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Items: 45


Regulat-INGs in tumors and diseases: Focus on ncRNAs.

Gournay M, Paineau M, Archambeau J, Pedeux R.

Cancer Lett. 2019 Apr 10;447:66-74. doi: 10.1016/j.canlet.2019.01.006. Epub 2019 Jan 20.


tert-Butylphenolic Derivatives from Paenibacillus odorifer-A Case of Bioconversion.

Nguyen TB, Delalande O, Rouaud I, Ferron S, Chaillot L, Pedeux R, Tomasi S.

Molecules. 2018 Aug 5;23(8). pii: E1951. doi: 10.3390/molecules23081951.


Human ex vivo prostate tissue model system identifies ING3 as an oncoprotein.

McClurg UL, Nabbi A, Ricordel C, Korolchuk S, McCracken S, Heer R, Wilson L, Butler LM, Irving-Hooper BK, Pedeux R, Robson CN, Riabowol KT, Binda O.

Br J Cancer. 2018 Mar 6;118(5):713-726. doi: 10.1038/bjc.2017.447. Epub 2018 Jan 30.


Brief Report: Proteasomal Indoleamine 2,3-Dioxygenase Degradation Reduces the Immunosuppressive Potential of Clinical Grade-Mesenchymal Stromal Cells Undergoing Replicative Senescence.

Loisel S, Dulong J, Ménard C, Renoud ML, Meziere N, Isabelle B, Latour M, Bescher N, Pedeux R, Bertheuil N, Flecher E, Sensebé L, Tarte K.

Stem Cells. 2017 May;35(5):1431-1436. doi: 10.1002/stem.2580. Epub 2017 Feb 23.


AJP-Cell Physiology begins a theme series on the control of the proteostasis network in health and diseases.

Chevet E, Pedeux R, Lotersztajn S.

Am J Physiol Cell Physiol. 2016 Aug 1;311(2):C163-5. doi: 10.1152/ajpcell.00130.2016. Epub 2016 May 25. No abstract available.


Role of the tumor microenvironment in regulating apoptosis and cancer progression.

Yaacoub K, Pedeux R, Tarte K, Guillaudeux T.

Cancer Lett. 2016 Aug 10;378(2):150-9. doi: 10.1016/j.canlet.2016.05.012. Epub 2016 May 17. Review.


Reply: Standardized procedure for bone marrow MSCs preparation for clinical use.

Bigot N, Sensebé L, Tarte K, Pedeux R.

Stem Cells. 2016 Jul;34(7):1994-5. doi: 10.1002/stem.2390. Epub 2016 May 17. No abstract available.


A concurrent ultra-fractionated radiation therapy and temozolomide treatment: A promising therapy for newly diagnosed, inoperable glioblastoma.

Beauchesne P, Quillien V, Faure G, Bernier V, Noel G, Quetin P, Gorlia T, Carnin C, Pedeux R.

Int J Cancer. 2016 Mar 15;138(6):1538-44. doi: 10.1002/ijc.29898. Epub 2015 Nov 20.


Hypoxia Differentially Modulates the Genomic Stability of Clinical-Grade ADSCs and BM-MSCs in Long-Term Culture.

Bigot N, Mouche A, Preti M, Loisel S, Renoud ML, Le Guével R, Sensebé L, Tarte K, Pedeux R.

Stem Cells. 2015 Dec;33(12):3608-20. doi: 10.1002/stem.2195. Epub 2015 Oct 8.


ING1b negatively regulates HIF1α protein levels in adipose-derived stromal cells by a SUMOylation-dependent mechanism.

Bigot N, Guérillon C, Loisel S, Bertheuil N, Sensebé L, Tarte K, Pedeux R.

Cell Death Dis. 2015 Jan 22;6:e1612. doi: 10.1038/cddis.2014.577.


SUMOylation of the ING1b tumor suppressor regulates gene transcription.

Satpathy S, Guérillon C, Kim TS, Bigot N, Thakur S, Bonni S, Riabowol K, Pedeux R.

Carcinogenesis. 2014 Oct;35(10):2214-23. doi: 10.1093/carcin/bgu126. Epub 2014 Jun 5.


The ING tumor suppressor genes: status in human tumors.

Guérillon C, Bigot N, Pedeux R.

Cancer Lett. 2014 Apr 1;345(1):1-16. doi: 10.1016/j.canlet.2013.11.016. Epub 2013 Dec 11. Review.


ING1 and ING2: multifaceted tumor suppressor genes.

Guérillon C, Larrieu D, Pedeux R.

Cell Mol Life Sci. 2013 Oct;70(20):3753-72. doi: 10.1007/s00018-013-1270-z. Epub 2013 Feb 15. Review.


ING2 controls the G1 to S-phase transition by regulating p21 expression.

Larrieu D, Ythier D, Brambilla C, Pedeux R.

Cell Cycle. 2010 Oct 1;9(19):3984-90. Epub 2010 Oct 1.


Sumoylation of ING2 regulates the transcription mediated by Sin3A.

Ythier D, Larrieu D, Binet R, Binda O, Brambilla C, Gazzeri S, Pedeux R.

Oncogene. 2010 Nov 4;29(44):5946-56. doi: 10.1038/onc.2010.325. Epub 2010 Aug 2.


Prolonged survival for patients with newly diagnosed, inoperable glioblastoma with 3-times daily ultrafractionated radiation therapy.

Beauchesne P, Bernier V, Carnin C, Taillandier L, Djabri M, Martin L, Michel X, Maire JP, Khalil T, Kerr C, Gorlia T, Stupp R, Pedeux R.

Neuro Oncol. 2010 Jun;12(6):595-602. doi: 10.1093/neuonc/noq008. Epub 2010 Feb 11.


Expression of candidate tumor suppressor gene ING2 is lost in non-small cell lung carcinoma.

Ythier D, Brambilla E, Binet R, Nissou D, Vesin A, de Fraipont F, Moro-Sibilot D, Lantuejoul S, Brambilla C, Gazzeri S, Pedeux R.

Lung Cancer. 2010 Aug;69(2):180-6. doi: 10.1016/j.lungcan.2009.11.006. Epub 2009 Dec 4.


WNT16B is a new marker of cellular senescence that regulates p53 activity and the phosphoinositide 3-kinase/AKT pathway.

Binet R, Ythier D, Robles AI, Collado M, Larrieu D, Fonti C, Brambilla E, Brambilla C, Serrano M, Harris CC, Pedeux R.

Cancer Res. 2009 Dec 15;69(24):9183-91. doi: 10.1158/0008-5472.CAN-09-1016.


SharING out the roles in replicatING DNA.

Larrieu D, Pedeux R.

Cell Cycle. 2009 Nov 15;8(22):3623-4. No abstract available.


ING2 controls the progression of DNA replication forks to maintain genome stability.

Larrieu D, Ythier D, Binet R, Brambilla C, Brambilla E, Sengupta S, Pedeux R.

EMBO Rep. 2009 Oct;10(10):1168-74. doi: 10.1038/embor.2009.180. Epub 2009 Sep 4.


Interference with netrin-1 and tumor cell death in non-small cell lung cancer.

Delloye-Bourgeois C, Brambilla E, Coissieux MM, Guenebeaud C, Pedeux R, Firlej V, Cabon F, Brambilla C, Mehlen P, Bernet A.

J Natl Cancer Inst. 2009 Feb 18;101(4):237-47. doi: 10.1093/jnci/djn491. Epub 2009 Feb 10.


The new tumor suppressor genes ING: genomic structure and status in cancer.

Ythier D, Larrieu D, Brambilla C, Brambilla E, Pedeux R.

Int J Cancer. 2008 Oct 1;123(7):1483-90. doi: 10.1002/ijc.23790. Review.


Proportion of skin surface area of children and young adults from 2 to 18 years old.

Boniol M, Verriest JP, Pedeux R, Doré JF.

J Invest Dermatol. 2008 Feb;128(2):461-4. Epub 2007 Aug 30.


Inhibitor of growth 4 suppresses cell spreading and cell migration by interacting with a novel binding partner, liprin alpha1.

Shen JC, Unoki M, Ythier D, Duperray A, Varticovski L, Kumamoto K, Pedeux R, Harris CC.

Cancer Res. 2007 Mar 15;67(6):2552-8.


UVB-induced G2 arrest of human melanocytes involves Cdc2 sequestration by Gadd45a in nuclear speckles.

Fayolle C, Pourchet J, Cohen A, Pedeux R, Puisieux A, Caron de Fromentel C, Dorè JF, Voeltzel T.

Cell Cycle. 2006 Aug;5(16):1859-64. Epub 2006 Aug 15.


Ultraviolet B sensitivity of peripheral lymphocytes as an independent risk factor for cutaneous melanoma.

Pedeux R, Sales F, Pourchet J, Kallassy M, Fayolle C, Boniol M, Severi G, Ghanem G, Nakazawa HN, Autier P, Doré JF.

Eur J Cancer. 2006 Jan;42(2):212-5. Epub 2005 Dec 7.


ING2 regulates the onset of replicative senescence by induction of p300-dependent p53 acetylation.

Pedeux R, Sengupta S, Shen JC, Demidov ON, Saito S, Onogi H, Kumamoto K, Wincovitch S, Garfield SH, McMenamin M, Nagashima M, Grossman SR, Appella E, Harris CC.

Mol Cell Biol. 2005 Aug;25(15):6639-48.


Tumor suppressor p53 represses transcription of RECQ4 helicase.

Sengupta S, Shimamoto A, Koshiji M, Pedeux R, Rusin M, Spillare EA, Shen JC, Huang LE, Lindor NM, Furuichi Y, Harris CC.

Oncogene. 2005 Mar 3;24(10):1738-48.


Sex differences in numbers of nevi on body sites of young European children: implications for the etiology of cutaneous melanoma.

Autier P, Boniol M, Severi G, Pedeux R, Grivegnée AR, Doré JF.

Cancer Epidemiol Biomarkers Prev. 2004 Dec;13(12):2003-5.


Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest.

Sengupta S, Robles AI, Linke SP, Sinogeeva NI, Zhang R, Pedeux R, Ward IM, Celeste A, Nussenzweig A, Chen J, Halazonetis TD, Harris CC.

J Cell Biol. 2004 Sep 13;166(6):801-13.


Intracerebral C6 glioma model in female hairless rats: assessment by using MRI and follow-up of irradiation.

Beauchesne PD, Pedeux RM, Bonmartin A, Bertrand S, Jouvet A, Kirchner AL, Revel R, Mornex F, Dore JF.

Anticancer Res. 2003 Sep-Oct;23(5A):3755-60.


Number and size of nevi are influenced by different sun exposure components: implications for the etiology of cutaneous melanoma (Belgium, Germany, France, Italy).

Autier P, Severi G, Pedeux R, Cattaruzza MS, Boniol M, Grivegnée A, Doré JF; European Organisation for Research and Treatment of Cancer Melanoma Group.

Cancer Causes Control. 2003 Jun;14(5):453-9.


p53 interacts with hRAD51 and hRAD54, and directly modulates homologous recombination.

Linke SP, Sengupta S, Khabie N, Jeffries BA, Buchhop S, Miska S, Henning W, Pedeux R, Wang XW, Hofseth LJ, Yang Q, Garfield SH, Stürzbecher HW, Harris CC.

Cancer Res. 2003 May 15;63(10):2596-605.


p29ING4 and p28ING5 bind to p53 and p300, and enhance p53 activity.

Shiseki M, Nagashima M, Pedeux RM, Kitahama-Shiseki M, Miura K, Okamura S, Onogi H, Higashimoto Y, Appella E, Yokota J, Harris CC.

Cancer Res. 2003 May 15;63(10):2373-8.


Human malignant glioma cell lines are sensitive to low radiation doses.

Beauchesne PD, Bertrand S, Branche R, Linke SP, Revel R, Dore JF, Pedeux RM.

Int J Cancer. 2003 May 20;105(1):33-40.


BLM helicase-dependent transport of p53 to sites of stalled DNA replication forks modulates homologous recombination.

Sengupta S, Linke SP, Pedeux R, Yang Q, Farnsworth J, Garfield SH, Valerie K, Shay JW, Ellis NA, Wasylyk B, Harris CC.

EMBO J. 2003 Mar 3;22(5):1210-22.


A novel PHD-finger motif protein, p47ING3, modulates p53-mediated transcription, cell cycle control, and apoptosis.

Nagashima M, Shiseki M, Pedeux RM, Okamura S, Kitahama-Shiseki M, Miura K, Yokota J, Harris CC.

Oncogene. 2003 Jan 23;22(3):343-50.


Re: DNA repair, dysplastic nevi, and sunlight sensitivity in the development of cutaneous malignant melanoma.

Pedeux R, Boniol M, Autier P, Doré JF.

J Natl Cancer Inst. 2002 May 15;94(10):772-3; author reply 773-4. No abstract available.


Specific induction of gadd45 in human melanocytes and melanoma cells after UVB irradiation.

Pedeux R, Lefort K, Cuenin C, Cortes U, Kellner K, Doré JF, Nakazawa H.

Int J Cancer. 2002 Apr 20;98(6):811-6.


DNA damage-inducible gene p33ING2 negatively regulates cell proliferation through acetylation of p53.

Nagashima M, Shiseki M, Miura K, Hagiwara K, Linke SP, Pedeux R, Wang XW, Yokota J, Riabowol K, Harris CC.

Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9671-6. Epub 2001 Jul 31.


The body site distribution of melanocytic naevi in 6-7 year old European children.

Autier P, Boniol M, Severi G, Giles G, Cattaruzza MS, Luther H, Renard F, Grivegnée AR, Pedeux R, Doré JF; EPIMEL.

Melanoma Res. 2001 Apr;11(2):123-31.


Intermediate-effect biomarkers in prevention of skin cancer.

Doré JF, Pedeux R, Boniol M, Chignol MC, Autier P.

IARC Sci Publ. 2001;154:81-91. Review.


RESPONSE: Re: Sunscreen Use and Duration of Sun Exposure: a Double-Blind, Randomized Trial.

Autier P, Pedeux R, Doré JF.

J Natl Cancer Inst. 1999 Dec 1;91(23):2047. No abstract available.


Thymidine dinucleotides induce S phase cell cycle arrest in addition to increased melanogenesis in human melanocytes.

Pedeux R, Al-Irani N, Marteau C, Pellicier F, Branche R, Ozturk M, Franchi J, Doré JF.

J Invest Dermatol. 1998 Sep;111(3):472-7.

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