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Items: 1 to 50 of 124

1.

Unstable chromosome rearrangements in Staphylococcus aureus cause phenotype switching associated with persistent infections.

Guérillot R, Kostoulias X, Donovan L, Li L, Carter GP, Hachani A, Vandelannoote K, Giulieri S, Monk IR, Kunimoto M, Starrs L, Burgio G, Seemann T, Peleg AY, Stinear TP, Howden BP.

Proc Natl Acad Sci U S A. 2019 Sep 16. pii: 201904861. doi: 10.1073/pnas.1904861116. [Epub ahead of print]

2.

Closing the Gap in Surveillance and Audit of Invasive Mold Diseases for Antifungal Stewardship Using Machine Learning.

Baggio D, Peel T, Peleg AY, Avery S, Prayaga M, Foo M, Haffari G, Liu M, Bergmeir C, Ananda-Rajah M.

J Clin Med. 2019 Sep 5;8(9). pii: E1390. doi: 10.3390/jcm8091390.

3.

Synergistic meropenem-tobramycin combination dosage regimens against clinical hypermutable Pseudomonas aeruginosa at simulated epithelial lining fluid concentrations in a dynamic biofilm model.

Bilal H, Bergen PJ, Kim TH, Chung SE, Peleg AY, Oliver A, Nation RL, Landersdorfer CB.

Antimicrob Agents Chemother. 2019 Aug 19. pii: AAC.01293-19. doi: 10.1128/AAC.01293-19. [Epub ahead of print]

PMID:
31427301
4.

The Mechanisms of Disease Caused by Acinetobacter baumannii.

Morris FC, Dexter C, Kostoulias X, Uddin MI, Peleg AY.

Front Microbiol. 2019 Jul 17;10:1601. doi: 10.3389/fmicb.2019.01601. eCollection 2019. Review.

5.

A plasmid-encoded peptide from Staphylococcus aureus induces anti-myeloperoxidase nephritogenic autoimmunity.

Ooi JD, Jiang JH, Eggenhuizen PJ, Chua LL, van Timmeren M, Loh KL, O'Sullivan KM, Gan PY, Zhong Y, Tsyganov K, Shochet LR, Ryan J, Stegeman CA, Fugger L, Reid HH, Rossjohn J, Heeringa P, Holdsworth SR, Peleg AY, Kitching AR.

Nat Commun. 2019 Jul 29;10(1):3392. doi: 10.1038/s41467-019-11255-0.

6.

Carbapenem-Resistant Enterobacteriaceae in Solid Organ Transplantation: Management Principles.

Smibert O, Satlin MJ, Nellore A, Peleg AY.

Curr Infect Dis Rep. 2019 Jun 10;21(7):26. doi: 10.1007/s11908-019-0679-4. Review.

PMID:
31183574
7.

Biofilm formation and migration on ventricular assist device drivelines.

Qu Y, McGiffin D, Kure C, Ozcelik B, Fraser J, Thissen H, Peleg AY.

J Thorac Cardiovasc Surg. 2019 Mar 6. pii: S0022-5223(19)30556-2. doi: 10.1016/j.jtcvs.2019.02.088. [Epub ahead of print]

PMID:
30955967
8.

A population-based analysis of invasive fungal disease in haematology-oncology patients using data linkage of state-wide registries and administrative databases: 2005 - 2016.

Valentine JC, Morrissey CO, Tacey MA, Liew D, Patil S, Peleg AY, Ananda-Rajah MR.

BMC Infect Dis. 2019 Mar 21;19(1):274. doi: 10.1186/s12879-019-3901-y.

9.

Antibiotic resistance and host immune evasion in Staphylococcus aureus mediated by a metabolic adaptation.

Jiang JH, Bhuiyan MS, Shen HH, Cameron DR, Rupasinghe TWT, Wu CM, Le Brun AP, Kostoulias X, Domene C, Fulcher AJ, McConville MJ, Howden BP, Lieschke GJ, Peleg AY.

Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3722-3727. doi: 10.1073/pnas.1812066116. Epub 2019 Feb 11.

10.

Nitrofurantoin and fosfomycin for resistant urinary tract infections: old drugs for emerging problems.

Gardiner BJ, Stewardson AJ, Abbott IJ, Peleg AY.

Aust Prescr. 2019 Feb;42(1):14-19. doi: 10.18773/austprescr.2019.002. Epub 2019 Feb 1. Review. No abstract available.

11.

Fatal disseminated visceral varicella zoster virus infection in a renal transplant recipient.

Loftus MJ, Yong MK, Wilson S, Peleg AY.

Transpl Infect Dis. 2019 Jun;21(3):e13062. doi: 10.1111/tid.13062. Epub 2019 Mar 7.

PMID:
30756453
12.

Characterization of Hypermutator Pseudomonas aeruginosa Isolates from Patients with Cystic Fibrosis in Australia.

Rees VE, Deveson Lucas DS, López-Causapé C, Huang Y, Kotsimbos T, Bulitta JB, Rees MC, Barugahare A, Peleg AY, Nation RL, Oliver A, Boyce JD, Landersdorfer CB.

Antimicrob Agents Chemother. 2019 Mar 27;63(4). pii: e02538-18. doi: 10.1128/AAC.02538-18. Print 2019 Apr.

PMID:
30745381
13.

Identification of Novel Acinetobacter baumannii Host Fatty Acid Stress Adaptation Strategies.

Jiang JH, Hassan KA, Begg SL, Rupasinghe TWT, Naidu V, Pederick VG, Khorvash M, Whittall JJ, Paton JC, Paulsen IT, McDevitt CA, Peleg AY, Eijkelkamp BA.

MBio. 2019 Feb 5;10(1). pii: e02056-18. doi: 10.1128/mBio.02056-18.

14.

Evolution of Daptomycin Resistance in Coagulase-Negative Staphylococci Involves Mutations of the Essential Two-Component Regulator WalKR.

Jiang JH, Dexter C, Cameron DR, Monk IR, Baines SL, Abbott IJ, Spelman DW, Kostoulias X, Nethercott C, Howden BP, Peleg AY.

Antimicrob Agents Chemother. 2019 Feb 26;63(3). pii: e01926-18. doi: 10.1128/AAC.01926-18. Print 2019 Mar.

15.

OXA-23 Is a Prevalent Mechanism Contributing to Sulbactam Resistance in Diverse Acinetobacter baumannii Clinical Strains.

Yang Y, Xu Q, Li T, Fu Y, Shi Y, Lan P, Zhao D, Chen Q, Zhou Z, Jiang Y, Peleg AY, Yu Y.

Antimicrob Agents Chemother. 2018 Dec 21;63(1). pii: e01676-18. doi: 10.1128/AAC.01676-18. Print 2019 Jan. No abstract available.

16.

A Randomized Study of Quantiferon CMV-directed Versus Fixed-duration Valganciclovir Prophylaxis to Reduce Late CMV After Lung Transplantation.

Westall GP, Cristiano Y, Levvey BJ, Whitford H, Paraskeva MA, Paul E, Peleg AY, Snell GI.

Transplantation. 2019 May;103(5):1005-1013. doi: 10.1097/TP.0000000000002454.

PMID:
30247316
17.

Effect of Piperacillin-Tazobactam vs Meropenem on 30-Day Mortality for Patients With E coli or Klebsiella pneumoniae Bloodstream Infection and Ceftriaxone Resistance: A Randomized Clinical Trial.

Harris PNA, Tambyah PA, Lye DC, Mo Y, Lee TH, Yilmaz M, Alenazi TH, Arabi Y, Falcone M, Bassetti M, Righi E, Rogers BA, Kanj S, Bhally H, Iredell J, Mendelson M, Boyles TH, Looke D, Miyakis S, Walls G, Al Khamis M, Zikri A, Crowe A, Ingram P, Daneman N, Griffin P, Athan E, Lorenc P, Baker P, Roberts L, Beatson SA, Peleg AY, Harris-Brown T, Paterson DL; MERINO Trial Investigators and the Australasian Society for Infectious Disease Clinical Research Network (ASID-CRN).

JAMA. 2018 Sep 11;320(10):984-994. doi: 10.1001/jama.2018.12163. Erratum in: JAMA. 2019 Jun 18;321(23):2370.

18.

Comprehensive antibiotic-linked mutation assessment by resistance mutation sequencing (RM-seq).

Guérillot R, Li L, Baines S, Howden B, Schultz MB, Seemann T, Monk I, Pidot SJ, Gao W, Giulieri S, Gonçalves da Silva A, D'Agata A, Tomita T, Peleg AY, Stinear TP, Howden BP.

Genome Med. 2018 Aug 31;10(1):63. doi: 10.1186/s13073-018-0572-z.

19.

Meropenem Combined with Ciprofloxacin Combats Hypermutable Pseudomonas aeruginosa from Respiratory Infections of Cystic Fibrosis Patients.

Rees VE, Yadav R, Rogers KE, Bulitta JB, Wirth V, Oliver A, Boyce JD, Peleg AY, Nation RL, Landersdorfer CB.

Antimicrob Agents Chemother. 2018 Oct 24;62(11). pii: e01150-18. doi: 10.1128/AAC.01150-18. Print 2018 Nov.

20.

Spectrum of illness among returned Australian travellers from Bali, Indonesia: a 5-year retrospective observational study.

Sohail A, McGuinness SL, Lightowler R, Leder K, Jomon B, Bain CA, Peleg AY.

Intern Med J. 2019 Jan;49(1):34-40. doi: 10.1111/imj.13993.

PMID:
29869360
21.

In vivo atomic force microscopy-infrared spectroscopy of bacteria.

Kochan K, Perez-Guaita D, Pissang J, Jiang JH, Peleg AY, McNaughton D, Heraud P, Wood BR.

J R Soc Interface. 2018 Mar;15(140). pii: 20180115. doi: 10.1098/rsif.2018.0115.

22.

Evolution of carbapenem resistance in Acinetobacter baumannii during a prolonged infection.

Hawkey J, Ascher DB, Judd LM, Wick RR, Kostoulias X, Cleland H, Spelman DW, Padiglione A, Peleg AY, Holt KE.

Microb Genom. 2018 Mar;4(3). doi: 10.1099/mgen.0.000165. Epub 2018 Mar 16.

23.

Elucidation of the pharmacokinetic/pharmacodynamic determinants of fosfomycin activity against Pseudomonas aeruginosa using a dynamic in vitro model.

Bilal H, Peleg AY, McIntosh MP, Styles IK, Hirsch EB, Landersdorfer CB, Bergen PJ.

J Antimicrob Chemother. 2018 Jun 1;73(6):1570-1578. doi: 10.1093/jac/dky045.

PMID:
29506207
24.

Mobile phones and computer keyboards: unlikely reservoirs of multidrug-resistant organisms in the tertiary intensive care unit.

Smibert OC, Aung AK, Woolnough E, Carter GP, Schultz MB, Howden BP, Seemann T, Spelman D, McGloughlin S, Peleg AY.

J Hosp Infect. 2018 Jul;99(3):295-298. doi: 10.1016/j.jhin.2018.02.013. Epub 2018 Mar 2.

PMID:
29501730
25.

Optimization of a Meropenem-Tobramycin Combination Dosage Regimen against Hypermutable and Nonhypermutable Pseudomonas aeruginosa via Mechanism-Based Modeling and the Hollow-Fiber Infection Model.

Landersdorfer CB, Rees VE, Yadav R, Rogers KE, Kim TH, Bergen PJ, Cheah SE, Boyce JD, Peleg AY, Oliver A, Shin BS, Nation RL, Bulitta JB.

Antimicrob Agents Chemother. 2018 Mar 27;62(4). pii: e02055-17. doi: 10.1128/AAC.02055-17. Print 2018 Apr.

26.

Convergent Evolution Driven by Rifampin Exacerbates the Global Burden of Drug-Resistant Staphylococcus aureus.

Guérillot R, Gonçalves da Silva A, Monk I, Giulieri S, Tomita T, Alison E, Porter J, Pidot S, Gao W, Peleg AY, Seemann T, Stinear TP, Howden BP.

mSphere. 2018 Jan 24;3(1). pii: e00550-17. doi: 10.1128/mSphere.00550-17. eCollection 2018 Jan-Feb.

27.

Fosfomycin efficacy and emergence of resistance among Enterobacteriaceae in an in vitro dynamic bladder infection model.

Abbott IJ, Meletiadis J, Belghanch I, Wijma RA, Kanioura L, Roberts JA, Peleg AY, Mouton JW.

J Antimicrob Chemother. 2018 Mar 1;73(3):709-719. doi: 10.1093/jac/dkx441.

PMID:
29253153
28.

Donor-Derived Mycoplasma hominis and an Apparent Cluster of M. hominis Cases in Solid Organ Transplant Recipients.

Smibert OC, Wilson HL, Sohail A, Narayanasamy S, Schultz MB, Ballard SA, Kwong JC, de Boer J, Morrissey CO, Peleg AY, Snell GI, Paraskeva MA, Jenney AWJ.

Clin Infect Dis. 2017 Oct 16;65(9):1504-1508. doi: 10.1093/cid/cix601.

PMID:
29048510
29.

Antibiotic exposure and interpersonal variance mask the effect of ivacaftor on respiratory microbiota composition.

Peleg AY, Choo JM, Langan KM, Edgeworth D, Keating D, Wilson J, Rogers GB, Kotsimbos T.

J Cyst Fibros. 2018 Jan;17(1):50-56. doi: 10.1016/j.jcf.2017.08.002. Epub 2017 Oct 15.

PMID:
29042177
30.

Synthesis of novel 1,2,5-oxadiazoles and evaluation of action against Acinetobacter baumannii.

Christoff RM, Murray GL, Kostoulias XP, Peleg AY, Abbott BM.

Bioorg Med Chem. 2017 Dec 15;25(24):6267-6272. doi: 10.1016/j.bmc.2017.08.015. Epub 2017 Aug 10.

PMID:
29032931
31.

Structural Basis for Linezolid Binding Site Rearrangement in the Staphylococcus aureus Ribosome.

Belousoff MJ, Eyal Z, Radjainia M, Ahmed T, Bamert RS, Matzov D, Bashan A, Zimmerman E, Mishra S, Cameron D, Elmlund H, Peleg AY, Bhushan S, Lithgow T, Yonath A.

MBio. 2017 May 9;8(3). pii: e00395-17. doi: 10.1128/mBio.00395-17.

32.

Vancomycin-intermediate Staphylococcus aureus isolates are attenuated for virulence when compared with susceptible progenitors.

Cameron DR, Lin YH, Trouillet-Assant S, Tafani V, Kostoulias X, Mouhtouris E, Skinner N, Visvanathan K, Baines SL, Howden B, Monk IR, Laurent F, Stinear TP, Howden BP, Peleg AY.

Clin Microbiol Infect. 2017 Oct;23(10):767-773. doi: 10.1016/j.cmi.2017.03.027. Epub 2017 Apr 7.

33.

Global Gene Expression Profile of Acinetobacter baumannii During Bacteremia.

Murray GL, Tsyganov K, Kostoulias XP, Bulach DM, Powell D, Creek DJ, Boyce JD, Paulsen IT, Peleg AY.

J Infect Dis. 2017 Feb 15;215(suppl_1):S52-S57. doi: 10.1093/infdis/jiw529.

PMID:
28375520
34.

Proposed primary endpoints for use in clinical trials that compare treatment options for bloodstream infection in adults: a consensus definition.

Harris PNA, McNamara JF, Lye DC, Davis JS, Bernard L, Cheng AC, Doi Y, Fowler VG Jr, Kaye KS, Leibovici L, Lipman J, Llewelyn MJ, Munoz-Price S, Paul M, Peleg AY, Rodríguez-Baño J, Rogers BA, Seifert H, Thamlikitkul V, Thwaites G, Tong SYC, Turnidge J, Utili R, Webb SAR, Paterson DL.

Clin Microbiol Infect. 2017 Aug;23(8):533-541. doi: 10.1016/j.cmi.2016.10.023. Epub 2016 Nov 1. Review.

35.

Polymicrobial infections involving clinically relevant Gram-negative bacteria and fungi.

Dhamgaye S, Qu Y, Peleg AY.

Cell Microbiol. 2016 Dec;18(12):1716-1722. doi: 10.1111/cmi.12674. Epub 2016 Oct 20. Review.

PMID:
27665610
36.

Optimizing Microplate Biofilm Assays to Screen Anti-infective Surfaces.

Qu Y, Thissen H, McGiffin D, Peleg AY.

Trends Biotechnol. 2017 Jan;35(1):3-5. doi: 10.1016/j.tibtech.2016.09.001. Epub 2016 Sep 23. No abstract available.

PMID:
27666729
37.
38.

Safety, clinical effectiveness and trough plasma concentrations of intravenous posaconazole in patients with haematological malignancies and/or undergoing allogeneic haematopoietic stem cell transplantation: off-trial experience.

Jeong W, Haywood P, Shanmuganathan N, Lindsay J, Urbancic K, Ananda-Rajah MR, Chen SC, Bajel A, Ritchie D, Grigg A, Seymour JF, Peleg AY, Kong DC, Slavin MA.

J Antimicrob Chemother. 2016 Dec;71(12):3540-3547. Epub 2016 Aug 11.

PMID:
27521358
39.

Acinetobacter baumannii phenylacetic acid metabolism influences infection outcome through a direct effect on neutrophil chemotaxis.

Bhuiyan MS, Ellett F, Murray GL, Kostoulias X, Cerqueira GM, Schulze KE, Mahamad Maifiah MH, Li J, Creek DJ, Lieschke GJ, Peleg AY.

Proc Natl Acad Sci U S A. 2016 Aug 23;113(34):9599-604. doi: 10.1073/pnas.1523116113. Epub 2016 Aug 9.

40.

A Comparative Analysis Between Antibiotic- and Nonantibiotic-Associated Delayed Cutaneous Adverse Drug Reactions.

Trubiano JA, Aung AK, Nguyen M, Fehily SR, Graudins L, Cleland H, Padiglione A, Peleg AY.

J Allergy Clin Immunol Pract. 2016 Nov - Dec;4(6):1187-1193. doi: 10.1016/j.jaip.2016.04.026. Epub 2016 Jun 7.

PMID:
27283055
41.

Anti-infective Surface Coatings: Design and Therapeutic Promise against Device-Associated Infections.

Coad BR, Griesser HJ, Peleg AY, Traven A.

PLoS Pathog. 2016 Jun 2;12(6):e1005598. doi: 10.1371/journal.ppat.1005598. eCollection 2016 Jun. No abstract available.

42.

Clinically relevant concentrations of fosfomycin combined with polymyxin B, tobramycin or ciprofloxacin enhance bacterial killing of Pseudomonas aeruginosa, but do not suppress the emergence of fosfomycin resistance.

Walsh CC, Landersdorfer CB, McIntosh MP, Peleg AY, Hirsch EB, Kirkpatrick CM, Bergen PJ.

J Antimicrob Chemother. 2016 Aug;71(8):2218-29. doi: 10.1093/jac/dkw115. Epub 2016 Apr 26.

PMID:
27118778
43.

Antibiotic regimen based on population analysis of residing persister cells eradicates Staphylococcus epidermidis biofilms.

Yang S, Hay ID, Cameron DR, Speir M, Cui B, Su F, Peleg AY, Lithgow T, Deighton MA, Qu Y.

Sci Rep. 2015 Dec 21;5:18578. doi: 10.1038/srep18578.

44.

Daptomycin-Nonsusceptible Staphylococcus aureus: The Role of Combination Therapy with Daptomycin and Gentamicin.

Jiang JH, Peleg AY.

Genes (Basel). 2015 Nov 30;6(4):1256-67. doi: 10.3390/genes6041256.

45.

Managing Pseudomonas aeruginosa respiratory infections in cystic fibrosis.

Langan KM, Kotsimbos T, Peleg AY.

Curr Opin Infect Dis. 2015 Dec;28(6):547-56. doi: 10.1097/QCO.0000000000000217. Review. Erratum in: Curr Opin Infect Dis. 2016 Feb;29(1):98.

PMID:
26524327
46.

Impact of a Cross-Kingdom Signaling Molecule of Candida albicans on Acinetobacter baumannii Physiology.

Kostoulias X, Murray GL, Cerqueira GM, Kong JB, Bantun F, Mylonakis E, Khoo CA, Peleg AY.

Antimicrob Agents Chemother. 2015 Oct 19;60(1):161-7. doi: 10.1128/AAC.01540-15. Print 2016 Jan.

47.

Insights on virulence from the complete genome of Staphylococcus capitis.

Cameron DR, Jiang JH, Hassan KA, Elbourne LD, Tuck KL, Paulsen IT, Peleg AY.

Front Microbiol. 2015 Sep 23;6:980. doi: 10.3389/fmicb.2015.00980. eCollection 2015.

48.

Species identification within Acinetobacter calcoaceticus-baumannii complex using MALDI-TOF MS.

Toh BE, Paterson DL, Kamolvit W, Zowawi H, Kvaskoff D, Sidjabat H, Wailan A, Peleg AY, Huber CA.

J Microbiol Methods. 2015 Nov;118:128-32. doi: 10.1016/j.mimet.2015.09.006. Epub 2015 Sep 14.

PMID:
26381662
49.

The influence of bacterial interaction on the virulence of Cryptococcus neoformans.

Dhamgaye S, Murray GL, Peleg AY.

Virulence. 2015;6(7):677-8. doi: 10.1080/21505594.2015.1088632.

50.

Distribution of β-lactamase genes among carbapenem-resistant Klebsiella pneumoniae strains isolated from patients in Turkey.

Iraz M, Özad Düzgün A, Sandallı C, Doymaz MZ, Akkoyunlu Y, Saral A, Peleg AY, Özgümüş OB, Beriş FŞ, Karaoğlu H, Çopur Çiçek A.

Ann Lab Med. 2015 Nov;35(6):595-601. doi: 10.3343/alm.2015.35.6.595.

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