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Molecular diagnosis of vaginitis: comparing qPCR and microbiome profiling approaches to current microscopy scoring.

Lynch T, Peirano G, Lloyd T, Read R, Carter J, Chu A, Shaman JA, Jarvis JP, Diamond E, Ijaz UZ, Church D.

J Clin Microbiol. 2019 Jul 17. pii: JCM.00300-19. doi: 10.1128/JCM.00300-19. [Epub ahead of print]


Genomic and Functional Analysis of Emerging Virulent and Multidrug-Resistant Escherichia coli Lineage Sequence Type 648.

Schaufler K, Semmler T, Wieler LH, Trott DJ, Pitout J, Peirano G, Bonnedahl J, Dolejska M, Literak I, Fuchs S, Ahmed N, Grobbel M, Torres C, McNally A, Pickard D, Ewers C, Croucher NJ, Corander J, Guenther S.

Antimicrob Agents Chemother. 2019 May 24;63(6). pii: e00243-19. doi: 10.1128/AAC.00243-19. Print 2019 Jun.


Klebsiella pneumoniae ST307 with blaOXA-181, South Africa, 2014-2016.

Lowe M, Kock MM, Coetzee J, Hoosien E, Peirano G, Strydom KA, Ehlers MM, Mbelle NM, Shashkina E, Haslam DB, Dhawan P, Donnelly RJ, Chen L, Kreiswirth BN, Pitout JDD.

Emerg Infect Dis. 2019 Apr;25(4):739-747. doi: 10.3201/eid2504.181482.


Hospitalized Pets as a Source of Carbapenem-Resistance.

Gentilini F, Turba ME, Pasquali F, Mion D, Romagnoli N, Zambon E, Terni D, Peirano G, Pitout JDD, Parisi A, Sambri V, Zanoni RG.

Front Microbiol. 2018 Dec 6;9:2872. doi: 10.3389/fmicb.2018.02872. eCollection 2018.


A Fatal Bacteremia Caused by Hypermucousviscous KPC-2 Producing Extensively Drug-Resistant K64-ST11 Klebsiella pneumoniae in Brazil.

de Campos TA, Gonçalves LF, Magalhães KG, de Paulo Martins V, Pappas Júnior GJ, Peirano G, Pitout JDD, Gonçalves GB, Furlan JPR, Stehling EG, Pitondo-Silva A.

Front Med (Lausanne). 2018 Sep 21;5:265. doi: 10.3389/fmed.2018.00265. eCollection 2018.


Epidemiological and genomic characterization of community-acquired Clostridium difficile infections.

Thornton CS, Rubin JE, Greninger AL, Peirano G, Chiu CY, Pillai DR.

BMC Infect Dis. 2018 Aug 31;18(1):443. doi: 10.1186/s12879-018-3337-9.


Genomic characterization of IMP and VIM carbapenemase-encoding transferable plasmids of Enterobacteriaceae.

Matsumura Y, Peirano G, Bradford PA, Motyl MR, DeVinney R, Pitout JDD.

J Antimicrob Chemother. 2018 Nov 1;73(11):3034-3038. doi: 10.1093/jac/dky303.


Acinetobacter baumannii: Epidemiological and Beta-Lactamase Data From Two Tertiary Academic Hospitals in Tshwane, South Africa.

Lowe M, Ehlers MM, Ismail F, Peirano G, Becker PJ, Pitout JDD, Kock MM.

Front Microbiol. 2018 Jun 12;9:1280. doi: 10.3389/fmicb.2018.01280. eCollection 2018.


The population structure of clinical extra-intestinal Escherichia coli in a teaching hospital from Nigeria.

Seni J, Peirano G, Okon KO, Jibrin YB, Mohammed A, Mshana SE, DeVinney R, Pitout JDD.

Diagn Microbiol Infect Dis. 2018 Sep;92(1):46-49. doi: 10.1016/j.diagmicrobio.2018.04.001. Epub 2018 Apr 14.


Complete Genome Sequence of Escherichia coli J53, an Azide-Resistant Laboratory Strain Used for Conjugation Experiments.

Matsumura Y, Peirano G, Pitout JDD.

Genome Announc. 2018 May 24;6(21). pii: e00433-18. doi: 10.1128/genomeA.00433-18.


Genomic Epidemiology of Global Carbapenemase-Producing Enterobacter spp., 2008-2014.

Peirano G, Matsumura Y, Adams MD, Bradford P, Motyl M, Chen L, Kreiswirth BN, Pitout JDD.

Emerg Infect Dis. 2018 Jun;24(6):1010-1019. doi: 10.3201/eid2406.171648.


Rates of colonization with extended-spectrum β-lactamase-producing Escherichia coli in Canadian travellers returning from South Asia: a cross-sectional assessment.

Peirano G, Gregson DB, Kuhn S, Vanderkooi OG, Nobrega DB, Pitout JDD.

CMAJ Open. 2017 Dec 13;5(4):E850-E855. doi: 10.9778/cmajo.20170041. Epub 2017 Dec 15.


Genomic epidemiology of global Klebsiella pneumoniae carbapenemase (KPC)-producing Escherichia coli.

Stoesser N, Sheppard AE, Peirano G, Anson LW, Pankhurst L, Sebra R, Phan HTT, Kasarskis A, Mathers AJ, Peto TEA, Bradford P, Motyl MR, Walker AS, Crook DW, Pitout JD.

Sci Rep. 2017 Jul 19;7(1):5917. doi: 10.1038/s41598-017-06256-2.


Rapid Identification of Different Escherichia coli Sequence Type 131 Clades.

Matsumura Y, Pitout JDD, Peirano G, DeVinney R, Noguchi T, Yamamoto M, Gomi R, Matsuda T, Nakano S, Nagao M, Tanaka M, Ichiyama S.

Antimicrob Agents Chemother. 2017 Jul 25;61(8). pii: e00179-17. doi: 10.1128/AAC.00179-17. Print 2017 Aug.


Genomic epidemiology of global VIM-producing Enterobacteriaceae.

Matsumura Y, Peirano G, Devinney R, Bradford PA, Motyl MR, Adams MD, Chen L, Kreiswirth B, Pitout JDD.

J Antimicrob Chemother. 2017 Aug 1;72(8):2249-2258. doi: 10.1093/jac/dkx148.


Importance of Clonal Complex 258 and IncFK2-like Plasmids among a Global Collection of Klebsiella pneumoniae with blaKPC.

Peirano G, Bradford PA, Kazmierczak KM, Chen L, Kreiswirth BN, Pitout JD.

Antimicrob Agents Chemother. 2017 Mar 24;61(4). pii: e02610-16. doi: 10.1128/AAC.02610-16. Print 2017 Apr.


Global Molecular Epidemiology of IMP-Producing Enterobacteriaceae.

Matsumura Y, Peirano G, Motyl MR, Adams MD, Chen L, Kreiswirth B, DeVinney R, Pitout JD.

Antimicrob Agents Chemother. 2017 Mar 24;61(4). pii: e02729-16. doi: 10.1128/AAC.02729-16. Print 2017 Apr.


Global Escherichia coli Sequence Type 131 Clade with blaCTX-M-27 Gene.

Matsumura Y, Pitout JD, Gomi R, Matsuda T, Noguchi T, Yamamoto M, Peirano G, DeVinney R, Bradford PA, Motyl MR, Tanaka M, Nagao M, Takakura S, Ichiyama S.

Emerg Infect Dis. 2016 Nov;22(11):1900-1907. doi: 10.3201/eid2211.160519.


Complete Sequencing of Plasmids Containing blaOXA-163 and blaOXA-48 in Escherichia coli Sequence Type 131.

Stoesser N, Sheppard AE, Peirano G, Sebra R, Lynch T, Anson L, Kasarskis A, Motyl MR, Crook DW, Pitout JD.

Antimicrob Agents Chemother. 2016 Oct 21;60(11):6948-6951. doi: 10.1128/AAC.01130-16. Print 2016 Nov.


Molecular Evolution of a Klebsiella pneumoniae ST278 Isolate Harboring blaNDM-7 and Involved in Nosocomial Transmission.

Lynch T, Chen L, Peirano G, Gregson DB, Church DL, Conly J, Kreiswirth BN, Pitout JD.

J Infect Dis. 2016 Sep 1;214(5):798-806. doi: 10.1093/infdis/jiw240. Epub 2016 Jun 9.


First Report of blaIMP-14 on a Plasmid Harboring Multiple Drug Resistance Genes in Escherichia coli Sequence Type 131.

Stoesser N, Sheppard AE, Peirano G, Sebra RP, Lynch T, Anson LW, Kasarskis A, Motyl MR, Crook DW, Pitout JD.

Antimicrob Agents Chemother. 2016 Jul 22;60(8):5068-71. doi: 10.1128/AAC.00840-16. Print 2016 Aug.


Methadone as first-line opioid treatment for cancer pain in a developing country palliative care unit.

Peirano GP, Mammana GP, Bertolino MS, Pastrana T, Vega GF, Russo J, Varela G, Vignaroli E, Ruggiero R, Armesto A, Camerano G, Dran G.

Support Care Cancer. 2016 Aug;24(8):3551-6. doi: 10.1007/s00520-016-3191-5. Epub 2016 Mar 29.


Whole-Genome Sequencing Reveals the Origin and Rapid Evolution of an Emerging Outbreak Strain of Streptococcus pneumoniae 12F.

Deng X, Peirano G, Schillberg E, Mazzulli T, Gray-Owen SD, Wylie JL, Robinson DA, Mahmud SM, Pillai DR.

Clin Infect Dis. 2016 May 1;62(9):1126-1132. doi: 10.1093/cid/ciw050. Epub 2016 Feb 7.


Colistin-Nonsusceptible Pseudomonas aeruginosa Sequence Type 654 with blaNDM-1 Arrives in North America.

Mataseje LF, Peirano G, Church DL, Conly J, Mulvey M, Pitout JD.

Antimicrob Agents Chemother. 2016 Jan 11;60(3):1794-800. doi: 10.1128/AAC.02591-15.


Molecular Characterization by Using Next-Generation Sequencing of Plasmids Containing blaNDM-7 in Enterobacteriaceae from Calgary, Canada.

Chen L, Peirano G, Lynch T, Chavda KD, Gregson DB, Church DL, Conly J, Kreiswirth BN, Pitout JD.

Antimicrob Agents Chemother. 2015 Dec 7;60(3):1258-63. doi: 10.1128/AAC.02661-15.


The role of epidemic resistance plasmids and international high-risk clones in the spread of multidrug-resistant Enterobacteriaceae.

Mathers AJ, Peirano G, Pitout JD.

Clin Microbiol Rev. 2015 Jul;28(3):565-91. doi: 10.1128/CMR.00116-14. Review.


Escherichia coli ST131: The quintessential example of an international multiresistant high-risk clone.

Mathers AJ, Peirano G, Pitout JD.

Adv Appl Microbiol. 2015;90:109-54. doi: 10.1016/bs.aambs.2014.09.002. Epub 2014 Nov 13. Review.


Global incidence of carbapenemase-producing Escherichia coli ST131.

Peirano G, Bradford PA, Kazmierczak KM, Badal RE, Hackel M, Hoban DJ, Pitout JD.

Emerg Infect Dis. 2014 Nov;20(11):1928-31. doi: 10.3201/eid2011.141388.


Differences in risk-factor profiles between patients with ESBL-producing Escherichia coli and Klebsiella pneumoniae: a multicentre case-case comparison study.

Freeman JT, Rubin J, McAuliffe GN, Peirano G, Roberts SA, Drinković D, Pitout JD.

Antimicrob Resist Infect Control. 2014 Sep 1;3:27. doi: 10.1186/2047-2994-3-27. eCollection 2014.


NDM-1-producing Enterobacteriaceae from South Africa: moving towards endemicity?

Rubin JE, Peirano G, Peer AK, Govind CN, Pitout JD.

Diagn Microbiol Infect Dis. 2014 Jul;79(3):378-80. doi: 10.1016/j.diagmicrobio.2014.04.003. Epub 2014 Apr 24.


Outbreak of invasive Streptococcus pneumoniae serotype 12F among a marginalized inner-city population in Winnipeg, Canada, 2009-2011.

Schillberg E, Isaac M, Deng X, Peirano G, Wylie JL, Van Caeseele P, Pillai DR, Sinnock H, Mahmud SM.

Clin Infect Dis. 2014 Sep 1;59(5):651-7. doi: 10.1093/cid/ciu366. Epub 2014 May 19.


Characteristics of Escherichia coli sequence type 131 isolates that produce extended-spectrum β-lactamases: global distribution of the H30-Rx sublineage.

Peirano G, van der Bij AK, Freeman JL, Poirel L, Nordmann P, Costello M, Tchesnokova VL, Pitout JD.

Antimicrob Agents Chemother. 2014 Jul;58(7):3762-7. doi: 10.1128/AAC.02428-14. Epub 2014 Apr 21.


Multiplex PCR for identification of two capsular types in epidemic KPC-producing Klebsiella pneumoniae sequence type 258 strains.

Chen L, Chavda KD, Findlay J, Peirano G, Hopkins K, Pitout JD, Bonomo RA, Woodford N, DeLeo FR, Kreiswirth BN.

Antimicrob Agents Chemother. 2014 Jul;58(7):4196-9. doi: 10.1128/AAC.02673-14. Epub 2014 Apr 14.


Pilot testing of an out-of-country medical care questionnaire with screening and cost analysis of preemptive isolation for carbapenem-resistant Enterobacteriaceae in a large Canadian health region.

Rajapakse N, Vayalumkal J, Lam-Li D, Pearce C, Rees G, Kamhuka L, Peirano G, Pidhorney C, Ledgerwood D, Alfieri N, Hope K, Gregson D, Pitout J, Louie T, Conly J.

Infect Control Hosp Epidemiol. 2014 Apr;35(4):450-1. doi: 10.1086/675616. No abstract available.


Travel-related carbapenemase-producing Gram-negative bacteria in Alberta, Canada: the first 3 years.

Peirano G, Ahmed-Bentley J, Fuller J, Rubin JE, Pitout JD.

J Clin Microbiol. 2014 May;52(5):1575-81. doi: 10.1128/JCM.00162-14. Epub 2014 Mar 5.


Population-based surveillance for hypermucoviscosity Klebsiella pneumoniae causing community-acquired bacteremia in Calgary, Alberta.

Peirano G, Pitout JD, Laupland KB, Meatherall B, Gregson DB.

Can J Infect Dis Med Microbiol. 2013 Fall;24(3):e61-4.


Molecular epidemiology of Enterobacteriaceae that produce VIMs and IMPs from the SMART surveillance program.

Peirano G, Lascols C, Hackel M, Hoban DJ, Pitout JD.

Diagn Microbiol Infect Dis. 2014 Mar;78(3):277-81. doi: 10.1016/j.diagmicrobio.2013.11.024. Epub 2013 Dec 6.


Gram-negative bacteria that produce carbapenemases causing death attributed to recent foreign hospitalization.

Ahmed-Bentley J, Chandran AU, Joffe AM, French D, Peirano G, Pitout JD.

Antimicrob Agents Chemother. 2013 Jul;57(7):3085-91. doi: 10.1128/AAC.00297-13. Epub 2013 Apr 22.


Virulence potential and adherence properties of Escherichia coli that produce CTX-M and NDM β-lactamases.

Peirano G, Mulvey GL, Armstrong GD, Pitout JD.

J Med Microbiol. 2013 Apr;62(Pt 4):525-30. doi: 10.1099/jmm.0.048983-0. Epub 2013 Jan 14.


The characteristics of Klebsiella pneumoniae that produce KPC-2 imported from Greece.

Chan WW, Peirano G, Smyth DJ, Pitout JD.

Diagn Microbiol Infect Dis. 2013 Mar;75(3):317-9. doi: 10.1016/j.diagmicrobio.2012.12.003. Epub 2013 Jan 11.


Antimicrobial susceptibility and combination testing of invasive Stenotrophomonas maltophilia isolates.

Church D, Lloyd T, Peirano G, Pitout J.

Scand J Infect Dis. 2013 Apr;45(4):265-70. doi: 10.3109/00365548.2012.732240. Epub 2012 Oct 31.


Surveillance and molecular epidemiology of Klebsiella pneumoniae isolates that produce carbapenemases: first report of OXA-48-like enzymes in North America.

Lascols C, Peirano G, Hackel M, Laupland KB, Pitout JD.

Antimicrob Agents Chemother. 2013 Jan;57(1):130-6. doi: 10.1128/AAC.01686-12. Epub 2012 Oct 15.


Laboratory detection of Enterobacteriaceae that produce carbapenemases.

Doyle D, Peirano G, Lascols C, Lloyd T, Church DL, Pitout JD.

J Clin Microbiol. 2012 Dec;50(12):3877-80. doi: 10.1128/JCM.02117-12. Epub 2012 Sep 19.


Metallo-β-lactamase-producing Pseudomonas aeruginosa in the Netherlands: the nationwide emergence of a single sequence type.

Van der Bij AK, Van der Zwan D, Peirano G, Severin JA, Pitout JD, Van Westreenen M, Goessens WH; MBL-PA Surveillance Study Group.

Clin Microbiol Infect. 2012 Sep;18(9):E369-72. doi: 10.1111/j.1469-0691.2012.03969.x. Epub 2012 Jul 13.


Molecular methods for pathogen and microbial community detection and characterization: current and potential application in diagnostic microbiology.

Sibley CD, Peirano G, Church DL.

Infect Genet Evol. 2012 Apr;12(3):505-21. doi: 10.1016/j.meegid.2012.01.011. Epub 2012 Feb 9. Review.


Molecular epidemiology of extended-spectrum-β-lactamase-producing Klebsiella pneumoniae over a 10 year period in Calgary, Canada.

Peirano G, Sang JH, Pitondo-Silva A, Laupland KB, Pitout JD.

J Antimicrob Chemother. 2012 May;67(5):1114-20. doi: 10.1093/jac/dks026. Epub 2012 Feb 14.


The presence of genes encoding for different virulence factors in clonally related Escherichia coli that produce CTX-Ms.

Van der Bij AK, Peirano G, Pitondo-Silva A, Pitout JD.

Diagn Microbiol Infect Dis. 2012 Apr;72(4):297-302. doi: 10.1016/j.diagmicrobio.2011.12.011. Epub 2012 Feb 1.


Molecular epidemiology over an 11-year period (2000 to 2010) of extended-spectrum β-lactamase-producing Escherichia coli causing bacteremia in a centralized Canadian region.

Peirano G, van der Bij AK, Gregson DB, Pitout JD.

J Clin Microbiol. 2012 Feb;50(2):294-9. doi: 10.1128/JCM.06025-11. Epub 2011 Dec 7.


The characteristics of VIM-1-producing Klebsiella pneumoniae from South Africa.

Peirano G, Moolman J, Pitondo-Silva A, Pitout JD.

Scand J Infect Dis. 2012 Jan;44(1):74-8. doi: 10.3109/00365548.2011.614276. Epub 2011 Sep 28.


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