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Whole-genome analysis for effective clinical diagnosis and gene discovery in early infantile epileptic encephalopathy.

Ostrander BEP, Butterfield RJ, Pedersen BS, Farrell AJ, Layer RM, Ward A, Miller C, DiSera T, Filloux FM, Candee MS, Newcomb T, Bonkowsky JL, Marth GT, Quinlan AR.

NPJ Genom Med. 2018 Aug 13;3:22. doi: 10.1038/s41525-018-0061-8. eCollection 2018.


Antineoplastic treatment with crizotinib during pregnancy: a case report.

Jensen KH, Persson G, Storgaard L, Nielsen BB, Pedersen BW, Maroun LL, Huitema A, Pøhl M.

Acta Oncol. 2018 Aug 11:1-2. doi: 10.1080/0284186X.2018.1497302. [Epub ahead of print] No abstract available.


Single Cell Analysis Identifies the miRNA Expression Profile of a Subpopulation of Muscle Precursor Cells Unique to Humans With Type 2 Diabetes.

Henriksen TI, Heywood SE, Hansen NS, Pedersen BK, Scheele CC, Nielsen S.

Front Physiol. 2018 Jul 11;9:883. doi: 10.3389/fphys.2018.00883. eCollection 2018.


GOATOOLS: A Python library for Gene Ontology analyses.

Klopfenstein DV, Zhang L, Pedersen BS, Ramírez F, Warwick Vesztrocy A, Naldi A, Mungall CJ, Yunes JM, Botvinnik O, Weigel M, Dampier W, Dessimoz C, Flick P, Tang H.

Sci Rep. 2018 Jul 18;8(1):10872. doi: 10.1038/s41598-018-28948-z.


Anxiety and Depression among Pregnant Women and Mothers of Children Under one Year in Sindupalchowk District.

Aryal KK, Alvik A, Thapa N, Mehata S, Roka T, Thapa P, Pandey P, Pedersen BS.

J Nepal Health Res Counc. 2018 Jul 3;16(2):195-204.


Angiogenin and Osteoprotegerin are type II muscle specific myokines protecting pancreatic beta-cells against proinflammatory cytokines.

Rutti S, Dusaulcy R, Hansen JS, Howald C, Dermitzakis ET, Pedersen BK, Pinget M, Plomgaard P, Bouzakri K.

Sci Rep. 2018 Jul 3;8(1):10072. doi: 10.1038/s41598-018-28117-2.


Ectopic lipid deposition is associated with insulin resistance in postmenopausal women.

Abildgaard J, Danielsen ER, Dorph E, Thomsen C, Juul A, Ewertsen C, Pedersen BK, Pedersen AT, Ploug T, Lindegaard B.

J Clin Endocrinol Metab. 2018 Jun 7. doi: 10.1210/jc.2018-00554. [Epub ahead of print]


Effects of erythropoietin on body composition and fat-glucose metabolism in patients with affective disorders.

Vinberg M, Højman P, Pedersen BK, Kessing LV, Miskowiak KW.

Acta Neuropsychiatr. 2018 Jun 8:1-8. doi: 10.1017/neu.2018.16. [Epub ahead of print]


Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis.

Sustarsic EG, Ma T, Lynes MD, Larsen M, Karavaeva I, Havelund JF, Nielsen CH, Jedrychowski MP, Moreno-Torres M, Lundh M, Plucinska K, Jespersen NZ, Grevengoed TJ, Kramar B, Peics J, Hansen JB, Shamsi F, Forss I, Neess D, Keipert S, Wang J, Stohlmann K, Brandslund I, Christensen C, Jørgensen ME, Linneberg A, Pedersen O, Kiebish MA, Qvortrup K, Han X, Pedersen BK, Jastroch M, Mandrup S, Kjær A, Gygi SP, Hansen T, Gillum MP, Grarup N, Emanuelli B, Nielsen S, Scheele C, Tseng YH, Færgeman NJ, Gerhart-Hines Z.

Cell Metab. 2018 Jul 3;28(1):159-174.e11. doi: 10.1016/j.cmet.2018.05.003. Epub 2018 May 31.


SV-plaudit: A cloud-based framework for manually curating thousands of structural variants.

Belyeu JR, Nicholas TJ, Pedersen BS, Sasani TA, Havrilla JM, Kravitz SN, Conway ME, Lohman BK, Quinlan AR, Layer RM.

Gigascience. 2018 Jul 1;7(7). doi: 10.1093/gigascience/giy064.


Effect of endurance versus resistance training on local muscle and systemic inflammation and oxidative stress in COPD.

Ryrsø CK, Thaning P, Siebenmann C, Lundby C, Lange P, Pedersen BK, Hellsten Y, Iepsen UW.

Scand J Med Sci Sports. 2018 May 26. doi: 10.1111/sms.13227. [Epub ahead of print]


Ictal and interictal electric source imaging in pre-surgical evaluation: a prospective study.

Sharma P, Scherg M, Pinborg LH, Fabricius M, Rubboli G, Pedersen B, Leffers AM, Uldall P, Jespersen B, Brennum J, Henriksen OM, Beniczky S.

Eur J Neurol. 2018 Sep;25(9):1154-1160. doi: 10.1111/ene.13676. Epub 2018 Jun 8.


Interleukin-6 Delays Gastric Emptying in Humans with Direct Effects on Glycemic Control.

Lang Lehrskov L, Lyngbaek MP, Soederlund L, Legaard GE, Ehses JA, Heywood SE, Wewer Albrechtsen NJ, Holst JJ, Karstoft K, Pedersen BK, Ellingsgaard H.

Cell Metab. 2018 Jun 5;27(6):1201-1211.e3. doi: 10.1016/j.cmet.2018.04.008. Epub 2018 May 3.


Træning af brystcanceroverlevere – med hvilket formål?

Højman P, Pedersen BK.

Ugeskr Laeger. 2018 Apr 30;180(18). pii: V69868. Danish. No abstract available.


The role of exercise combined with tocilizumab in visceral and epicardial adipose tissue and gastric emptying rate in abdominally obese participants: protocol for a randomised controlled trial.

Christensen RH, Wedell-Neergaard AS, Lehrskov LL, Legård GE, Dorph EB, Nymand S, Ball MK, Zacho M, Christensen R, Ellingsgaard H, Rosenmeier JB, Krogh-Madsen R, Pedersen BK, Karstoft K.

Trials. 2018 May 2;19(1):266. doi: 10.1186/s13063-018-2637-0.


hts-nim: scripting high-performance genomic analyses.

Pedersen BS, Quinlan AR.

Bioinformatics. 2018 Apr 30. doi: 10.1093/bioinformatics/bty358. [Epub ahead of print]


Female sex hormones are necessary for the metabolic effects mediated by loss of Interleukin 18 signaling.

Lindegaard B, Abildgaard J, Heywood SE, Pedersen BK, Febbraio MA.

Mol Metab. 2018 Jun;12:89-97. doi: 10.1016/j.molmet.2018.04.005. Epub 2018 Apr 12.


The "Interval Walking in Colorectal Cancer" (I-WALK-CRC) study: Design, methods and recruitment results of a randomized controlled feasibility trial.

Banck-Petersen A, Olsen CK, Djurhuus SS, Herrstedt A, Thorsen-Streit S, Ried-Larsen M, Østerlind K, Osterkamp J, Krarup PM, Vistisen K, Mosgaard CS, Pedersen BK, Højman P, Christensen JF.

Contemp Clin Trials Commun. 2018 Feb 6;9:143-150. doi: 10.1016/j.conctc.2018.01.008. eCollection 2018 Mar.


Pelvic insufficiency fractures frequently occur following preoperative chemo-radiotherapy for rectal cancer - a nationwide MRI study.

Jørgensen JB, Bondeven P, Iversen LH, Laurberg S, Pedersen BG.

Colorectal Dis. 2018 Apr 19. doi: 10.1111/codi.14224. [Epub ahead of print]


Physical Activity and Exercise Therapy Benefit More Than Just Symptoms and Impairments in People With Hip and Knee Osteoarthritis.

Skou ST, Pedersen BK, Abbott JH, Patterson B, Barton C.

J Orthop Sports Phys Ther. 2018 Jun;48(6):439-447. doi: 10.2519/jospt.2018.7877. Epub 2018 Apr 18.


Investigating Changes in Weight and Body Composition Among Women in Adjuvant Treatment for Breast Cancer: A Scoping Review.

Pedersen B, Delmar C, Lörincz T, Falkmer U, Grønkjær M.

Cancer Nurs. 2018 Apr 12. doi: 10.1097/NCC.0000000000000590. [Epub ahead of print]


Cardiorespiratory fitness and the metabolic syndrome: Roles of inflammation and abdominal obesity.

Wedell-Neergaard AS, Krogh-Madsen R, Petersen GL, Hansen ÅM, Pedersen BK, Lund R, Bruunsgaard H.

PLoS One. 2018 Mar 28;13(3):e0194991. doi: 10.1371/journal.pone.0194991. eCollection 2018.


Two spin-canting textures in the antiferromagnetic phase AF1 of MnWO4 based on the new polar atomistic model in P2.

Park SH, Liu BQ, Behal D, Pedersen B, Schneidewind A.

J Phys Condens Matter. 2018 Apr 4;30(13):135802. doi: 10.1088/1361-648X/aaaeae. Epub 2018 Mar 2.


Why prescribe exercise as therapy in type 2 diabetes? We have a pill for that!

Ried-Larsen M, MacDonald CS, Johansen MY, Hansen KB, Christensen R, Almdal TP, Pedersen BK, Karstoft K.

Diabetes Metab Res Rev. 2018 Jul;34(5):e2999. doi: 10.1002/dmrr.2999. Epub 2018 Mar 24. Review.


Design of the Growth hormone deficiency and Efficacy of Treatment (GET) score and non-interventional proof of concept study.

Kann PH, Bergmann S, Bidlingmaier M, Dimopoulou C, Pedersen BT, Stalla GK, Weber MM, Meckes-Ferber S.

BMC Endocr Disord. 2018 Feb 13;18(1):10. doi: 10.1186/s12902-018-0237-3.


Nanopore sequencing and assembly of a human genome with ultra-long reads.

Jain M, Koren S, Miga KH, Quick J, Rand AC, Sasani TA, Tyson JR, Beggs AD, Dilthey AT, Fiddes IT, Malla S, Marriott H, Nieto T, O'Grady J, Olsen HE, Pedersen BS, Rhie A, Richardson H, Quinlan AR, Snutch TP, Tee L, Paten B, Phillippy AM, Simpson JT, Loman NJ, Loose M.

Nat Biotechnol. 2018 Apr;36(4):338-345. doi: 10.1038/nbt.4060. Epub 2018 Jan 29.


Publisher Correction: Combating subclonal evolution of resistant cancer phenotypes.

Brady SW, McQuerry JA, Qiao Y, Piccolo SR, Shrestha G, Jenkins DF, Layer RM, Pedersen BS, Miller RH, Esch A, Selitsky SR, Parker JS, Anderson LA, Dalley BK, Factor RE, Reddy CB, Boltax JP, Li DY, Moos PJ, Gray JW, Heiser LM, Buys SS, Cohen AL, Johnson WE, Quinlan AR, Marth G, Werner TL, Bild AH.

Nat Commun. 2018 Feb 5;9(1):572. doi: 10.1038/s41467-017-02383-6.


Sarcopenia and Postoperative Complication Risk in Gastrointestinal Surgical Oncology: A Meta-analysis.

Simonsen C, de Heer P, Bjerre ED, Suetta C, Hojman P, Pedersen BK, Svendsen LB, Christensen JF.

Ann Surg. 2018 Jul;268(1):58-69. doi: 10.1097/SLA.0000000000002679.


Comparative Effectiveness of Low-Volume Time-Efficient Resistance Training Versus Endurance Training in Patients With Heart Failure.

Munch GW, Rosenmeier JB, Petersen M, Rinnov AR, Iepsen UW, Pedersen BK, Mortensen SP.

J Cardiopulm Rehabil Prev. 2018 May;38(3):175-181. doi: 10.1097/HCR.0000000000000304.


Low fitness is associated with abdominal adiposity and low-grade inflammation independent of BMI.

Wedell-Neergaard AS, Eriksen L, Grønbæk M, Pedersen BK, Krogh-Madsen R, Tolstrup J.

PLoS One. 2018 Jan 17;13(1):e0190645. doi: 10.1371/journal.pone.0190645. eCollection 2018.


Low expression of IL-18 and IL-18 receptor in human skeletal muscle is associated with systemic and intramuscular lipid metabolism-Role of HIV lipodystrophy.

Lindegaard B, Hvid T, Wolsk Mygind H, Mortensen OH, Grøndal T, Abildgaard J, Gerstoft J, Pedersen BK, Baranowski M.

PLoS One. 2018 Jan 17;13(1):e0186755. doi: 10.1371/journal.pone.0186755. eCollection 2018. Erratum in: PLoS One. 2018 Apr 17;13(4):e0196241.


Methylene-tetrahydrofolate reductase contributes to allergic airway disease.

Eyring KR, Pedersen BS, Maclean KN, Stabler SP, Yang IV, Schwartz DA.

PLoS One. 2018 Jan 12;13(1):e0190916. doi: 10.1371/journal.pone.0190916. eCollection 2018.


Experiences of living kidney donors during the donation process.

Agerskov H, Bistrup C, Ludvigsen MS, Pedersen BD.

J Ren Care. 2018 Jun;44(2):96-105. doi: 10.1111/jorc.12233. Epub 2018 Jan 10.


GIGGLE: a search engine for large-scale integrated genome analysis.

Layer RM, Pedersen BS, DiSera T, Marth GT, Gertz J, Quinlan AR.

Nat Methods. 2018 Feb;15(2):123-126. doi: 10.1038/nmeth.4556. Epub 2018 Jan 8.


Intensive Lifestyle Intervention for Type 2 Diabetes-Reply.

Ried-Larsen M, Johansen MY, Pedersen BK.

JAMA. 2017 Dec 26;318(24):2494-2495. doi: 10.1001/jama.2017.17240. No abstract available.


The effect on glycaemic control of low-volume high-intensity interval training versus endurance training in individuals with type 2 diabetes.

Winding KM, Munch GW, Iepsen UW, Van Hall G, Pedersen BK, Mortensen SP.

Diabetes Obes Metab. 2018 May;20(5):1131-1139. doi: 10.1111/dom.13198. Epub 2018 Jan 31.


Multi-parametric magnetic resonance imaging monitoring patients in active surveillance for prostate cancer: a prospective cohort study.

Elkjær MC, Andersen MH, Høyer S, Pedersen BG, Borre M.

Scand J Urol. 2018 Feb;52(1):8-13. doi: 10.1080/21681805.2017.1409265. Epub 2017 Dec 7.


Medication and care in Alzheimer's patients in the acute care setting: A qualitative analysis.

Jensen AM, Pedersen BD, Olsen RB, Hounsgaard L.

Dementia (London). 2017 Jan 1:1471301217743306. doi: 10.1177/1471301217743306. [Epub ahead of print]


Effect of 6 wk of high-intensity one-legged cycling on functional sympatholysis and ATP signaling in patients with heart failure.

Munch GW, Iepsen UW, Ryrsø CK, Rosenmeier JB, Pedersen BK, Mortensen SP.

Am J Physiol Heart Circ Physiol. 2018 Mar 1;314(3):H616-H626. doi: 10.1152/ajpheart.00379.2017. Epub 2017 Nov 22.


Cholecystectomy for uncomplicated gallbladder stones does not follow evidence-based recommendations.

Pedersen B, Ellebæk MB, Dorfelt A, Qvist N.

Dan Med J. 2017 Nov;64(11). pii: A5411.


Mosdepth: quick coverage calculation for genomes and exomes.

Pedersen BS, Quinlan AR.

Bioinformatics. 2018 Mar 1;34(5):867-868. doi: 10.1093/bioinformatics/btx699.


Combating subclonal evolution of resistant cancer phenotypes.

Brady SW, McQuerry JA, Qiao Y, Piccolo SR, Shrestha G, Jenkins DF, Layer RM, Pedersen BS, Miller RH, Esch A, Selitsky SR, Parker JS, Anderson LA, Dalley BK, Factor RE, Reddy CB, Boltax JP, Li DY, Moos PJ, Gray JW, Heiser LM, Buys SS, Cohen AL, Johnson WE, Quinlan AR, Marth G, Werner TL, Bild AH.

Nat Commun. 2017 Nov 1;8(1):1231. doi: 10.1038/s41467-017-01174-3. Erratum in: Nat Commun. 2018 Feb 5;9(1):572.


Molecular Mechanisms Linking Exercise to Cancer Prevention and Treatment.

Hojman P, Gehl J, Christensen JF, Pedersen BK.

Cell Metab. 2018 Jan 9;27(1):10-21. doi: 10.1016/j.cmet.2017.09.015. Epub 2017 Oct 19. Review.


Indexcov: fast coverage quality control for whole-genome sequencing.

Pedersen BS, Collins RL, Talkowski ME, Quinlan AR.

Gigascience. 2017 Nov 1;6(11):1-6. doi: 10.1093/gigascience/gix090.


New high-throughput measurement systems for radioactive wastes segregation and free release.

Suran J, Kovar P, Smoldasova J, Solc J, Skala L, Arnold D, Jerome S, de Felice P, Pedersen B, Bogucarska T, Tzika F, van Ammel R.

Appl Radiat Isot. 2017 Dec;130:252-259. doi: 10.1016/j.apradiso.2017.09.043. Epub 2017 Sep 28.


Angiopoietin-like protein 4 is an exercise-induced hepatokine in humans, regulated by glucagon and cAMP.

Ingerslev B, Hansen JS, Hoffmann C, Clemmesen JO, Secher NH, Scheler M, Hrabĕ de Angelis M, Häring HU, Pedersen BK, Weigert C, Plomgaard P.

Mol Metab. 2017 Oct;6(10):1286-1295. doi: 10.1016/j.molmet.2017.06.018. Epub 2017 Jul 8.


Muscle α-adrenergic responsiveness during exercise and ATP-induced vasodilation in chronic obstructive pulmonary disease patients.

Iepsen UW, Munch GW, Ryrsø CK, Secher NH, Lange P, Thaning P, Pedersen BK, Mortensen SP.

Am J Physiol Heart Circ Physiol. 2018 Feb 1;314(2):H180-H187. doi: 10.1152/ajpheart.00398.2017. Epub 2017 Oct 13.


Distribution of Ixodes ricinus ticks and prevalence of tick-borne encephalitis virus among questing ticks in the Arctic Circle region of northern Norway.

Soleng A, Edgar KS, Paulsen KM, Pedersen BN, Okbaldet YB, Skjetne IEB, Gurung D, Vikse R, Andreassen ÅK.

Ticks Tick Borne Dis. 2018 Jan;9(1):97-103. doi: 10.1016/j.ttbdis.2017.10.002. Epub 2017 Oct 8.


Voluntary Wheel Running Reduces the Acute Inflammatory Response to Liver Carcinogen in a Sex-specific Manner.

Bay ML, Gehl J, Pedersen BK, Hojman P.

Cancer Prev Res (Phila). 2017 Dec;10(12):719-728. doi: 10.1158/1940-6207.CAPR-17-0075. Epub 2017 Sep 26.


Exercise-Induced Catecholamines Activate the Hippo Tumor Suppressor Pathway to Reduce Risks of Breast Cancer Development.

Dethlefsen C, Hansen LS, Lillelund C, Andersen C, Gehl J, Christensen JF, Pedersen BK, Hojman P.

Cancer Res. 2017 Sep 15;77(18):4894-4904. doi: 10.1158/0008-5472.CAN-16-3125.

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