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Items: 1 to 50 of 245

1.

Reduced Gene Expression of Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1α in Whole Blood in Euthyroid Patients One Year After Hemithyroidectomy for Benign Euthyroid Goiter.

Kristensen TT, Pedersen PL, Larsen J, Feldthusen AD, Jelstrup S, Ellervik C.

Horm Metab Res. 2019 Feb;51(2):127-133. doi: 10.1055/a-0822-3066. Epub 2019 Feb 13. German.

PMID:
30759490
2.

3-Bromopyruvate as a potent anticancer therapy in honor and memory of the late Professor André Goffeau.

Ko YH, Niedźwiecka K, Casal M, Pedersen PL, Ułaszewski S.

Yeast. 2019 Apr;36(4):211-221. doi: 10.1002/yea.3367. Epub 2018 Dec 13.

PMID:
30462852
3.

Comparing patient-reported outcomes entered at home versus at hospital, and testing touch screens for initial recruitment to scientific trials in arthritis patients.

Secher AE, Glintborg B, Gudbergsen H, Krogh NS, Sørensen IJ, Jensen DV, Christensen R, Skougaard M, Pedersen PL, Hetland ML.

Scand J Rheumatol. 2019 May;48(3):178-184. doi: 10.1080/03009742.2018.1522666. Epub 2018 Nov 16. Erratum in: Scand J Rheumatol. 2019 May;48(3):258.

PMID:
30444168
4.

Corrigendum to "Impaired Fertility Associated with Subclinical Hypothyroidism and Thyroid Autoimmunity: The Danish General Suburban Population Study".

Feldthusen AD, Pedersen PL, Larsen J, Toft Kristensen T, Ellervik C, Kvetny J.

J Pregnancy. 2017;2017:9864034. doi: 10.1155/2017/9864034. Epub 2017 Nov 5.

5.

Synthesis of Lipophilic Guanine N-9 Derivatives: Membrane Anchoring of Nucleobases Tailored to Fatty Acid Vesicles.

Wamberg MC, Pedersen PL, Löffler PMG, Albertsen AN, Maurer SE, Nielsen KA, Monnard PA.

Bioconjug Chem. 2017 Jul 19;28(7):1893-1905. doi: 10.1021/acs.bioconjchem.7b00228. Epub 2017 Jun 29.

PMID:
28587449
6.

The HK2 Dependent "Warburg Effect" and Mitochondrial Oxidative Phosphorylation in Cancer: Targets for Effective Therapy with 3-Bromopyruvate.

Lis P, Dyląg M, Niedźwiecka K, Ko YH, Pedersen PL, Goffeau A, Ułaszewski S.

Molecules. 2016 Dec 15;21(12). pii: E1730. Review.

7.

Glutathione may have implications in the design of 3-bromopyruvate treatment protocols for both fungal and algal infections as well as multiple myeloma.

Niedźwiecka K, Dyląg M, Augustyniak D, Majkowska-Skrobek G, Cal-Bąkowska M, Ko YH, Pedersen PL, Goffeau A, Ułaszewski S.

Oncotarget. 2016 Oct 4;7(40):65614-65626. doi: 10.18632/oncotarget.11592.

8.

Preparation of Ultracold Atom Clouds at the Shot Noise Level.

Gajdacz M, Hilliard AJ, Kristensen MA, Pedersen PL, Klempt C, Arlt JJ, Sherson JF.

Phys Rev Lett. 2016 Aug 12;117(7):073604. doi: 10.1103/PhysRevLett.117.073604. Epub 2016 Aug 12.

PMID:
27563964
9.

The anticancer agent 3-bromopyruvate: a simple but powerful molecule taken from the lab to the bedside.

Azevedo-Silva J, Queirós O, Baltazar F, Ułaszewski S, Goffeau A, Ko YH, Pedersen PL, Preto A, Casal M.

J Bioenerg Biomembr. 2016 Aug;48(4):349-62. doi: 10.1007/s10863-016-9670-z. Epub 2016 Jul 25. Review.

PMID:
27457582
10.

Screening the yeast genome for energetic metabolism pathways involved in a phenotypic response to the anti-cancer agent 3-bromopyruvate.

Lis P, Jurkiewicz P, Cal-Bąkowska M, Ko YH, Pedersen PL, Goffeau A, Ułaszewski S.

Oncotarget. 2016 Mar 1;7(9):10153-73. doi: 10.18632/oncotarget.7174.

11.

Designing a broad-spectrum integrative approach for cancer prevention and treatment.

Block KI, Gyllenhaal C, Lowe L, Amedei A, Amin ARMR, Amin A, Aquilano K, Arbiser J, Arreola A, Arzumanyan A, Ashraf SS, Azmi AS, Benencia F, Bhakta D, Bilsland A, Bishayee A, Blain SW, Block PB, Boosani CS, Carey TE, Carnero A, Carotenuto M, Casey SC, Chakrabarti M, Chaturvedi R, Chen GZ, Chen H, Chen S, Chen YC, Choi BK, Ciriolo MR, Coley HM, Collins AR, Connell M, Crawford S, Curran CS, Dabrosin C, Damia G, Dasgupta S, DeBerardinis RJ, Decker WK, Dhawan P, Diehl AME, Dong JT, Dou QP, Drew JE, Elkord E, El-Rayes B, Feitelson MA, Felsher DW, Ferguson LR, Fimognari C, Firestone GL, Frezza C, Fujii H, Fuster MM, Generali D, Georgakilas AG, Gieseler F, Gilbertson M, Green MF, Grue B, Guha G, Halicka D, Helferich WG, Heneberg P, Hentosh P, Hirschey MD, Hofseth LJ, Holcombe RF, Honoki K, Hsu HY, Huang GS, Jensen LD, Jiang WG, Jones LW, Karpowicz PA, Keith WN, Kerkar SP, Khan GN, Khatami M, Ko YH, Kucuk O, Kulathinal RJ, Kumar NB, Kwon BS, Le A, Lea MA, Lee HY, Lichtor T, Lin LT, Locasale JW, Lokeshwar BL, Longo VD, Lyssiotis CA, MacKenzie KL, Malhotra M, Marino M, Martinez-Chantar ML, Matheu A, Maxwell C, McDonnell E, Meeker AK, Mehrmohamadi M, Mehta K, Michelotti GA, Mohammad RM, Mohammed SI, Morre DJ, Muralidhar V, Muqbil I, Murphy MP, Nagaraju GP, Nahta R, Niccolai E, Nowsheen S, Panis C, Pantano F, Parslow VR, Pawelec G, Pedersen PL, Poore B, Poudyal D, Prakash S, Prince M, Raffaghello L, Rathmell JC, Rathmell WK, Ray SK, Reichrath J, Rezazadeh S, Ribatti D, Ricciardiello L, Robey RB, Rodier F, Rupasinghe HPV, Russo GL, Ryan EP, Samadi AK, Sanchez-Garcia I, Sanders AJ, Santini D, Sarkar M, Sasada T, Saxena NK, Shackelford RE, Shantha Kumara HMC, Sharma D, Shin DM, Sidransky D, Siegelin MD, Signori E, Singh N, Sivanand S, Sliva D, Smythe C, Spagnuolo C, Stafforini DM, Stagg J, Subbarayan PR, Sundin T, Talib WH, Thompson SK, Tran PT, Ungefroren H, Vander Heiden MG, Venkateswaran V, Vinay DS, Vlachostergios PJ, Wang Z, Wellen KE, Whelan RL, Yang ES, Yang H, Yang X, Yaswen P, Yedjou C, Yin X, Zhu J, Zollo M.

Semin Cancer Biol. 2015 Dec;35 Suppl:S276-S304. doi: 10.1016/j.semcancer.2015.09.007. Review.

12.

Dysregulated metabolism contributes to oncogenesis.

Hirschey MD, DeBerardinis RJ, Diehl AME, Drew JE, Frezza C, Green MF, Jones LW, Ko YH, Le A, Lea MA, Locasale JW, Longo VD, Lyssiotis CA, McDonnell E, Mehrmohamadi M, Michelotti G, Muralidhar V, Murphy MP, Pedersen PL, Poore B, Raffaghello L, Rathmell JC, Sivanand S, Vander Heiden MG, Wellen KE; Target Validation Team.

Semin Cancer Biol. 2015 Dec;35 Suppl:S129-S150. doi: 10.1016/j.semcancer.2015.10.002. Epub 2015 Oct 8. Review.

13.

Impaired Fertility Associated with Subclinical Hypothyroidism and Thyroid Autoimmunity: The Danish General Suburban Population Study.

Feldthusen AD, Pedersen PL, Larsen J, Toft Kristensen T, Ellervik C, Kvetny J.

J Pregnancy. 2015;2015:132718. doi: 10.1155/2015/132718. Epub 2015 Aug 17. Erratum in: J Pregnancy. 2017;2017:9864034.

14.

The cytotoxicity of 3-bromopyruvate in breast cancer cells depends on extracellular pH.

Azevedo-Silva J, Queirós O, Ribeiro A, Baltazar F, Young KH, Pedersen PL, Preto A, Casal M.

Biochem J. 2015 Apr 15;467(2):247-58. doi: 10.1042/BJ20140921.

PMID:
25641640
15.

Weight Gain and Serum TSH Increase within the Reference Range after Hemithyroidectomy Indicate Lowered Thyroid Function.

Toft Kristensen T, Larsen J, Pedersen PL, Feldthusen AD, Ellervik C, Jelstrup S, Kvetny J.

J Thyroid Res. 2014;2014:892573. doi: 10.1155/2014/892573. Epub 2014 May 14.

16.

Persistent cellular metabolic changes after hemithyroidectomy for benign euthyroid goiter.

Toft Kristensen T, Larsen J, Pedersen PL, Feldthusen AD, Ellervik C, Jelstrup S, Kvetny J.

Eur Thyroid J. 2014 Mar;3(1):10-6. doi: 10.1159/000357943. Epub 2014 Mar 12.

17.

Killing multiple myeloma cells with the small molecule 3-bromopyruvate: implications for therapy.

Majkowska-Skrobek G, Augustyniak D, Lis P, Bartkowiak A, Gonchar M, Ko YH, Pedersen PL, Goffeau A, Ułaszewski S.

Anticancer Drugs. 2014 Jul;25(6):673-82. doi: 10.1097/CAD.0000000000000094.

PMID:
24557015
18.

Pregnancy-induced alterations in mitochondrial function in euthyroid pregnant women and pregnant women with subclinical hypothyroidism; relation to adverse outcome.

Feldthusen AD, Larsen J, Pedersen PL, Toft Kristensen T, Kvetny J.

J Clin Transl Endocrinol. 2013 Dec 24;1(1):e13-e17. doi: 10.1016/j.jcte.2013.12.003. eCollection 2014 Mar.

19.

Ferrous bisglycinate 25 mg iron is as effective as ferrous sulfate 50 mg iron in the prophylaxis of iron deficiency and anemia during pregnancy in a randomized trial.

Milman N, Jønsson L, Dyre P, Pedersen PL, Larsen LG.

J Perinat Med. 2014 Mar;42(2):197-206. doi: 10.1515/jpm-2013-0153.

PMID:
24152889
20.

Non-destructive Faraday imaging of dynamically controlled ultracold atoms.

Gajdacz M, Pedersen PL, Mørch T, Hilliard AJ, Arlt J, Sherson JF.

Rev Sci Instrum. 2013 Aug;84(8):083105. doi: 10.1063/1.4818913.

PMID:
24007051
21.

3-Bromopyruvate: a novel antifungal agent against the human pathogen Cryptococcus neoformans.

Dyląg M, Lis P, Niedźwiecka K, Ko YH, Pedersen PL, Goffeau A, Ułaszewski S.

Biochem Biophys Res Commun. 2013 May 3;434(2):322-7. doi: 10.1016/j.bbrc.2013.02.125. Epub 2013 Mar 26.

PMID:
23541578
22.

Basal and T₃-induced ROS production in lymphocyte mitochondria is increased in type 2 diabetic patients.

Anthonsen S, Larsen J, Pedersen PL, Dalgaard LT, Kvetny J.

Horm Metab Res. 2013 Apr;45(4):261-6. doi: 10.1055/s-0032-1327590. Epub 2012 Sep 26.

PMID:
23015613
23.

Human Hepatocellular Carcinoma Metabolism: Imaging by Hyperpolarized 13C Magnetic Resonance Spectroscopy.

Darpolor MM, Kaplan DE, Pedersen PL, Glickson JD.

J Liver Disease Transplant. 2012 Sep 1;1(1). doi: 10.4172/2325-9612.1000101.

24.

Mitochondria in relation to cancer metastasis: introduction to a mini-review series.

Pedersen PL.

J Bioenerg Biomembr. 2012 Dec;44(6):615-7. doi: 10.1007/s10863-012-9470-z.

PMID:
22926290
26.

Transport and cytotoxicity of the anticancer drug 3-bromopyruvate in the yeast Saccharomyces cerevisiae.

Lis P, Zarzycki M, Ko YH, Casal M, Pedersen PL, Goffeau A, Ułaszewski S.

J Bioenerg Biomembr. 2012 Feb;44(1):155-61. doi: 10.1007/s10863-012-9421-8. Epub 2012 Feb 23.

PMID:
22359102
27.

Butyrate activates the monocarboxylate transporter MCT4 expression in breast cancer cells and enhances the antitumor activity of 3-bromopyruvate.

Queirós O, Preto A, Pacheco A, Pinheiro C, Azevedo-Silva J, Moreira R, Pedro M, Ko YH, Pedersen PL, Baltazar F, Casal M.

J Bioenerg Biomembr. 2012 Feb;44(1):141-53. doi: 10.1007/s10863-012-9418-3. Epub 2012 Feb 17.

PMID:
22350013
28.

A translational study "case report" on the small molecule "energy blocker" 3-bromopyruvate (3BP) as a potent anticancer agent: from bench side to bedside.

Ko YH, Verhoeven HA, Lee MJ, Corbin DJ, Vogl TJ, Pedersen PL.

J Bioenerg Biomembr. 2012 Feb;44(1):163-70. doi: 10.1007/s10863-012-9417-4. Epub 2012 Feb 11.

PMID:
22328020
29.

Mitochondrial ATP synthase catalytic mechanism: a novel visual comparative structural approach emphasizes pivotal roles for Mg²⁺ and P-loop residues in making ATP.

Blum DJ, Ko YH, Pedersen PL.

Biochemistry. 2012 Feb 21;51(7):1532-46. doi: 10.1021/bi201595v. Epub 2012 Feb 9.

PMID:
22243519
30.

Bcl-xL regulates mitochondrial energetics by stabilizing the inner membrane potential.

Chen YB, Aon MA, Hsu YT, Soane L, Teng X, McCaffery JM, Cheng WC, Qi B, Li H, Alavian KN, Dayhoff-Brannigan M, Zou S, Pineda FJ, O'Rourke B, Ko YH, Pedersen PL, Kaczmarek LK, Jonas EA, Hardwick JM.

J Cell Biol. 2011 Oct 17;195(2):263-76. doi: 10.1083/jcb.201108059. Epub 2011 Oct 10.

31.
32.

Voltage dependent anion channel-1 (VDAC-1) as an anti-cancer target.

Mathupala SP, Pedersen PL.

Cancer Biol Ther. 2010 Jun 15;9(12):1053-6. Epub 2010 Jun 21. No abstract available.

33.

Correlation between thymidylate synthase gene variants, RNA and protein levels in primary colorectal adenocarcinomas.

Kristensen MH, Weidinger M, Bzorek M, Pedersen PL, Mejer J.

J Int Med Res. 2010 Mar-Apr;38(2):484-97.

PMID:
20515563
34.

The pivotal roles of mitochondria in cancer: Warburg and beyond and encouraging prospects for effective therapies.

Mathupala SP, Ko YH, Pedersen PL.

Biochim Biophys Acta. 2010 Jun-Jul;1797(6-7):1225-30. doi: 10.1016/j.bbabio.2010.03.025. Epub 2010 Apr 8. Review.

35.

Subclinical hypothyroidism affects mitochondrial function.

Kvetny J, Wilms L, Pedersen PL, Larsen J.

Horm Metab Res. 2010 May;42(5):324-7. doi: 10.1055/s-0030-1248261. Epub 2010 Feb 22.

PMID:
20178065
36.

Measure of expression of mitochondrial related genes in human mononuclear blood cells, adipose white tissue and smooth muscle cells.

Fabricius MH, Wilms LK, Larsen J, Pedersen PL, Anthonsen S, Kvetny J.

Clin Chim Acta. 2010 May 2;411(9-10):749-53. doi: 10.1016/j.cca.2010.02.005. Epub 2010 Feb 10.

PMID:
20149788
37.

Evidence of mitochondrial dysfunction in obese adolescents.

Wilms L, Larsen J, Pedersen PL, Kvetny J.

Acta Paediatr. 2010 Jun;99(6):906-11. doi: 10.1111/j.1651-2227.2009.01635.x. Epub 2009 Dec 15.

PMID:
20015331
38.

Mitochondrial matters of the brain: amyloid formation and Alzheimer's disease introduction.

Pedersen PL.

J Bioenerg Biomembr. 2009 Oct;41(5):403-5. doi: 10.1007/s10863-009-9248-0.

PMID:
19882355
39.

Mitochondrial matters of the heart: a plethora of regulatory modes to maintain function for a long lifetime.

Pedersen PL.

J Bioenerg Biomembr. 2009 Apr;41(2):95-8. doi: 10.1007/s10863-009-9219-5. Review.

PMID:
19513821
40.

Hexokinase-2 bound to mitochondria: cancer's stygian link to the "Warburg Effect" and a pivotal target for effective therapy.

Mathupala SP, Ko YH, Pedersen PL.

Semin Cancer Biol. 2009 Feb;19(1):17-24. doi: 10.1016/j.semcancer.2008.11.006. Epub 2008 Dec 3. Review.

41.

ATP synthase and the actions of inhibitors utilized to study its roles in human health, disease, and other scientific areas.

Hong S, Pedersen PL.

Microbiol Mol Biol Rev. 2008 Dec;72(4):590-641, Table of Contents. doi: 10.1128/MMBR.00016-08. Review.

43.

Transport ATPases into the year 2008: a brief overview related to types, structures, functions and roles in health and disease.

Pedersen PL.

J Bioenerg Biomembr. 2007 Dec;39(5-6):349-55. doi: 10.1007/s10863-007-9123-9. Review.

PMID:
18175209
45.

The cancer cell's "power plants" as promising therapeutic targets: an overview.

Pedersen PL.

J Bioenerg Biomembr. 2007 Feb;39(1):1-12. Review.

PMID:
17404823
46.

Proteomic analysis of pharmacological preconditioning: novel protein targets converge to mitochondrial metabolism pathways.

Arrell DK, Elliott ST, Kane LA, Guo Y, Ko YH, Pedersen PL, Robinson J, Murata M, Murphy AM, Marbán E, Van Eyk JE.

Circ Res. 2006 Sep 29;99(7):706-14. Epub 2006 Aug 31.

PMID:
16946135
47.
48.

Transport ATPases: structure, motors, mechanism and medicine: a brief overview.

Pedersen PL.

J Bioenerg Biomembr. 2005 Dec;37(6):349-57. Review.

PMID:
16691464
49.

Mitochondrial ATP synthase. Crystal structure of the catalytic F1 unit in a vanadate-induced transition-like state and implications for mechanism.

Chen C, Saxena AK, Simcoke WN, Garboczi DN, Pedersen PL, Ko YH.

J Biol Chem. 2006 May 12;281(19):13777-83. Epub 2006 Mar 10.

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