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Items: 28

1.

Quantitative Proteomics and Mechanistic Modeling of Transporter-mediated Disposition in Non-Alcoholic Fatty Liver Disease.

Vildhede A, Kimoto E, Pelis RM, Rodrigues AD, Varma MVS.

Clin Pharmacol Ther. 2019 Oct 20. doi: 10.1002/cpt.1699. [Epub ahead of print]

PMID:
31630405
2.

ClC Channels and Transporters: Structure, Physiological Functions, and Implications in Human Chloride Channelopathies.

Poroca DR, Pelis RM, Chappe VM.

Front Pharmacol. 2017 Mar 23;8:151. doi: 10.3389/fphar.2017.00151. eCollection 2017. Review.

3.

Influence of age on intestinal bile acid transport in C57BL/6 mice.

Gao T, Feridooni HA, Howlett SE, Pelis RM.

Pharmacol Res Perspect. 2017 Feb 3;5(2):e00287. doi: 10.1002/prp2.287. eCollection 2017 Apr.

4.

Drug Transport by the Blood-Aqueous Humor Barrier of the Eye.

Lee J, Pelis RM.

Drug Metab Dispos. 2016 Oct;44(10):1675-81. doi: 10.1124/dmd.116.069369. Epub 2016 Feb 19. Review.

PMID:
26895982
5.

Organic anion transporter 2 transcript variant 1 shows broad ligand selectivity when expressed in multiple cell lines.

Hotchkiss AG, Berrigan L, Pelis RM.

Front Pharmacol. 2015 Oct 6;6:216. doi: 10.3389/fphar.2015.00216. eCollection 2015.

6.

Organic Anion Transporter 1 Is Inhibited by Multiple Mechanisms and Shows a Transport Mode Independent of Exchange.

Hotchkiss AG, Gao T, Khan U, Berrigan L, Li M, Ingraham L, Pelis RM.

Drug Metab Dispos. 2015 Dec;43(12):1847-54. doi: 10.1124/dmd.115.065748. Epub 2015 Sep 14.

PMID:
26370539
7.

A renal-like organic anion transport system in the ciliary epithelium of the bovine and human eye.

Lee J, Shahidullah M, Hotchkiss A, Coca-Prados M, Delamere NA, Pelis RM.

Mol Pharmacol. 2015 Apr;87(4):697-705. doi: 10.1124/mol.114.096578. Epub 2015 Feb 6.

8.

Cystic fibrosis transmembrane conductance regulator dysfunction in VIP knockout mice.

Alcolado NG, Conrad DJ, Poroca D, Li M, Alshafie W, Chappe FG, Pelis RM, Anini Y, Xu Z, Hamidi S, Said SI, Chappe VM.

Am J Physiol Cell Physiol. 2014 Jul 15;307(2):C195-207. doi: 10.1152/ajpcell.00293.2013. Epub 2014 Jun 4.

9.

A plasma concentration of α-ketoglutarate influences the kinetic interaction of ligands with organic anion transporter 1.

Ingraham L, Li M, Renfro JL, Parker S, Vapurcuyan A, Hanna I, Pelis RM.

Mol Pharmacol. 2014 Jul;86(1):86-95. doi: 10.1124/mol.114.091777. Epub 2014 Apr 25.

PMID:
24770989
10.

SLC22, SLC44, and SLC47 transporters--organic anion and cation transporters: molecular and cellular properties.

Pelis RM, Wright SH.

Curr Top Membr. 2014;73:233-61. doi: 10.1016/B978-0-12-800223-0.00006-2. Review.

PMID:
24745985
11.

Functional significance of conserved cysteines in the human organic cation transporter 2.

Pelis RM, Dangprapai Y, Cheng Y, Zhang X, Terpstra J, Wright SH.

Am J Physiol Renal Physiol. 2012 Jul 15;303(2):F313-20. doi: 10.1152/ajprenal.00038.2012. Epub 2012 May 9.

12.

Expression of organic anion transporter 2 in the human kidney and its potential role in the tubular secretion of guanine-containing antiviral drugs.

Cheng Y, Vapurcuyan A, Shahidullah M, Aleksunes LM, Pelis RM.

Drug Metab Dispos. 2012 Mar;40(3):617-24. doi: 10.1124/dmd.111.042036. Epub 2011 Dec 21.

PMID:
22190696
13.

Renal transport of organic anions and cations.

Pelis RM, Wright SH.

Compr Physiol. 2011 Oct;1(4):1795-835. doi: 10.1002/cphy.c100084. Review.

PMID:
23733689
14.

Differences in the substrate binding regions of renal organic anion transporters 1 (OAT1) and 3 (OAT3).

Astorga B, Wunz TM, Morales M, Wright SH, Pelis RM.

Am J Physiol Renal Physiol. 2011 Aug;301(2):F378-86. doi: 10.1152/ajprenal.00735.2010. Epub 2011 May 4.

15.

Localization of multidrug resistance-associated protein 2 in the nonpigmented ciliary epithelium of the eye.

Pelis RM, Shahidullah M, Ghosh S, Coca-Prados M, Wright SH, Delamere NA.

J Pharmacol Exp Ther. 2009 May;329(2):479-85. doi: 10.1124/jpet.108.149625. Epub 2009 Feb 6.

16.

Studies on bicarbonate transporters and carbonic anhydrase in porcine nonpigmented ciliary epithelium.

Shahidullah M, To CH, Pelis RM, Delamere NA.

Invest Ophthalmol Vis Sci. 2009 Apr;50(4):1791-800. doi: 10.1167/iovs.08-2487. Epub 2008 Nov 14.

17.

Influence of estrogen and xenoestrogens on basolateral uptake of tetraethylammonium by opossum kidney cells in culture.

Pelis RM, Hartman RC, Wright SH, Wunz TM, Groves CE.

J Pharmacol Exp Ther. 2007 Nov;323(2):555-61. Epub 2007 Aug 7.

PMID:
17684116
18.

Inorganic mercury interacts with cysteine residues (C451 and C474) of hOCT2 to reduce its transport activity.

Pelis RM, Dangprapai Y, Wunz TM, Wright SH.

Am J Physiol Renal Physiol. 2007 May;292(5):F1583-91. Epub 2007 Feb 6.

19.

Cysteine accessibility in the hydrophilic cleft of human organic cation transporter 2.

Pelis RM, Zhang X, Dangprapai Y, Wright SH.

J Biol Chem. 2006 Nov 17;281(46):35272-80. Epub 2006 Sep 21.

20.

Functional influence of N-glycosylation in OCT2-mediated tetraethylammonium transport.

Pelis RM, Suhre WM, Wright SH.

Am J Physiol Renal Physiol. 2006 May;290(5):F1118-26. Epub 2005 Dec 20.

21.

Transepithelial urate transport by avian renal proximal tubule epithelium in primary culture.

Dudas PL, Pelis RM, Braun EJ, Renfro JL.

J Exp Biol. 2005 Nov;208(Pt 22):4305-15.

22.

Stimulation of renal sulfate secretion by metabolic acidosis requires Na+/H+ exchange induction and carbonic anhydrase.

Pelis RM, Edwards SL, Kunigelis SC, Claiborne JB, Renfro JL.

Am J Physiol Renal Physiol. 2005 Jul;289(1):F208-16. Epub 2005 Mar 1.

23.

Cortisol receptor blockade and seawater adaptation in the euryhaline teleost Fundulus heteroclitus.

Marshall WS, Cozzi RR, Pelis RM, McCormick SD.

J Exp Zool A Comp Exp Biol. 2005 Feb 1;303(2):132-42.

PMID:
15662660
24.

Role of tubular secretion and carbonic anhydrase in vertebrate renal sulfate excretion.

Pelis RM, Renfro JL.

Am J Physiol Regul Integr Comp Physiol. 2004 Sep;287(3):R491-501. Review.

25.

Cortisol alters carbonic anhydrase-mediated renal sulfate secretion.

Pelis RM, Goldmeyer JE, Crivello J, Renfro JL.

Am J Physiol Regul Integr Comp Physiol. 2003 Dec;285(6):R1430-8. Epub 2003 Aug 7.

26.

Active sulfate secretion by the intestine of winter flounder is through exchange for luminal chloride.

Pelis RM, Renfro JL.

Am J Physiol Regul Integr Comp Physiol. 2003 Feb;284(2):R380-8. Epub 2002 Oct 17.

27.
28.

Gill Na(+)-K(+)-2Cl(-) cotransporter abundance and location in Atlantic salmon: effects of seawater and smolting.

Pelis RM, Zydlewski J, McCormick SD.

Am J Physiol Regul Integr Comp Physiol. 2001 Jun;280(6):R1844-52.

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