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Items: 33

1.

A novel assay to screen siRNA libraries identifies protein kinases required for chromosome transmission.

Liskovykh M, Goncharov NV, Petrov N, Aksenova V, Pegoraro G, Ozbun LL, Reinhold WC, Varma S, Dasso M, Kumeiko V, Masumoto H, Earnshaw WC, Larionov V, Kouprina N.

Genome Res. 2019 Oct;29(10):1719-1732. doi: 10.1101/gr.254276.119. Epub 2019 Sep 12.

2.

Transcriptional Bursting and Co-bursting Regulation by Steroid Hormone Release Pattern and Transcription Factor Mobility.

Stavreva DA, Garcia DA, Fettweis G, Gudla PR, Zaki GF, Soni V, McGowan A, Williams G, Huynh A, Palangat M, Schiltz RL, Johnson TA, Presman DM, Ferguson ML, Pegoraro G, Upadhyaya A, Hager GL.

Mol Cell. 2019 Sep 19;75(6):1161-1177.e11. doi: 10.1016/j.molcel.2019.06.042. Epub 2019 Aug 14.

PMID:
31421980
3.

The nucleoporin ELYS regulates nuclear size by controlling NPC number and nuclear import capacity.

Jevtić P, Schibler AC, Wesley CC, Pegoraro G, Misteli T, Levy DL.

EMBO Rep. 2019 Jun;20(6). pii: e47283. doi: 10.15252/embr.201847283. Epub 2019 May 13.

PMID:
31085625
4.

Extensive Heterogeneity and Intrinsic Variation in Spatial Genome Organization.

Finn EH, Pegoraro G, Brandão HB, Valton AL, Oomen ME, Dekker J, Mirny L, Misteli T.

Cell. 2019 Mar 7;176(6):1502-1515.e10. doi: 10.1016/j.cell.2019.01.020. Epub 2019 Feb 21.

PMID:
30799036
5.

Blank spots on the map: some current questions on nuclear organization and genome architecture.

Adriaens C, Serebryannyy LA, Feric M, Schibler A, Meaburn KJ, Kubben N, Trzaskoma P, Shachar S, Vidak S, Finn EH, Sood V, Pegoraro G, Misteli T.

Histochem Cell Biol. 2018 Dec;150(6):579-592. doi: 10.1007/s00418-018-1726-1. Epub 2018 Sep 20. Review.

6.

Effects of human sex chromosome dosage on spatial chromosome organization.

Jowhar Z, Shachar S, Gudla PR, Wangsa D, Torres E, Russ JL, Pegoraro G, Ried T, Raznahan A, Misteli T.

Mol Biol Cell. 2018 Oct 1;29(20):2458-2469. doi: 10.1091/mbc.E18-06-0359. Epub 2018 Aug 9.

7.

HiCTMap: Detection and analysis of chromosome territory structure and position by high-throughput imaging.

Jowhar Z, Gudla PR, Shachar S, Wangsa D, Russ JL, Pegoraro G, Ried T, Raznahan A, Misteli T.

Methods. 2018 Jun 1;142:30-38. doi: 10.1016/j.ymeth.2018.01.013. Epub 2018 Feb 10.

8.

SpotLearn: Convolutional Neural Network for Detection of Fluorescence In Situ Hybridization (FISH) Signals in High-Throughput Imaging Approaches.

Gudla PR, Nakayama K, Pegoraro G, Misteli T.

Cold Spring Harb Symp Quant Biol. 2017;82:57-70. doi: 10.1101/sqb.2017.82.033761. Epub 2017 Nov 28.

9.

High-Throughput Imaging for the Discovery of Cellular Mechanisms of Disease.

Pegoraro G, Misteli T.

Trends Genet. 2017 Sep;33(9):604-615. doi: 10.1016/j.tig.2017.06.005. Epub 2017 Jul 18. Review.

10.

HiHiMap: single-cell quantitation of histones and histone posttranslational modifications across the cell cycle by high-throughput imaging.

Zane L, Chapus F, Pegoraro G, Misteli T.

Mol Biol Cell. 2017 Aug 15;28(17):2290-2302. doi: 10.1091/mbc.E16-12-0870. Epub 2017 Jun 14.

11.

Comparative analysis of 2D and 3D distance measurements to study spatial genome organization.

Finn EH, Pegoraro G, Shachar S, Misteli T.

Methods. 2017 Jul 1;123:47-55. doi: 10.1016/j.ymeth.2017.01.007. Epub 2017 Feb 5.

12.

Novel cell-based assay for detection of thyroid receptor beta-interacting environmental contaminants.

Stavreva DA, Varticovski L, Levkova L, George AA, Davis L, Pegoraro G, Blazer V, Iwanowicz L, Hager GL.

Toxicology. 2016 Aug 10;368-369:69-79. doi: 10.1016/j.tox.2016.08.012. Epub 2016 Aug 12.

13.

siRNA Screen Identifies Trafficking Host Factors that Modulate Alphavirus Infection.

Radoshitzky SR, Pegoraro G, Chī XO, D Ng L, Chiang CY, Jozwick L, Clester JC, Cooper CL, Courier D, Langan DP, Underwood K, Kuehl KA, Sun MG, Caì Y, Yú SQ, Burk R, Zamani R, Kota K, Kuhn JH, Bavari S.

PLoS Pathog. 2016 Mar 31;12(3):e1005466. doi: 10.1371/journal.ppat.1005466. eCollection 2016 Mar.

14.

Cajal bodies are linked to genome conformation.

Wang Q, Sawyer IA, Sung MH, Sturgill D, Shevtsov SP, Pegoraro G, Hakim O, Baek S, Hager GL, Dundr M.

Nat Commun. 2016 Mar 21;7:10966. doi: 10.1038/ncomms10966.

15.

High-throughput Imaging as a versatile and unbiased discovery tool.

Pegoraro G, Misteli T.

Methods. 2016 Mar 1;96:1-2. doi: 10.1016/j.ymeth.2016.01.003. Epub 2016 Jan 13. No abstract available.

16.

3D Chromosome Regulatory Landscape of Human Pluripotent Cells.

Ji X, Dadon DB, Powell BE, Fan ZP, Borges-Rivera D, Shachar S, Weintraub AS, Hnisz D, Pegoraro G, Lee TI, Misteli T, Jaenisch R, Young RA.

Cell Stem Cell. 2016 Feb 4;18(2):262-75. doi: 10.1016/j.stem.2015.11.007. Epub 2015 Dec 10.

17.

HIPMap: A High-Throughput Imaging Method for Mapping Spatial Gene Positions.

Shachar S, Pegoraro G, Misteli T.

Cold Spring Harb Symp Quant Biol. 2015;80:73-81. doi: 10.1101/sqb.2015.80.027417. Epub 2015 Oct 15. Review.

18.

Quantitative detection of rare interphase chromosome breaks and translocations by high-throughput imaging.

Burman B, Misteli T, Pegoraro G.

Genome Biol. 2015 Aug 3;16:146. doi: 10.1186/s13059-015-0718-x.

19.

Identification of Gene Positioning Factors Using High-Throughput Imaging Mapping.

Shachar S, Voss TC, Pegoraro G, Sciascia N, Misteli T.

Cell. 2015 Aug 13;162(4):911-23. doi: 10.1016/j.cell.2015.07.035.

20.

Histone modifications predispose genome regions to breakage and translocation.

Burman B, Zhang ZZ, Pegoraro G, Lieb JD, Misteli T.

Genes Dev. 2015 Jul 1;29(13):1393-402. doi: 10.1101/gad.262170.115. Epub 2015 Jun 23.

21.

Ectopic expression of RNF168 and 53BP1 increases mutagenic but not physiological non-homologous end joining.

Zong D, Callén E, Pegoraro G, Lukas C, Lukas J, Nussenzweig A.

Nucleic Acids Res. 2015 May 26;43(10):4950-61. doi: 10.1093/nar/gkv336. Epub 2015 Apr 27.

22.

Cell cycle staging of individual cells by fluorescence microscopy.

Roukos V, Pegoraro G, Voss TC, Misteli T.

Nat Protoc. 2015 Feb;10(2):334-48. doi: 10.1038/nprot.2015.016. Epub 2015 Jan 29.

23.

A high-content imaging assay for the quantification of the Burkholderia pseudomallei induced multinucleated giant cell (MNGC) phenotype in murine macrophages.

Pegoraro G, Eaton BP, Ulrich RL, Lane DJ, Ojeda JF, Bavari S, DeShazer D, Panchal RG.

BMC Microbiol. 2014 Apr 22;14:98. doi: 10.1186/1471-2180-14-98.

24.

Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430.

Warren TK, Wells J, Panchal RG, Stuthman KS, Garza NL, Van Tongeren SA, Dong L, Retterer CJ, Eaton BP, Pegoraro G, Honnold S, Bantia S, Kotian P, Chen X, Taubenheim BR, Welch LS, Minning DM, Babu YS, Sheridan WP, Bavari S.

Nature. 2014 Apr 17;508(7496):402-5. doi: 10.1038/nature13027. Epub 2014 Mar 2.

PMID:
24590073
25.

Crimean-Congo hemorrhagic fever virus utilizes a clathrin- and early endosome-dependent entry pathway.

Garrison AR, Radoshitzky SR, Kota KP, Pegoraro G, Ruthel G, Kuhn JH, Altamura LA, Kwilas SA, Bavari S, Haucke V, Schmaljohn CS.

Virology. 2013 Sep;444(1-2):45-54. doi: 10.1016/j.virol.2013.05.030. Epub 2013 Jun 19.

26.

Integrating high-content imaging and chemical genetics to probe host cellular pathways critical for Yersinia pestis infection.

Kota KP, Eaton B, Lane D, Ulrich M, Ulrich R, Peyser BD, Robinson CG, Jaissle JG, Pegoraro G, Bavari S, Panchal RG.

PLoS One. 2013;8(1):e55167. doi: 10.1371/journal.pone.0055167. Epub 2013 Jan 30.

27.

Shedding light on filovirus infection with high-content imaging.

Pegoraro G, Bavari S, Panchal RG.

Viruses. 2012 Aug;4(8):1354-71. doi: 10.3390/v4081354. Epub 2012 Aug 23. Review.

28.

Identification of mammalian protein quality control factors by high-throughput cellular imaging.

Pegoraro G, Voss TC, Martin SE, Tuzmen P, Guha R, Misteli T.

PLoS One. 2012;7(2):e31684. doi: 10.1371/journal.pone.0031684. Epub 2012 Feb 20.

29.

The central role of chromatin maintenance in aging.

Pegoraro G, Misteli T.

Aging (Albany NY). 2009 Dec 9;1(12):1017-22.

30.

Ageing-related chromatin defects through loss of the NURD complex.

Pegoraro G, Kubben N, Wickert U, Göhler H, Hoffmann K, Misteli T.

Nat Cell Biol. 2009 Oct;11(10):1261-7. doi: 10.1038/ncb1971. Epub 2009 Sep 6.

31.

Regulation of adeno-associated virus DNA replication by the cellular TAF-I/set complex.

Pegoraro G, Marcello A, Myers MP, Giacca M.

J Virol. 2006 Jul;80(14):6855-64.

32.

Nuclear organization and the control of HIV-1 transcription.

Marcello A, Lusic M, Pegoraro G, Pellegrini V, Beltram F, Giacca M.

Gene. 2004 Feb 4;326:1-11. Review.

PMID:
14729258
33.

Recruitment of human cyclin T1 to nuclear bodies through direct interaction with the PML protein.

Marcello A, Ferrari A, Pellegrini V, Pegoraro G, Lusic M, Beltram F, Giacca M.

EMBO J. 2003 May 1;22(9):2156-66.

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