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Items: 1 to 50 of 60

1.

Neutrophils instruct homeostatic and pathological states in naive tissues.

Casanova-Acebes M, Nicolás-Ávila JA, Li JL, García-Silva S, Balachander A, Rubio-Ponce A, Weiss LA, Adrover JM, Burrows K, A-González N, Ballesteros I, Devi S, Quintana JA, Crainiciuc G, Leiva M, Gunzer M, Weber C, Nagasawa T, Soehnlein O, Merad M, Mortha A, Ng LG, Peinado H, Hidalgo A.

J Exp Med. 2018 Nov 5;215(11):2778-2795. doi: 10.1084/jem.20181468. Epub 2018 Oct 3.

PMID:
30282719
2.

Human prostasomes from normozoospermic and non-normozoospermic men show a differential protein expression pattern.

García-Rodríguez A, de la Casa M, Peinado H, Gosálvez J, Roy R.

Andrology. 2018 Jul;6(4):585-596. doi: 10.1111/andr.12496. Epub 2018 May 3.

PMID:
29726126
3.

Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation.

Zhang H, Freitas D, Kim HS, Fabijanic K, Li Z, Chen H, Mark MT, Molina H, Martin AB, Bojmar L, Fang J, Rampersaud S, Hoshino A, Matei I, Kenific CM, Nakajima M, Mutvei AP, Sansone P, Buehring W, Wang H, Jimenez JP, Cohen-Gould L, Paknejad N, Brendel M, Manova-Todorova K, Magalhães A, Ferreira JA, Osório H, Silva AM, Massey A, Cubillos-Ruiz JR, Galletti G, Giannakakou P, Cuervo AM, Blenis J, Schwartz R, Brady MS, Peinado H, Bromberg J, Matsui H, Reis CA, Lyden D.

Nat Cell Biol. 2018 Mar;20(3):332-343. doi: 10.1038/s41556-018-0040-4. Epub 2018 Feb 19.

4.

Evaluation of Endoglin (CD105) expression in pediatric rhabdomyosarcoma.

Di Paolo V, Russo I, Boldrini R, Ravà L, Pezzullo M, Benedetti MC, Galardi A, Colletti M, Rota R, Orlando D, Crocoli A, Peinado H, Milano GM, Di Giannatale A.

BMC Cancer. 2018 Jan 5;18(1):31. doi: 10.1186/s12885-017-3947-4.

5.

Lysyl oxidase-like 3 is required for melanoma cell survival by maintaining genomic stability.

Santamaría PG, Floristán A, Fontanals-Cirera B, Vázquez-Naharro A, Santos V, Morales S, Yuste L, Peinado H, García-Gómez A, Portillo F, Hernando E, Cano A.

Cell Death Differ. 2018 May;25(5):935-950. doi: 10.1038/s41418-017-0030-2. Epub 2017 Dec 11.

6.

The influence of tumour-derived extracellular vesicles on local and distal metastatic dissemination.

Nogués L, Benito-Martin A, Hergueta-Redondo M, Peinado H.

Mol Aspects Med. 2018 Apr;60:15-26. doi: 10.1016/j.mam.2017.11.012. Epub 2017 Dec 6. Review.

PMID:
29196097
7.

Tumour-adipose tissue crosstalk: fuelling tumour metastasis by extracellular vesicles.

Robado de Lope L, Alcíbar OL, Amor López A, Hergueta-Redondo M, Peinado H.

Philos Trans R Soc Lond B Biol Sci. 2018 Jan 5;373(1737). pii: 20160485. doi: 10.1098/rstb.2016.0485. Review.

PMID:
29158314
8.

Neonatal sepsis secondary to chorioamnionitis by Actinomyces neuii in a 25 weeks pregnant woman.

Giron de Velasco-Sada P, Peinado H, Romero-Gómez MP.

Med Clin (Barc). 2018 May 23;150(10):407-408. doi: 10.1016/j.medcli.2017.10.007. Epub 2017 Nov 14. English, Spanish. No abstract available.

PMID:
29150122
9.

Proteomic Analysis of Neuroblastoma-Derived Exosomes: New Insights into a Metastatic Signature.

Colletti M, Petretto A, Galardi A, Di Paolo V, Tomao L, Lavarello C, Inglese E, Bruschi M, Lopez AA, Pascucci L, Geoerger B, Peinado H, Locatelli F, Di Giannatale A.

Proteomics. 2017 Dec;17(23-24). doi: 10.1002/pmic.201600430. Epub 2017 Sep 12.

PMID:
28722341
10.

A novel community driven software for functional enrichment analysis of extracellular vesicles data.

Pathan M, Keerthikumar S, Chisanga D, Alessandro R, Ang CS, Askenase P, Batagov AO, Benito-Martin A, Camussi G, Clayton A, Collino F, Di Vizio D, Falcon-Perez JM, Fonseca P, Fonseka P, Fontana S, Gho YS, Hendrix A, Hoen EN, Iraci N, Kastaniegaard K, Kislinger T, Kowal J, Kurochkin IV, Leonardi T, Liang Y, Llorente A, Lunavat TR, Maji S, Monteleone F, Øverbye A, Panaretakis T, Patel T, Peinado H, Pluchino S, Principe S, Ronquist G, Royo F, Sahoo S, Spinelli C, Stensballe A, Théry C, van Herwijnen MJC, Wauben M, Welton JL, Zhao K, Mathivanan S.

J Extracell Vesicles. 2017 May 26;6(1):1321455. doi: 10.1080/20013078.2017.1321455. eCollection 2017.

11.

Phagocytosis imprints heterogeneity in tissue-resident macrophages.

A-Gonzalez N, Quintana JA, García-Silva S, Mazariegos M, González de la Aleja A, Nicolás-Ávila JA, Walter W, Adrover JM, Crainiciuc G, Kuchroo VK, Rothlin CV, Peinado H, Castrillo A, Ricote M, Hidalgo A.

J Exp Med. 2017 May 1;214(5):1281-1296. doi: 10.1084/jem.20161375. Epub 2017 Apr 21.

12.

A proangiogenic signaling axis in myeloid cells promotes malignant progression of glioma.

Huang Y, Rajappa P, Hu W, Hoffman C, Cisse B, Kim JH, Gorge E, Yanowitch R, Cope W, Vartanian E, Xu R, Zhang T, Pisapia D, Xiang J, Huse J, Matei I, Peinado H, Bromberg J, Holland E, Ding BS, Rafii S, Lyden D, Greenfield J.

J Clin Invest. 2017 May 1;127(5):1826-1838. doi: 10.1172/JCI86443. Epub 2017 Apr 10.

13.

Pre-metastatic niches: organ-specific homes for metastases.

Peinado H, Zhang H, Matei IR, Costa-Silva B, Hoshino A, Rodrigues G, Psaila B, Kaplan RN, Bromberg JF, Kang Y, Bissell MJ, Cox TR, Giaccia AJ, Erler JT, Hiratsuka S, Ghajar CM, Lyden D.

Nat Rev Cancer. 2017 May;17(5):302-317. doi: 10.1038/nrc.2017.6. Epub 2017 Mar 17. Review.

14.

Extracellular Vesicles in Cancer: Cell-to-Cell Mediators of Metastasis.

Becker A, Thakur BK, Weiss JM, Kim HS, Peinado H, Lyden D.

Cancer Cell. 2016 Dec 12;30(6):836-848. doi: 10.1016/j.ccell.2016.10.009. Review.

15.

Corrigendum: Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET.

Peinado H, Alecˇković M, Lavotshkin S, Matei I, Costa-Silva B, Moreno-Bueno G, Hergueta-Redondo M, Williams C, García-Santos G, Ghajar CM, Nitadori-Hoshino A, Hoffman C, Badal K, Garcia BA, Callahan MK, Yuan J, Martins VR, Skog J, Kaplan RN, Brady MS, Wolchok JD, Chapman PB, Kang Y, Bromberg J, Lyden D.

Nat Med. 2016 Dec 6;22(12):1502. doi: 10.1038/nm1216-1502b. No abstract available.

PMID:
27923027
16.

Melanosomes foster a tumour niche by activating CAFs.

García-Silva S, Peinado H.

Nat Cell Biol. 2016 Aug 30;18(9):911-3. doi: 10.1038/ncb3404.

PMID:
27571736
17.

Vesicle-MaNiA: extracellular vesicles in liquid biopsy and cancer.

Torrano V, Royo F, Peinado H, Loizaga-Iriarte A, Unda M, Falcón-Perez JM, Carracedo A.

Curr Opin Pharmacol. 2016 Aug;29:47-53. doi: 10.1016/j.coph.2016.06.003. Epub 2016 Jun 28. Review.

18.

Mast cells and exosomes in hyperoxia-induced neonatal lung disease.

Veerappan A, Thompson M, Savage AR, Silverman ML, Chan WS, Sung B, Summers B, Montelione KC, Benedict P, Groh B, Vicencio AG, Peinado H, Worgall S, Silver RB.

Am J Physiol Lung Cell Mol Physiol. 2016 Jun 1;310(11):L1218-32. doi: 10.1152/ajplung.00299.2015. Epub 2016 Apr 29.

19.

Characterization of Induced Pluripotent Stem Cell Microvesicle Genesis, Morphology and Pluripotent Content.

Zhou J, Ghoroghi S, Benito-Martin A, Wu H, Unachukwu UJ, Einbond LS, Guariglia S, Peinado H, Redenti S.

Sci Rep. 2016 Jan 22;6:19743. doi: 10.1038/srep19743.

20.

Tumour exosome integrins determine organotropic metastasis.

Hoshino A, Costa-Silva B, Shen TL, Rodrigues G, Hashimoto A, Tesic Mark M, Molina H, Kohsaka S, Di Giannatale A, Ceder S, Singh S, Williams C, Soplop N, Uryu K, Pharmer L, King T, Bojmar L, Davies AE, Ararso Y, Zhang T, Zhang H, Hernandez J, Weiss JM, Dumont-Cole VD, Kramer K, Wexler LH, Narendran A, Schwartz GK, Healey JH, Sandstrom P, Labori KJ, Kure EH, Grandgenett PM, Hollingsworth MA, de Sousa M, Kaur S, Jain M, Mallya K, Batra SK, Jarnagin WR, Brady MS, Fodstad O, Muller V, Pantel K, Minn AJ, Bissell MJ, Garcia BA, Kang Y, Rajasekhar VK, Ghajar CM, Matei I, Peinado H, Bromberg J, Lyden D.

Nature. 2015 Nov 19;527(7578):329-35. doi: 10.1038/nature15756. Epub 2015 Oct 28.

21.

FunRich proteomics software analysis, let the fun begin!

Benito-Martin A, Peinado H.

Proteomics. 2015 Aug;15(15):2555-6. doi: 10.1002/pmic.201500260.

PMID:
26149235
22.

Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver.

Costa-Silva B, Aiello NM, Ocean AJ, Singh S, Zhang H, Thakur BK, Becker A, Hoshino A, Mark MT, Molina H, Xiang J, Zhang T, Theilen TM, García-Santos G, Williams C, Ararso Y, Huang Y, Rodrigues G, Shen TL, Labori KJ, Lothe IM, Kure EH, Hernandez J, Doussot A, Ebbesen SH, Grandgenett PM, Hollingsworth MA, Jain M, Mallya K, Batra SK, Jarnagin WR, Schwartz RE, Matei I, Peinado H, Stanger BZ, Bromberg J, Lyden D.

Nat Cell Biol. 2015 Jun;17(6):816-26. doi: 10.1038/ncb3169. Epub 2015 May 18.

23.

Id1 suppresses anti-tumour immune responses and promotes tumour progression by impairing myeloid cell maturation.

Papaspyridonos M, Matei I, Huang Y, do Rosario Andre M, Brazier-Mitouart H, Waite JC, Chan AS, Kalter J, Ramos I, Wu Q, Williams C, Wolchok JD, Chapman PB, Peinado H, Anandasabapathy N, Ocean AJ, Kaplan RN, Greenfield JP, Bromberg J, Skokos D, Lyden D.

Nat Commun. 2015 Apr 29;6:6840. doi: 10.1038/ncomms7840.

24.

Loss of Snail2 favors skin tumor progression by promoting the recruitment of myeloid progenitors.

Villarejo A, Molina-Ortiz P, Montenegro Y, Moreno-Bueno G, Morales S, Santos V, Gridley T, Pérez-Moreno MA, Peinado H, Portillo F, Calés C, Cano A.

Carcinogenesis. 2015 May;36(5):585-97. doi: 10.1093/carcin/bgv021. Epub 2015 Mar 16.

25.

The new deal: a potential role for secreted vesicles in innate immunity and tumor progression.

Benito-Martin A, Di Giannatale A, Ceder S, Peinado H.

Front Immunol. 2015 Feb 24;6:66. doi: 10.3389/fimmu.2015.00066. eCollection 2015. Review.

26.

Double-stranded DNA in exosomes: a novel biomarker in cancer detection.

Thakur BK, Zhang H, Becker A, Matei I, Huang Y, Costa-Silva B, Zheng Y, Hoshino A, Brazier H, Xiang J, Williams C, Rodriguez-Barrueco R, Silva JM, Zhang W, Hearn S, Elemento O, Paknejad N, Manova-Todorova K, Welte K, Bromberg J, Peinado H, Lyden D.

Cell Res. 2014 Jun;24(6):766-9. doi: 10.1038/cr.2014.44. Epub 2014 Apr 8. No abstract available.

27.

Gasdermin-B promotes invasion and metastasis in breast cancer cells.

Hergueta-Redondo M, Sarrió D, Molina-Crespo Á, Megias D, Mota A, Rojo-Sebastian A, García-Sanz P, Morales S, Abril S, Cano A, Peinado H, Moreno-Bueno G.

PLoS One. 2014 Mar 27;9(3):e90099. doi: 10.1371/journal.pone.0090099. eCollection 2014.

28.

Lysyl oxidase-like 2 (LOXL2) and E47 EMT factor: novel partners in E-cadherin repression and early metastasis colonization.

Canesin G, Cuevas EP, Santos V, López-Menéndez C, Moreno-Bueno G, Huang Y, Csiszar K, Portillo F, Peinado H, Lyden D, Cano A.

Oncogene. 2015 Feb 19;34(8):951-64. doi: 10.1038/onc.2014.23. Epub 2014 Mar 17.

PMID:
24632622
29.

Macromolecular crowding meets tissue engineering by self-assembly: a paradigm shift in regenerative medicine.

Satyam A, Kumar P, Fan X, Gorelov A, Rochev Y, Joshi L, Peinado H, Lyden D, Thomas B, Rodriguez B, Raghunath M, Pandit A, Zeugolis D.

Adv Mater. 2014 May 21;26(19):3024-34. doi: 10.1002/adma.201304428. Epub 2014 Feb 6.

PMID:
24505025
30.

The perivascular niche regulates breast tumour dormancy.

Ghajar CM, Peinado H, Mori H, Matei IR, Evason KJ, Brazier H, Almeida D, Koller A, Hajjar KA, Stainier DY, Chen EI, Lyden D, Bissell MJ.

Nat Cell Biol. 2013 Jul;15(7):807-17. doi: 10.1038/ncb2767. Epub 2013 Jun 2.

31.

Mutation of SIMPLE in Charcot-Marie-Tooth 1C alters production of exosomes.

Zhu H, Guariglia S, Yu RY, Li W, Brancho D, Peinado H, Lyden D, Salzer J, Bennett C, Chow CW.

Mol Biol Cell. 2013 Jun;24(11):1619-37, S1-3. doi: 10.1091/mbc.E12-07-0544. Epub 2013 Apr 10.

32.

E47 and Id1 interplay in epithelial-mesenchymal transition.

Cubillo E, Diaz-Lopez A, Cuevas EP, Moreno-Bueno G, Peinado H, Montes A, Santos V, Portillo F, Cano A.

PLoS One. 2013;8(3):e59948. doi: 10.1371/journal.pone.0059948. Epub 2013 Mar 26.

33.

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET.

Peinado H, Alečković M, Lavotshkin S, Matei I, Costa-Silva B, Moreno-Bueno G, Hergueta-Redondo M, Williams C, García-Santos G, Ghajar C, Nitadori-Hoshino A, Hoffman C, Badal K, Garcia BA, Callahan MK, Yuan J, Martins VR, Skog J, Kaplan RN, Brady MS, Wolchok JD, Chapman PB, Kang Y, Bromberg J, Lyden D.

Nat Med. 2012 Jun;18(6):883-91. doi: 10.1038/nm.2753. Erratum in: Nat Med. 2016 Dec 6;22(12 ):1502.

34.

International Society for Extracellular Vesicles: first annual meeting, April 17-21, 2012: ISEV-2012.

Araldi E, Krämer-Albers EM, Hoen EN, Peinado H, Psonka-Antonczyk KM, Rao P, van Niel G, Yáñez-Mó M, Nazarenko I.

J Extracell Vesicles. 2012 Dec 28;1:19995. doi: 10.3402/jev.v1i0.19995. eCollection 2012.

35.

Regulation of SNAIL1 and E-cadherin function by DNMT1 in a DNA methylation-independent context.

Espada J, Peinado H, Lopez-Serra L, Setién F, Lopez-Serra P, Portela A, Renart J, Carrasco E, Calvo M, Juarranz A, Cano A, Esteller M.

Nucleic Acids Res. 2011 Nov;39(21):9194-205. doi: 10.1093/nar/gkr658. Epub 2011 Aug 16.

36.

Lysyl oxidase-like 2 (LOXL2), a new regulator of cell polarity required for metastatic dissemination of basal-like breast carcinomas.

Moreno-Bueno G, Salvador F, Martín A, Floristán A, Cuevas EP, Santos V, Montes A, Morales S, Castilla MA, Rojo-Sebastián A, Martínez A, Hardisson D, Csiszar K, Portillo F, Peinado H, Palacios J, Cano A.

EMBO Mol Med. 2011 Sep;3(9):528-44. doi: 10.1002/emmm.201100156. Epub 2011 Jul 6.

37.

The secreted factors responsible for pre-metastatic niche formation: old sayings and new thoughts.

Peinado H, Lavotshkin S, Lyden D.

Semin Cancer Biol. 2011 Apr;21(2):139-46. doi: 10.1016/j.semcancer.2011.01.002. Epub 2011 Jan 18. Review.

PMID:
21251983
38.

The morphological and molecular features of the epithelial-to-mesenchymal transition.

Moreno-Bueno G, Peinado H, Molina P, Olmeda D, Cubillo E, Santos V, Palacios J, Portillo F, Cano A.

Nat Protoc. 2009;4(11):1591-613. doi: 10.1038/nprot.2009.152. Epub 2009 Oct 15.

PMID:
19834475
39.

PAI-1 and functional blockade of SNAI1 in breast cancer cell migration.

Fabre-Guillevin E, Malo M, Cartier-Michaud A, Peinado H, Moreno-Bueno G, Vallée B, Lawrence DA, Palacios J, Cano A, Barlovatz-Meimon G, Charrière-Bertrand C.

Breast Cancer Res. 2008;10(6):R100. doi: 10.1186/bcr2203. Epub 2008 Dec 3.

40.

Inflammation joins the "niche".

Peinado H, Rafii S, Lyden D.

Cancer Cell. 2008 Nov 4;14(5):347-9. doi: 10.1016/j.ccr.2008.10.012.

41.

HMGA2 and Smads co-regulate SNAIL1 expression during induction of epithelial-to-mesenchymal transition.

Thuault S, Tan EJ, Peinado H, Cano A, Heldin CH, Moustakas A.

J Biol Chem. 2008 Nov 28;283(48):33437-46. doi: 10.1074/jbc.M802016200. Epub 2008 Oct 1.

42.

Lysyl oxidase-like 2 as a new poor prognosis marker of squamous cell carcinomas.

Peinado H, Moreno-Bueno G, Hardisson D, Pérez-Gómez E, Santos V, Mendiola M, de Diego JI, Nistal M, Quintanilla M, Portillo F, Cano A.

Cancer Res. 2008 Jun 15;68(12):4541-50. doi: 10.1158/0008-5472.CAN-07-6345.

43.

Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling.

Malanchi I, Peinado H, Kassen D, Hussenet T, Metzger D, Chambon P, Huber M, Hohl D, Cano A, Birchmeier W, Huelsken J.

Nature. 2008 Apr 3;452(7187):650-3. doi: 10.1038/nature06835.

PMID:
18385740
44.

A hypoxic twist in metastasis.

Peinado H, Cano A.

Nat Cell Biol. 2008 Mar;10(3):253-4. doi: 10.1038/ncb0308-253. No abstract available.

PMID:
18311179
45.

Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?

Peinado H, Olmeda D, Cano A.

Nat Rev Cancer. 2007 Jun;7(6):415-28. Epub 2007 May 17. Review.

PMID:
17508028
46.

New potential therapeutic targets to combat epithelial tumor invasion.

Peinado H, Cano A.

Clin Transl Oncol. 2006 Dec;8(12):851-7. Review.

PMID:
17169758
47.

Snail silencing effectively suppresses tumour growth and invasiveness.

Olmeda D, Jordá M, Peinado H, Fabra A, Cano A.

Oncogene. 2007 Mar 22;26(13):1862-74. Epub 2006 Oct 9.

PMID:
17043660
48.

Mechanisms of endothelial cell protection by blockade of the JAK2 pathway.

Neria F, Caramelo C, Peinado H, González-Pacheco FR, Deudero JJ, de Solis AJ, Fernández-Sánchez R, Peñate S, Cano A, Castilla MA.

Am J Physiol Cell Physiol. 2007 Mar;292(3):C1123-31. Epub 2006 Oct 11.

49.

Genetic profiling of epithelial cells expressing E-cadherin repressors reveals a distinct role for Snail, Slug, and E47 factors in epithelial-mesenchymal transition.

Moreno-Bueno G, Cubillo E, Sarrió D, Peinado H, Rodríguez-Pinilla SM, Villa S, Bolós V, Jordá M, Fabra A, Portillo F, Palacios J, Cano A.

Cancer Res. 2006 Oct 1;66(19):9543-56.

50.

Switching on-off Snail: LOXL2 versus GSK3beta.

Peinado H, Portillo F, Cano A.

Cell Cycle. 2005 Dec;4(12):1749-52. Epub 2005 Dec 5.

PMID:
16294032

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