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Aflibercept Plus FOLFIRI for Second-line Treatment of Metastatic Colorectal Cancer: Observations from the Global Aflibercept Safety and Health-Related Quality-of-Life Program (ASQoP).

Riechelmann RP, Srimuninnimit V, Bordonaro R, Kavan P, Di Bartolomeo M, Maiello E, Cicin I, García-Alfonso P, Chau I, Fedyanin MY, Martos CF, Ter-Ovanesov M, Peeters M, Ko YJ, Yalcin S, Karthaus M, Aparicio J, Heinemann V, Picard P, Bury D, Drea E, Sobrero A.

Clin Colorectal Cancer. 2019 May 15. pii: S1533-0028(19)30023-4. doi: 10.1016/j.clcc.2019.05.003. [Epub ahead of print]


Slow growth of Burkholderia pseudomallei compared to other pathogens in an adapted blood culture system in Phnom Penh, Cambodia.

Peeters M, Ombelet S, Chung P, Tsoumanis A, Lim K, Long L, De Smet B, Kham C, Teav S, Vlieghe E, Phe T, Jacobs J.

J Med Microbiol. 2019 Jun 12. doi: 10.1099/jmm.0.001011. [Epub ahead of print]


Towards risk-stratified colorectal cancer screening. Adding risk factors to the fecal immunochemical test: Evidence, evolution and expectations.

van de Veerdonk W, Hoeck S, Peeters M, Van Hal G.

Prev Med. 2019 Jun 4;126:105746. doi: 10.1016/j.ypmed.2019.06.004. [Epub ahead of print] Review.


Synthesis of Optimized Molecularly Imprinted Polymers for the Isolation and Detection of Antidepressants via HPLC.

Hudson AD, Solà R, Ueta JT, Battell W, Jamieson O, Dunbar T, Maciá B, Peeters M.

Biomimetics (Basel). 2019 Feb 20;4(1). pii: E18. doi: 10.3390/biomimetics4010018.


Bioinspired Materials 2018: Conference Report.

Peeters M, Linton P, Hidalgo-Bastida A.

Biomimetics (Basel). 2019 Jan 14;4(1). pii: E4. doi: 10.3390/biomimetics4010004.


RANK-RANKL Signaling in Cancer of the Uterine Cervix: A Review.

van Dam PA, Verhoeven Y, Jacobs J, Wouters A, Tjalma W, Lardon F, Van den Wyngaert T, Dewulf J, Smits E, Colpaert C, Prenen H, Peeters M, Lammens M, Trinh XB.

Int J Mol Sci. 2019 May 2;20(9). pii: E2183. doi: 10.3390/ijms20092183. Review.


Evaluating the feasibility of a nurse-led self-management support intervention for kidney transplant recipients: a pilot study.

Been-Dahmen JMJ, Beck DK, Peeters MAC, van der Stege H, Tielen M, van Buren MC, Ista E, van Staa A, Massey EK.

BMC Nephrol. 2019 Apr 27;20(1):143. doi: 10.1186/s12882-019-1300-7.


2018 Ebola virus disease outbreak in Équateur Province, Democratic Republic of the Congo: a retrospective genomic characterisation.

Mbala-Kingebeni P, Pratt CB, Wiley MR, Diagne MM, Makiala-Mandanda S, Aziza A, Di Paola N, Chitty JA, Diop M, Ayouba A, Vidal N, Faye O, Faye O, Karhemere S, Aruna A, Nsio J, Mulangu F, Mukadi D, Mukadi P, Kombe J, Mulumba A, Duraffour S, Likofata J, Pukuta E, Caviness K, Bartlett ML, Gonzalez J, Minogue T, Sozhamannan S, Gross SM, Schroth GP, Kuhn JH, Donaldson EF, Delaporte E, Sanchez-Lockhart M, Peeters M, Muyembe-Tamfum JJ, Alpha Sall A, Palacios G, Ahuka-Mundeke S.

Lancet Infect Dis. 2019 Jun;19(6):641-647. doi: 10.1016/S1473-3099(19)30124-0. Epub 2019 Apr 15.


Medical countermeasures during the 2018 Ebola virus disease outbreak in the North Kivu and Ituri Provinces of the Democratic Republic of the Congo: a rapid genomic assessment.

Mbala-Kingebeni P, Aziza A, Di Paola N, Wiley MR, Makiala-Mandanda S, Caviness K, Pratt CB, Ladner JT, Kugelman JR, Prieto K, Chitty JA, Larson PA, Beitzel B, Ayouba A, Vidal N, Karhemere S, Diop M, Diagne MM, Faye M, Faye O, Aruna A, Nsio J, Mulangu F, Mukadi D, Mukadi P, Kombe J, Mulumba A, Villabona-Arenas CJ, Pukuta E, Gonzalez J, Bartlett ML, Sozhamannan S, Gross SM, Schroth GP, Tim R, Zhao JJ, Kuhn JH, Diallo B, Yao M, Fall IS, Ndjoloko B, Mossoko M, Lacroix A, Delaporte E, Sanchez-Lockhart M, Sall AA, Muyembe-Tamfum JJ, Peeters M, Palacios G, Ahuka-Mundeke S.

Lancet Infect Dis. 2019 Jun;19(6):648-657. doi: 10.1016/S1473-3099(19)30118-5. Epub 2019 Apr 15.


Methylation analysis of Gasdermin E shows great promise as a biomarker for colorectal cancer.

Ibrahim J, Op de Beeck K, Fransen E, Croes L, Beyens M, Suls A, Vanden Berghe W, Peeters M, Van Camp G.

Cancer Med. 2019 May;8(5):2133-2145. doi: 10.1002/cam4.2103. Epub 2019 Apr 16.


Earlier Initiation of Antiretroviral Treatment Coincides With an Initial Control of the HIV-1 Sub-Subtype F1 Outbreak Among Men-Having-Sex-With-Men in Flanders, Belgium.

Vinken L, Fransen K, Cuypers L, Alexiev I, Balotta C, Debaisieux L, Seguin-Devaux C, García Ribas S, Gomes P, Incardona F, Kaiser R, Ruelle J, Sayan M, Paraschiv S, Paredes R, Peeters M, Sönnerborg A, Vancutsem E, Vandamme AM, Van den Wijngaert S, Van Ranst M, Verhofstede C, Stadler T, Lemey P, Van Laethem K.

Front Microbiol. 2019 Mar 26;10:613. doi: 10.3389/fmicb.2019.00613. eCollection 2019.


Circulating Cell-Free DNA and RNA Analysis as Liquid Biopsy: Optimal Centrifugation Protocol.

Sorber L, Zwaenepoel K, Jacobs J, De Winne K, Goethals S, Reclusa P, Van Casteren K, Augustus E, Lardon F, Roeyen G, Peeters M, Van Meerbeeck J, Rolfo C, Pauwels P.

Cancers (Basel). 2019 Mar 30;11(4). pii: E458. doi: 10.3390/cancers11040458.


Meeting Report on the Conference on Fathers' Role in Children's Weight-Related Behaviors and Outcomes.

Peeters M, Davison K, Ma D, Haines J.

Obesity (Silver Spring). 2019 Apr;27(4):523-524. doi: 10.1002/oby.22396.


Binimetinib, Encorafenib, and Cetuximab Triplet Therapy for Patients With BRAF V600E-Mutant Metastatic Colorectal Cancer: Safety Lead-In Results From the Phase III BEACON Colorectal Cancer Study.

Van Cutsem E, Huijberts S, Grothey A, Yaeger R, Cuyle PJ, Elez E, Fakih M, Montagut C, Peeters M, Yoshino T, Wasan H, Desai J, Ciardiello F, Gollerkeri A, Christy-Bittel J, Maharry K, Sandor V, Schellens JHM, Kopetz S, Tabernero J.

J Clin Oncol. 2019 Jun 10;37(17):1460-1469. doi: 10.1200/JCO.18.02459. Epub 2019 Mar 20.


The Vital Worker: Towards Sustainable Performance at Work.

de Jonge J, Peeters MCW.

Int J Environ Res Public Health. 2019 Mar 13;16(6). pii: E910. doi: 10.3390/ijerph16060910.


In vitro study of the Polo-like kinase 1 inhibitor volasertib in non-small-cell lung cancer reveals a role for the tumor suppressor p53.

Van den Bossche J, Deben C, De Pauw I, Lambrechts H, Hermans C, Deschoolmeester V, Jacobs J, Specenier P, Pauwels P, Vermorken JB, Peeters M, Lardon F, Wouters A.

Mol Oncol. 2019 May;13(5):1196-1213. doi: 10.1002/1878-0261.12477. Epub 2019 Apr 5.


Recent Advances in Electrosynthesized Molecularly Imprinted Polymer Sensing Platforms for Bioanalyte Detection.

Crapnell RD, Hudson A, Foster CW, Eersels K, Grinsven BV, Cleij TJ, Banks CE, Peeters M.

Sensors (Basel). 2019 Mar 9;19(5). pii: E1204. doi: 10.3390/s19051204. Review.


A Nurse-Led Self-Management Support Intervention (ZENN) for Kidney Transplant Recipients Using Intervention Mapping: Protocol for a Mixed-Methods Feasibility Study.

Beck D, Been-Dahmen J, Peeters M, Grijpma JW, van der Stege H, Tielen M, van Buren M, Weimar W, Ista E, Massey E, van Staa A.

JMIR Res Protoc. 2019 Mar 1;8(3):e11856. doi: 10.2196/11856.


Drivers of year-to-year variation in exacerbation frequency of COPD: analysis of the AERIS cohort.

Wilkinson TMA, Aris E, Bourne SC, Clarke SC, Peeters M, Pascal TG, Taddei L, Tuck AC, Kim VL, Ostridge KK, Staples KJ, Williams NP, Williams AP, Wootton SA, Devaster JM.

ERJ Open Res. 2019 Feb 25;5(1). pii: 00248-2018. doi: 10.1183/23120541.00248-2018. eCollection 2019 Feb.


Evolution of self-perceived swallowing function, tongue strength and swallow-related quality of life during radiotherapy in head and neck cancer patients.

Van den Steen L, Van Gestel D, Vanderveken O, Vanderwegen J, Lazarus C, Daisne JF, Van Laer C, Specenier P, Van Rompaey D, Mariën S, Lawson G, Chantrain G, Desuter G, Van den Weyngaert D, Cvilic S, Beauvois S, Allouche J, Delacroix L, Vermorken JB, Peeters M, Dragan T, Van de Heyning P, De Bodt M, Van Nuffelen G.

Head Neck. 2019 Jul;41(7):2197-2207. doi: 10.1002/hed.25684. Epub 2019 Feb 14.


Prevalence of infection among asymptomatic and paucisymptomatic contact persons exposed to Ebola virus in Guinea: a retrospective, cross-sectional observational study.

Diallo MSK, Rabilloud M, Ayouba A, Touré A, Thaurignac G, Keita AK, Butel C, Kpamou C, Barry TA, Sall MD, Camara I, Leroy S, Msellati P, Ecochard R, Peeters M, Sow MS, Delaporte E, Etard JF; Contactebogui Study Group.

Lancet Infect Dis. 2019 Mar;19(3):308-316. doi: 10.1016/S1473-3099(18)30649-2. Epub 2019 Feb 11.


Prognostic value of adipose tissue and muscle mass in advanced colorectal cancer: a post hoc analysis of two non-randomized phase II trials.

Charette N, Vandeputte C, Ameye L, Bogaert CV, Krygier J, Guiot T, Deleporte A, Delaunoit T, Geboes K, Van Laethem JL, Peeters M, Demolin G, Holbrechts S, Flamen P, Paesmans M, Hendlisz A.

BMC Cancer. 2019 Feb 12;19(1):134. doi: 10.1186/s12885-019-5319-8.


High level of treatment failure and drug resistance to first-line antiretroviral therapies among HIV-infected children receiving decentralized care in Senegal.

Cissé AM, Laborde-Balen G, Kébé-Fall K, Dramé A, Diop H, Diop K, FatouNiasse-Traoré, Coulibaly M, Have NN, Vidal N, Thiam S, Wade AS, Peeters M, Taverne B, Msellati P, Touré-Kane C.

BMC Pediatr. 2019 Feb 5;19(1):47. doi: 10.1186/s12887-019-1420-z.


CD4 receptor diversity in chimpanzees protects against SIV infection.

Bibollet-Ruche F, Russell RM, Liu W, Stewart-Jones GBE, Sherrill-Mix S, Li Y, Learn GH, Smith AG, Gondim MVP, Plenderleith LJ, Decker JM, Easlick JL, Wetzel KS, Collman RG, Ding S, Finzi A, Ayouba A, Peeters M, Leendertz FH, van Schijndel J, Goedmakers A, Ton E, Boesch C, Kuehl H, Arandjelovic M, Dieguez P, Murai M, Colin C, Koops K, Speede S, Gonder MK, Muller MN, Sanz CM, Morgan DB, Atencia R, Cox D, Piel AK, Stewart FA, Ndjango JN, Mjungu D, Lonsdorf EV, Pusey AE, Kwong PD, Sharp PM, Shaw GM, Hahn BH.

Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):3229-3238. doi: 10.1073/pnas.1821197116. Epub 2019 Feb 4.


Understanding Ebola virus and other zoonotic transmission risks through human-bat contacts: Exploratory study on knowledge, attitudes and practices in Southern Cameroon.

Baudel H, De Nys H, Mpoudi Ngole E, Peeters M, Desclaux A.

Zoonoses Public Health. 2019 May;66(3):288-295. doi: 10.1111/zph.12563. Epub 2019 Jan 24.


Extensive serological survey of multiple African non-human primate species reveals low prevalence of IgG antibodies to four Ebola virus species.

Ayouba A, Ahuka-Mundeke S, Butel C, Mbala Kingebeni P, Loul S, Tagg N, Arenas CV, Lacroix A, Ndimbo-Kumugo SP, Keita AK, Toure A, Couacy-Hymann E, Calvignac-Spencer S, Leendertz FH, Formenty P, Delaporte E, Muyembe-Tamfum JJ, Ngole EM, Peeters M.

J Infect Dis. 2019 Jan 18. doi: 10.1093/infdis/jiz006. [Epub ahead of print]


Overcoming Intrinsic and Acquired Cetuximab Resistance in RAS Wild-Type Colorectal Cancer: An In Vitro Study on the Expression of HER Receptors and the Potential of Afatinib.

De Pauw I, Lardon F, Van den Bossche J, Baysal H, Pauwels P, Peeters M, Vermorken JB, Wouters A.

Cancers (Basel). 2019 Jan 15;11(1). pii: E98. doi: 10.3390/cancers11010098.


Hospital transfer after a breast cancer diagnosis: A population-based study in the Netherlands of the extent, predictive characteristics and its impact on time to treatment.

Heeg E, Schreuder K, Spronk PER, Oosterwijk JC, Marang-van de Mheen PJ, Siesling S, Peeters MTFDV; NABON Breast Cancer Audit.

Eur J Surg Oncol. 2019 Apr;45(4):560-566. doi: 10.1016/j.ejso.2018.12.017. Epub 2018 Dec 29.


A databank for intracellular electrophysiological mapping of the adult somatosensory cortex.

da Silva Lantyer A, Calcini N, Bijlsma A, Kole K, Emmelkamp M, Peeters M, Scheenen WJJ, Zeldenrust F, Celikel T.

Gigascience. 2018 Dec 1;7(12). doi: 10.1093/gigascience/giy147.


Noninvasive western lowland gorilla's health monitoring: A decade of simian immunodeficiency virus surveillance in southern Cameroon.

Villabona-Arenas CJ, Ayouba A, Esteban A, D'arc M, Mpoudi Ngole E, Peeters M.

Ecol Evol. 2018 Oct 25;8(22):10698-10710. doi: 10.1002/ece3.4478. eCollection 2018 Nov.


Evaluation of Emergent Mutations in Circulating Cell-Free DNA and Clinical Outcomes in Patients with Metastatic Colorectal Cancer Treated with Panitumumab in the ASPECCT Study.

Peeters M, Price T, Boedigheimer M, Kim TW, Ruff P, Gibbs P, Thomas A, Demonty G, Hool K, Ang A.

Clin Cancer Res. 2019 Feb 15;25(4):1216-1225. doi: 10.1158/1078-0432.CCR-18-2072. Epub 2018 Nov 28.


Cell-Free DNA From Metastatic Pancreatic Neuroendocrine Tumor Patients Contains Tumor-Specific Mutations and Copy Number Variations.

Boons G, Vandamme T, Peeters M, Beyens M, Driessen A, Janssens K, Zwaenepoel K, Roeyen G, Van Camp G, Op de Beeck K.

Front Oncol. 2018 Nov 1;8:467. doi: 10.3389/fonc.2018.00467. eCollection 2018.


Prevalence of pretreatment HIV drug resistance in West African and Southeast Asian countries.

Ngo-Giang-Huong N, Huynh THK, Dagnra AY, Toni TD, Maiga AI, Kania D, Eymard-Duvernay S, Peeters M, Soulie C, Peytavin G, Rekacewicz C, Chaix ML, Aghokeng AF; ANRS 12333 Study Group .

J Antimicrob Chemother. 2019 Feb 1;74(2):462-467. doi: 10.1093/jac/dky443.


Using Rasch Measurement to Revisit Survey Checklist Items.

Peeters MJ, Beltyukova SA.

Acad Med. 2018 Nov;93(11):1603. doi: 10.1097/ACM.0000000000002421. No abstract available.


Survey of Ebola Viruses in Frugivorous and Insectivorous Bats in Guinea, Cameroon, and the Democratic Republic of the Congo, 2015-2017.

De Nys HM, Kingebeni PM, Keita AK, Butel C, Thaurignac G, Villabona-Arenas CJ, Lemarcis T, Geraerts M, Vidal N, Esteban A, Bourgarel M, Roger F, Leendertz F, Diallo R, Ndimbo-Kumugo SP, Nsio-Mbeta J, Tagg N, Koivogui L, Toure A, Delaporte E, Ahuka-Mundeke S, Tamfum JM, Mpoudi-Ngole E, Ayouba A, Peeters M.

Emerg Infect Dis. 2018 Dec;24(12):2228-2240. doi: 10.3201/eid2412.180740. Epub 2018 Dec 17.


Pisces: an accurate and versatile variant caller for somatic and germline next-generation sequencing data.

Dunn T, Berry G, Emig-Agius D, Jiang Y, Lei S, Iyer A, Udar N, Chuang HY, Hegarty J, Dickover M, Klotzle B, Robbins J, Bibikova M, Peeters M, Strömberg M.

Bioinformatics. 2019 May 1;35(9):1579-1581. doi: 10.1093/bioinformatics/bty849.


Authenticity at Work: A Matter of Fit?

van den Bosch R, Taris TW, Schaufeli WB, Peeters MCW, Reijseger G.

J Psychol. 2019;153(2):247-266. doi: 10.1080/00223980.2018.1516185. Epub 2018 Oct 4.


Unmet Needs in Functional and Nonfunctional Pancreatic Neuroendocrine Neoplasms.

Jensen RT, Bodei L, Capdevila J, Couvelard A, Falconi M, Glasberg S, Kloppel G, Lamberts S, Peeters M, Rindi G, Rinke A, Rothmund M, Sundin A, Welin S, Fazio N; The ENETS 2016 Munich Advisory Board Participants; ENETS 2016 Munich Advisory Board Participants.

Neuroendocrinology. 2019;108(1):26-36. doi: 10.1159/000494258. Epub 2018 Oct 3.


Bidirectional effects of Internet-specific parenting practices and compulsive social media and Internet game use.

Koning IM, Peeters M, Finkenauer C, van den Eijnden RJJM.

J Behav Addict. 2018 Sep 1;7(3):624-632. doi: 10.1556/2006.7.2018.68.


Development of critical thinking in health professions education: A meta-analysis of longitudinal studies.

Reale MC, Riche DM, Witt BA, Baker WL, Peeters MJ.

Curr Pharm Teach Learn. 2018 Jul;10(7):826-833. doi: 10.1016/j.cptl.2018.04.019. Epub 2018 Apr 26.


Regorafenib for Patients with Metastatic Colorectal Cancer Who Progressed After Standard Therapy: Results of the Large, Single-Arm, Open-Label Phase IIIb CONSIGN Study.

Van Cutsem E, Martinelli E, Cascinu S, Sobrero A, Banzi M, Seitz JF, Barone C, Ychou M, Peeters M, Brenner B, Hofheinz RD, Maiello E, André T, Spallanzani A, Garcia-Carbonero R, Arriaga YE, Verma U, Grothey A, Kappeler C, Miriyala A, Kalmus J, Falcone A, Zaniboni A.

Oncologist. 2019 Feb;24(2):185-192. doi: 10.1634/theoncologist.2018-0072. Epub 2018 Sep 6.


Unmet Medical Needs in Metastatic Lung and Digestive Neuroendocrine Neoplasms.

Capdevila J, Bodei L, Davies P, Gorbounova V, Jensen RT, Knigge UP, Krejs GJ, Krenning E, O'Connor JM, Peeters M, Rindi G, Salazar R, Vullierme MP, Pavel ME; ENETS 2016 Munich Advisory Board Participants; ENETS 2016 Munich Advisory Board Participants.

Neuroendocrinology. 2019;108(1):18-25. doi: 10.1159/000493319. Epub 2018 Aug 28.


Evolutionary history of human Plasmodium vivax revealed by genome-wide analyses of related ape parasites.

Loy DE, Plenderleith LJ, Sundararaman SA, Liu W, Gruszczyk J, Chen YJ, Trimboli S, Learn GH, MacLean OA, Morgan ALK, Li Y, Avitto AN, Giles J, Calvignac-Spencer S, Sachse A, Leendertz FH, Speede S, Ayouba A, Peeters M, Rayner JC, Tham WH, Sharp PM, Hahn BH.

Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):E8450-E8459. doi: 10.1073/pnas.1810053115. Epub 2018 Aug 20.


SIVcol Nef counteracts SERINC5 by promoting its proteasomal degradation but does not efficiently enhance HIV-1 replication in human CD4+ T cells and lymphoid tissue.

Kmiec D, Akbil B, Ananth S, Hotter D, Sparrer KMJ, Stürzel CM, Trautz B, Ayouba A, Peeters M, Yao Z, Stagljar I, Passos V, Zillinger T, Goffinet C, Sauter D, Fackler OT, Kirchhoff F.

PLoS Pathog. 2018 Aug 20;14(8):e1007269. doi: 10.1371/journal.ppat.1007269. eCollection 2018 Aug.


Support Needs of People With Head and Neck Cancer Regarding the Disease and Its Treatment.

Peeters MAC, Braat C, Been-Dahmen JMJ, Verduijn GM, Oldenmenger WH, van Staa A.

Oncol Nurs Forum. 2018 Sep 1;45(5):587-596. doi: 10.1188/18.ONF.587-596.


Risk stratification for colorectal neoplasia detection in the Flemish colorectal cancer screening programme.

van de Veerdonk W, Van Hal G, Peeters M, De Brabander I, Silversmit G, Hoeck S.

Cancer Epidemiol. 2018 Oct;56:90-96. doi: 10.1016/j.canep.2018.07.015. Epub 2018 Aug 13.


Multidisciplinary molecular tumour board: a tool to improve clinical practice and selection accrual for clinical trials in patients with cancer.

Rolfo C, Manca P, Salgado R, Van Dam P, Dendooven A, Machado Coelho A, Ferri Gandia J, Rutten A, Lybaert W, Vermeij J, Gevaert T, Weyn C, Lefebure A, Metsu S, Van Laere S, Peeters M, Pauwels P.

ESMO Open. 2018 Jul 23;3(5):e000398. doi: 10.1136/esmoopen-2018-000398. eCollection 2018.


Effect of Primary Tumor Side on Survival Outcomes in Untreated Patients With Metastatic Colorectal Cancer When Selective Internal Radiation Therapy Is Added to Chemotherapy: Combined Analysis of Two Randomized Controlled Studies.

Gibbs P, Heinemann V, Sharma NK, Taieb J, Ricke J, Peeters M, Findlay M, Robinson B, Jackson C, Strickland A, Gebski V, Van Buskirk M, Zhao H, van Hazel G; SIRFLOX and FOXFIRE Global Trial Investigators.

Clin Colorectal Cancer. 2018 Dec;17(4):e617-e629. doi: 10.1016/j.clcc.2018.06.001. Epub 2018 Jun 12.


Patient empowerment in young persons with chronic conditions: Psychometric properties of the Gothenburg Young Persons Empowerment Scale (GYPES).

Acuña Mora M, Luyckx K, Sparud-Lundin C, Peeters M, van Staa A, Sattoe J, Bratt EL, Moons P.

PLoS One. 2018 Jul 20;13(7):e0201007. doi: 10.1371/journal.pone.0201007. eCollection 2018.

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