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Co-occurring alterations in the RAS-MAPK pathway limit response to MET inhibitor treatment in MET exon 14 skipping mutation-positive lung cancer.

Rotow JK, Gui P, Wu W, Raymond VM, Lanman RB, Kaye FJ, Peled N, Fece de la Cruz F, Nadres B, Corcoran RB, Yeh I, Bastian BC, Starostik P, Newsom K, Olivas V, Wolff AM, Fraser JS, Collisson EA, McCoach CE, Camidge DR, Pacheco J, Bazhenova L, Li T, Bivona TG, Blakely CM.

Clin Cancer Res. 2019 Sep 23. pii: clincanres.1667.2019. doi: 10.1158/1078-0432.CCR-19-1667. [Epub ahead of print]


Caudate stimulation enhances learning.

Bick SK, Patel SR, Katnani HA, Peled N, Widge A, Cash SS, Eskandar EN.

Brain. 2019 Oct 1;142(10):2930-2937. doi: 10.1093/brain/awz254.


Position of an international panel of lung cancer experts on the decision for expansion of approval for pembrolizumab in advanced non-small cell lung cancer with a PD-L1 expression level of ≥ 1% by the U.S. Food and Drug Administration.

Mountzios G, Remon J, Novello S, Blais N, Califano R, Cufer T, Dingemans AM, Liu SV, Peled N, Pennell NA, Reck M, Rolfo C, Tan D, Vansteenkiste J, West H, Besse B.

Ann Oncol. 2019 Sep 3. pii: mdz295. doi: 10.1093/annonc/mdz295. [Epub ahead of print] No abstract available.


Immune-related Neutropenia Following Treatment With Immune Checkpoint Inhibitors.

Finkel I, Sternschuss M, Wollner M, Shamai S, Peled N, Turgeman I, Shochat T, Dudnik E; Israel Lung Cancer Group.

J Immunother. 2019 Sep 6. doi: 10.1097/CJI.0000000000000293. [Epub ahead of print]


Decoding task engagement from distributed network electrophysiology in humans.

Provenza NR, Paulk AC, Peled N, Restrepo MI, Cash SS, Dougherty DD, Eskandar EN, Borton DA, Widge AS.

J Neural Eng. 2019 Aug 16;16(5):056015. doi: 10.1088/1741-2552/ab2c58.


Definition of synchronous oligo-metastatic non-small cell lung cancer - a consensus report.

Dingemans AC, Hendriks LEL, Berghmans T, Levy A, Hasan B, Faivre-Finn C, Giaj-Levra M, Giaj-Levra N, Girard N, Greillier L, Lantuéjoul S, Edwards J, O'Brien M, Reck M, Smit EF, Van Schil P, Postmus PE, Ramella S, Lievens Y, Gaga M, Peled N, Scagliotti GV, Senan S, Paz-Ares L, Guckenberger M, McDonald F, Ekman S, Cufer T, Gietema H, Infante M, Dziadziuszko R, Peters S, Porta RR, Vansteenkiste J, Dooms C, de Ruysscher D, Besse B, Novello S.

J Thorac Oncol. 2019 Aug 6. pii: S1556-0864(19)30655-0. doi: 10.1016/j.jtho.2019.07.025. [Epub ahead of print]


Validation of Microsatellite Instability Detection Using a Comprehensive Plasma-Based Genotyping Panel.

Willis J, Lefterova MI, Artyomenko A, Kasi PM, Nakamura Y, Mody K, Catenacci DVT, Fakih M, Barbacioru C, Zhao J, Sikora M, Fairclough SR, Lee H, Kim KM, Kim ST, Kim J, Gavino D, Benavides M, Peled N, Nguyen T, Cusnir M, Eskander RN, Azzi G, Yoshino T, Banks KC, Raymond VM, Lanman RB, Chudova DI, Talasaz A, Kopetz S, Lee J, Odegaard JI.

Clin Cancer Res. 2019 Aug 4. doi: 10.1158/1078-0432.CCR-19-1324. [Epub ahead of print]


IFN-β is a macrophage-derived effector cytokine facilitating the resolution of bacterial inflammation.

Kumaran Satyanarayanan S, El Kebir D, Soboh S, Butenko S, Sekheri M, Saadi J, Peled N, Assi S, Othman A, Schif-Zuck S, Feuermann Y, Barkan D, Sher N, Filep JG, Ariel A.

Nat Commun. 2019 Aug 2;10(1):3471. doi: 10.1038/s41467-019-10903-9.


Is ALK Inhibitor a Contraindication for Subsequent IVF Pregnancy?

Gillis R, Meirovitz M, Ben David Hadani M, Hourvitz A, Peled N.

J Thorac Oncol. 2019 Aug;14(8):e176-e178. doi: 10.1016/j.jtho.2019.03.016. No abstract available.


Retroperitoneal Pseudotumor Induced by Crizotinib Treatment for c-MET exon 14 Skip Mutation NCSLC.

Tiganas A, Gillis R, Refaely Y, Nado A, Peled N.

J Thorac Oncol. 2019 Aug;14(8):e172-e174. doi: 10.1016/j.jtho.2019.03.018. No abstract available.


Decoding Hidden Cognitive States From Behavior and Physiology Using a Bayesian Approach.

Yousefi A, Basu I, Paulk AC, Peled N, Eskandar EN, Dougherty DD, Cash SS, Widge AS, Eden UT.

Neural Comput. 2019 Sep;31(9):1751-1788. doi: 10.1162/neco_a_01196. Epub 2019 Jul 23.


Increased Incidence of Lung Cancer Among Patients With Superficial Transitional Cell Carcinoma: A Potential Risk Cohort for Lung Cancer Screening.

Tolwin Y, Gillis R, Agmon IN, Shrem NS, Rosenbaum E, Peled N.

Clin Lung Cancer. 2019 Jun 18. pii: S1525-7304(19)30152-4. doi: 10.1016/j.cllc.2019.06.010. [Epub ahead of print]


Is Lumbosacral Transitional Vertebra Associated with Degenerative Lumbar Spinal Stenosis?

Abbas J, Peled N, Hershkovitz I, Hamoud K.

Biomed Res Int. 2019 Jun 10;2019:3871819. doi: 10.1155/2019/3871819. eCollection 2019.


Prevention and Early Detection for NSCLC: Advances in Thoracic Oncology 2018.

Balata H, Fong KM, Hendriks LE, Lam S, Ostroff JS, Peled N, Wu N, Aggarwal C.

J Thorac Oncol. 2019 Sep;14(9):1513-1527. doi: 10.1016/j.jtho.2019.06.011. Epub 2019 Jun 19. Review.


Hospital-onset adult invasive pneumococcal disease in Israel: Sicker patients, different pathogens.

Kenig A, Regev-Yochay G, Khakshoor S, Cohen-Poradosu R, Bishara J, Glikman D, Hershman-Sarafov M, Dagan R, Zimhony O; IAIPD Research Group.

Int J Infect Dis. 2019 Aug;85:195-202. doi: 10.1016/j.ijid.2019.06.013. Epub 2019 Jun 18.


Immune checkpoint inhibitors for patients with advanced lung cancer and oncogenic driver alterations: results from the IMMUNOTARGET registry.

Mazières J, Drilon A, Lusque A, Mhanna L, Cortot AB, Mezquita L, Thai AA, Mascaux C, Couraud S, Veillon R, Van Den Heuvel M, Neal J, Peled N, Früh M, Ng TL, Gounant V, Popat S, Diebold J, Sabari J, Zhu VW, Rothschild SI, Bironzo P, Martinez A, Curioni-Fontecedro A, Rosell R, Lattuca-Truc M, Wiesweg M, Besse B, Solomon B, Barlesi F, Schouten RD, Wakelee H, Camidge DR, Zalcman G, Novello S, Ou SI, Milia J, Gautschi O.

Ann Oncol. 2019 May 24. pii: mdz167. doi: 10.1093/annonc/mdz167. [Epub ahead of print]


Lung Cancer in Young Patients: Higher Rate of Driver Mutations and Brain Involvement, but Better Survival.

Suidan AM, Roisman L, Belilovski Rozenblum A, Ilouze M, Dudnik E, Zer A, Peled N.

J Glob Oncol. 2019 May;5:1-8. doi: 10.1200/JGO.18.00216. No abstract available.


Efficacy and Safety of BRAF Inhibitors With or Without MEK Inhibitors in BRAF-Mutant Advanced Non-Small-Cell Lung Cancer: Findings From a Real-Life Cohort.

Dudnik E, Bar J, Peled N, Bshara E, Kuznetsov T, Cohen AY, Shochat T, Nechushtan H, Onn A, Agbarya A, Moskovitz M, Keren S, Popovits-Hadar N, Urban D, Mishaeli M, Rabinovich NM, Brenner R, Zer A, Rotem O, Roisman LC, Wollner M; Israel Lung Cancer Group.

Clin Lung Cancer. 2019 Jul;20(4):278-286.e1. doi: 10.1016/j.cllc.2019.03.007. Epub 2019 Apr 5.


Efficacy and Safety of ALK Tyrosine Kinase Inhibitors in Elderly Patients with Advanced ALK-Positive Non-Small Cell Lung Cancer: Findings from the Real-Life Cohort.

Bedas A, Peled N, Maimon Rabinovich N, Mishaeli M, Shochat T, Zer A, Rotem O, Allen AM, Bar J, Dudnik E; On behalf of the Israel Lung Cancer Group.

Oncol Res Treat. 2019;42(5):275-282. doi: 10.1159/000499086. Epub 2019 Apr 5.


Consistent linear and non-linear responses to invasive electrical brain stimulation across individuals and primate species with implanted electrodes.

Basu I, Robertson MM, Crocker B, Peled N, Farnes K, Vallejo-Lopez DI, Deng H, Thombs M, Martinez-Rubio C, Cheng JJ, McDonald E, Dougherty DD, Eskandar EN, Widge AS, Paulk AC, Cash SS.

Brain Stimul. 2019 Jul - Aug;12(4):877-892. doi: 10.1016/j.brs.2019.03.007. Epub 2019 Mar 11.


Nivolumab Induced Lethal Aplastic Anemia in a Patient with Metastatic Melanoma.

Rouvinov K, Nalbandyan K, Kozlov V, Peled N, Yakobson A.

Case Rep Oncol. 2019 Jan 4;12(1):29-32. doi: 10.1159/000495980. eCollection 2019 Jan-Apr.


Correction to: Trimodally treatment for stage IIIa NSCLC patients increases survival while not effecting surgical mortality or complexity.

Aravot D, Barac YD, Krutzwald-Josefson E, Allen AM, Flex D, Peled N, Kramer MR, Peysakhovich Y, Saute M.

J Cardiothorac Surg. 2019 Feb 12;14(1):37. doi: 10.1186/s13019-019-0856-4.


Two are better than one on progression through MET mechanism for EGFR+ NSCLC patients.

Kian W, Roisman LC, Peled N.

Transl Lung Cancer Res. 2018 Dec;7(Suppl 4):S334-S335. doi: 10.21037/tlcr.2018.12.01. No abstract available.


Trimodally treatment for stage IIIa NSCLC patients increases survival while not effecting surgical mortality or complexity.

Aravot D, Barac YD, Krutzwald-Josefson E, Allen AM, Flex D, Peled N, Kramer MR, Peysakhovich Y, Saute M.

J Cardiothorac Surg. 2019 Jan 9;14(1):7. doi: 10.1186/s13019-018-0829-z. Erratum in: J Cardiothorac Surg. 2019 Feb 12;14(1):37.


Updated Analysis of KEYNOTE-024: Pembrolizumab Versus Platinum-Based Chemotherapy for Advanced Non-Small-Cell Lung Cancer With PD-L1 Tumor Proportion Score of 50% or Greater.

Reck M, Rodríguez-Abreu D, Robinson AG, Hui R, Csőszi T, Fülöp A, Gottfried M, Peled N, Tafreshi A, Cuffe S, O'Brien M, Rao S, Hotta K, Vandormael K, Riccio A, Yang J, Pietanza MC, Brahmer JR.

J Clin Oncol. 2019 Mar 1;37(7):537-546. doi: 10.1200/JCO.18.00149. Epub 2019 Jan 8.


Cortical Signal Suppression (CSS) for Detection of Subcortical Activity Using MEG and EEG.

Samuelsson JG, Khan S, Sundaram P, Peled N, Hämäläinen MS.

Brain Topogr. 2019 Mar;32(2):215-228. doi: 10.1007/s10548-018-00694-5. Epub 2019 Jan 3.


Lumbar Schmorl's Nodes and Their Correlation with Spine Configuration and Degeneration.

Abbas J, Hamoud K, Peled N, Hershkovitz I.

Biomed Res Int. 2018 Nov 7;2018:1574020. doi: 10.1155/2018/1574020. eCollection 2018.


Biomarkers in Lung Cancer Screening: Achievements, Promises, and Challenges.

Seijo LM, Peled N, Ajona D, Boeri M, Field JK, Sozzi G, Pio R, Zulueta JJ, Spira A, Massion PP, Mazzone PJ, Montuenga LM.

J Thorac Oncol. 2019 Mar;14(3):343-357. doi: 10.1016/j.jtho.2018.11.023. Epub 2018 Dec 4. Review.


Increased Risk for Cancer in Young Patients with Severe Obstructive Sleep Apnea.

Brenner R, Kivity S, Peker M, Reinhorn D, Keinan-Boker L, Silverman B, Liphsitz I, Kolitz T, Levy C, Shlomi D, Pillar G, Peled N.

Respiration. 2019;97(1):15-23. doi: 10.1159/000486577. Epub 2018 Nov 12.


Targeted Tissue and Cell-Free Tumor DNA Sequencing of Advanced Lung Squamous-Cell Carcinoma Reveals Clinically Significant Prevalence of Actionable Alterations.

Lam VK, Tran HT, Banks KC, Lanman RB, Rinsurongkawong W, Peled N, Lewis J, Lee JJ, Roth J, Roarty EB, Swisher S, Talasaz A, Futreal PA, Papadimitrakopoulou V, Heymach JV, Zhang J.

Clin Lung Cancer. 2019 Jan;20(1):30-36.e3. doi: 10.1016/j.cllc.2018.08.020. Epub 2018 Sep 5.


Rare targetable drivers (RTDs) in non-small cell lung cancer (NSCLC): Outcomes with immune check-point inhibitors (ICPi).

Dudnik E, Bshara E, Grubstein A, Fridel L, Shochat T, Roisman LC, Ilouze M, Rozenblum AB, Geva S, Zer A, Rotem O, Allen AM, Peled N.

Lung Cancer. 2018 Oct;124:117-124. doi: 10.1016/j.lungcan.2018.07.044. Epub 2018 Aug 3.


ALK IHC and FISH discordant results in patients with NSCLC and treatment response: for discussion of the question-to treat or not to treat?

Cabillic F, Hofman P, Ilie M, Peled N, Hochmair M, Dietel M, Von Laffert M, Gosney JR, Lopez-Rios F, Erb G, Schalles U, Barlesi F.

ESMO Open. 2018 Sep 17;3(6):e000419. doi: 10.1136/esmoopen-2018-000419. eCollection 2018.


Intensity-modulated radiotherapy is a safe and effective treatment for localized malignant pleural mesothelioma.

Simon M, Shochat T, Peled N, Zer A, Kramer MR, Eldan O, Saute M, Dudnik ER, Allen AM.

Thorac Cancer. 2018 Nov;9(11):1470-1475. doi: 10.1111/1759-7714.12860. Epub 2018 Sep 21.


New drugs in thoracic oncology: needs and knowledge - an online ERS Lung Cancer Assembly survey.

Berghmans T, Evison M, Blum TG, Peled N, Cadranel J.

ERJ Open Res. 2018 Sep 3;4(3). pii: 00040-2018. doi: 10.1183/23120541.00040-2018. eCollection 2018 Jul.


The Clinical Impact of Comprehensive Genomic Testing of Circulating Cell-Free DNA in Advanced Lung Cancer.

Laufer-Geva S, Rozenblum AB, Twito T, Grinberg R, Dvir A, Soussan-Gutman L, Ilouze M, Roisman LC, Dudnik E, Zer A, Rotem O, Lanman RB, Peled N.

J Thorac Oncol. 2018 Nov;13(11):1705-1716. doi: 10.1016/j.jtho.2018.07.101. Epub 2018 Aug 16.


Frequency of Brain Metastases and Multikinase Inhibitor Outcomes in Patients With RET-Rearranged Lung Cancers.

Drilon A, Lin JJ, Filleron T, Ni A, Milia J, Bergagnini I, Hatzoglou V, Velcheti V, Offin M, Li B, Carbone DP, Besse B, Mok T, Awad MM, Wolf J, Owen D, Camidge DR, Riely GJ, Peled N, Kris MG, Mazieres J, Gainor JF, Gautschi O.

J Thorac Oncol. 2018 Oct;13(10):1595-1601. doi: 10.1016/j.jtho.2018.07.004. Epub 2018 Jul 11.


Non-invasive early detection of malignant pulmonary nodules by FISH-based sputum test.

Shlomi D, Peled N, Schwarz YA, Soo Hoo GW, Batra RK, Fink G, Kaplan T, Cohen L, Mollan S, Burfeind WR Jr.

Cancer Genet. 2018 Oct;226-227:1-10. doi: 10.1016/j.cancergen.2018.04.118. Epub 2018 May 10.


Diverse EGFR Exon 20 Insertions and Co-Occurring Molecular Alterations Identified by Comprehensive Genomic Profiling of NSCLC.

Riess JW, Gandara DR, Frampton GM, Madison R, Peled N, Bufill JA, Dy GK, Ou SI, Stephens PJ, McPherson JD, Lara PN Jr, Burich RA, Ross JS, Miller VA, Ali SM, Mack PC, Schrock AB.

J Thorac Oncol. 2018 Oct;13(10):1560-1568. doi: 10.1016/j.jtho.2018.06.019. Epub 2018 Jul 5.


Pneumococcal Meningitis in Adults after Introduction of PCV7 and PCV13, Israel, July 2009-June 20151.

Regev-Yochay G, Reisenberg K, Katzir M, Wiener-Well Y, Rahav G, Strahilevitz J, Istomin V, Tsyba E, Peretz A, Khakshoor S, Dagan R; Israeli Adult Invasive Pneumococcal Disease Group.

Emerg Infect Dis. 2018 Jul;24(7):1275-1284. doi: 10.3201/eid2407.170721.


Liquid Biopsy for Advanced Non-Small Cell Lung Cancer (NSCLC): A Statement Paper from the IASLC.

Rolfo C, Mack PC, Scagliotti GV, Baas P, Barlesi F, Bivona TG, Herbst RS, Mok TS, Peled N, Pirker R, Raez LE, Reck M, Riess JW, Sequist LV, Shepherd FA, Sholl LM, Tan DSW, Wakelee HA, Wistuba II, Wynes MW, Carbone DP, Hirsch FR, Gandara DR.

J Thorac Oncol. 2018 Sep;13(9):1248-1268. doi: 10.1016/j.jtho.2018.05.030. Epub 2018 Jun 6. Review.


Assembly 11: thoracic oncology.

Bostantzoglou C, Peled N.

Breathe (Sheff). 2018 Jun;14(2):163-164. doi: 10.1183/20734735.016918.


STK11/LKB1 Mutations and PD-1 Inhibitor Resistance in KRAS-Mutant Lung Adenocarcinoma.

Skoulidis F, Goldberg ME, Greenawalt DM, Hellmann MD, Awad MM, Gainor JF, Schrock AB, Hartmaier RJ, Trabucco SE, Gay L, Ali SM, Elvin JA, Singal G, Ross JS, Fabrizio D, Szabo PM, Chang H, Sasson A, Srinivasan S, Kirov S, Szustakowski J, Vitazka P, Edwards R, Bufill JA, Sharma N, Ou SI, Peled N, Spigel DR, Rizvi H, Aguilar EJ, Carter BW, Erasmus J, Halpenny DF, Plodkowski AJ, Long NM, Nishino M, Denning WL, Galan-Cobo A, Hamdi H, Hirz T, Tong P, Wang J, Rodriguez-Canales J, Villalobos PA, Parra ER, Kalhor N, Sholl LM, Sauter JL, Jungbluth AA, Mino-Kenudson M, Azimi R, Elamin YY, Zhang J, Leonardi GC, Jiang F, Wong KK, Lee JJ, Papadimitrakopoulou VA, Wistuba II, Miller VA, Frampton GM, Wolchok JD, Shaw AT, Jänne PA, Stephens PJ, Rudin CM, Geese WJ, Albacker LA, Heymach JV.

Cancer Discov. 2018 Jul;8(7):822-835. doi: 10.1158/2159-8290.CD-18-0099. Epub 2018 May 17.


BRAF Mutant Lung Cancer: Programmed Death Ligand 1 Expression, Tumor Mutational Burden, Microsatellite Instability Status, and Response to Immune Check-Point Inhibitors.

Dudnik E, Peled N, Nechushtan H, Wollner M, Onn A, Agbarya A, Moskovitz M, Keren S, Popovits-Hadari N, Urban D, Mishaeli M, Zer A, Allen AM, Rabinovich NM, Rotem O, Kuznetsov T, Shochat T, Roisman LC, Bar J; Israel Lung Cancer Group.

J Thorac Oncol. 2018 Aug;13(8):1128-1137. doi: 10.1016/j.jtho.2018.04.024. Epub 2018 Apr 30.


Stereotactic body radiotherapy for central lung tumors, yes we can!

Korzets Ceder Y, Fenig E, Popvtzer A, Peled N, Kramer MR, Saute M, Bragilovsky D, Schochat T, Allen AM.

Radiat Oncol. 2018 Apr 25;13(1):77. doi: 10.1186/s13014-018-1017-y.


High-Dose Radiotherapy as Neoadjuvant Treatment in Non-Small-Cell Lung Cancer.

Allen AM, Shochat T, Flex D, Kramer MR, Zer A, Peled N, Dudnik E, Fenig E, Saute M.

Oncology. 2018;95(1):13-19. doi: 10.1159/000487928. Epub 2018 Apr 20.


Pembrolizumab plus Chemotherapy in Metastatic Non-Small-Cell Lung Cancer.

Gandhi L, Rodríguez-Abreu D, Gadgeel S, Esteban E, Felip E, De Angelis F, Domine M, Clingan P, Hochmair MJ, Powell SF, Cheng SY, Bischoff HG, Peled N, Grossi F, Jennens RR, Reck M, Hui R, Garon EB, Boyer M, Rubio-Viqueira B, Novello S, Kurata T, Gray JE, Vida J, Wei Z, Yang J, Raftopoulos H, Pietanza MC, Garassino MC; KEYNOTE-189 Investigators.

N Engl J Med. 2018 May 31;378(22):2078-2092. doi: 10.1056/NEJMoa1801005. Epub 2018 Apr 16.



Brenner R, Ben-Zvi I, Shinar Y, Livneh A, Liphshitz I, Silverman B, Peled N, Levy C, Ben-Chetrit E, Kivity S.

Arthritis Rheumatol. 2018 Jul;70(7):1167-1168. doi: 10.1002/art.40496. Epub 2018 May 14. No abstract available.


The earliest modern humans outside Africa.

Hershkovitz I, Weber GW, Quam R, Duval M, Grün R, Kinsley L, Ayalon A, Bar-Matthews M, Valladas H, Mercier N, Arsuaga JL, Martinón-Torres M, Bermúdez de Castro JM, Fornai C, Martín-Francés L, Sarig R, May H, Krenn VA, Slon V, Rodríguez L, García R, Lorenzo C, Carretero JM, Frumkin A, Shahack-Gross R, Bar-Yosef Mayer DE, Cui Y, Wu X, Peled N, Groman-Yaroslavski I, Weissbrod L, Yeshurun R, Tsatskin A, Zaidner Y, Weinstein-Evron M.

Science. 2018 Jan 26;359(6374):456-459. doi: 10.1126/science.aap8369.


A molecular signature of lung cancer: potential biomarkers for adenocarcinoma and squamous cell carcinoma.

Shoshan-Barmatz V, Bishitz Y, Paul A, Krelin Y, Nakdimon I, Peled N, Lavon A, Rudoy-Zilberman E, Refaely Y.

Oncotarget. 2017 Nov 6;8(62):105492-105509. doi: 10.18632/oncotarget.22298. eCollection 2017 Dec 1.

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