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Comparative Immunogenicity of Several Enhanced Influenza Vaccine Options for Older Adults: A Randomized, Controlled Trial.

Cowling BJ, Perera RAPM, Valkenburg SA, Leung NHL, Iuliano AD, Tam YH, Wong JHF, Fang VJ, Li APY, So HC, Ip DKM, Azziz-Baumgartner E, Fry AM, Levine MZ, Gangappa S, Sambhara S, Barr IG, Skowronski DM, Peiris JSM, Thompson MG.

Clin Infect Dis. 2019 Dec 12. pii: ciz1034. doi: 10.1093/cid/ciz1034. [Epub ahead of print]


Cross-reactive antibody-dependent cellular cytotoxicity antibodies are increased by recent infection in a household study of influenza transmission.

Valkenburg SA, Fang VJ, Leung NH, Chu DK, Ip DK, Perera RA, Wang Y, Li AP, Peiris JM, Cowling BJ, Poon LL.

Clin Transl Immunology. 2019 Nov 20;8(11):e1092. doi: 10.1002/cti2.1092. eCollection 2019.


Vaccine-induced T cell protection from influenza viruses.

Valkenburg SA, Li OTW, Peiris JSM, Perera LP, Poon LLM.

Hong Kong Med J. 2019 Oct;25 Suppl 7(7):33-36. No abstract available.


Influenza virus infections in Hong Kong in 2013-14: a community-based longitudinal seroepidemiological study.

Cowling BJ, Peiris JSM, Kwok KO.

Hong Kong Med J. 2019 Oct;25 Suppl 7(5):23-26. No abstract available.


Maternal antibodies against influenza in cord blood and protection against laboratory-confirmed influenza in infants.

Cowling BJ, Perera RAPM, Fang VJ, Chu DKW, Hui APW, Yeung APC, Peiris JSM, Wong WHS, Chan ELY, Chiu SS.

Clin Infect Dis. 2019 Oct 29. pii: ciz1058. doi: 10.1093/cid/ciz1058. [Epub ahead of print]


Reply to 'Reconciling disparate estimates of viral genetic diversity during human influenza infections'.

Poon LLM, Song T, Wentworth DE, Holmes EC, Greenbaum BD, Peiris JSM, Cowling BJ, Ghedin E.

Nat Genet. 2019 Sep;51(9):1301-1303. doi: 10.1038/s41588-019-0486-8. No abstract available.


Effectiveness of Partial and Full Influenza Vaccination Among Children Aged <9 Years in Hong Kong, 2011-2019.

Chua H, Chiu SS, Chan ELY, Feng S, Kwan MYW, Wong JSC, Peiris JSM, Cowling BJ.

J Infect Dis. 2019 Oct 8;220(10):1568-1576. doi: 10.1093/infdis/jiz361.


The Effect of Influenza Vaccination History on Changes in Hemagglutination Inhibition Titers After Receipt of the 2015-2016 Influenza Vaccine in Older Adults in Hong Kong.

Ng TWY, Perera RAPM, Fang VJ, Yau EM, Peiris JSM, Tam YH, Cowling BJ.

J Infect Dis. 2020 Jan 1;221(1):33-41. doi: 10.1093/infdis/jiz327.


Seroprevalence of dogs in Hong Kong to human and canine influenza viruses.

Su W, Kinoshita R, Gray J, Ji Y, Yu D, Peiris JSM, Yen HL.

Vet Rec Open. 2019 Apr 11;6(1):e000327. doi: 10.1136/vetreco-2018-000327. eCollection 2019.


Tropism of influenza B viruses in human respiratory tract explants and airway organoids.

Bui CHT, Chan RWY, Ng MMT, Cheung MC, Ng KC, Chan MPK, Chan LLY, Fong JHM, Nicholls JM, Peiris JSM, Chan MCW.

Eur Respir J. 2019 Aug 15;54(2). pii: 1900008. doi: 10.1183/13993003.00008-2019. Print 2019 Aug.


Risk Assessment of the Tropism and Pathogenesis of the Highly Pathogenic Avian Influenza A/H7N9 Virus Using Ex Vivo and In Vitro Cultures of Human Respiratory Tract.

Chan LLY, Hui KPY, Kuok DIT, Bui CHT, Ng KC, Mok CKP, Yang ZF, Guan W, Poon LLM, Zhong N, Peiris JSM, Nicholls JM, Chan MCW.

J Infect Dis. 2019 Jul 19;220(4):578-588. doi: 10.1093/infdis/jiz165.


Age-specific differences in the dynamics of protective immunity to influenza.

Ranjeva S, Subramanian R, Fang VJ, Leung GM, Ip DKM, Perera RAPM, Peiris JSM, Cowling BJ, Cobey S.

Nat Commun. 2019 Apr 10;10(1):1660. doi: 10.1038/s41467-019-09652-6.


Neuraminidase activity and specificity of influenza A virus are influenced by haemagglutinin-receptor binding.

Lai JCC, Karunarathna HMTK, Wong HH, Peiris JSM, Nicholls JM.

Emerg Microbes Infect. 2019;8(1):327-338. doi: 10.1080/22221751.2019.1581034.


Smoking and Influenza-associated Morbidity and Mortality: A Systematic Review and Meta-analysis.

Han L, Ran J, Mak YW, Suen LK, Lee PH, Peiris JSM, Yang L.

Epidemiology. 2019 May;30(3):405-417. doi: 10.1097/EDE.0000000000000984.


Comparison of influenza disease burden in older populations of Hong Kong and Brisbane: the impact of influenza and pneumococcal vaccination.

Yang L, Chan KP, Wong CM, Chiu SSS, Magalhaes RJS, Thach TQ, Peiris JSM, Clements ACA, Hu W.

BMC Infect Dis. 2019 Feb 14;19(1):162. doi: 10.1186/s12879-019-3735-7.


Early season estimate of influenza vaccination effectiveness against influenza hospitalisation in children, Hong Kong, winter influenza season 2018/19.

Chiu SS, Kwan MY, Feng S, Chan EL, Chua H, Wong JS, Peiris JM, Cowling BJ.

Euro Surveill. 2019 Jan;24(5). doi: 10.2807/1560-7917.ES.2019.24.5.1900056.


Indirect protection from vaccinating children against influenza in households.

Tsang TK, Fang VJ, Ip DKM, Perera RAPM, So HC, Leung GM, Peiris JSM, Cowling BJ, Cauchemez S.

Nat Commun. 2019 Jan 10;10(1):106. doi: 10.1038/s41467-018-08036-6.


Estimation of excess mortality and hospitalisation associated with the 2009 pandemic influenza.

Yang L, Wong CM, Chiu SS, Cowling BJ, Peiris JS.

Hong Kong Med J. 2018 Oct;24 Suppl 6(5):19-22. No abstract available.


Influenza-like illness and viral aetiology in Hong Kong children.

Cowling BJ, Chan KH, Peiris JS.

Hong Kong Med J. 2018 Oct;24 Suppl 6(5):12-15. No abstract available.


Influenza Hemagglutination-inhibition Antibody Titer as a Mediator of Vaccine-induced Protection for Influenza B.

Cowling BJ, Lim WW, Perera RAPM, Fang VJ, Leung GM, Peiris JSM, Tchetgen Tchetgen EJ.

Clin Infect Dis. 2019 May 2;68(10):1713-1717. doi: 10.1093/cid/ciy759.


Therapeutic Implications of Human Umbilical Cord Mesenchymal Stromal Cells in Attenuating Influenza A(H5N1) Virus-Associated Acute Lung Injury.

Loy H, Kuok DIT, Hui KPY, Choi MHL, Yuen W, Nicholls JM, Peiris JSM, Chan MCW.

J Infect Dis. 2019 Jan 7;219(2):186-196. doi: 10.1093/infdis/jiy478. Erratum in: J Infect Dis. 2019 Jan 7;219(2):339.


Tropism, replication competence, and innate immune responses of influenza virus: an analysis of human airway organoids and ex-vivo bronchus cultures.

Hui KPY, Ching RHH, Chan SKH, Nicholls JM, Sachs N, Clevers H, Peiris JSM, Chan MCW.

Lancet Respir Med. 2018 Nov;6(11):846-854. doi: 10.1016/S2213-2600(18)30236-4. Epub 2018 Jul 11.


Avian influenza A H7N9 virus infects human astrocytes and neuronal cells and induces inflammatory immune responses.

Ng YP, Yip TF, Peiris JSM, Ip NY, Lee SMY.

J Neurovirol. 2018 Dec;24(6):752-760. doi: 10.1007/s13365-018-0659-8. Epub 2018 Jul 9.


Incidence of influenza A(H3N2) virus infections in Hong Kong in a longitudinal sero-epidemiological study, 2009-2015.

Wei VWI, Wong JYT, Perera RAPM, Kwok KO, Fang VJ, Barr IG, Peiris JSM, Riley S, Cowling BJ.

PLoS One. 2018 May 24;13(5):e0197504. doi: 10.1371/journal.pone.0197504. eCollection 2018.


Effect of interferon alpha and cyclosporine treatment separately and in combination on Middle East Respiratory Syndrome Coronavirus (MERS-CoV) replication in a human in-vitro and ex-vivo culture model.

Li HS, Kuok DIT, Cheung MC, Ng MMT, Ng KC, Hui KPY, Peiris JSM, Chan MCW, Nicholls JM.

Antiviral Res. 2018 Jul;155:89-96. doi: 10.1016/j.antiviral.2018.05.007. Epub 2018 May 17.


Recognition of Double-Stranded RNA and Regulation of Interferon Pathway by Toll-Like Receptor 10.

Lee SM, Yip TF, Yan S, Jin DY, Wei HL, Guo RT, Peiris JSM.

Front Immunol. 2018 Mar 16;9:516. doi: 10.3389/fimmu.2018.00516. eCollection 2018.


Coronaviruses in guano from Pteropus medius bats in Peradeniya, Sri Lanka.

Kudagammana HDWS, Thevanesam V, Chu DKW, Eriyagama NB, Peiris JSM, Noordeen F.

Transbound Emerg Dis. 2018 Aug;65(4):1122-1124. doi: 10.1111/tbed.12851. Epub 2018 Mar 2.


Interim estimate of influenza vaccine effectiveness in hospitalised children, Hong Kong, 2017/18.

Chiu SS, Kwan MYW, Feng S, Wong JSC, Leung CW, Chan ELY, Peiris JSM, Cowling BJ.

Euro Surveill. 2018 Feb;23(8). doi: 10.2807/1560-7917.ES.2018.23.8.18-00062.


Use of influenza antivirals in patients hospitalized in Hong Kong, 2000-2015.

Cowling BJ, Chui CSL, Lim WW, Wu P, Hui CKM, Peiris JSM, Chan EW.

PLoS One. 2018 Jan 19;13(1):e0190306. doi: 10.1371/journal.pone.0190306. eCollection 2018.


Influenza Vaccine Effectiveness Against Influenza A(H3N2) Hospitalizations in Children in Hong Kong in a Prolonged Season, 2016/2017.

Chiu SS, Kwan MYW, Feng S, Wong JSC, Leung CW, Chan ELY, Chan KH, Ng TK, To WK, Cowling BJ, Peiris JSM.

J Infect Dis. 2018 Apr 11;217(9):1365-1371. doi: 10.1093/infdis/jiy027.


Human Clade A/H5N6 Influenza Virus Lacks Mammalian Adaptation Markers and Does Not Transmit via the Airborne Route between Ferrets.

Herfst S, Mok CKP, van den Brand JMA, van der Vliet S, Rosu ME, Spronken MI, Yang Z, de Meulder D, Lexmond P, Bestebroer TM, Peiris JSM, Fouchier RAM, Richard M.

mSphere. 2018 Jan 3;3(1). pii: e00405-17. doi: 10.1128/mSphere.00405-17. eCollection 2018 Jan-Feb.


Immune Responses to Twice-Annual Influenza Vaccination in Older Adults in Hong Kong.

Tam YH, Valkenburg SA, Perera RAPM, Wong JHF, Fang VJ, Ng TWY, Kwong ASK, Tsui WWS, Ip DKM, Poon LLM, Chau CKV, Barr IG, Peiris JSM, Cowling BJ.

Clin Infect Dis. 2018 Mar 5;66(6):904-912. doi: 10.1093/cid/cix900.


Monitoring Avian Influenza Viruses from Chicken Carcasses Sold at Markets, China, 2016.

Mao X, Wu J, Lau EHY, Cheng KL, Zhong Z, Song Y, Ji X, Zou L, Ke C, Peiris JSM, Wang H, Yen HL.

Emerg Infect Dis. 2017 Oct;23(10). doi: 10.3201/eid2310.170679. Epub 2017 Oct 17.


Replication of H9 influenza viruses in the human ex vivo respiratory tract, and the influence of neuraminidase on virus release.

Chan RWY, Chan LLY, Mok CKP, Lai J, Tao KP, Obadan A, Chan MCW, Perez DR, Peiris JSM, Nicholls JM.

Sci Rep. 2017 Jul 24;7(1):6208. doi: 10.1038/s41598-017-05853-5.


Human Infection with Highly Pathogenic Avian Influenza A(H7N9) Virus, China.

Ke C, Mok CKP, Zhu W, Zhou H, He J, Guan W, Wu J, Song W, Wang D, Liu J, Lin Q, Chu DKW, Yang L, Zhong N, Yang Z, Shu Y, Peiris JSM.

Emerg Infect Dis. 2017 Jul;23(8):1332-1340. doi: 10.3201/eid2308.170600. Epub 2017 Aug 15.


The PB2 mutation with lysine at 627 enhances the pathogenicity of avian influenza (H7N9) virus which belongs to a non-zoonotic lineage.

Li W, Lee HHY, Li RF, Zhu HM, Yi G, Peiris JSM, Yang ZF, Mok CKP.

Sci Rep. 2017 May 24;7(1):2352. doi: 10.1038/s41598-017-02598-z.


Population-Based Pediatric Hospitalization Burden of Lineage-Specific Influenza B in Hong Kong, 2004-2014.

Cowling BJ, Wu P, Lo JYC, Chan KH, Chan ELY, Fang VJ, So LY, Peiris JSM, Chiu SS.

Clin Infect Dis. 2017 Jul 15;65(2):300-307. doi: 10.1093/cid/cix312.


Tropism and innate host responses of influenza A/H5N6 virus: an analysis of ex vivo and in vitro cultures of the human respiratory tract.

Hui KP, Chan LL, Kuok DI, Mok CK, Yang ZF, Li RF, Luk GS, Lee EF, Lai JC, Yen HL, Zhu H, Guan Y, Nicholls JM, Peiris JS, Chan MC.

Eur Respir J. 2017 Mar 8;49(3). pii: 1601710. doi: 10.1183/13993003.01710-2016. Print 2017 Mar.


Avian influenza virus directly infects human natural killer cells and inhibits cell activity.

Mao H, Liu Y, Sia SF, Peiris JSM, Lau YL, Tu W.

Virol Sin. 2017 Apr;32(2):122-129. doi: 10.1007/s12250-016-3918-y. Epub 2017 Feb 23.


H7N9 Influenza A Virus Exhibits Importin-α7-Mediated Replication in the Mammalian Respiratory Tract.

Bertram S, Thiele S, Dreier C, Resa-Infante P, Preuß A, van Riel D, Mok CKP, Schwalm F, Peiris JSM, Klenk HD, Gabriel G.

Am J Pathol. 2017 Apr;187(4):831-840. doi: 10.1016/j.ajpath.2016.12.017. Epub 2017 Feb 9.


Viral Shedding and Transmission Potential of Asymptomatic and Paucisymptomatic Influenza Virus Infections in the Community.

Ip DK, Lau LL, Leung NH, Fang VJ, Chan KH, Chu DK, Leung GM, Peiris JS, Uyeki TM, Cowling BJ.

Clin Infect Dis. 2017 Mar 15;64(6):736-742. doi: 10.1093/cid/ciw841.


Population seroprevalence of antibody to influenza A(H7N9) virus, Guangzhou, China.

Lin YP, Yang ZF, Liang Y, Li ZT, Bond HS, Chua H, Luo YS, Chen Y, Chen TT, Guan WD, Lai JCC, Siu YL, Pan SH, Peiris JSM, Cowling BJ, Mok CKP.

BMC Infect Dis. 2016 Nov 4;16(1):632. doi: 10.1186/s12879-016-1983-3. Erratum in: BMC Infect Dis. 2017 Apr 19;17 (1):286.


Serum 25-Hydroxyvitamin D Was Not Associated with Influenza Virus Infection in Children and Adults in Hong Kong, 2009-2010.

Xu C, Fang VJ, Perera RA, Kam AM, Ng S, Chan YH, Chan KH, Ip DK, Peiris JM, Cowling BJ.

J Nutr. 2016 Dec;146(12):2506-2512. Epub 2016 Oct 26.


CLEC5A-Mediated Enhancement of the Inflammatory Response in Myeloid Cells Contributes to Influenza Virus Pathogenicity In Vivo.

Teng O, Chen ST, Hsu TL, Sia SF, Cole S, Valkenburg SA, Hsu TY, Zheng JT, Tu W, Bruzzone R, Peiris JSM, Hsieh SL, Yen HL.

J Virol. 2016 Dec 16;91(1). pii: e01813-16. doi: 10.1128/JVI.01813-16. Print 2017 Jan 1.


MERS-CoV at the Animal-Human Interface: Inputs on Exposure Pathways from an Expert-Opinion Elicitation.

Funk AL, Goutard FL, Miguel E, Bourgarel M, Chevalier V, Faye B, Peiris JS, Van Kerkhove MD, Roger FL.

Front Vet Sci. 2016 Oct 5;3:88. eCollection 2016.


Evaluation of the human adaptation of influenza A/H7N9 virus in PB2 protein using human and swine respiratory tract explant cultures.

Chan LL, Bui CT, Mok CK, Ng MM, Nicholls JM, Peiris JS, Chan MC, Chan RW.

Sci Rep. 2016 Oct 14;6:35401. doi: 10.1038/srep35401.


Isolation of H5N6, H7N9 and H9N2 avian influenza A viruses from air sampled at live poultry markets in China, 2014 and 2015.

Zhou J, Wu J, Zeng X, Huang G, Zou L, Song Y, Gopinath D, Zhang X, Kang M, Lin J, Cowling BJ, Lindsley WG, Ke C, Peiris JS, Yen HL.

Euro Surveill. 2016 Sep 1;21(35). doi: 10.2807/1560-7917.ES.2016.21.35.30331.


Age-specific genetic and antigenic variations of influenza A viruses in Hong Kong, 2013-2014.

Cao P, Wong CM, Chan KH, Wang X, Chan KP, Peiris JS, Poon LL, Yang L.

Sci Rep. 2016 Jul 25;6:30260. doi: 10.1038/srep30260.

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