jun 10.

PMID:
28610909
11.

CD40 Ligand Is Increased in Mast Cells in Psoriasis and Actinic Keratosis but Less So in Epithelial Skin Carcinomas.

Haimakainen S, Kaukinen AP, Suttle MM, Pelkonen J, Harvima IT.

Cancer Invest. 2017 Mar 16;35(3):143-151. doi: 10.1080/07357907.2017.1289216. Epub 2017 Mar 7.

PMID:
28267402
12.

Timing determines dexamethasone and rituximab induced synergistic cell death.

Adem J, Eray M, Eeva J, Nuutinen U, Pelkonen J.

Mol Immunol. 2016 Jul;75:200-2. doi: 10.1016/j.molimm.2016.05.021. Epub 2016 Jun 8.

PMID:
27290654
13.

Blood graft cellular composition and posttransplant outcomes in myeloma patients mobilized with or without low-dose cyclophosphamide: a randomized comparison.

Valtola J, Silvennoinen R, Ropponen A, Siitonen T, Säily M, Sankelo M, Terävä V, Putkonen M, Kuittinen T, Pelkonen J, Mäntymaa P, Remes K, Varmavuo V, Jantunen E.

Transfusion. 2016 Jun;56(6):1394-401. doi: 10.1111/trf.13574. Epub 2016 Apr 4.

PMID:
27041692
14.

Early immune recovery after autologous transplantation in non-Hodgkin lymphoma patients: predictive factors and clinical significance.

Valtola J, Varmavuo V, Ropponen A, Selander T, Kuittinen O, Kuitunen H, Keskinen L, Vasala K, Nousiainen T, Mäntymaa P, Pelkonen J, Jantunen E.

Leuk Lymphoma. 2016 Sep;57(9):2025-32. doi: 10.3109/10428194.2015.1129537. Epub 2016 Jan 14.

PMID:
26763346
15.

Differential Expression of Bcl-2 Family Proteins Determines the Sensitivity of Human Follicular Lymphoma Cells to Dexamethasone-mediated and Anti-BCR-mediated Apoptosis.

Adem J, Ropponen A, Eeva J, Eray M, Nuutinen U, Pelkonen J.

J Immunother. 2016 Jan;39(1):8-14. doi: 10.1097/CJI.0000000000000102.

PMID:
26641257
16.

Mast cells express CYP27A1 and CYP27B1 in epithelial skin cancers and psoriasis.

Kaukinen A, Pelkonen J, Harvima IT.

Eur J Dermatol. 2015 Nov-Dec;25(6):548-55. doi: 10.1684/ejd.2015.2645.

PMID:
26463745
17.

ERK1/2 has an essential role in B cell receptor- and CD40-induced signaling in an in vitro model of germinal center B cell selection.

Adem J, Hämäläinen A, Ropponen A, Eeva J, Eray M, Nuutinen U, Pelkonen J.

Mol Immunol. 2015 Oct;67(2 Pt B):240-7. doi: 10.1016/j.molimm.2015.05.017. Epub 2015 Jun 6.

PMID:
26054744
18.

Blood graft cellular composition and posttransplant recovery in non-Hodgkin's lymphoma patients mobilized with or without plerixafor: a prospective comparison.

Valtola J, Varmavuo V, Ropponen A, Nihtinen A, Partanen A, Vasala K, Lehtonen P, Penttilä K, Pyörälä M, Kuittinen T, Silvennoinen R, Nousiainen T, Pelkonen J, Mäntymaa P, Jantunen E.

Transfusion. 2015 Oct;55(10):2358-68. doi: 10.1111/trf.13170. Epub 2015 May 28.

PMID:
26018461
19.

Rituximab-induced early and late signaling have opposite effects on dexamethasone-induced apoptosis in human follicular lymphoma cells.

Adem J, Ropponen A, Eeva J, Eray M, Pelkonen J, Nuutinen U.

Leuk Lymphoma. 2015;56(8):2448-57. doi: 10.3109/10428194.2014.1001983. Epub 2015 Feb 24.

PMID:
25563557
20.

Blood MxA protein as a marker for respiratory virus infections in young children.

Toivonen L, Schuez-Havupalo L, Rulli M, Ilonen J, Pelkonen J, Melen K, Julkunen I, Peltola V, Waris M.

J Clin Virol. 2015 Jan;62:8-13. doi: 10.1016/j.jcv.2014.11.018. Epub 2014 Nov 18.

PMID:
25542463
21.

Emergence of Klebsiella pneumoniae producing NDM-1 carbapenemase in Saint Petersburg, Russia.

Barantsevich EP, Churkina IV, Barantsevich NE, Pelkonen J, Schlyakhto EV, Woodford N.

J Antimicrob Chemother. 2013 May;68(5):1204-6. doi: 10.1093/jac/dks503. Epub 2013 Jan 12. No abstract available.

PMID:
23315490
22.

Mast cell chymase is present in uterine cervical carcinoma and it detaches viable and growing cervical squamous carcinoma cells from substratum in vitro.

Diaconu NC, Rummukainen J, Naukkarinen A, Mättö M, Harvima RJ, Pelkonen J, Harvima IT.

Arch Dermatol Res. 2011 Sep;303(7):499-512. doi: 10.1007/s00403-011-1121-4. Epub 2011 Jan 29.

PMID:
21274549
23.

Feedback regulation of mitochondria by caspase-9 in the B cell receptor-mediated apoptosis.

Eeva J, Nuutinen U, Ropponen A, Mättö M, Eray M, Pellinen R, Wahlfors J, Pelkonen J.

Scand J Immunol. 2009 Dec;70(6):574-83. doi: 10.1111/j.1365-3083.2009.02331.x.

24.

The effect of microenvironmental CD40 signals on TRAIL- and drug-induced apoptosis in follicular lymphoma cells.

Nuutinen U, Ropponen A, Eeva J, Eray M, Pellinen R, Wahlfors J, Pelkonen J.

Scand J Immunol. 2009 Dec;70(6):565-73. doi: 10.1111/j.1365-3083.2009.02330.x.

25.

Lysosomal-mitochondrial axis in zoledronic acid-induced apoptosis in human follicular lymphoma cells.

Mitrofan LM, Castells FB, Pelkonen J, Mönkkönen J.

J Biol Chem. 2010 Jan 15;285(3):1967-79. doi: 10.1074/jbc.M109.038935. Epub 2009 Oct 29.

26.

The level of ATP analog and isopentenyl pyrophosphate correlates with zoledronic acid-induced apoptosis in cancer cells in vitro.

Mitrofan LM, Pelkonen J, Mönkkönen J.

Bone. 2009 Dec;45(6):1153-60. doi: 10.1016/j.bone.2009.08.010. Epub 2009 Aug 21.

PMID:
19699819
27.

Dexamethasone-induced apoptosis and up-regulation of Bim is dependent on glycogen synthase kinase-3.

Nuutinen U, Ropponen A, Suoranta S, Eeva J, Eray M, Pellinen R, Wahlfors J, Pelkonen J.

Leuk Res. 2009 Dec;33(12):1714-7. doi: 10.1016/j.leukres.2009.06.004. Epub 2009 Jun 25.

PMID:
19559478
28.

Co-cultivated damp building related microbes Streptomyces californicus and Stachybotrys chartarum induce immunotoxic and genotoxic responses via oxidative stress.

Markkanen Penttinen P, Pelkonen J, Tapanainen M, Mäki-Paakkanen J, Jalava PI, Hirvonen MR.

Inhal Toxicol. 2009 Aug;21(10):857-67. doi: 10.1080/08958370802526873.

PMID:
19459771
29.

The involvement of mitochondria and the caspase-9 activation pathway in rituximab-induced apoptosis in FL cells.

Eeva J, Nuutinen U, Ropponen A, Mättö M, Eray M, Pellinen R, Wahlfors J, Pelkonen J.

Apoptosis. 2009 May;14(5):687-98. doi: 10.1007/s10495-009-0337-7.

PMID:
19308735
30.

Regulation of repertoire development through genetic control of DH reading frame preference.

Zemlin M, Schelonka RL, Ippolito GC, Zemlin C, Zhuang Y, Gartland GL, Nitschke L, Pelkonen J, Rajewsky K, Schroeder HW Jr.

J Immunol. 2008 Dec 15;181(12):8416-24.

31.

PDTC enables type I TRAIL signaling in type II follicular lymphoma cells.

Nuutinen U, Simelius N, Ropponen A, Eeva J, Mättö M, Eray M, Pellinen R, Wahlfors J, Pelkonen J.

Leuk Res. 2009 Jun;33(6):829-36. doi: 10.1016/j.leukres.2008.09.025. Epub 2008 Nov 1.

PMID:
18977530
32.

Cervical squamous carcinoma cells are resistant to the combined action of tumor necrosis factor-alpha and histamine whereas normal keratinocytes undergo cytolysis.

Diaconu NC, Rummukainen J, Mättö M, Naukkarinen A, Harvima RJ, Pelkonen J, Harvima IT.

BMC Cancer. 2008 Feb 7;8:46. doi: 10.1186/1471-2407-8-46.

33.

Human B cells and macrophages cooperate in T-cell-independent type 2 response.

Mättö M, Raunio AR, Postila V, Huttunen K, Hirvonen MR, Pelkonen J.

Scand J Immunol. 2008 Mar;67(3):209-17. doi: 10.1111/j.1365-3083.2007.02057.x. Epub 2008 Jan 10.

34.

Transcriptional response of human dendritic cells to Borrelia garinii--defective CD38 and CCR7 expression detected.

Hartiala P, Hytönen J, Pelkonen J, Kimppa K, West A, Penttinen MA, Suhonen J, Lahesmaa R, Viljanen MK.

J Leukoc Biol. 2007 Jul;82(1):33-43. Epub 2007 Apr 17.

PMID:
17440035
35.
36.

DNA damage and p53 in RAW264.7 cells induced by the spores of co-cultivated Streptomyces californicus and Stachybotrys chartarum.

Penttinen P, Tampio M, Mäki-Paakkanen J, Vähäkangas K, Pelkonen J, Hirvonen MR.

Toxicology. 2007 Jun 3;235(1-2):92-102. Epub 2007 Mar 12.

PMID:
17420079
37.

Towards an understanding of apoptosis detection by SYTO dyes.

Wlodkowic D, Skommer J, Pelkonen J.

Cytometry A. 2007 Feb;71(2):61-72.

38.

Gene-expression profiling during curcumin-induced apoptosis reveals downregulation of CXCR4.

Skommer J, Wlodkowic D, Pelkonen J.

Exp Hematol. 2007 Jan;35(1):84-95.

PMID:
17198877
39.

Co-cultivation of Streptomyces californicus and Stachybotrys chartarum stimulates the production of cytostatic compound(s) with immunotoxic properties.

Penttinen P, Pelkonen J, Huttunen K, Hirvonen MR.

Toxicol Appl Pharmacol. 2006 Dec 15;217(3):342-51. Epub 2006 Sep 30.

PMID:
17095029
40.

CXCR4 expression during tumour cell death.

Skommer J, Wlodkowic D, Pelkonen J.

Leuk Res. 2007 Aug;31(8):1155-6. Epub 2006 Oct 24. No abstract available.

PMID:
17064769
41.

The CD40-induced protection against CD95-mediated apoptosis is associated with a rapid upregulation of anti-apoptotic c-FLIP.

Eeva J, Ropponen A, Nuutinen U, Eeva ST, Mättö M, Eray M, Pelkonen J.

Mol Immunol. 2007 Feb;44(6):1230-7. Epub 2006 Aug 9.

PMID:
16901543
42.

Persistent brain infection and disease reactivation in relapsing fever borreliosis.

Larsson C, Andersson M, Pelkonen J, Guo BP, Nordstrand A, Bergström S.

Microbes Infect. 2006 Jul;8(8):2213-9. Epub 2006 May 30.

PMID:
16782384
43.

Forced usage of positively charged amino acids in immunoglobulin CDR-H3 impairs B cell development and antibody production.

Ippolito GC, Schelonka RL, Zemlin M, Ivanov II, Kobayashi R, Zemlin C, Gartland GL, Nitschke L, Pelkonen J, Fujihashi K, Rajewsky K, Schroeder HW Jr.

J Exp Med. 2006 Jun 12;203(6):1567-78. Epub 2006 Jun 5.

44.

hCAR-EGFP fusion receptor in human follicular lymphoma B cells - a model for adenoviral gene therapy for B cell malignancies.

Mättö M, Nuutinen UM, Hakkarainen T, Tallone T, Wahlfors J, Pelkonen J.

Int J Mol Med. 2006 Jun;17(6):1057-62.

PMID:
16685416
45.

Cellular foundation of curcumin-induced apoptosis in follicular lymphoma cell lines.

Skommer J, Wlodkowic D, Pelkonen J.

Exp Hematol. 2006 Apr;34(4):463-74.

PMID:
16569593
46.

Multiparametric analysis of HA14-1-induced apoptosis in follicular lymphoma cells.

Wlodkowic D, Skommer J, Pelkonen J.

Leuk Res. 2006 Sep;30(9):1187-92. Epub 2006 Jan 18.

PMID:
16414117
47.

Inhibition of PI3-kinase-Akt pathway enhances dexamethasone-induced apoptosis in a human follicular lymphoma cell line.

Nuutinen U, Postila V, Mättö M, Eeva J, Ropponen A, Eray M, Riikonen P, Pelkonen J.

Exp Cell Res. 2006 Feb 1;312(3):322-30. Epub 2005 Nov 23.

PMID:
16309671
48.

A single DH gene segment creates its own unique CDR-H3 repertoire and is sufficient for B cell development and immune function.

Schelonka RL, Ivanov II, Jung DH, Ippolito GC, Nitschke L, Zhuang Y, Gartland GL, Pelkonen J, Alt FW, Rajewsky K, Schroeder HW Jr.

J Immunol. 2005 Nov 15;175(10):6624-32.

49.

HA14-1, a small molecule Bcl-2 antagonist, induces apoptosis and modulates action of selected anticancer drugs in follicular lymphoma B cells.

Skommer J, Wlodkowic D, Mättö M, Eray M, Pelkonen J.

Leuk Res. 2006 Mar;30(3):322-31. Epub 2005 Oct 6.

PMID:
16213584
50.

CD45RA and RO isoforms have distinct effects on cytokine- and B-cell-receptor-mediated signalling in human B cells.

Mättö M, Nuutinen UM, Ropponen A, Myllykangas K, Pelkonen J.

Scand J Immunol. 2005 Jun;61(6):520-8.

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