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Items: 1 to 50 of 442

1.

Nanoscale Distribution of Nuclear Sites by Super-Resolved Image Cross-Correlation Spectroscopy.

Oneto M, Scipioni L, Sarmento MJ, Cainero I, Pelicci S, Furia L, Pelicci PG, Dellino GI, Bianchini P, Faretta M, Gratton E, Diaspro A, Lanzanò L.

Biophys J. 2019 Nov 2. pii: S0006-3495(19)30898-7. doi: 10.1016/j.bpj.2019.10.036. [Epub ahead of print]

2.

Correction: Dual role for miR-34a in the control of early progenitor proliferation and commitment in the mammary gland and in breast cancer.

Bonetti P, Climent M, Panebianco F, Tordonato C, Santoro A, Marzi MJ, Pelicci PG, Ventura A, Nicassio F.

Oncogene. 2019 Nov 8. doi: 10.1038/s41388-019-1094-x. [Epub ahead of print]

PMID:
31705063
3.

Human cord blood (hCB)-CD34+ humanized mice fail to reject human acute myeloid leukemia cells.

Tanaskovic O, Verga Falzacappa MV, Pelicci PG.

PLoS One. 2019 Sep 19;14(9):e0217345. doi: 10.1371/journal.pone.0217345. eCollection 2019.

4.

Obesity is a risk factor for acute promyelocytic leukemia: evidence from population and cross-sectional studies studies and correlation with flt3 mutations and polyunsaturated fatty acid metabolism.

Mazzarella L, Botteri E, Matthews A, Gatti E, Di Salvatore D, Bagnardi V, Breccia M, Montesinos P, Bernal T, Gil C, Ley TJ, Sanz M, Bhaskaran K, Lo Coco F, Pelicci PG.

Haematologica. 2019 Sep 12. pii: haematol.2019.223925. doi: 10.3324/haematol.2019.223925. [Epub ahead of print]

5.

Emerging roles of HECT-type E3 ubiquitin ligases in autophagy regulation.

Melino G, Cecconi F, Pelicci PG, Mak TW, Bernassola F.

Mol Oncol. 2019 Oct;13(10):2033-2048. doi: 10.1002/1878-0261.12567. Epub 2019 Sep 5. Review.

6.

Correction for Danovi et al., "Amplification of Mdmx (or Mdm4) Directly Contributes to Tumor Formation by Inhibiting p53 Tumor Suppressor Activity".

Danovi D, Meulmeester E, Pasini D, Migliorini D, Capra M, Frenk R, de Graaf P, Francoz S, Gasparini P, Gobbi A, Helin K, Pelicci PG, Jochemsen AG, Marine JC.

Mol Cell Biol. 2019 Jul 16;39(15). pii: e00150-19. doi: 10.1128/MCB.00150-19. Print 2019 Aug 1. No abstract available.

7.

Tumor mutational burden quantification from targeted gene panels: major advancements and challenges.

Fancello L, Gandini S, Pelicci PG, Mazzarella L.

J Immunother Cancer. 2019 Jul 15;7(1):183. doi: 10.1186/s40425-019-0647-4. Review.

8.

Development of Personalized Therapeutic Strategies by Targeting Actionable Vulnerabilities in Metastatic and Chemotherapy-Resistant Breast Cancer PDXs.

Punzi S, Meliksetian M, Riva L, Marocchi F, Pruneri G, Criscitiello C, Orsi F, Spaggiari L, Casiraghi M, Della Vigna P, Luzi L, Curigliano G, Pelicci PG, Lanfrancone L.

Cells. 2019 Jun 18;8(6). pii: E605. doi: 10.3390/cells8060605.

9.

Release of paused RNA polymerase II at specific loci favors DNA double-strand-break formation and promotes cancer translocations.

Dellino GI, Palluzzi F, Chiariello AM, Piccioni R, Bianco S, Furia L, De Conti G, Bouwman BAM, Melloni G, Guido D, Giacò L, Luzi L, Cittaro D, Faretta M, Nicodemi M, Crosetto N, Pelicci PG.

Nat Genet. 2019 Jun;51(6):1011-1023. doi: 10.1038/s41588-019-0421-z. Epub 2019 May 20.

PMID:
31110352
10.

Combination of Hypoglycemia and Metformin Impairs Tumor Metabolic Plasticity and Growth by Modulating the PP2A-GSK3β-MCL-1 Axis.

Elgendy M, Cirò M, Hosseini A, Weiszmann J, Mazzarella L, Ferrari E, Cazzoli R, Curigliano G, DeCensi A, Bonanni B, Budillon A, Pelicci PG, Janssens V, Ogris M, Baccarini M, Lanfrancone L, Weckwerth W, Foiani M, Minucci S.

Cancer Cell. 2019 May 13;35(5):798-815.e5. doi: 10.1016/j.ccell.2019.03.007. Epub 2019 Apr 25.

PMID:
31031016
11.

p66Shc deficiency in the Eμ-TCL1 mouse model of chronic lymphocytic leukemia enhances leukemogenesis by altering the chemokine receptor landscape.

Patrussi L, Capitani N, Ulivieri C, Manganaro N, Granai M, Cattaneo F, Kabanova A, Mundo L, Gobessi S, Frezzato F, Visentin A, Finetti F, Pelicci PG, D'Elios MM, Trentin L, Semenzato G, Leoncini L, Efremov DG, Baldari CT.

Haematologica. 2019 Oct;104(10):2040-2052. doi: 10.3324/haematol.2018.209981. Epub 2019 Feb 28.

12.

Modeling cell proliferation in human acute myeloid leukemia xenografts.

Nobile MS, Vlachou T, Spolaor S, Bossi D, Cazzaniga P, Lanfrancone L, Mauri G, Pelicci PG, Besozzi D.

Bioinformatics. 2019 Sep 15;35(18):3378-3386. doi: 10.1093/bioinformatics/btz063.

13.

p53 Loss in Breast Cancer Leads to Myc Activation, Increased Cell Plasticity, and Expression of a Mitotic Signature with Prognostic Value.

Santoro A, Vlachou T, Luzi L, Melloni G, Mazzarella L, D'Elia E, Aobuli X, Pasi CE, Reavie L, Bonetti P, Punzi S, Casoli L, Sabò A, Moroni MC, Dellino GI, Amati B, Nicassio F, Lanfrancone L, Pelicci PG.

Cell Rep. 2019 Jan 15;26(3):624-638.e8. doi: 10.1016/j.celrep.2018.12.071.

14.

ΔNp63 promotes IGF1 signalling through IRS1 in squamous cell carcinoma.

Frezza V, Fierro C, Gatti E, Peschiaroli A, Lena AM, Petruzzelli MA, Candi E, Anemona L, Mauriello A, Pelicci PG, Melino G, Bernassola F.

Aging (Albany NY). 2018 Dec 28;10(12):4224-4240. doi: 10.18632/aging.101725.

15.

Genome-wide mapping of 8-oxo-7,8-dihydro-2'-deoxyguanosine reveals accumulation of oxidatively-generated damage at DNA replication origins within transcribed long genes of mammalian cells.

Amente S, Di Palo G, Scala G, Castrignanò T, Gorini F, Cocozza S, Moresano A, Pucci P, Ma B, Stepanov I, Lania L, Pelicci PG, Dellino GI, Majello B.

Nucleic Acids Res. 2019 Jan 10;47(1):221-236. doi: 10.1093/nar/gky1152.

16.

Epigenomic profiling of archived FFPE tissues by enhanced PAT-ChIP (EPAT-ChIP) technology.

Amatori S, Persico G, Paolicelli C, Hillje R, Sahnane N, Corini F, Furlan D, Luzi L, Minucci S, Giorgio M, Pelicci PG, Fanelli M.

Clin Epigenetics. 2018 Nov 16;10(1):143. doi: 10.1186/s13148-018-0576-y.

17.

Activated protein C reverses epigenetically sustained p66Shc expression in plaque-associated macrophages in diabetes.

Shahzad K, Gadi I, Nazir S, Al-Dabet MM, Kohli S, Bock F, Breitenstein L, Ranjan S, Fuchs T, Halloul Z, Nawroth PP, Pelicci PG, Braun-Dullaeus RC, Camerer E, Esmon CT, Isermann B.

Commun Biol. 2018 Aug 6;1:104. doi: 10.1038/s42003-018-0108-5. eCollection 2018.

18.

European Academy of Cancer Sciences - position paper.

Adami HO, Berns A, Celis JE, de Vries E, Eggermont A, Harris A, Zur Hausen H, Pelicci PG, Ringborg U.

Mol Oncol. 2018 Nov;12(11):1829-1837. doi: 10.1002/1878-0261.12379. Epub 2018 Sep 21.

19.

Aging phenotype(s) in kidneys of diabetic mice are p66ShcA dependent.

Vashistha H, Marrero L, Reiss K, Cohen AJ, Malhotra A, Javed T, Bradley A, Abbruscato F, Giusti S, Jimenez A, Mehra S, Kaushal D, Giorgio M, Pelicci PG, Kakoki M, Singhal PC, Bunnell B, Meggs LG.

Am J Physiol Renal Physiol. 2018 Dec 1;315(6):F1833-F1842. doi: 10.1152/ajprenal.00608.2017. Epub 2018 Sep 12.

PMID:
30207172
20.

Exploiting the tunability of stimulated emission depletion microscopy for super-resolution imaging of nuclear structures.

Sarmento MJ, Oneto M, Pelicci S, Pesce L, Scipioni L, Faretta M, Furia L, Dellino GI, Pelicci PG, Bianchini P, Diaspro A, Lanzanò L.

Nat Commun. 2018 Aug 24;9(1):3415. doi: 10.1038/s41467-018-05963-2.

21.

The pro-oxidant adaptor p66SHC promotes B cell mitophagy by disrupting mitochondrial integrity and recruiting LC3-II.

Onnis A, Cianfanelli V, Cassioli C, Samardzic D, Pelicci PG, Cecconi F, Baldari CT.

Autophagy. 2018;14(12):2117-2138. doi: 10.1080/15548627.2018.1505153. Epub 2018 Sep 6.

PMID:
30109811
22.

Dual role for miR-34a in the control of early progenitor proliferation and commitment in the mammary gland and in breast cancer.

Bonetti P, Climent M, Panebianco F, Tordonato C, Santoro A, Marzi MJ, Pelicci PG, Ventura A, Nicassio F.

Oncogene. 2019 Jan;38(3):360-374. doi: 10.1038/s41388-018-0445-3. Epub 2018 Aug 9. Erratum in: Oncogene. 2019 Nov 8;:.

23.

Targeting WEE1 to enhance conventional therapies for acute lymphoblastic leukemia.

Ghelli Luserna Di Rorà A, Beeharry N, Imbrogno E, Ferrari A, Robustelli V, Righi S, Sabattini E, Verga Falzacappa MV, Ronchini C, Testoni N, Baldazzi C, Papayannidis C, Abbenante MC, Marconi G, Paolini S, Parisi S, Sartor C, Fontana MC, De Matteis S, Iacobucci I, Pelicci PG, Cavo M, Yen TJ, Martinelli G.

J Hematol Oncol. 2018 Aug 1;11(1):99. doi: 10.1186/s13045-018-0641-1.

24.

PREP1 tumor suppressor protects the late-replicating DNA by controlling its replication timing and symmetry.

Palmigiano A, Santaniello F, Cerutti A, Penkov D, Purushothaman D, Makhija E, Luzi L, di Fagagna FD, Pelicci PG, Shivashankar V, Dellino GI, Blasi F.

Sci Rep. 2018 Feb 16;8(1):3198. doi: 10.1038/s41598-018-21363-4.

25.

p66Shc deficiency enhances CXCR4 and CCR7 recycling in CLL B cells by facilitating their dephosphorylation-dependent release from β-arrestin at early endosomes.

Patrussi L, Capitani N, Cattaneo F, Manganaro N, Gamberucci A, Frezzato F, Martini V, Visentin A, Pelicci PG, D'Elios MM, Trentin L, Semenzato G, Baldari CT.

Oncogene. 2018 Mar;37(11):1534-1550. doi: 10.1038/s41388-017-0066-2. Epub 2018 Jan 12.

PMID:
29326436
26.

The E3 ubiquitin ligase WWP1 sustains the growth of acute myeloid leukaemia.

Sanarico AG, Ronchini C, Croce A, Memmi EM, Cammarata UA, De Antoni A, Lavorgna S, Divona M, Giacò L, Melloni GEM, Brendolan A, Simonetti G, Martinelli G, Mancuso P, Bertolini F, Coco FL, Melino G, Pelicci PG, Bernassola F.

Leukemia. 2018 Apr;32(4):911-919. doi: 10.1038/leu.2017.342. Epub 2017 Dec 6.

27.

Tumour-derived PGD2 and NKp30-B7H6 engagement drives an immunosuppressive ILC2-MDSC axis.

Trabanelli S, Chevalier MF, Martinez-Usatorre A, Gomez-Cadena A, Salomé B, Lecciso M, Salvestrini V, Verdeil G, Racle J, Papayannidis C, Morita H, Pizzitola I, Grandclément C, Bohner P, Bruni E, Girotra M, Pallavi R, Falvo P, Leibundgut EO, Baerlocher GM, Carlo-Stella C, Taurino D, Santoro A, Spinelli O, Rambaldi A, Giarin E, Basso G, Tresoldi C, Ciceri F, Gfeller D, Akdis CA, Mazzarella L, Minucci S, Pelicci PG, Marcenaro E, McKenzie ANJ, Vanhecke D, Coukos G, Mavilio D, Curti A, Derré L, Jandus C.

Nat Commun. 2017 Sep 19;8(1):593. doi: 10.1038/s41467-017-00678-2.

28.

Interrogating open issues in cancer medicine with patient-derived xenografts.

Byrne AT, Alférez DG, Amant F, Annibali D, Arribas J, Biankin AV, Bruna A, Budinská E, Caldas C, Chang DK, Clarke RB, Clevers H, Coukos G, Dangles-Marie V, Eckhardt SG, Gonzalez-Suarez E, Hermans E, Hidalgo M, Jarzabek MA, de Jong S, Jonkers J, Kemper K, Lanfrancone L, Mælandsmo GM, Marangoni E, Marine JC, Medico E, Norum JH, Palmer HG, Peeper DS, Pelicci PG, Piris-Gimenez A, Roman-Roman S, Rueda OM, Seoane J, Serra V, Soucek L, Vanhecke D, Villanueva A, Vinolo E, Bertotti A, Trusolino L.

Nat Rev Cancer. 2017 Sep 15;17(10):632. doi: 10.1038/nrc.2017.85. [Epub ahead of print]

PMID:
28912576
29.

Glucose and Lactate Miniaturized Biosensors for SECM-Based High-Spatial Resolution Analysis: A Comparative Study.

Soldà A, Valenti G, Marcaccio M, Giorgio M, Pelicci PG, Paolucci F, Rapino S.

ACS Sens. 2017 Sep 22;2(9):1310-1318. doi: 10.1021/acssensors.7b00324. Epub 2017 Aug 24.

PMID:
28836760
30.

Mutations targeting the coagulation pathway are enriched in brain metastases.

Richichi C, Fornasari L, Melloni GEM, Brescia P, Patanè M, Del Bene M, Mustafa DAM, Kros JM, Pollo B, Pruneri G, Sciandivasci A, Munzone E, DiMeco F, Pelicci PG, Riva L, Pelicci G.

Sci Rep. 2017 Jul 26;7(1):6573. doi: 10.1038/s41598-017-06811-x.

31.

Transcriptional activation of RagD GTPase controls mTORC1 and promotes cancer growth.

Di Malta C, Siciliano D, Calcagni A, Monfregola J, Punzi S, Pastore N, Eastes AN, Davis O, De Cegli R, Zampelli A, Di Giovannantonio LG, Nusco E, Platt N, Guida A, Ogmundsdottir MH, Lanfrancone L, Perera RM, Zoncu R, Pelicci PG, Settembre C, Ballabio A.

Science. 2017 Jun 16;356(6343):1188-1192. doi: 10.1126/science.aag2553.

32.

A harmonized and efficient clinical research environment would benefit patients and enhance European competitiveness. Commentary.

Amato A, Aringhieri E, Boccia S, Buccella F, Gorini B, Gramaglia D, Masetti R, Rossi P, Pelicci PG.

Ann Ist Super Sanita. 2017 Apr-Jun;53(2):104-107. doi: 10.4415/ANN_17_02_05.

33.

A knowledge-based framework for the discovery of cancer-predisposing variants using large-scale sequencing breast cancer data.

Melloni GEM, Mazzarella L, Bernard L, Bodini M, Russo A, Luzi L, Pelicci PG, Riva L.

Breast Cancer Res. 2017 May 31;19(1):63. doi: 10.1186/s13058-017-0854-1.

34.

Interrogating open issues in cancer precision medicine with patient-derived xenografts.

Byrne AT, Alférez DG, Amant F, Annibali D, Arribas J, Biankin AV, Bruna A, Budinská E, Caldas C, Chang DK, Clarke RB, Clevers H, Coukos G, Dangles-Marie V, Eckhardt SG, Gonzalez-Suarez E, Hermans E, Hidalgo M, Jarzabek MA, de Jong S, Jonkers J, Kemper K, Lanfrancone L, Mælandsmo GM, Marangoni E, Marine JC, Medico E, Norum JH, Palmer HG, Peeper DS, Pelicci PG, Piris-Gimenez A, Roman-Roman S, Rueda OM, Seoane J, Serra V, Soucek L, Vanhecke D, Villanueva A, Vinolo E, Bertotti A, Trusolino L.

Nat Rev Cancer. 2017 Apr;17(4):254-268. doi: 10.1038/nrc.2016.140. Epub 2017 Jan 20. Review. Erratum in: Nat Rev Cancer. 2017 Sep 15;:.

35.

PML-RARA-associated cooperating mutations belong to a transcriptional network that is deregulated in myeloid leukemias.

Ronchini C, Brozzi A, Riva L, Luzi L, Gruszka AM, Melloni GEM, Scanziani E, Dharmalingam G, Mutarelli M, Belcastro V, Lavorgna S, Rossi V, Spinelli O, Biondi A, Rambaldi A, Lo-Coco F, di Bernardo D, Pelicci PG.

Leukemia. 2017 Sep;31(9):1975-1986. doi: 10.1038/leu.2016.386. Epub 2016 Dec 27.

PMID:
28025581
36.

miR-494-3p is a novel tumor driver of lung carcinogenesis.

Faversani A, Amatori S, Augello C, Colombo F, Porretti L, Fanelli M, Ferrero S, Palleschi A, Pelicci PG, Belloni E, Ercoli G, Degrassi A, Baccarin M, Altieri DC, Vaira V, Bosari S.

Oncotarget. 2017 Jan 31;8(5):7231-7247. doi: 10.18632/oncotarget.13933.

37.

From the maximum tolerable to the minimum effective treatment: The Umberto Veronesi's life commitment to breast cancer care.

Curigliano G, Cardoso F, Costa A, Galimberti V, Goldhirsch A, Pelicci PG, Veronesi P, Viale G, Orecchia R.

Breast. 2017 Feb;31:241-243. doi: 10.1016/j.breast.2016.11.013. Epub 2016 Nov 19. No abstract available.

PMID:
27876474
38.

Molecular mechanisms of asymmetric divisions in mammary stem cells.

Santoro A, Vlachou T, Carminati M, Pelicci PG, Mapelli M.

EMBO Rep. 2016 Dec;17(12):1700-1720. Epub 2016 Nov 21. Review.

39.

The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery.

Stunnenberg HG; International Human Epigenome Consortium, Hirst M.

Cell. 2016 Nov 17;167(5):1145-1149. doi: 10.1016/j.cell.2016.11.007. Erratum in: Cell. 2016 Dec 15;167(7):1897.

40.

RNAi screens identify CHD4 as an essential gene in breast cancer growth.

D'Alesio C, Punzi S, Cicalese A, Fornasari L, Furia L, Riva L, Carugo A, Curigliano G, Criscitiello C, Pruneri G, Pelicci PG, Faretta M, Bossi D, Lanfrancone L.

Oncotarget. 2016 Dec 6;7(49):80901-80915. doi: 10.18632/oncotarget.12646.

41.

Maintenance of leukemic cell identity by the activity of the Polycomb complex PRC1 in mice.

Rossi A, Ferrari KJ, Piunti A, Jammula S, Chiacchiera F, Mazzarella L, Scelfo A, Pelicci PG, Pasini D.

Sci Adv. 2016 Oct 7;2(10):e1600972. eCollection 2016 Oct.

42.

In Vivo Functional Platform Targeting Patient-Derived Xenografts Identifies WDR5-Myc Association as a Critical Determinant of Pancreatic Cancer.

Carugo A, Genovese G, Seth S, Nezi L, Rose JL, Bossi D, Cicalese A, Shah PK, Viale A, Pettazzoni PF, Akdemir KC, Bristow CA, Robinson FS, Tepper J, Sanchez N, Gupta S, Estecio MR, Giuliani V, Dellino GI, Riva L, Yao W, Di Francesco ME, Green T, D'Alesio C, Corti D, Kang Y, Jones P, Wang H, Fleming JB, Maitra A, Pelicci PG, Chin L, DePinho RA, Lanfrancone L, Heffernan TP, Draetta GF.

Cell Rep. 2016 Jun 28;16(1):133-147. doi: 10.1016/j.celrep.2016.05.063. Epub 2016 Jun 16.

43.

p46Shc Inhibits Thiolase and Lipid Oxidation in Mitochondria.

Tomilov A, Tomilova N, Shan Y, Hagopian K, Bettaieb A, Kim K, Pelicci PG, Haj F, Ramsey J, Cortopassi G.

J Biol Chem. 2016 Jun 10;291(24):12575-85. doi: 10.1074/jbc.M115.695577. Epub 2016 Apr 8.

44.

PML is required for telomere stability in non-neoplastic human cells.

Marchesini M, Matocci R, Tasselli L, Cambiaghi V, Orleth A, Furia L, Marinelli C, Lombardi S, Sammarelli G, Aversa F, Minucci S, Faretta M, Pelicci PG, Grignani F.

Oncogene. 2016 Apr 7;35(14):1876. doi: 10.1038/onc.2015.312. No abstract available.

PMID:
27052595
45.

Cyclophilin D counteracts P53-mediated growth arrest and promotes Ras tumorigenesis.

Bigi A, Beltrami E, Trinei M, Stendardo M, Pelicci PG, Giorgio M.

Oncogene. 2016 Sep 29;35(39):5132-43. doi: 10.1038/onc.2016.42. Epub 2016 Mar 14.

PMID:
26973251
46.

P66SHC deletion improves fertility and progeric phenotype of late-generation TERC-deficient mice but not their short lifespan.

Giorgio M, Stendardo M, Migliaccio E, Pelicci PG.

Aging Cell. 2016 Jun;15(3):446-54. doi: 10.1111/acel.12448. Epub 2016 Mar 10.

47.

Cell cycle-dependent resolution of DNA double-strand breaks.

Ambrosio S, Di Palo G, Napolitano G, Amente S, Dellino GI, Faretta M, Pelicci PG, Lania L, Majello B.

Oncotarget. 2016 Jan 26;7(4):4949-60. doi: 10.18632/oncotarget.6644.

48.

In vitro and in vivo single-agent efficacy of checkpoint kinase inhibition in acute lymphoblastic leukemia.

Iacobucci I, Di Rorà AG, Falzacappa MV, Agostinelli C, Derenzini E, Ferrari A, Papayannidis C, Lonetti A, Righi S, Imbrogno E, Pomella S, Venturi C, Guadagnuolo V, Cattina F, Ottaviani E, Abbenante MC, Vitale A, Elia L, Russo D, Zinzani PL, Pileri S, Pelicci PG, Martinelli G.

J Hematol Oncol. 2015 Nov 5;8:125. doi: 10.1186/s13045-015-0206-5.

49.

Peak shape clustering reveals biological insights.

Cremona MA, Sangalli LM, Vantini S, Dellino GI, Pelicci PG, Secchi P, Riva L.

BMC Bioinformatics. 2015 Oct 28;16:349. doi: 10.1186/s12859-015-0787-6.

50.

Calcite single crystals as hosts for atomic-scale entrapment and slow release of drugs.

Magnabosco G, Di Giosia M, Polishchuk I, Weber E, Fermani S, Bottoni A, Zerbetto F, Pelicci PG, Pokroy B, Rapino S, Falini G, Calvaresi M.

Adv Healthc Mater. 2015 Sep 16;4(13):1899. doi: 10.1002/adhm.201500631. No abstract available.

PMID:
26379220

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