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Items: 20

1.

AZD7624, an Inhaled p38 Inhibitor, Demonstrates Local Lung Inhibition of LPS-Induced TNFα with Minimal Systemic Exposure.

Pehrson R, Hegelund-Myrbäck T, Cunoosamy D, Asimus S, Jansson P, Patel N, Borde A, Lundin S.

J Pharmacol Exp Ther. 2018 Jun;365(3):567-572. doi: 10.1124/jpet.117.246132. Epub 2018 Mar 16.

PMID:
29549158
2.

An S-warfarin and AZD1981 interaction: in vitro and clinical pilot data suggest the N-deacetylated amino acid metabolite as the primary perpetrator.

Grime K, Pehrson R, Nordell P, Gillen M, Kühn W, Mant T, Brännström M, Svanberg P, Jones B, Brealey C.

Br J Clin Pharmacol. 2017 Feb;83(2):381-392. doi: 10.1111/bcp.13102. Epub 2016 Oct 13.

3.

Modeling and design of challenge tests: Inflammatory and metabolic biomarker study examples.

Gabrielsson J, Hjorth S, Vogg B, Harlfinger S, Gutierrez PM, Peletier L, Pehrson R, Davidsson P.

Eur J Pharm Sci. 2015 Jan 25;67:144-159. doi: 10.1016/j.ejps.2014.11.006. Epub 2014 Nov 28.

PMID:
25435491
4.

Pharmacokinetic-pharmacodynamic modeling of QRS-prolongation by flecainide: heart rate-dependent effects during sinus rhythm in conscious telemetered dogs.

Sällström J, Al-Saffar A, Pehrson R.

J Pharmacol Toxicol Methods. 2014 Jan-Feb;69(1):24-9. doi: 10.1016/j.vascn.2013.10.001. Epub 2013 Oct 16.

PMID:
24140388
5.

The impact of the site of blood sampling on pharmacokinetic parameters following sublingual dosing to dogs.

Sohlberg E, Halldin MM, Annas A, Königsson K, Jansson B, Pehrson R, Borg N.

J Pharmacol Toxicol Methods. 2013 Jan-Feb;67(1):1-4. doi: 10.1016/j.vascn.2012.10.004. Epub 2012 Nov 5.

PMID:
23138149
6.

Exploration of human, rat, and rabbit embryonic cardiomyocytes suggests K-channel block as a common teratogenic mechanism.

Danielsson C, Brask J, Sköld AC, Genead R, Andersson A, Andersson U, Stockling K, Pehrson R, Grinnemo KH, Salari S, Hellmold H, Danielsson B, Sylvén C, Elinder F.

Cardiovasc Res. 2013 Jan 1;97(1):23-32. doi: 10.1093/cvr/cvs296. Epub 2012 Sep 20.

PMID:
22997158
7.

Extending half-life by indirect targeting of the neonatal Fc receptor (FcRn) using a minimal albumin binding domain.

Andersen JT, Pehrson R, Tolmachev V, Daba MB, Abrahmsén L, Ekblad C.

J Biol Chem. 2011 Feb 18;286(7):5234-41. doi: 10.1074/jbc.M110.164848. Epub 2010 Dec 7.

8.

Iodixanol 320 results in better renal tolerance and radiodensity than do gadolinium-based contrast media: arteriography in ischemic porcine kidneys.

Elmståhl B, Nyman U, Leander P, Golman K, Chai CM, Grant D, Doughty R, Pehrson R, Björk J, Almén T.

Radiology. 2008 Apr;247(1):88-97. doi: 10.1148/radiol.2471070420. Epub 2008 Feb 21.

PMID:
18292474
9.

Radionuclide therapy of HER2-positive microxenografts using a 177Lu-labeled HER2-specific Affibody molecule.

Tolmachev V, Orlova A, Pehrson R, Galli J, Baastrup B, Andersson K, Sandström M, Rosik D, Carlsson J, Lundqvist H, Wennborg A, Nilsson FY.

Cancer Res. 2007 Mar 15;67(6):2773-82.

10.

Synthetic affibody molecules: a novel class of affinity ligands for molecular imaging of HER2-expressing malignant tumors.

Orlova A, Tolmachev V, Pehrson R, Lindborg M, Tran T, Sandström M, Nilsson FY, Wennborg A, Abrahmsén L, Feldwisch J.

Cancer Res. 2007 Mar 1;67(5):2178-86.

11.

Metabolic imaging by hyperpolarized 13C magnetic resonance imaging for in vivo tumor diagnosis.

Golman K, Zandt RI, Lerche M, Pehrson R, Ardenkjaer-Larsen JH.

Cancer Res. 2006 Nov 15;66(22):10855-60.

12.
13.

Effects of tramadol on rat detrusor overactivity induced by experimental cerebral infarction.

Pehrson R, Stenman E, Andersson KE.

Eur Urol. 2003 Oct;44(4):495-9.

PMID:
14499688
14.

Actions of tramadol on micturition in awake, freely moving rats.

Pandita RK, Pehrson R, Christoph T, Friderichs E, Andersson KE.

Br J Pharmacol. 2003 Jun;139(4):741-8.

15.

Tramadol inhibits rat detrusor overactivity caused by dopamine receptor stimulation.

Pehrson R, Andersson KE.

J Urol. 2003 Jul;170(1):272-5.

PMID:
12796703
16.

Effects of NAD-299, a new, highly selective 5-HT1A receptor antagonist, on bladder function in rats.

Pehrson R, Ojteg G, Ishizuka O, Andersson KE.

Naunyn Schmiedebergs Arch Pharmacol. 2002 Dec;366(6):528-36. Epub 2002 Oct 17.

PMID:
12444493
17.
18.
19.

Role of supraspinal serotonin receptors for micturition in normal conscious rats.

Ishizuka O, Gu B, Igawa Y, Nishizawa O, Pehrson R, Andersson KE.

Neurourol Urodyn. 2002;21(3):225-30.

PMID:
11948716
20.

Survival of Lactobacillus helveticus entrapped in Ca-alginate in relation to water content, storage and rehydration.

Selmer-Olsen E, Sørhaug T, Birkeland SE, Pehrson R.

J Ind Microbiol Biotechnol. 1999 Aug;23(2):79-85.

PMID:
10510483

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