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Items: 31

1.

Microbiota-derived lantibiotic restores resistance against vancomycin-resistant Enterococcus.

Kim SG, Becattini S, Moody TU, Shliaha PV, Littmann ER, Seok R, Gjonbalaj M, Eaton V, Fontana E, Amoretti L, Wright R, Caballero S, Wang ZX, Jung HJ, Morjaria SM, Leiner IM, Qin W, Ramos RJJF, Cross JR, Narushima S, Honda K, Peled JU, Hendrickson RC, Taur Y, van den Brink MRM, Pamer EG.

Nature. 2019 Aug;572(7771):665-669. doi: 10.1038/s41586-019-1501-z. Epub 2019 Aug 21.

PMID:
31435014
2.

Minimal residual disease negativity in multiple myeloma is associated with intestinal microbiota composition.

Pianko MJ, Devlin SM, Littmann ER, Chansakul A, Mastey D, Salcedo M, Fontana E, Ling L, Tavitian E, Slingerland JB, Slingerland AE, Clurman A, Gomes ALC, Taur Y, Pamer EG, Peled JU, van den Brink MRM, Landgren O, Lesokhin AM.

Blood Adv. 2019 Jul 9;3(13):2040-2044. doi: 10.1182/bloodadvances.2019032276.

3.

Antibiotic-Induced Shifts in Fecal Microbiota Density and Composition during Hematopoietic Stem Cell Transplantation.

Morjaria S, Schluter J, Taylor BP, Littmann ER, Carter RA, Fontana E, Peled JU, van den Brink MRM, Xavier JB, Taur Y.

Infect Immun. 2019 Aug 21;87(9). pii: e00206-19. doi: 10.1128/IAI.00206-19. Print 2019 Sep.

4.

Diversification and Evolution of Vancomycin-Resistant Enterococcus faecium during Intestinal Domination.

Dubin KA, Mathur D, McKenney PT, Taylor BP, Littmann ER, Peled JU, van den Brink MRM, Taur Y, Pamer EG, Xavier JB.

Infect Immun. 2019 Jun 20;87(7). pii: e00102-19. doi: 10.1128/IAI.00102-19. Print 2019 Jul.

5.

Inhibiting antibiotic-resistant Enterobacteriaceae by microbiota-mediated intracellular acidification.

Sorbara MT, Dubin K, Littmann ER, Moody TU, Fontana E, Seok R, Leiner IM, Taur Y, Peled JU, van den Brink MRM, Litvak Y, Bäumler AJ, Chaubard JL, Pickard AJ, Cross JR, Pamer EG.

J Exp Med. 2019 Jan 7;216(1):84-98. doi: 10.1084/jem.20181639. Epub 2018 Dec 18.

6.

Survival signal REG3α prevents crypt apoptosis to control acute gastrointestinal graft-versus-host disease.

Zhao D, Kim YH, Jeong S, Greenson JK, Chaudhry MS, Hoepting M, Anderson ER, van den Brink MR, Peled JU, Gomes AL, Slingerland AE, Donovan MJ, Harris AC, Levine JE, Ozbek U, Hooper LV, Stappenbeck TS, Ver Heul A, Liu TC, Reddy P, Ferrara JL.

J Clin Invest. 2018 Nov 1;128(11):4970-4979. doi: 10.1172/JCI99261. Epub 2018 Sep 24.

7.

Impact of gut colonization with butyrate-producing microbiota on respiratory viral infection following allo-HCT.

Haak BW, Littmann ER, Chaubard JL, Pickard AJ, Fontana E, Adhi F, Gyaltshen Y, Ling L, Morjaria SM, Peled JU, van den Brink MR, Geyer AI, Cross JR, Pamer EG, Taur Y.

Blood. 2018 Jun 28;131(26):2978-2986. doi: 10.1182/blood-2018-01-828996. Epub 2018 Apr 19.

8.

Third-party fecal microbiota transplantation following allo-HCT reconstitutes microbiome diversity.

DeFilipp Z, Peled JU, Li S, Mahabamunuge J, Dagher Z, Slingerland AE, Del Rio C, Valles B, Kempner ME, Smith M, Brown J, Dey BR, El-Jawahri A, McAfee SL, Spitzer TR, Ballen KK, Sung AD, Dalton TE, Messina JA, Dettmer K, Liebisch G, Oefner P, Taur Y, Pamer EG, Holler E, Mansour MK, van den Brink MRM, Hohmann E, Jenq RR, Chen YB.

Blood Adv. 2018 Apr 10;2(7):745-753. doi: 10.1182/bloodadvances.2018017731.

9.

Nutritional Support from the Intestinal Microbiota Improves Hematopoietic Reconstitution after Bone Marrow Transplantation in Mice.

Staffas A, Burgos da Silva M, Slingerland AE, Lazrak A, Bare CJ, Holman CD, Docampo MD, Shono Y, Durham B, Pickard AJ, Cross JR, Stein-Thoeringer C, Velardi E, Tsai JJ, Jahn L, Jay H, Lieberman S, Smith OM, Pamer EG, Peled JU, Cohen DE, Jenq RR, van den Brink MRM.

Cell Host Microbe. 2018 Apr 11;23(4):447-457.e4. doi: 10.1016/j.chom.2018.03.002. Epub 2018 Mar 22.

10.

Severe pembrolizumab-associated neutropenia after CD34+ selected allogeneic hematopoietic-cell transplantation for multiple myeloma.

Bryant AR, Perales MA, Tamari R, Peled JU, Giralt S.

Bone Marrow Transplant. 2018 Aug;53(8):1065-1068. doi: 10.1038/s41409-018-0142-4. Epub 2018 Mar 7. No abstract available.

PMID:
29515248
11.

The Microbiome and Hematopoietic Cell Transplantation: Past, Present, and Future.

Andermann TM, Peled JU, Ho C, Reddy P, Riches M, Storb R, Teshima T, van den Brink MRM, Alousi A, Balderman S, Chiusolo P, Clark WB, Holler E, Howard A, Kean LS, Koh AY, McCarthy PL, McCarty JM, Mohty M, Nakamura R, Rezvani K, Segal BH, Shaw BE, Shpall EJ, Sung AD, Weber D, Whangbo J, Wingard JR, Wood WA, Perales MA, Jenq RR, Bhatt AS; Blood and Marrow Transplant Clinical Trials Network.

Biol Blood Marrow Transplant. 2018 Jul;24(7):1322-1340. doi: 10.1016/j.bbmt.2018.02.009. Epub 2018 Feb 19. Review. No abstract available.

12.

Unlocking the Complex Flavors of Dysgeusia after Hematopoietic Cell Transplantation.

Scordo M, Shah GL, Peled JU, Preston EV, Buchan ML, Epstein JB, Barasch A, Giralt SA.

Biol Blood Marrow Transplant. 2018 Mar;24(3):425-432. doi: 10.1016/j.bbmt.2017.10.022. Epub 2017 Oct 16. Review.

13.

Intestinal Microbiota and Relapse After Hematopoietic-Cell Transplantation.

Peled JU, Devlin SM, Staffas A, Lumish M, Khanin R, Littmann ER, Ling L, Kosuri S, Maloy M, Slingerland JB, Ahr KF, Porosnicu Rodriguez KA, Shono Y, Slingerland AE, Docampo MD, Sung AD, Weber D, Alousi AM, Gyurkocza B, Ponce DM, Barker JN, Perales MA, Giralt SA, Taur Y, Pamer EG, Jenq RR, van den Brink MRM.

J Clin Oncol. 2017 May 20;35(15):1650-1659. doi: 10.1200/JCO.2016.70.3348. Epub 2017 Mar 15.

14.

Microbiota Disruption Induced by Early Use of Broad-Spectrum Antibiotics Is an Independent Risk Factor of Outcome after Allogeneic Stem Cell Transplantation.

Weber D, Jenq RR, Peled JU, Taur Y, Hiergeist A, Koestler J, Dettmer K, Weber M, Wolff D, Hahn J, Pamer EG, Herr W, Gessner A, Oefner PJ, van den Brink MRM, Holler E.

Biol Blood Marrow Transplant. 2017 May;23(5):845-852. doi: 10.1016/j.bbmt.2017.02.006. Epub 2017 Feb 14.

15.

Role of the intestinal mucosa in acute gastrointestinal GVHD.

Peled JU, Hanash AM, Jenq RR.

Hematology Am Soc Hematol Educ Program. 2016 Dec 2;2016(1):119-127. Review.

16.

Role of the intestinal mucosa in acute gastrointestinal GVHD.

Peled JU, Hanash AM, Jenq RR.

Blood. 2016 Nov 17;128(20):2395-2402. Review.

17.

Not just leukemia: CMV may protect against lymphoma recurrence after allogeneic transplant.

Peled JU, Jenq RR.

Leuk Lymphoma. 2017 Apr;58(4):759-761. doi: 10.1080/10428194.2016.1239265. Epub 2016 Oct 12. No abstract available.

18.

Role of gut flora after bone marrow transplantation.

Peled JU, Jenq RR, Holler E, van den Brink MR.

Nat Microbiol. 2016 Mar 29;1:16036. doi: 10.1038/nmicrobiol.2016.36. No abstract available.

19.

Increased GVHD-related mortality with broad-spectrum antibiotic use after allogeneic hematopoietic stem cell transplantation in human patients and mice.

Shono Y, Docampo MD, Peled JU, Perobelli SM, Velardi E, Tsai JJ, Slingerland AE, Smith OM, Young LF, Gupta J, Lieberman SR, Jay HV, Ahr KF, Porosnicu Rodriguez KA, Xu K, Calarfiore M, Poeck H, Caballero S, Devlin SM, Rapaport F, Dudakov JA, Hanash AM, Gyurkocza B, Murphy GF, Gomes C, Liu C, Moss EL, Falconer SB, Bhatt AS, Taur Y, Pamer EG, van den Brink MRM, Jenq RR.

Sci Transl Med. 2016 May 18;8(339):339ra71. doi: 10.1126/scitranslmed.aaf2311.

20.

Intestinal Blautia Is Associated with Reduced Death from Graft-versus-Host Disease.

Jenq RR, Taur Y, Devlin SM, Ponce DM, Goldberg JD, Ahr KF, Littmann ER, Ling L, Gobourne AC, Miller LC, Docampo MD, Peled JU, Arpaia N, Cross JR, Peets TK, Lumish MA, Shono Y, Dudakov JA, Poeck H, Hanash AM, Barker JN, Perales MA, Giralt SA, Pamer EG, van den Brink MR.

Biol Blood Marrow Transplant. 2015 Aug;21(8):1373-83. doi: 10.1016/j.bbmt.2015.04.016. Epub 2015 May 11.

21.

Intestinal microbiota-related effects on graft-versus-host disease.

Shono Y, Docampo MD, Peled JU, Perobelli SM, Jenq RR.

Int J Hematol. 2015 May;101(5):428-37. doi: 10.1007/s12185-015-1781-5. Epub 2015 Mar 27. Review.

22.

Msh6 protects mature B cells from lymphoma by preserving genomic stability.

Peled JU, Sellers RS, Iglesias-Ussel MD, Shin DM, Montagna C, Zhao C, Li Z, Edelmann W, Morse HC 3rd, Scharff MD.

Am J Pathol. 2010 Nov;177(5):2597-608. doi: 10.2353/ajpath.2010.100234. Epub 2010 Oct 7.

23.

MSH2/MSH6 complex promotes error-free repair of AID-induced dU:G mispairs as well as error-prone hypermutation of A:T sites.

Roa S, Li Z, Peled JU, Zhao C, Edelmann W, Scharff MD.

PLoS One. 2010 Jun 17;5(6):e11182. doi: 10.1371/journal.pone.0011182.

24.

Requirement for cyclin D3 in germinal center formation and function.

Peled JU, Yu JJ, Venkatesh J, Bi E, Ding BB, Krupski-Downs M, Shaknovich R, Sicinski P, Diamond B, Scharff MD, Ye BH.

Cell Res. 2010 Jun;20(6):631-46. doi: 10.1038/cr.2010.55. Epub 2010 Apr 20.

25.

Do electronic health records help or hinder medical education?

Peled JU, Sagher O, Morrow JB, Dobbie AE.

PLoS Med. 2009 May 5;6(5):e1000069. doi: 10.1371/journal.pmed.1000069. Epub 2009 May 12.

26.

Ubiquitylated PCNA plays a role in somatic hypermutation and class-switch recombination and is required for meiotic progression.

Roa S, Avdievich E, Peled JU, Maccarthy T, Werling U, Kuang FL, Kan R, Zhao C, Bergman A, Cohen PE, Edelmann W, Scharff MD.

Proc Natl Acad Sci U S A. 2008 Oct 21;105(42):16248-53. doi: 10.1073/pnas.0808182105. Epub 2008 Oct 14.

27.

The biochemistry of somatic hypermutation.

Peled JU, Kuang FL, Iglesias-Ussel MD, Roa S, Kalis SL, Goodman MF, Scharff MD.

Annu Rev Immunol. 2008;26:481-511. doi: 10.1146/annurev.immunol.26.021607.090236. Review.

PMID:
18304001
28.

Targeting AID to the Ig genes.

Li Z, Luo Z, Ronai D, Kuang FL, Peled JU, Iglesias-Ussel MD, Scharff MD.

Adv Exp Med Biol. 2007;596:93-109. Review. No abstract available.

PMID:
17338179
29.

A role for Mlh3 in somatic hypermutation.

Li Z, Peled JU, Zhao C, Svetlanov A, Ronai D, Cohen PE, Scharff MD.

DNA Repair (Amst). 2006 Jun 10;5(6):675-82. Epub 2006 Mar 27.

PMID:
16564751
30.

Examination of Msh6- and Msh3-deficient mice in class switching reveals overlapping and distinct roles of MutS homologues in antibody diversification.

Li Z, Scherer SJ, Ronai D, Iglesias-Ussel MD, Peled JU, Bardwell PD, Zhuang M, Lee K, Martin A, Edelmann W, Scharff MD.

J Exp Med. 2004 Jul 5;200(1):47-59.

31.

Psychosocial counseling may be best treatment for hair loss.

Peled JU.

Am Fam Physician. 2004 Mar 15;69(6):1362. No abstract available.

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