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Items: 1 to 50 of 125

1.

The continuous heart failure spectrum: moving beyond an ejection fraction classification.

Triposkiadis F, Butler J, Abboud FM, Armstrong PW, Adamopoulos S, Atherton JJ, Backs J, Bauersachs J, Burkhoff D, Bonow RO, Chopra VK, de Boer RA, de Windt L, Hamdani N, Hasenfuss G, Heymans S, Hulot JS, Konstam M, Lee RT, Linke WA, Lunde IG, Lyon AR, Maack C, Mann DL, Mebazaa A, Mentz RJ, Nihoyannopoulos P, Papp Z, Parissis J, Pedrazzini T, Rosano G, Rouleau J, Seferovic PM, Shah AM, Starling RC, Tocchetti CG, Trochu JN, Thum T, Zannad F, Brutsaert DL, Segers VF, De Keulenaer GW.

Eur Heart J. 2019 Jul 1;40(26):2155-2163. doi: 10.1093/eurheartj/ehz158.

PMID:
30957868
2.

Catalyzing Transcriptomics Research in Cardiovascular Disease: The CardioRNA COST Action CA17129.

Gomes CPC, Ágg B, Andova A, Arslan S, Baker A, Barteková M, Beis D, Betsou F, Wettinger SB, Bugarski B, Condorelli G, Silva GJJD, Danilin S, de Gonzalo-Calvo D, Buil A, Carmo-Fonseca M, Enguita FJ, Felekkis K, Ferdinandy P, Gyöngyösi M, Hackl M, Karaduzovic-Hadziabdic K, Hellemans J, Heymans S, Hlavackova M, Hoydal MA, Jankovic A, Jusic A, Kardassis D, Kerkelä R, Kuster GM, Lakkisto P, Leszek P, Lustrek M, Maegdefessel L, Martelli F, Novella S, O'Brien T, Papaneophytou C, Pedrazzini T, Pinet F, Popescu O, Potočnjak I, Robinson E, Sasson S, Scholz M, Simionescu M, Stoll M, Varga ZV, Vinciguerra M, Xuereb A, Yilmaz MB, Emanueli C, Devaux Y, on behalf of the EU-CardioRNA COST Action (CA17129).

Noncoding RNA. 2019 Mar 29;5(2). pii: E31. doi: 10.3390/ncrna5020031.

3.

Inhibition of the Hypoxia-Inducible Factor 1α-Induced Cardiospecific HERNA1 Enhance-Templated RNA Protects From Heart Disease.

Mirtschink P, Bischof C, Pham MD, Sharma R, Khadayate S, Rossi G, Fankhauser N, Traub S, Sossalla S, Hagag E, Berthonneche C, Sarre A, Stehr SN, Grote P, Pedrazzini T, Dimmeler S, Krek W, Krishnan J.

Circulation. 2019 Jun 11;139(24):2778-2792. doi: 10.1161/CIRCULATIONAHA.118.036769. Epub 2019 Mar 29.

4.

ALDH1A3 Is the Key Isoform That Contributes to Aldehyde Dehydrogenase Activity and Affects in Vitro Proliferation in Cardiac Atrial Appendage Progenitor Cells.

Puttini S, Plaisance I, Barile L, Cervio E, Milano G, Marcato P, Pedrazzini T, Vassalli G.

Front Cardiovasc Med. 2018 Jul 24;5:90. doi: 10.3389/fcvm.2018.00090. eCollection 2018.

5.

A transcribed enhancer dictates mesendoderm specification in pluripotency.

Alexanian M, Maric D, Jenkinson SP, Mina M, Friedman CE, Ting CC, Micheletti R, Plaisance I, Nemir M, Maison D, Kernen J, Pezzuto I, Villeneuve D, Burdet F, Ibberson M, Leib SL, Palpant NJ, Hernandez N, Ounzain S, Pedrazzini T.

Nat Commun. 2017 Nov 27;8(1):1806. doi: 10.1038/s41467-017-01804-w.

6.

The long noncoding RNA Wisper controls cardiac fibrosis and remodeling.

Micheletti R, Plaisance I, Abraham BJ, Sarre A, Ting CC, Alexanian M, Maric D, Maison D, Nemir M, Young RA, Schroen B, González A, Ounzain S, Pedrazzini T.

Sci Transl Med. 2017 Jun 21;9(395). pii: eaai9118. doi: 10.1126/scitranslmed.aai9118.

7.

New Lncs to mesendoderm specification.

Alexanian M, Pedrazzini T, Ounzain S.

J Thorac Dis. 2017 Mar;9(Suppl 1):S5-S8. doi: 10.21037/jtd.2017.03.70. Review.

8.

Cardiomyocyte Lineage Specification in Adult Human Cardiac Precursor Cells Via Modulation of Enhancer-Associated Long Noncoding RNA Expression.

Plaisance I, Perruchoud S, Fernandez-Tenorio M, Gonzales C, Ounzain S, Ruchat P, Nemir M, Niggli E, Pedrazzini T.

JACC Basic Transl Sci. 2016 Oct;1(6):472-493. doi: 10.1016/j.jacbts.2016.06.008.

9.

Long non-coding RNAs in heart failure: a promising future with much to learn.

Ounzain S, Pedrazzini T.

Ann Transl Med. 2016 Aug;4(15):298. doi: 10.21037/atm.2016.07.13. No abstract available.

10.

Divergent Paths Lnc Cell Fates.

Ounzain S, Pedrazzini T.

Cell Stem Cell. 2016 May 5;18(5):561-2. doi: 10.1016/j.stem.2016.04.005.

11.

Comparative transcriptome profiling of the injured zebrafish and mouse hearts identifies miRNA-dependent repair pathways.

Crippa S, Nemir M, Ounzain S, Ibberson M, Berthonneche C, Sarre A, Boisset G, Maison D, Harshman K, Xenarios I, Diviani D, Schorderet D, Pedrazzini T.

Cardiovasc Res. 2016 May 1;110(1):73-84. doi: 10.1093/cvr/cvw031. Epub 2016 Feb 7.

12.

Super-enhancer lncs to cardiovascular development and disease.

Ounzain S, Pedrazzini T.

Biochim Biophys Acta. 2016 Jul;1863(7 Pt B):1953-60. doi: 10.1016/j.bbamcr.2015.11.026. Epub 2015 Nov 24. Review.

13.

Cardiac mTOR complex 2 preserves ventricular function in pressure-overload hypertrophy.

Shende P, Xu L, Morandi C, Pentassuglia L, Heim P, Lebboukh S, Berthonneche C, Pedrazzini T, Kaufmann BA, Hall MN, Rüegg MA, Brink M.

Cardiovasc Res. 2016 Jan 1;109(1):103-14. doi: 10.1093/cvr/cvv252. Epub 2015 Nov 23.

PMID:
26598511
14.

CARMEN, a human super enhancer-associated long noncoding RNA controlling cardiac specification, differentiation and homeostasis.

Ounzain S, Micheletti R, Arnan C, Plaisance I, Cecchi D, Schroen B, Reverter F, Alexanian M, Gonzales C, Ng SY, Bussotti G, Pezzuto I, Notredame C, Heymans S, Guigó R, Johnson R, Pedrazzini T.

J Mol Cell Cardiol. 2015 Dec;89(Pt A):98-112. doi: 10.1016/j.yjmcc.2015.09.016. Epub 2015 Sep 28.

15.

Discovery and functional characterization of cardiovascular long noncoding RNAs.

Ounzain S, Burdet F, Ibberson M, Pedrazzini T.

J Mol Cell Cardiol. 2015 Dec;89(Pt A):17-26. doi: 10.1016/j.yjmcc.2015.09.013. Epub 2015 Sep 25. Review.

16.

Jagged1 intracellular domain-mediated inhibition of Notch1 signalling regulates cardiac homeostasis in the postnatal heart.

Metrich M, Bezdek Pomey A, Berthonneche C, Sarre A, Nemir M, Pedrazzini T.

Cardiovasc Res. 2015 Oct 1;108(1):74-86. doi: 10.1093/cvr/cvv209. Epub 2015 Aug 6.

17.

HIF-driven SF3B1 induces KHK-C to enforce fructolysis and heart disease.

Mirtschink P, Krishnan J, Grimm F, Sarre A, Hörl M, Kayikci M, Fankhauser N, Christinat Y, Cortijo C, Feehan O, Vukolic A, Sossalla S, Stehr SN, Ule J, Zamboni N, Pedrazzini T, Krek W.

Nature. 2015 Jun 25;522(7557):444-449. doi: 10.1038/nature14508. Epub 2015 Jun 17.

18.

Long noncoding RNAs in cardiac development and ageing.

Devaux Y, Zangrando J, Schroen B, Creemers EE, Pedrazzini T, Chang CP, Dorn GW 2nd, Thum T, Heymans S; Cardiolinc network.

Nat Rev Cardiol. 2015 Jul;12(7):415-25. doi: 10.1038/nrcardio.2015.55. Epub 2015 Apr 7. Review.

PMID:
25855606
19.

[In the heart of noncoding RNA: a long way to go].

Pedrazzini T.

Med Sci (Paris). 2015 Mar;31(3):261-7. doi: 10.1051/medsci/20153103011. Epub 2015 Apr 8. French.

20.

The promise of enhancer-associated long noncoding RNAs in cardiac regeneration.

Ounzain S, Pedrazzini T.

Trends Cardiovasc Med. 2015 Oct;25(7):592-602. doi: 10.1016/j.tcm.2015.01.014. Epub 2015 Feb 7. Review.

21.

Functional importance of cardiac enhancer-associated noncoding RNAs in heart development and disease.

Ounzain S, Pezzuto I, Micheletti R, Burdet F, Sheta R, Nemir M, Gonzales C, Sarre A, Alexanian M, Blow MJ, May D, Johnson R, Dauvillier J, Pennacchio LA, Pedrazzini T.

J Mol Cell Cardiol. 2014 Nov;76:55-70. doi: 10.1016/j.yjmcc.2014.08.009. Epub 2014 Aug 19.

22.

[Silver(I)(pyridine-containing ligand)] complexes as unusual catalysts for A(3)-coupling reactions.

Trose M, Dell'Acqua M, Pedrazzini T, Pirovano V, Gallo E, Rossi E, Caselli A, Abbiati G.

J Org Chem. 2014 Aug 15;79(16):7311-20. doi: 10.1021/jo500981r. Epub 2014 Aug 4.

23.

Genome-wide profiling of the cardiac transcriptome after myocardial infarction identifies novel heart-specific long non-coding RNAs.

Ounzain S, Micheletti R, Beckmann T, Schroen B, Alexanian M, Pezzuto I, Crippa S, Nemir M, Sarre A, Johnson R, Dauvillier J, Burdet F, Ibberson M, Guigó R, Xenarios I, Heymans S, Pedrazzini T.

Eur Heart J. 2015 Feb 7;36(6):353-68a. doi: 10.1093/eurheartj/ehu180. Epub 2014 Apr 30.

24.

Mild regiospecific synthesis of 1-alkoxy-isochromenes catalyzed by well-defined [silver(I)(pyridine-containing ligand)] complexes.

Dell'Acqua M, Castano B, Cecchini C, Pedrazzini T, Pirovano V, Rossi E, Caselli A, Abbiati G.

J Org Chem. 2014 Apr 18;79(8):3494-505. doi: 10.1021/jo5002559. Epub 2014 Mar 31.

25.

Ageing-related cardiomyocyte functional decline is sex and angiotensin II dependent.

Mellor KM, Curl CL, Chandramouli C, Pedrazzini T, Wendt IR, Delbridge LM.

Age (Dordr). 2014 Jun;36(3):9630. doi: 10.1007/s11357-014-9630-7. Epub 2014 Feb 25.

26.

Meeting highlights from the 2013 European Society of Cardiology Heart Failure Association Winter Meeting on Translational Heart Failure Research.

Hohl M, Ardehali H, Azuaje FJ, Breckenridge RA, Doehner W, Eaton P, Ehret GB, Fujita T, Gaetani R, Giacca M, Hasenfuß G, Heymans S, Leite-Moreira AF, Linke WA, Linz D, Lyon A, Mamas MA, Orešič M, Papp Z, Pedrazzini T, Piepoli M, Prosser B, Rizzuto R, Tarone G, Tian R, van Craenenbroeck E, van Rooij E, Wai T, Weiss G, Maack C.

Eur J Heart Fail. 2014 Jan;16(1):6-14. doi: 10.1002/ejhf.10. Epub 2013 Dec 14. Review. No abstract available.

27.

The AP-1 transcription factor c-Jun prevents stress-imposed maladaptive remodeling of the heart.

Windak R, Müller J, Felley A, Akhmedov A, Wagner EF, Pedrazzini T, Sumara G, Ricci R.

PLoS One. 2013 Sep 10;8(9):e73294. doi: 10.1371/journal.pone.0073294. eCollection 2013.

28.

The Notch pathway controls fibrotic and regenerative repair in the adult heart.

Nemir M, Metrich M, Plaisance I, Lepore M, Cruchet S, Berthonneche C, Sarre A, Radtke F, Pedrazzini T.

Eur Heart J. 2014 Aug 21;35(32):2174-85. doi: 10.1093/eurheartj/ehs269. Epub 2012 Nov 19.

29.

Nitric oxide synthase 2 is required for conversion of pro-fibrogenic inflammatory CD133(+) progenitors into F4/80(+) macrophages in experimental autoimmune myocarditis.

Blyszczuk P, Berthonneche C, Behnke S, Glönkler M, Moch H, Pedrazzini T, Lüscher TF, Eriksson U, Kania G.

Cardiovasc Res. 2013 Feb 1;97(2):219-29. doi: 10.1093/cvr/cvs317. Epub 2012 Oct 22.

30.

Small and long non-coding RNAs in cardiac homeostasis and regeneration.

Ounzain S, Crippa S, Pedrazzini T.

Biochim Biophys Acta. 2013 Apr;1833(4):923-33. doi: 10.1016/j.bbamcr.2012.08.010. Epub 2012 Aug 23. Review.

31.

Mapping genetic variants associated with beta-adrenergic responses in inbred mice.

Hersch M, Peter B, Kang HM, Schüpfer F, Abriel H, Pedrazzini T, Eskin E, Beckmann JS, Bergmann S, Maurer F.

PLoS One. 2012;7(7):e41032. doi: 10.1371/journal.pone.0041032. Epub 2012 Jul 31. Erratum in: PLoS One. 2014;9(1). doi:10.1371/annotation/16d5801b-2701-4ec9-9d8e-278791a8a26a.

32.

Differential effects of high-fat diet on myocardial lipid metabolism in failing and nonfailing hearts with angiotensin II-mediated cardiac remodeling in mice.

Pellieux C, Montessuit C, Papageorgiou I, Pedrazzini T, Lerch R.

Am J Physiol Heart Circ Physiol. 2012 May 1;302(9):H1795-805. doi: 10.1152/ajpheart.01023.2011. Epub 2012 Mar 9.

33.

Impact of salt on cardiac differential gene expression and coronary lesion in normotensive mineralocorticoid-treated mice.

Wang Q, Domenighetti AA, Schäfer SC, Weber J, Simon A, Maillard MP, Pedrazzini T, Chen J, Lehr HA, Burnier M.

Am J Physiol Regul Integr Comp Physiol. 2012 May;302(9):R1025-33. doi: 10.1152/ajpregu.00387.2011. Epub 2012 Mar 7.

34.

Cardiac lineage protein-1 (CLP-1) regulates cardiac remodeling via transcriptional modulation of diverse hypertrophic and fibrotic responses and angiotensin II-transforming growth factor β (TGF-β1) signaling axis.

Mascareno E, Galatioto J, Rozenberg I, Salciccioli L, Kamran H, Lazar JM, Liu F, Pedrazzini T, Siddiqui MA.

J Biol Chem. 2012 Apr 13;287(16):13084-93. doi: 10.1074/jbc.M111.288944. Epub 2012 Feb 3.

35.

Dietary obesity-associated Hif1α activation in adipocytes restricts fatty acid oxidation and energy expenditure via suppression of the Sirt2-NAD+ system.

Krishnan J, Danzer C, Simka T, Ukropec J, Walter KM, Kumpf S, Mirtschink P, Ukropcova B, Gasperikova D, Pedrazzini T, Krek W.

Genes Dev. 2012 Feb 1;26(3):259-70. doi: 10.1101/gad.180406.111.

36.

Cardiac dysfunction and impaired compensatory response to pressure overload in mice deficient in stem cell antigen-1.

Rosenblatt-Velin N, Ogay S, Felley A, Stanford WL, Pedrazzini T.

FASEB J. 2012 Jan;26(1):229-39. doi: 10.1096/fj.11-189605. Epub 2011 Sep 28.

PMID:
21957128
37.

Isolation of cardiovascular precursor cells from the human fetal heart.

Gonzales C, Ullrich ND, Gerber S, Berthonneche C, Niggli E, Pedrazzini T.

Tissue Eng Part A. 2012 Jan;18(1-2):198-207. doi: 10.1089/ten.TEA.2011.0022. Epub 2011 Sep 27.

38.

Cardiac raptor ablation impairs adaptive hypertrophy, alters metabolic gene expression, and causes heart failure in mice.

Shende P, Plaisance I, Morandi C, Pellieux C, Berthonneche C, Zorzato F, Krishnan J, Lerch R, Hall MN, Rüegg MA, Pedrazzini T, Brink M.

Circulation. 2011 Mar 15;123(10):1073-82. doi: 10.1161/CIRCULATIONAHA.110.977066. Epub 2011 Feb 28.

PMID:
21357822
39.

EH-myomesin splice isoform is a novel marker for dilated cardiomyopathy.

Schoenauer R, Emmert MY, Felley A, Ehler E, Brokopp C, Weber B, Nemir M, Faggian GG, Pedrazzini T, Falk V, Hoerstrup SP, Agarkova I.

Basic Res Cardiol. 2011 Mar;106(2):233-47. doi: 10.1007/s00395-010-0131-2. Epub 2010 Nov 11.

40.

Stabilised beta-catenin in postnatal ventricular myocardium leads to dilated cardiomyopathy and premature death.

Hirschy A, Croquelois A, Perriard E, Schoenauer R, Agarkova I, Hoerstrup SP, Taketo MM, Pedrazzini T, Perriard JC, Ehler E.

Basic Res Cardiol. 2010 Sep;105(5):597-608. doi: 10.1007/s00395-010-0101-8. Epub 2010 Apr 8.

41.

Myeloid differentiation factor-88/interleukin-1 signaling controls cardiac fibrosis and heart failure progression in inflammatory dilated cardiomyopathy.

Blyszczuk P, Kania G, Dieterle T, Marty RR, Valaperti A, Berthonneche C, Pedrazzini T, Berger CT, Dirnhofer S, Matter CM, Penninger JM, Lüscher TF, Eriksson U.

Circ Res. 2009 Oct 23;105(9):912-20. doi: 10.1161/CIRCRESAHA.109.199802. Epub 2009 Sep 17.

42.

Progenitor cell therapy for heart disease.

Gonzales C, Pedrazzini T.

Exp Cell Res. 2009 Nov 1;315(18):3077-85. doi: 10.1016/j.yexcr.2009.09.006. Epub 2009 Sep 10. Review.

PMID:
19747911
43.

Cardiovascular response to beta-adrenergic blockade or activation in 23 inbred mouse strains.

Berthonneche C, Peter B, Schüpfer F, Hayoz P, Kutalik Z, Abriel H, Pedrazzini T, Beckmann JS, Bergmann S, Maurer F.

PLoS One. 2009 Aug 12;4(8):e6610. doi: 10.1371/journal.pone.0006610.

44.

Activation of a HIF1alpha-PPARgamma axis underlies the integration of glycolytic and lipid anabolic pathways in pathologic cardiac hypertrophy.

Krishnan J, Suter M, Windak R, Krebs T, Felley A, Montessuit C, Tokarska-Schlattner M, Aasum E, Bogdanova A, Perriard E, Perriard JC, Larsen T, Pedrazzini T, Krek W.

Cell Metab. 2009 Jun;9(6):512-24. doi: 10.1016/j.cmet.2009.05.005.

45.

Angiotensin II-mediated adaptive and maladaptive remodeling of cardiomyocyte excitation-contraction coupling.

Gusev K, Domenighetti AA, Delbridge LM, Pedrazzini T, Niggli E, Egger M.

Circ Res. 2009 Jul 2;105(1):42-50. doi: 10.1161/CIRCRESAHA.108.189779. Epub 2009 May 28. Erratum in: Circ Res. 2009 Sep 11;105(6):e7.

PMID:
19478206
46.

Dietary fish oil is antihypertrophic but does not enhance postischemic myocardial function in female mice.

Huggins CE, Curl CL, Patel R, McLennan PL, Theiss ML, Pedrazzini T, Pepe S, Delbridge LM.

Am J Physiol Heart Circ Physiol. 2009 Apr;296(4):H957-66. doi: 10.1152/ajpheart.01151.2008. Epub 2009 Jan 30.

47.

Control of the adaptive response of the heart to stress via the Notch1 receptor pathway.

Croquelois A, Domenighetti AA, Nemir M, Lepore M, Rosenblatt-Velin N, Radtke F, Pedrazzini T.

J Exp Med. 2008 Dec 22;205(13):3173-85. doi: 10.1084/jem.20081427. Epub 2008 Dec 8.

48.

Y1 receptor knockout increases nociception and prevents the anti-allodynic actions of NPY.

Kuphal KE, Solway B, Pedrazzini T, Taylor BK.

Nutrition. 2008 Sep;24(9):885-91. doi: 10.1016/j.nut.2008.06.022.

49.

S100A1 deficiency results in prolonged ventricular repolarization in response to sympathetic activation.

Ackermann GE, Domenighetti AA, Deten A, Bonath I, Marenholz I, Pedrazzini T, Erne P, Heizmann CW.

Gen Physiol Biophys. 2008 Jun;27(2):127-42.

PMID:
18645228
50.

Overexpression of a mutant form of TGFBI/BIGH3 induces retinal degeneration in transgenic mice.

Bustamante M, Tasinato A, Maurer F, Elkochairi I, Lepore MG, Arsenijevic Y, Pedrazzini T, Munier FL, Schorderet DF.

Mol Vis. 2008 Jun 13;14:1129-37.

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